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1. 发明申请

US20100262556A1 INTELLIGENT PERFORMANCE-BASED PRODUCT RECOMMENDATION 有权
标题翻译：智能性能产品推荐
公开(公告)号：US20100262556A1
公开(公告)日：2010-10-14
申请号：US12820844
申请日：2010-06-22
申请人： Steven A. Shaya , Neal Matheson , John Anthony Singarayar , Nikiforos Kollias , Jeffrey Adam Bloom
发明人： Steven A. Shaya , Neal Matheson , John Anthony Singarayar , Nikiforos Kollias , Jeffrey Adam Bloom
IPC分类号： G06Q99/00 , G06N5/02
CPC分类号： G06Q30/0631 , G06Q30/02 , G06Q30/0202 , G06Q30/0254 , G06Q30/0282 , G06Q30/0641
摘要： Systems and methods of utilizing communications networks and multivariate analysis to predict or recommend optimal products from a predefined population of commercially available products are disclosed. The recommendations are based on intelligence contained in processing elements and subjective and/or objective product information received from consumers or input to the systems as part of their initial setup. The output of the systems comprise sets of products that they predict the consumer will prefer and/or perform well for the problem or concern identified by the consumer. The performance and preference predictions are a function of consumer problems and product responsiveness patterns. Objective product information is generally obtained with diagnostic instruments. Data measured with the diagnostic instruments may be communicated to the data processing portions of the invention via the Internet. The outputs of the data processing portion of the system may be presented to consumers via the Internet as well.
摘要翻译：公开了利用通信网络和多变量分析来预测或推荐来自预定义的市售产品群体的最佳产品的系统和方法。这些建议是基于处理要素中包含的智能，以及从消费者收到的主观和/或客观的产品信息，或作为其初始设置的一部分输入到系统。系统的输出包括他们预测消费者将更喜欢和/或对于消费者所识别的问题或关切而表现良好的产品集合。性能和偏好预测是消费者问题和产品响应模式的函数。客观的产品信息通常用诊断仪器获得。用诊断仪器测量的数据可以经由因特网传送到本发明的数据处理部分。系统的数据处理部分的输出也可以经由因特网向消费者呈现。

2. 发明授权

US07809601B2 Intelligent performance-based product recommendation system 有权
标题翻译：智能性能型产品推荐系统
公开(公告)号：US07809601B2
公开(公告)日：2010-10-05
申请号：US09981516
申请日：2001-10-17
申请人： Steven A. Shaya , Neal Matheson , John Anthony Singarayar , Nikiforos Kollias , Jeffrey Adam Bloom
发明人： Steven A. Shaya , Neal Matheson , John Anthony Singarayar , Nikiforos Kollias , Jeffrey Adam Bloom
IPC分类号： G06F17/30
CPC分类号： G06Q30/0631 , G06Q30/02 , G06Q30/0202 , G06Q30/0254 , G06Q30/0282 , G06Q30/0641
摘要： Systems and methods of utilizing communications networks and multivariate analysis to predict or recommend optimal products from a predefined population of commercially available products are disclosed. The recommendations are based on intelligence contained in processing elements and subjective and/or objective product information received from consumers or input to the systems as part of their initial setup. The output of the systems comprise sets of products that they predict the consumer will prefer and/or perform well for the problem or concern identified by the consumer. The performance and preference predictions are a function of consumer problems and product responsiveness patterns. Objective product information is generally obtained with diagnostic instruments. Data measured with the diagnostic instruments may be communicated to the data processing portions of the invention via the Internet. The outputs of the data processing portion of the system may be presented to consumers via the Internet as well.
摘要翻译：公开了利用通信网络和多变量分析来预测或推荐来自预定义的市售产品群体的最佳产品的系统和方法。这些建议是基于处理要素中包含的智能，以及从消费者收到的主观和/或客观的产品信息，或作为其初始设置的一部分输入到系统。系统的输出包括他们预测消费者将更喜欢和/或对于消费者所识别的问题或关切而表现良好的产品集合。性能和偏好预测是消费者问题和产品响应模式的函数。客观的产品信息通常用诊断仪器获得。用诊断仪器测量的数据可以经由因特网传送到本发明的数据处理部分。系统的数据处理部分的输出也可以经由因特网向消费者呈现。

