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1. 发明申请

US20070097366A1 Optical system and method for detecting particles 审中-公开
标题翻译：用于检测颗粒的光学系统和方法
公开(公告)号：US20070097366A1
公开(公告)日：2007-05-03
申请号：US11262210
申请日：2005-10-31
申请人： Steven LeBoeuf , Alexei Vertiatchikh , Stanton Weaver , Radislav Potyrailo , Xian-An Cao
发明人： Steven LeBoeuf , Alexei Vertiatchikh , Stanton Weaver , Radislav Potyrailo , Xian-An Cao
IPC分类号： G01N21/00
CPC分类号： G01N21/6486 , G01N21/15 , G01N21/532 , G01N21/645
摘要： Embodiments of the invention include a particle detection system that includes a light emitting source, a non-collimating reflector, a collimating reflector, and a detector. Light from the light emitting source is directed by the non-collimating reflector to an area through which a particle stream may be transmitted. Fluorescent light from the light striking particles is redirected to the collimating reflector and then on to the detector. Other embodiments include a single pump used to pull a pair of fluid flows through the detection system. Other embodiments include a plurality of light emitting sources whose light is directed to a particle stream by a single reflector. Other embodiments include a method for detecting particles.
摘要翻译：本发明的实施例包括一种粒子检测系统，其包括发光源，非准直反射器，准直反射器和检测器。来自发光源的光由非准直反射器引导到可以传播颗粒物流的区域。来自光撞击颗粒的荧光被重定向到准直反射器，然后被引导到检测器上。其他实施例包括用于拉动一对流体流过检测系统的单个泵。其他实施例包括多个发光源，其光通过单个反射器被引导到颗粒流。其他实施方案包括用于检测颗粒的方法。

2. 发明申请

US20070098029A1 System for emission of electromagnetic radiation, and method for making 失效
标题翻译：电磁辐射发射系统及制作方法
公开(公告)号：US20070098029A1
公开(公告)日：2007-05-03
申请号：US11260415
申请日：2005-10-27
申请人： Steven LeBoeuf , Radislav Potyrailo , William Huber , Rui Chen , Todd Tolliver , Alexei Vertiatchikh
发明人： Steven LeBoeuf , Radislav Potyrailo , William Huber , Rui Chen , Todd Tolliver , Alexei Vertiatchikh
IPC分类号： H01S3/14 , H01S3/16 , H01S5/00
CPC分类号： H01S3/0959 , H01S3/16 , H01S3/169
摘要： A device for emission of electromagnetic radiation comprises a source of atomic particles and a collector disposed to receive atomic particles from the source. The collector comprises an emission medium, the medium comprising a crystal having a spatial dimension in the range from about 10 nanometers to about 50 micrometers, wherein the emission medium has the capability to generate opposing charge pairs upon absorption of atomic particles from the source and to emit electromagnetic radiation upon recombination of the pairs. The emission may be via spontaneous emission or, in certain embodiments, by stimulated emission. A laser assembly comprising this device, and methods for making the device are also presented herein.
摘要翻译：用于发射电磁辐射的装置包括原子粒子源和设置成从源极接收原子粒子的收集器。所述收集器包括发射介质，所述介质包括具有在约10纳米至约50微米范围内的空间尺寸的晶体，其中所述发射介质具有在从所述源吸收原子粒子时产生相反电荷对的能力，在配对的复合时发射电磁辐射。发射可以通过自发发射，或者在某些实施方案中，通过受激发射。包括该装置的激光组件以及用于制造该装置的方法也在本文中呈现。

