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1. 发明授权

US09133051B2 Cooling shroud for a post-manufacture glass container thermal strengthening station 有权
标题翻译：后制玻璃容器热加固站的冷却罩
公开(公告)号：US09133051B2
公开(公告)日：2015-09-15
申请号：US13114744
申请日：2011-05-24
申请人： Steven J. Brown , Jarmo Kammonen , Kenneth L. Bratton , Timothy A. Ringuette , Pierre S. Lankeu Ngankeu
发明人： Steven J. Brown , Jarmo Kammonen , Kenneth L. Bratton , Timothy A. Ringuette , Pierre S. Lankeu Ngankeu
IPC分类号： C03B27/00 , C03B27/06
CPC分类号： C03B27/062 , C03B27/06
摘要： An apparatus for manufacturing strengthened glass containers, and more particularly the construction and operation of a cooling shroud in an apparatus for thermally strengthening glass containers in a glass container manufacturing line at a location intermediate the hot end and the cold end. Glass containers formed at an I. S. machine are conveyed through a special tempering Lehr that heats them uniformly to a high temperature that is short of temperatures at which they may become deformed. Subsequently, the glass containers are rapidly thermally strengthened in a cooling station in which the outer and inner surfaces including all areas of the glass containers are simultaneously cooled to a temperature below the Strain Point of the glass used in the glass containers, with the cooling shrouds being used to cool the outer surfaces of the glass containers.
摘要翻译：更具体地，涉及一种用于在玻璃容器生产线中的玻璃容器生产线中的热端和冷端之间的位置处对玻璃容器进行热强化的设备中的冷却护罩的构造和操作。在I.S机上形成的玻璃容器通过特殊的回火Lehr进行输送，将其均匀加热至低于可能变形的温度的高温。随后，在包括玻璃容器的所有区域的外表面和内表面被同时冷却到低于玻璃容器中使用的玻璃的应变点的温度的冷却站中，玻璃容器被快速热增强，其中冷却罩用于冷却玻璃容器的外表面。

2. 发明授权

US08857218B2 Cooling tube nozzle for a post-manufacture glass container thermal strengthening station 有权
标题翻译：用于后制玻璃容器热加强站的冷却管喷嘴
公开(公告)号：US08857218B2
公开(公告)日：2014-10-14
申请号：US13114688
申请日：2011-05-24
申请人： Steven J. Brown , Kenneth L. Bratton , Pierre S. Lankeu Ngankeu , Paul Stargardter
发明人： Steven J. Brown , Kenneth L. Bratton , Pierre S. Lankeu Ngankeu , Paul Stargardter
IPC分类号： C03B27/06
CPC分类号： C03B27/062
摘要： An apparatus for manufacturing strengthened glass containers, and more particularly the construction and operation of a cooling tube nozzle in an apparatus for thermally strengthening glass containers in a glass container manufacturing line at a location intermediate the hot end and the cold end. Glass containers formed at an I. S. machine are conveyed through a special tempering Lehr that heats them uniformly to a high temperature that is short of temperatures at which they may become deformed. Subsequently, the glass containers are rapidly thermally strengthened in a cooling station in which the outer and inner surfaces including all areas of the glass containers are simultaneously cooled to a temperature below the Strain Point of the glass used in the glass containers, with the cooling tube nozzles being used to cool the inner surfaces of the glass containers.
摘要翻译：更具体地，涉及一种用于在玻璃容器生产线中热玻璃容器生产线中的热端和冷端中间位置处的加热玻璃容器的设备中的冷却管喷嘴的结构和操作。在I.S机上形成的玻璃容器通过特殊的回火Lehr进行输送，将其均匀加热至低于可能变形的温度的高温。随后，在包括玻璃容器的所有区域的外表面和内表面被同时冷却到低于玻璃容器中使用的玻璃的应变点的温度的冷却站中，玻璃容器被快速热增强，冷却管喷嘴用于冷却玻璃容器的内表面。