3. 发明授权

US08666844B2 Intelligent performance-based product recommendation system 有权
标题翻译：智能性能型产品推荐系统
公开(公告)号：US08666844B2
公开(公告)日：2014-03-04
申请号：US12820844
申请日：2010-06-22
申请人： Steven A. Shaya , Neal Matheson , John Anthony Singarayar , Nikiforos Kollias , Jeffrey Adam Bloom
发明人： Steven A. Shaya , Neal Matheson , John Anthony Singarayar , Nikiforos Kollias , Jeffrey Adam Bloom
IPC分类号： G06Q30/00
CPC分类号： G06Q30/0631 , G06Q30/02 , G06Q30/0202 , G06Q30/0254 , G06Q30/0282 , G06Q30/0641
摘要： Systems and methods of utilizing communications networks and multivariate analysis to predict or recommend optimal products from a predefined population of commercially available products are disclosed. The recommendations are based on intelligence contained in processing elements and subjective and/or objective product information received from consumers or input to the systems as part of their initial setup. The output of the systems comprise sets of products that they predict the consumer will prefer and/or perform well for the problem or concern identified by the consumer. The performance and preference predictions are a function of consumer problems and product responsiveness patterns. Objective product information is generally obtained with diagnostic instruments. Data measured with the diagnostic instruments may be communicated to the data processing portions of the invention via the Internet. The outputs of the data processing portion of the system may be presented to consumers via the Internet as well.
摘要翻译：公开了利用通信网络和多变量分析来预测或推荐来自预定义的市售产品群体的最佳产品的系统和方法。这些建议是基于处理要素中包含的智能，以及从消费者收到的主观和/或客观的产品信息，或作为其初始设置的一部分输入到系统。系统的输出包括他们预测消费者将更喜欢和/或对于消费者所识别的问题或关切而表现良好的产品集合。性能和偏好预测是消费者问题和产品响应模式的函数。客观的产品信息通常用诊断仪器获得。用诊断仪器测量的数据可以经由因特网传送到本发明的数据处理部分。系统的数据处理部分的输出也可以经由因特网向消费者呈现。

4. 发明申请

US20120053429A1 Non-Invasive Tissue Glucose-Level Monitoring 审中-公开
标题翻译：非侵入性组织葡萄糖水平监测
公开(公告)号：US20120053429A1
公开(公告)日：2012-03-01
申请号：US13037348
申请日：2011-02-28
申请人： Pierre Trepagnier , Jenny Freeman , James Mansfield , Derek Brand , Michael J. Hopmeier , Nikiforos Kollias
发明人： Pierre Trepagnier , Jenny Freeman , James Mansfield , Derek Brand , Michael J. Hopmeier , Nikiforos Kollias
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/0071 , A61B5/14532
摘要： A non-invasive analyte monitoring instrument has a radiation source for directing excitation radiation to a portion of a surface of a tissue wherein said source emits radiation at a plurality of different wavelengths that excites a target in said tissue causing said target to emit radiation such that the radiation received at the surface provides an analyte level indication of the patient. A radiation detector positioned to receive radiation emitted from the surface wherein said radiation detector is configured to synchronously scan radiation emitted by the target with the excitation radiation. A processing circuit operatively connected to the radiation detector that translates radiation received at the surface to a measurable signal to obtain said analyte level indication, wherein said radiation source comprises a visible light source or an ultraviolet light source and wherein the target is selected from the group consisting of a structural matrix tissue component, a cellular tissue component, a mitochondrial tissue component, a collagen cross link, a pepsin-digestible collagen cross link, a collagenase-digestible collagen cross link, a non-pepsin digestible collagen cross link, an elastin cross link, a tryptophan-containing protein, NADH, FAD, a flavoprotein, and any combination thereof.
摘要翻译：非侵入性分析物监测仪器具有用于将激发辐射引导到组织表面的一部分的辐射源，其中所述源以多个不同波长发射辐射，激发所述组织中的靶，使所述靶发射辐射，使得在表面处接收的辐射提供了患者的分析物水平指示。放射线检测器，定位成接收从表面发射的辐射，其中所述辐射检测器被配置成以激发辐射同步扫描由靶发射的辐射。一种可操作地连接到辐射检测器的处理电路，其将在表面处接收的辐射转换成可测量信号，以获得所述分析物水平指示，其中所述辐射源包括可见光源或紫外光源，并且其中所述靶选自组由结构基质组织成分，细胞组织成分，线粒体组织成分，胶原交联，胃蛋白酶消化型胶原交联，胶原酶消化型胶原交联，非胃蛋白酶消化型胶原交联，弹性蛋白交联，含色氨酸的蛋白质，NADH，FAD，黄素蛋白及其任何组合。