3. 发明申请

US20070086915A1 Detection apparatus and associated method 有权
标题翻译：检测装置及相关方法
公开(公告)号：US20070086915A1
公开(公告)日：2007-04-19
申请号：US11480068
申请日：2006-06-30
申请人： Steven LeBoeuf , Peter Sandvik , Radislav Potyrailo
发明人： Steven LeBoeuf , Peter Sandvik , Radislav Potyrailo
IPC分类号： G01N31/22
CPC分类号： G01N33/54366 , G01N21/6428 , G01N21/645 , G01N33/54373 , G01N2021/7786
摘要： An apparatus includes an article and a detector. The article includes a substrate, a faceted structure disposed on the substrate, and a sensor layer disposed on the faceted structure. The faceted structure is disposed on the substrate first surface and itself has a surface. The faceted structure surface has peripheral edge defining a diameter of the faceted structure surface. The sensor layer is disposed on the faceted structure surface. The sensor layer can react or can interact with a target species when the target species is sufficiently proximate to the sensor layer. The sensor layer responds to the reaction or to the interaction in a detectable manner. The detector detects a response to the reaction, or to the interaction, of the target species with the sensor layer.
摘要翻译：一种装置包括物品和检测器。该物品包括基底，设置在基底上的刻面结构以及设置在刻面结构上的传感器层。小面结构设置在基板第一表面上并且本身具有表面。小面结构表面具有限定小平面结构表面直径的周缘。传感器层设置在刻面结构表面上。当目标物种足够靠近传感器层时，传感器层可以与目标物种反应或相互作用。传感器层以可检测的方式响应于反应或相互作用。检测器检测到目标物种与传感器层的反应或相互作用的响应。

4. 发明申请

US20070086916A1 Faceted structure, article, sensor device, and method 审中-公开
标题翻译：方形结构，制品，传感器装置和方法
公开(公告)号：US20070086916A1
公开(公告)日：2007-04-19
申请号：US11480185
申请日：2006-06-30
申请人： Steven LeBoeuf , Peter Sandvik , Radislav Potyrailo
发明人： Steven LeBoeuf , Peter Sandvik , Radislav Potyrailo
IPC分类号： G01N21/00
CPC分类号： G01N21/6489 , B82Y30/00 , G01N21/77
摘要： A faceted structure is provided that includes a crystalline composition comprising a metal nitride. The metal comprises one or more of aluminum, boron, indium, or gallium. The crystalline composition has at least one exposed surface that is a grain boundary, an etched surface, or a naturally formed facet, and the surface has the same crystallographic orientation of a substrate on which the crystalline composition is grown. A sensor device is provided that includes a faceted structure. Associated methods of making and using the faceted structure in a sensor device are provided.
摘要翻译：提供了一种分面结构，其包括包含金属氮化物的结晶组合物。金属包括铝，硼，铟或镓中的一种或多种。所述结晶组合物具有至少一个作为晶界，暴露的表面或天然形成的刻面的暴露表面，并且所述表面具有与其上生长所述结晶组合物的基底相同的晶体取向。提供了一种传感器装置，其包括小平面结构。提供了在传感器装置中制作和使用刻面结构的相关方法。

5. 发明授权

US08587410B2 System and method for operating RFID devices 有权
标题翻译：操作RFID设备的系统和方法
公开(公告)号：US08587410B2
公开(公告)日：2013-11-19
申请号：US13145172
申请日：2010-01-28
申请人： Radislav Potyrailo , Vincent F. Pizzi , Hanno Ehring , Cheryl M. Surman , Klaus Gebauer , Mircea Georgescu
发明人： Radislav Potyrailo , Vincent F. Pizzi , Hanno Ehring , Cheryl M. Surman , Klaus Gebauer , Mircea Georgescu
IPC分类号： G06K7/01
CPC分类号： G06K19/07749 , A61M39/10 , A61M39/18 , A61M2205/3331 , A61M2205/6054 , B65B55/08 , G06K19/07798 , G06Q20/3278
摘要： This invention provides a system for operating RFID tags on a single-use connector. The system includes: a first single-use connector configured to receive a first RFID tag and a second single-use connector configured to receive a second RFID tag. The invention also includes a reader placed close to the first RFID tag and the second RFID tag. The reader is configured to: determine if the first RFID tag and the second RFID tag are gamma sterilized; determine if the first RFID tag and the second RFID tag were previously used; determine if the first RFID tag and the second RFID tag are authentic; and determine if the first RFID tag matches with the second RFID tag.
摘要翻译：本发明提供一种用于在一次性连接器上操作RFID标签的系统。该系统包括：被配置为接收第一RFID标签的第一单用连接器和被配置为接收第二RFID标签的第二单用连接器。本发明还包括靠近第一RFID标签和第二RFID标签放置的读取器。读取器被配置为：确定第一RFID标签和第二RFID标签是否被伽马灭菌; 确定先前使用的第一RFID标签和第二RFID标签; 确定第一RFID标签和第二RFID标签是否是真实的; 并且确定第一RFID标签是否与第二RFID标签匹配。