3. 发明授权

US08656742B2 Bottom cooler for a post-manufacture glass container thermal strengthening station 有权
标题翻译：后冷却器用于后制玻璃容器热加固站
公开(公告)号：US08656742B2
公开(公告)日：2014-02-25
申请号：US13114779
申请日：2011-05-24
申请人： Robert J. Lockhart , Steven J. Brown , Timothy A. Ringuette
发明人： Robert J. Lockhart , Steven J. Brown , Timothy A. Ringuette
IPC分类号： C03B27/06
CPC分类号： C03B27/062 , C03B27/06 , C03B27/065
摘要： An apparatus for manufacturing strengthened glass containers, and more particularly the construction and operation of a bottom cooler in an apparatus for thermally strengthening glass containers in a glass container manufacturing line at a location intermediate the hot end and the cold end. Glass containers formed at an I.S. machine are conveyed through a special tempering Lehr that heats them uniformly to a high temperature that is short of temperatures at which they may become deformed. Subsequently, the glass containers are rapidly thermally strengthened in a cooling station in which the outer and inner surfaces including all areas of the glass containers are simultaneously cooled to a temperature below the Strain Point of the glass used in the glass containers, with the bottom coolers being used to cool the bottoms of the glass containers.
摘要翻译：更具体地，涉及用于在玻璃容器生产线中热玻璃容器生产线中的热端和冷端之间的位置热加强的装置中底部冷却器的制造和操作的装置。在美国制造的玻璃容器机器通过特殊的回火Lehr被输送，将它们均匀地加热到低于它们可能变形的温度的高温。随后，在包括玻璃容器的所有区域的外表面和内表面被同时冷却到低于玻璃容器中使用的玻璃的应变点的温度的冷却站中，玻璃容器被快速热强化，底部冷却器用于冷却玻璃容器的底部。

4. 发明申请

US20110289976A1 Base Cooling Nozzle for a Post-Manufacture Glass Container Thermal Strengthening Station 有权
标题翻译：用于后制玻璃容器热加固站的底座冷却喷嘴
公开(公告)号：US20110289976A1
公开(公告)日：2011-12-01
申请号：US13114765
申请日：2011-05-24
申请人： Steven J. Brown
发明人： Steven J. Brown
IPC分类号： C03B27/06 , C03B27/00
CPC分类号： C03B27/062 , C03B27/06
摘要： An apparatus for manufacturing strengthened glass containers, and more particularly the construction and operation of a base cooling nozzle in an apparatus for thermally strengthening glass containers in a glass container manufacturing line at a location intermediate the hot end and the cold end. Glass containers formed at an I.S. machine are conveyed through a special tempering Lehr that heats them uniformly to a high temperature that is short of temperatures at which they may become deformed. Subsequently, the glass containers are rapidly thermally strengthened in a cooling station in which the outer and inner surfaces including all areas of the glass containers are simultaneously cooled to a temperature below the Strain Point of the glass used in the glass containers, with the base cooling nozzles being used to cool the bottoms of the glass containers.
摘要翻译：特别是用于在玻璃容器生产线中的玻璃容器生产线中的热端和冷端之间的位置处对玻璃容器进行热强化的装置中的基座冷却喷嘴的结构和操作的装置。在美国制造的玻璃容器机器通过特殊的回火Lehr被输送，将它们均匀地加热到低于它们可能变形的温度的高温。随后，在包括玻璃容器的所有区域的外表面和内表面被同时冷却到低于玻璃容器中使用的玻璃的应变点的温度的冷却站中，玻璃容器被快速热强化，基底冷却喷嘴用于冷却玻璃容器的底部。

5. 发明授权

US6092283A Method and apparatus for producing a gear pump 失效
标题翻译：齿轮泵的制造方法及装置
公开(公告)号：US6092283A
公开(公告)日：2000-07-25
申请号：US544909
申请日：1995-10-18
申请人： Steven J. Brown , Vijay P. Shah
发明人： Steven J. Brown , Vijay P. Shah
IPC分类号： F04C2/18 , F04C2/08 , F04C15/00 , B23P15/00
CPC分类号： F04C15/0049 , F04C2/086 , Y10T29/49242 , Y10T29/4984 , Y10T29/49995 , Y10T29/49996
摘要： A method is provided for producing a gear pump/motor in a low cost and efficient manner that can effectively operate in air entrained oil without emitting undesirable noises. This is accomplished by providing bleed slots in a housing adjacent an outlet passage at a location that allows first and second intersecting cavities to be machined with the same boring tool. The bleed slots have a length defined by the distance between two adjacent teeth of first and second intermeshing gears and a cross-sectional area at the mid-point of the arcuate length that is defined by multiplying the flow of the pump at a given RPM time a derived constant. The machining of the body of the gear pump/motor is accomplished in a low cost and efficient manner to produce a gear pump/motor that operates in air entrained oil without emitting undesirable noises.
摘要翻译：提供一种用于以低成本和有效的方式生产齿轮泵/马达的方法，其可以有效地在夹带的空气中操作，而不会发出不期望的噪声。这通过在允许第一和第二相交空腔用相同的钻孔工具加工的位置处在邻近出口通道的壳体中提供排放槽来实现。排放槽具有由第一和第二啮合齿轮的两个相邻齿之间的距离限定的长度和在弓形长度的中点处的横截面积，其通过在给定的RPM时间乘以泵的流量来限定派生常数。齿轮泵/马达的主体的加工以低成本和有效的方式实现，以生产在空气夹带的油中运行的齿轮泵/马达，而不会发出不期望的噪音。

