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1. 发明授权

US06894494B2 Method and device for correcting organ motion artifacts in MRI systems 失效
标题翻译：用于校正MRI系统中器官运动伪像的方法和装置
公开(公告)号：US06894494B2
公开(公告)日：2005-05-17
申请号：US10608141
申请日：2003-06-30
申请人： Stergios Stergiopoulos , Miroslaw Wrobel , Andreas Freibert , Waheed Younis , Amar Dhanantwari
发明人： Stergios Stergiopoulos , Miroslaw Wrobel , Andreas Freibert , Waheed Younis , Amar Dhanantwari
IPC分类号： G01R33/567 , G01V3/00
CPC分类号： G01R33/5673 , G01R33/56325
摘要： The present invention relates to a signal processing method and system for correcting organ motion artifacts for cardiac and brain imaging. A plurality of sets of MRI measurement data indicative of at least an image of an object is received. Each set corresponds to one row kx of a k-space matrix of at least a k-space matrix. For each set a k-space matrix of the at least a k-space matrix is determined for allocation thereto based on motion information of the object occurring during acquisition of the plurality of sets of the MRI measurement data. In a following step a location within the allocated k-space matrix corresponding to a row of the k-space matrix allocated thereto is determined for each set. At least a k-space matrix is then generated by re-arranging the plurality of sets. Each of the at least a k-space matrix comprises the sets of the plurality of sets of the MRI measurement data allocated thereto. Inverse Fourier transforming of the plurality of k-space matrices provides at least a reconstructed image. Through careful selection of the phases of the cardiac and respiratory cycles and corresponding ranges MRI data acquisition periods are of the order of seconds or a few minutes. Furthermore, integration of motion artifact free MRI images of different phases of organ motion using the coherent k-space synthesis according to the invention allows provision of an animation showing different phases of a cardiac or lung cycle. In an embodiment for correcting motion artifacts for brain imaging a motion vector describing translational and rotational motion of a patient's head is tracked during the MRI data acquisition process. The motion artifacts are then corrected based on coherent k-space synthesis using the motion vector data.
摘要翻译：本发明涉及用于校正心脏和脑成像的器官运动假象的信号处理方法和系统。接收指示对象的至少一个图像的多组MRI测量数据。每个集合对应于至少一个k空间矩阵的k空间矩阵的一行k×××。对于每个集合，基于在获取多组MRI测量数据的采集期间发生的对象的运动信息，确定至少k空间矩阵的k空间矩阵用于分配。在随后的步骤中，针对每个集合确定与分配给其的k空间矩阵的行相对应的所分配的k空间矩阵内的位置。然后，通过重新排列多个集合来生成至少一个k空间矩阵。所述至少k空间矩阵中的每一个包括分配给其的所述多个MRI测量数据的集合。多个k空间矩阵的逆傅立叶变换提供至少一个重构图像。通过仔细选择心脏和呼吸周期的相位和相应范围，MRI数据采集周期大约为数秒或数分钟。此外，使用根据本发明的相干k空间合成的器官运动的不同阶段的运动伪像自由MRI图像的集成允许提供显示心脏或肺循环的不同阶段的动画。在用于校正脑成像的运动伪像的实施例中，描述了在MRI数据采集过程期间描述患者头部的平移和旋转运动的运动矢量。然后基于使用运动矢量数据的相干k空间合成校正运动假象。

2. 发明申请

US20130225998A1 Dispersive Ultrasound Technology as a Diagnostic Device for Traumatic Brain Injuries 有权
标题翻译：分散超声技术作为创伤性脑损伤的诊断装置
公开(公告)号：US20130225998A1
公开(公告)日：2013-08-29
申请号：US13407378
申请日：2012-02-28
申请人： Stergios Stergiopoulos , Andreas Freibert , Jason Zhang
发明人： Stergios Stergiopoulos , Andreas Freibert , Jason Zhang
IPC分类号： A61B8/08
CPC分类号： A61B8/0808 , A61B5/4064 , A61B8/0858 , G01N2291/048
摘要： Described herein is the use of ultrasound pulses at different frequencies to track the dispersion properties of intracranial tissues which may have been altered due to traumatic or other neurological brain injury. Dispersive ultrasound does not provide imaging, but it can provide data of significant diagnostic value by using decision support systems that can be trained as a medical diagnostic system for traumatic brain injuries applications to detect specific patterns of dispersion that are associated with specific intracranial injuries.
摘要翻译：这里描述的是使用不同频率的超声波脉冲跟踪可能由于创伤性或其他神经性脑损伤而改变的颅内组织的分散性质。分散超声不提供成像，但它可以通过使用可被训练为创伤性脑损伤应用的医学诊断系统的检测支持系统来提供具有显着诊断价值的数据，以检测与特定颅内损伤相关的特定分散模式。

3. 发明授权

US08834376B2 Dispersive ultrasound technology as a diagnostic device for traumatic brain injuries 有权
标题翻译：分散超声技术作为创伤性脑损伤的诊断装置
公开(公告)号：US08834376B2
公开(公告)日：2014-09-16
申请号：US13407378
申请日：2012-02-28
申请人： Stergios Stergiopoulos , Andreas Freibert , Jason Zhang
发明人： Stergios Stergiopoulos , Andreas Freibert , Jason Zhang
IPC分类号： A61B8/00 , A61B8/08 , A61B5/00
CPC分类号： A61B8/0808 , A61B5/4064 , A61B8/0858 , G01N2291/048
摘要： Described herein is the use of ultrasound pulses at different frequencies to track the dispersion properties of intracranial tissues which may have been altered due to traumatic or other neurological brain injury. Dispersive ultrasound does not provide imaging, but it can provide data of significant diagnostic value by using decision support systems that can be trained as a medical diagnostic system for traumatic brain injuries applications to detect specific patterns of dispersion that are associated with specific intracranial injuries.
摘要翻译：这里描述的是使用不同频率的超声波脉冲跟踪可能由于创伤性或其他神经性脑损伤而改变的颅内组织的分散性质。分散超声不提供成像，但它可以通过使用可被训练为创伤性脑损伤应用的医学诊断系统的检测支持系统来提供具有显着诊断价值的数据，以检测与特定颅内损伤相关的特定分散模式。

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