6. 发明申请

US20070092975A1 Methods and systems for delivery of fluidic samples to sensor arrays 有权
标题翻译：将流体样品传送到传感器阵列的方法和系统
公开(公告)号：US20070092975A1
公开(公告)日：2007-04-26
申请号：US11507689
申请日：2006-08-22
申请人： Radislav Potyrailo , Prashant Shrikhande , Scott Boyette , Caibin Xiao , Andrew Leach
发明人： Radislav Potyrailo , Prashant Shrikhande , Scott Boyette , Caibin Xiao , Andrew Leach
IPC分类号： G01N21/77
CPC分类号： G01N21/78 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L2200/0605 , B01L2200/0642 , B01L2300/0806 , B01L2300/0816 , B01L2300/0864 , B01L2300/087 , B01L2400/0406 , B01L2400/0427 , B01L2400/0448 , G01N21/80 , G01N35/00069 , G01N2021/7766 , G01N2021/7773 , G01N2021/7783 , G01N2021/7786 , G01N2021/7793 , Y10T436/144444 , Y10T436/25 , Y10T436/2575
摘要： Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Delivery means are provided to deliver a metered quantity of sample fluid to the sensor array. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.
摘要翻译：公开了用于在水和/或其它工艺系统中同时监测一套生物和/或化学物质的总分析系统和方法。该系统提供了一个样品量控制的传感器阵列，其包括流体输送装置和多个光学传感器元件，用于同时确定过程系统中多个分析物的存在和总浓度。提供输送装置以将计量的样品流体传送到传感器阵列。提供图像识别算法，用于基于图像强度，颜色图案，位置排列等来识别分析物。该方法结合了多变量优化算法来分析多个传感器响应。这产生的分析结果通常难以在没有完整系统或可变补偿的情况下获得。然后可以使用改进的阵列响应来测量，监测和控制化学或生物样品或水系统中分析物的浓度。

7. 发明申请

US20070092407A1 Optical sensor array system and method for parallel processing of chemical and biochemical information 有权
标题翻译：光学传感器阵列系统和化学和生化信息并行处理方法
公开(公告)号：US20070092407A1
公开(公告)日：2007-04-26
申请号：US11259643
申请日：2005-10-26
申请人： Caibin Xiao , Radislav Potyrailo , William Morris , Scott Boyette , LiJie Yu , Theodore Cecconie , Andrew Leach , Prashant Shrikhande
发明人： Caibin Xiao , Radislav Potyrailo , William Morris , Scott Boyette , LiJie Yu , Theodore Cecconie , Andrew Leach , Prashant Shrikhande
IPC分类号： G01N21/29 , G01N21/41
CPC分类号： G01N21/78 , B01L3/50273 , B01L3/502746 , B01L2200/0621 , B01L2300/0803 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/088 , G01N21/253 , G01N21/80 , G01N31/22 , Y10T137/7036
摘要： Total analysis systems and methods for simultaneously monitoring a suite of biological and/or chemical species in water and/or other process systems are disclosed. The system provides a sample-volume controlled sensor array comprising a fluid delivery device and a plurality of optical sensor elements for determining the presence and total concentrations of multiple analytes in the process system simultaneously. Image identification algorithms are provided for identifying the analytes based on image intensity, color pattern, positional arrangement, and the like. The methods incorporate multivariate optimization algorithms to analyze multiple sensor responses. This produces analytical results that are typically difficult to obtain without full system or variable compensation. The improved array response may then be utilized to measure, monitor, and control the concentration of analytes in the chemical or biological sample or water system.
摘要翻译：公开了用于在水和/或其它工艺系统中同时监测一套生物和/或化学物质的总分析系统和方法。该系统提供了一个样品量控制的传感器阵列，其包括流体输送装置和多个光学传感器元件，用于同时确定过程系统中多个分析物的存在和总浓度。提供图像识别算法，用于基于图像强度，颜色图案，位置排列等来识别分析物。该方法结合了多变量优化算法来分析多个传感器响应。这产生的分析结果通常难以在没有完整系统或可变补偿的情况下获得。然后可以利用改进的阵列响应来测量，监测和控制化学或生物样品或水系统中分析物的浓度。