6. 发明申请

US20110289977A1 Post-Manufacture Glass Container Thermal Strengthening Station 有权
标题翻译：后制玻璃容器热加固站
公开(公告)号：US20110289977A1
公开(公告)日：2011-12-01
申请号：US13114649
申请日：2011-05-24
申请人： Timothy A. Ringuette , Steven J. Brown , Kenneth L. Bratton
发明人： Timothy A. Ringuette , Steven J. Brown , Kenneth L. Bratton
IPC分类号： C03B27/06 , C03B35/04 , C03B27/00
CPC分类号： C03B27/062
摘要： An apparatus for manufacturing strengthened glass containers, and more particularly an apparatus for thermally strengthening glass containers in a glass container manufacturing line at a location intermediate the hot end and the cold end. Glass containers formed at an I. S. machine are conveyed through a special tempering Lehr that heats them uniformly to a high temperature that is short of temperatures at which they may become deformed. Subsequently, the glass containers are rapidly thermally strengthened in a cooling station in which the outer and inner surfaces including all areas of the glass containers are simultaneously cooled to a temperature below the Strain Point of the glass used in the glass containers.
摘要翻译：一种用于制造强化玻璃容器的装置，更具体地说，一种用于在玻璃容器生产线中的热端和冷端之间的位置处对玻璃容器进行热强化的装置。在I.S机上形成的玻璃容器通过特殊的回火Lehr进行输送，将其均匀加热至低于可能变形的温度的高温。随后，在包括玻璃容器的所有区域的外表面和内表面被同时冷却到低于玻璃容器中使用的玻璃的应变点的温度的冷却站中，玻璃容器被快速热强化。

7. 发明申请

US20110289975A1 Cooling Shroud for a Post-Manufacture Glass Container Thermal Strengthening Station 有权
标题翻译：后制玻璃容器热加固站的冷却罩
公开(公告)号：US20110289975A1
公开(公告)日：2011-12-01
申请号：US13114744
申请日：2011-05-24
申请人： Steven J. Brown , Jarmo Kammonen , Kenneth L. Bratton , Timothy A. Ringuette , Pierre S. Lankeu Ngankeu
发明人： Steven J. Brown , Jarmo Kammonen , Kenneth L. Bratton , Timothy A. Ringuette , Pierre S. Lankeu Ngankeu
IPC分类号： C03B27/06 , C03B27/00
CPC分类号： C03B27/062 , C03B27/06
摘要： An apparatus for manufacturing strengthened glass containers, and more particularly the construction and operation of a cooling shroud in an apparatus for thermally strengthening glass containers in a glass container manufacturing line at a location intermediate the hot end and the cold end. Glass containers formed at an I. S. machine are conveyed through a special tempering Lehr that heats them uniformly to a high temperature that is short of temperatures at which they may become deformed. Subsequently, the glass containers are rapidly thermally strengthened in a cooling station in which the outer and inner surfaces including all areas of the glass containers are simultaneously cooled to a temperature below the Strain Point of the glass used in the glass containers, with the cooling shrouds being used to cool the outer surfaces of the glass containers.
摘要翻译：更具体地，涉及一种用于在玻璃容器生产线中的玻璃容器生产线中的热端和冷端之间的位置处对玻璃容器进行热强化的设备中的冷却护罩的构造和操作。在I.S机上形成的玻璃容器通过特殊的回火Lehr进行输送，将其均匀加热至低于可能变形的温度的高温。随后，在包括玻璃容器的所有区域的外表面和内表面被同时冷却到低于玻璃容器中使用的玻璃的应变点的温度的冷却站中，玻璃容器被快速热增强，其中冷却罩用于冷却玻璃容器的外表面。