5. 发明授权

US07899518B2 Non-invasive tissue glucose level monitoring 失效
标题翻译：非侵入性组织葡萄糖水平监测
公开(公告)号：US07899518B2
公开(公告)日：2011-03-01
申请号：US11224690
申请日：2005-09-12
申请人： Pierre Trepagnier , Jenny Freeman , James Mansfield , Derek Brand , Michael J. Hopmeier , Nikiforos Kollias
发明人： Pierre Trepagnier , Jenny Freeman , James Mansfield , Derek Brand , Michael J. Hopmeier , Nikiforos Kollias
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/0071 , A61B5/14532
摘要： Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.
摘要翻译：描述了用于对分析物水平进行非侵入性测量并用于监测，分析和调节组织状态（例如组织葡萄糖水平）的仪器和方法。

6. 发明授权

US07738032B2 Apparatus for and method of taking and viewing images of the skin 有权
标题翻译：用于拍摄和观看皮肤图像的装置和方法
公开(公告)号：US07738032B2
公开(公告)日：2010-06-15
申请号：US10978284
申请日：2004-10-29
申请人： Nikiforos Kollias , Kenneth Merola , Jeffrey S. Pote , Gregory Payonk
发明人： Nikiforos Kollias , Kenneth Merola , Jeffrey S. Pote , Gregory Payonk
IPC分类号： H04N5/222 , H04N5/225 , A61B1/04 , A61B6/00
CPC分类号： G03B29/00 , A61B5/0071 , A61B5/441 , G06F19/00
摘要： A self-contained, portable apparatus and corresponding method for capturing, displaying and analyzing images of a person includes a housing for containing a digital camera, a light source capable of providing at least two different wavelengths of light, a touch-screen display and a computer for controlling the camera, the light source and the display. The apparatus selectively captures and displays a plurality of digital images using different wavelengths of illuminating light. The light source may include a plurality of flashes and filters, some of which may be adjustable to adjust the angle of incidence of the illuminating light on the subject. Preferably, the apparatus is self-serve, allowing any person to capture, review and analyze the images. To that end, the apparatus may provide a moving image and verbal instructions to a user to aid in positioning themselves relative to the camera. Instruction may further be provided by text or internet connection for using the apparatus and/or interpreting the captured images. An intuitive graphic user interface with thumbnail images is employed. Focus control, zoom and synchronized side-by side comparison of images are available.
摘要翻译：用于捕获，显示和分析人的图像的独立的便携式设备和相应的方法包括用于容纳数字照相机的外壳，能够提供至少两种不同波长的光的光源，触摸屏显示器和用于控制摄像机，光源和显示器的计算机。该装置选择性地捕获和显示使用不同波长的照明光的多个数字图像。光源可以包括多个闪光和滤光器，其中一些可以是可调节的，以调节被摄体上的照明光的入射角。优选地，该装置是自助服务的，允许任何人捕获，查看和分析图像。为此，设备可以向用户提供运动图像和口头指令，以帮助相对于照相机自己定位。可以通过文本或因特网连接进一步提供使用该设备和/或解释所捕获的图像的指令。使用具有缩略图的直观的图形用户界面。焦点控制，缩放和同步并排比较图像可用。

7. 发明授权

US07376346B2 Method of promoting skin care products 有权
标题翻译：促进护肤品的方法
公开(公告)号：US07376346B2
公开(公告)日：2008-05-20
申请号：US11125627
申请日：2005-05-10
申请人： Kenneth Merola , Nikiforos Kollias , Jeffrey S. Pote , Gregory Payonk
发明人： Kenneth Merola , Nikiforos Kollias , Jeffrey S. Pote , Gregory Payonk
IPC分类号： G03B41/00 , G01J4/00
CPC分类号： G09F5/00 , A61B5/0071 , G03B1/00 , G03B15/00 , G03B29/00
摘要： The present invention relates to a method of assessing the efficacy of skin care products by comparing images of the skin prior to and after use of said skin care product.
摘要翻译：本发明涉及一种通过比较使用所述皮肤护理产品之前和之后的皮肤图像来评估护肤产品的功效的方法。