8. 发明申请

US20060210440A1 Opto-acoustic sensor system and associated method 审中-公开
标题翻译：光声传感器系统及相关方法
公开(公告)号：US20060210440A1
公开(公告)日：2006-09-21
申请号：US11391743
申请日：2006-03-29
申请人： Radislav Potyrailo , Timothy Sivavec , Joseph Salvo
发明人： Radislav Potyrailo , Timothy Sivavec , Joseph Salvo
IPC分类号： G01N27/00
CPC分类号： G01N21/7703 , G01N21/1702
摘要： A system that includes a device is provided in which the device includes a piezoelectric substrate; a sensor layer disposed on the substrate and operable to interact with, or react with, a target species; a first and a second electrode that are spaced from each other and in communication with the substrate; a first detector operable to detect the interaction or the reaction of the sensor layer with the target species based on a change in an optical characteristic of electromagnetic radiation propagated through the substrate; and a second detector operable to acoustically detect the interaction or the reaction of the sensor layer with the target species. Associated methods are provided.
摘要翻译：提供一种包括装置的系统，其中所述装置包括压电基板; 传感器层，其设置在所述基板上并且可操作以与目标物种相互作用或与目标物质反应; 第一和第二电极，彼此间隔开并与衬底连通; 第一检测器，其可操作以基于传播通过所述衬底的电磁辐射的光学特性的变化来检测所述传感器层与所述目标物质的相互作用或反应; 以及第二检测器，其可操作以声学地检测传感器层与目标物种的相互作用或反应。提供相关方法。

9. 发明申请

US20060138079A1 Fabrication process of microfluidic devices 审中-公开
标题翻译：微流体装置的制造工艺
公开(公告)号：US20060138079A1
公开(公告)日：2006-06-29
申请号：US11021399
申请日：2004-12-27
申请人： Radislav Potyrailo , Scott Boyette , Canan Hardwicke , Andrew Leach
发明人： Radislav Potyrailo , Scott Boyette , Canan Hardwicke , Andrew Leach
IPC分类号： B23P15/00 , B29C33/40 , B05D1/36 , B29C35/08
CPC分类号： B29C35/0894 , B01J2219/00286 , B01J2219/00378 , B01J2219/00387 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00657 , B01J2219/00659 , B01L3/5027 , B29L2031/756
摘要： A method for making a microfluidic device comprises providing a processing substrate, forming a negative stamp on the processing substrate using a direct write process, disposing a coating material on the processing substrate, curing the coating material to produce a cured coating material, and separating the processing substrate and the negative stamp from the cured coating material, wherein a plurality of channels are formed in the cured coating material corresponding to a location of the negative stamp.
摘要翻译：一种制造微流体装置的方法包括：提供处理基板，使用直接写入工艺在处理基板上形成负印模，在处理基板上设置涂层材料，固化涂层材料以产生固化涂层材料，处理基板和来自固化涂层材料的负印模，其中在对应于负印模的位置的固化涂层材料中形成多个通道。

10. 发明申请

US20060033325A1 Authenticatable article and method of authenticating 失效
公开(公告)号：US20060033325A1
公开(公告)日：2006-02-16
申请号：US10889913
申请日：2004-07-13
申请人： Sriramakrishna Maruvada , Radislav Potyrailo , Philippe Schottland
发明人： Sriramakrishna Maruvada , Radislav Potyrailo , Philippe Schottland
IPC分类号： B32B3/02 , B42D15/00 , B32B5/16
CPC分类号： G11B23/281 , Y10S428/913 , Y10S428/916 , Y10S428/917 , Y10T428/2982 , Y10T428/31507 , Y10T428/31663 , Y10T436/13
摘要： An authenticatable article can comprise a polymer layer comprising a first taggant, and a second taggant disposed adjacent to the first taggant. The relative relationship of the first taggant and the second taggant can be such that at least one of the first taggant and the second taggant can cause an alteration in an emission from the other of the first taggant and the second taggant. One method of authenticating an article comprises illuminating an article and determining if an altered emission is within a selected emission range. The article comprises a polymer layer and a coating disposed on a side of the polymer layer. The polymer layer comprises a first taggant, and the coating causes a predetermined alteration in an emission from the taggant to form the altered emission.

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