8. 发明申请

US20090253717A1 Inhibitors of p97 有权
标题翻译： p97的抑制剂
公开(公告)号：US20090253717A1
公开(公告)日：2009-10-08
申请号：US12321463
申请日：2009-01-20
申请人： Steven J. Brown , Tsui-Fen Chou , Raymond Deshaies , Amanda C. Jones , Hugh Rosen , Brian M. Stoltz
发明人： Steven J. Brown , Tsui-Fen Chou , Raymond Deshaies , Amanda C. Jones , Hugh Rosen , Brian M. Stoltz
IPC分类号： A61K31/519 , A61P35/00
CPC分类号： A61K31/519
摘要： One aspect of the invention relates to compounds that inhibit the activity of p97, such as by binding covalently to a cysteine residue in the active site. In certain embodiments, the invention relates to the treatment of disease, such as cancer, comprising administering a compound of the invention.
摘要翻译：本发明的一个方面涉及抑制p97活性的化合物，例如通过与活性位点中的半胱氨酸残基共价结合。在某些实施方案中，本发明涉及疾病如癌症的治疗，其包括施用本发明的化合物。

9. 发明授权

US06386000B1 I.S. machine 有权
标题翻译：美国机
公开(公告)号：US06386000B1
公开(公告)日：2002-05-14
申请号：US09460582
申请日：1999-12-14
申请人： Frank Alan Fenton , Steven J. Brown
发明人： Frank Alan Fenton , Steven J. Brown
IPC分类号： C03B9353
CPC分类号： C03B9/3537
摘要： An I.S. machine is disclosed which has at least one section having a mold station wherein a glass forming operation is performed within a mold which includes an opposed pair of mold halves each of which has a blank diameter which can vary within a selected range and a planar surface to be clampingly engaged with the planar surface of the other mold half at a mold centerline. The section has a mold open and closed mechanism which includes a pair of opposed displaceable mold holders for holding one or a plurality of opposed pairs of mold halves, and a drive assembly for displacing the mold holders from a selected open position, the location of which is a direct function of the dimension of the blank diameter of the mold halves supported on the mold holders, to a closed position.
摘要翻译：美国机器被公开，其具有至少一个具有模具台的部分，其中在模具内执行玻璃成型操作，该模具包括相对的一对半模，每个半模具有在选定范围内变化的坯料直径，并且平面表面与在模具中心线处与另一半模的平坦表面夹紧接合。该部分具有模具打开和关闭机构，其包括一对相对的可移动模具保持器，用于保持一个或多个相对的一对半模;以及驱动组件，用于将模具夹持器从选定的打开位置移位，其位置是支撑在模具架上的半模的坯料直径的尺寸的直接函数，到关闭位置。

10. 发明授权

US5705334A Uses for DNA structure-specific recognition protein 失效
公开(公告)号：US5705334A
公开(公告)日：1998-01-06
申请号：US328809
申请日：1994-10-25
申请人： Stephen J. Lippard , John M. Essigmann , Brian Donahue , Jeffrey H. Toney , Suzanne L. Bruhn , Pieter M. Pil , Steven J. Brown , Patti J. Kellett
发明人： Stephen J. Lippard , John M. Essigmann , Brian Donahue , Jeffrey H. Toney , Suzanne L. Bruhn , Pieter M. Pil , Steven J. Brown , Patti J. Kellett
IPC分类号： A61K38/00 , C07K14/435 , C07K14/47 , C07K16/18 , C12Q1/68 , C12N15/00
CPC分类号： C07K14/435 , C07K14/43581 , C07K14/47 , C07K16/18 , C12Q1/68 , C12Q1/6876 , C12Q1/6883 , A61K38/00 , C12Q2600/142
摘要： Methods disclosed herein capitalize on the ability of DNA Structure Specific Recognition Proteins (SSRPs) to bind to genomic lesions formed by chemotherapeutic agents, particularly cisplatin-type agents. Methods are provided for predicting whether an agent that damages DNA will also be cytotoxic, and for predicting whether particular eukaryotic cells will be susceptible to killing by a genotoxic drug. A screening method is provided for identifying new genotoxic drugs that produce SSRP-recognized lesions in DNA. Methods also are provided for sensitizing particular eukaryotic cells to killing by chemotherapeutic agents, particularly cisplatin-type drugs.

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