8. 发明申请

US20070238941A1 Methods and devices for evaluating skin 审中-公开
标题翻译：用于评估皮肤的方法和装置
公开(公告)号：US20070238941A1
公开(公告)日：2007-10-11
申请号：US11390760
申请日：2006-03-28
申请人： Janeta Nikolovski , Benjamin Wiegand , Georgios Stamatas , Nikiforos Kollias
发明人： Janeta Nikolovski , Benjamin Wiegand , Georgios Stamatas , Nikiforos Kollias
IPC分类号： A61B5/00
CPC分类号： A61B5/0068 , A61B5/0531 , A61B5/445
摘要： Provided are methods and devices for evaluating skin by introducing a fluid comprising water to the skin; measuring at least one skin barrier property that correlates to the water content of the skin over time, the measuring step comprising taking at least one measurement of the skin barrier property in the time frame starting from completion of the introducing step up to about 60 seconds after such introducing step and optionally taking a plurality of skin barrier property measurements after about 60 seconds after completion of the introducing step; and comparing the skin water content measurements of the measuring step with at least one Comparative Data Set to determine the relative infant-like barrier properties of the skin.
摘要翻译：提供了通过将包含水的流体引入皮肤来评价皮肤的方法和装置; 测量与皮肤随着时间的含水量相关的至少一种皮肤屏障性质，所述测量步骤包括在从引入步骤完成开始的时间范围至少大约60秒之后至少测量一次皮肤屏障性能这种引入步骤和任选地在引入步骤完成后约60秒后进行多次皮肤屏障性能测量; 以及将测量步骤的皮肤含水量测量值与至少一个比较数据组进行比较，以确定皮肤的相对婴儿样屏障性质。

9. 发明申请

US20060195022A1 Non-invasive tissue glucose level monitoring 失效
公开(公告)号：US20060195022A1
公开(公告)日：2006-08-31
申请号：US11224690
申请日：2005-09-12
申请人： Pierre Trepagnier , Jenny Freeman , James Mansfield , Derek Brand , Michael Hopmeier , Nikiforos Kollias
发明人： Pierre Trepagnier , Jenny Freeman , James Mansfield , Derek Brand , Michael Hopmeier , Nikiforos Kollias
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/0071 , A61B5/14532
摘要： Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.

10. 发明申请

US20050195316A1 Apparatus for and method of taking and viewing images of the skin 有权
标题翻译：用于拍摄和观看皮肤图像的装置和方法
公开(公告)号：US20050195316A1
公开(公告)日：2005-09-08
申请号：US10978284
申请日：2004-10-29
申请人： Nikiforos Kollias , Kenneth Merola , Jeffrey Pote , Gregory Payonk
发明人： Nikiforos Kollias , Kenneth Merola , Jeffrey Pote , Gregory Payonk
IPC分类号： G03B29/00 , H04N5/222
CPC分类号： G03B29/00 , A61B5/0071 , A61B5/441 , G06F19/00
摘要： A self-contained, portable apparatus and corresponding method for capturing, displaying and analyzing images of a person includes a housing for containing a digital camera, a light source capable of providing at least two different wavelengths of light, a touch-screen display and a computer for controlling the camera, the light source and the display. The apparatus selectively captures and displays a plurality of digital images using different wavelengths of illuminating light. The light source may include a plurality of flashes and filters, some of which may be adjustable to adjust the angle of incidence of the illuminating light on the subject. Preferably, the apparatus is self-serve, allowing any person to capture, review and analyze the images. To that end, the apparatus may provide a moving image and verbal instructions to a user to aid in positioning themselves relative to the camera. Instruction may further be provided by text or internet connection for using the apparatus and/or interpreting the captured images. An intuitive graphic user interface with thumbnail images is employed. Focus control, zoom and synchronized side-by side comparison of images are available.
摘要翻译：用于捕获，显示和分析人的图像的独立的便携式设备和相应的方法包括用于容纳数字照相机的外壳，能够提供至少两种不同波长的光的光源，触摸屏显示器和用于控制摄像机，光源和显示器的计算机。该装置选择性地捕获和显示使用不同波长的照明光的多个数字图像。光源可以包括多个闪光和滤光器，其中一些可以是可调节的，以调节被摄体上的照明光的入射角。优选地，该装置是自助服务的，允许任何人捕获，查看和分析图像。为此，设备可以向用户提供运动图像和口头指令，以帮助相对于照相机自己定位。可以通过文本或因特网连接进一步提供使用该设备和/或解释所捕获的图像的指令。使用具有缩略图的直观的图形用户界面。焦点控制，缩放和同步并排比较图像可用。

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