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1. 外观设计

USD985695S1 Water rower 有权
公开(公告)号：USD985695S1
公开(公告)日：2023-05-09
申请号：US29795137
申请日：2021-06-17
申请人： Stephen Smith
设计人： Stephen Smith
摘要： FIG. 1 is a right perspective view of a water rower showing the new design.
FIG. 2 is a rear view thereof.
FIG. 3 is a front view thereof.
FIG. 4 is a left side view thereof; and,
FIG. 5 is a right side view thereof.
The broken lines in the drawings depict portions of the water rower that form no part of the claimed design.

2. 发明申请

US20220224993A2 SYSTEMS AND METHODS FOR PRODUCTION OF FRAGMENTED VIDEO CONTENT 有权
公开(公告)号：US20220224993A2
公开(公告)日：2022-07-14
申请号：US17114186
申请日：2020-12-07
申请人： Brick Eksten , Stephen Smith , Yuval Fisher , Steven Reynolds
发明人： Brick Eksten , Stephen Smith , Yuval Fisher , Steven Reynolds
IPC分类号： H04N21/845 , H04N21/262 , H04N21/2343 , H04N21/24 , H04L29/06 , H04N21/458 , H04N21/488
摘要： A system for producing fragmented video content is provided. The system includes a processing device, a non-transitory data store, and a memory storage device having at least a Manifest Processing Service (MPS) unit stored therein. The MPS unit is configured to generate at least one master manifest and store the master manifest in the non-transitory data store, the master manifest comprising a timing reference for a video fragment of the fragmented video content, wherein the timing reference indicates a temporal boundary of processing for the video fragment.

3. 发明授权

US09035030B2 Human antibodies that bind the P40 subunit of human IL-12 and methods for using the same 有权
标题翻译：结合人IL-12的P40亚基的人抗体及其使用方法
公开(公告)号：US09035030B2
公开(公告)日：2015-05-19
申请号：US13401559
申请日：2012-02-21
申请人： Jochen Salfeld , Michael Roguska , Michael Paskind , Subhashis Banerjee , Daniel Tracey , Michael White , Zehra Kaymakcalan , Boris Labkovsky , Paul Sakorafas , Geertruida M. Veldman , Amy Venturini , Angela Widom , Stuart Friedrich , Nicholas W. Warne , Angela Myles , John Gawain Elvin , Alexander Robert Duncan , Elaine Joy Derbyshire , Sara Carmen , Stephen Smith , Thor Las Holtet , Sarah Leila Du Fou
发明人： Jochen Salfeld , Michael Roguska , Michael Paskind , Subhashis Banerjee , Daniel Tracey , Michael White , Zehra Kaymakcalan , Boris Labkovsky , Paul Sakorafas , Geertruida M. Veldman , Amy Venturini , Angela Widom , Stuart Friedrich , Nicholas W. Warne , Angela Myles , John Gawain Elvin , Alexander Robert Duncan , Elaine Joy Derbyshire , Sara Carmen , Stephen Smith , Thor Las Holtet , Sarah Leila Du Fou
IPC分类号： C07K16/24 , C12P21/08 , A61K39/395 , A61K39/00 , C07K16/18 , C07K16/00 , C07K14/54 , A61K38/20
CPC分类号： C07K16/244 , A61K9/0019 , A61K38/208 , A61K39/00 , A61K39/3955 , A61K39/39591 , A61K45/06 , A61K47/20 , A61K47/22 , A61K47/26 , A61K2039/505 , C07K14/5434 , C07K16/00 , C07K16/18 , C07K2317/21 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/94 , Y10S514/863 , Y10S514/885 , Y10S514/886
摘要： Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.
摘要翻译：公开了特异性结合人白细胞介素-12（hIL-12）的人抗体，优选重组人抗体。优选的抗体对hIL-12具有高亲和力，并在体外和体内中和hIL-12活性。本发明的抗体可以是全长抗体或其抗原结合部分。本发明的抗体或抗体部分可用于检测hIL-12和抑制hIL-12活性，例如在患有hIL-12活性有害的病症的人类受试者中。用于表达本发明的重组人抗体的核酸，载体和宿主细胞以及合成重组人抗体的方法也包括在本发明中。

4. 发明授权

US08765918B2 Human antibodies that bind human interleukin-12 有权
标题翻译：结合人白介素12的人抗体
公开(公告)号：US08765918B2
公开(公告)日：2014-07-01
申请号：US13429104
申请日：2012-03-23
申请人： Jochen G. Salfeld , Michael Roguska , Michael Paskind , Subhashis Banerjee , Daniel Edward Tracey , Michael White , Zehra Kaymakcalan , Boris Labkovsky , Paul Sakorafas , Geertruida M. Veldman , Amy Venturini , Angela Widom , Stuart Friedrich , Nicholas W. Warne , Angela Myles , John Gawain Elvin , Alexander Robert Duncan , Elaine Joy Derbyshire , Sara Carmen , Stephen Smith , Thor Las Holtet , Sarah Leila Du Fou
发明人： Jochen G. Salfeld , Michael Roguska , Michael Paskind , Subhashis Banerjee , Daniel Edward Tracey , Michael White , Zehra Kaymakcalan , Boris Labkovsky , Paul Sakorafas , Geertruida M. Veldman , Amy Venturini , Angela Widom , Stuart Friedrich , Nicholas W. Warne , Angela Myles , John Gawain Elvin , Alexander Robert Duncan , Elaine Joy Derbyshire , Sara Carmen , Stephen Smith , Thor Las Holtet , Sarah Leila Du Fou
IPC分类号： C07K16/24 , A61K39/395 , A61K38/00
CPC分类号： C07K16/244 , A61K9/0019 , A61K38/208 , A61K39/00 , A61K39/3955 , A61K39/39591 , A61K45/06 , A61K47/20 , A61K47/22 , A61K47/26 , A61K2039/505 , C07K14/5434 , C07K16/00 , C07K16/18 , C07K2317/21 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/94 , Y10S514/863 , Y10S514/885 , Y10S514/886
摘要： Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.
摘要翻译：公开了特异性结合人白细胞介素-12（hIL-12）的人抗体，优选重组人抗体。优选的抗体对hIL-12具有高亲和力，并在体外和体内中和hIL-12活性。本发明的抗体可以是全长抗体或其抗原结合部分。本发明的抗体或抗体部分可用于检测hIL-12和抑制hIL-12活性，例如在患有hIL-12活性有害的病症的人类受试者中。用于表达本发明的重组人抗体的核酸，载体和宿主细胞以及合成重组人抗体的方法也包括在本发明中。

5. 发明申请

US20140155784A1 SIGNAL PROCESSING METHOD AND APPARATUS 有权
标题翻译：信号处理方法和装置
公开(公告)号：US20140155784A1
公开(公告)日：2014-06-05
申请号：US13980320
申请日：2012-01-18
申请人： Stephen Smith
发明人： Stephen Smith
IPC分类号： A61B5/11
CPC分类号： A61B5/1101 , A61B5/1125 , G06K9/00536 , G06K9/6229
摘要： The invention provides signal processing algorithms and apparatus for detecting bradykinesia, tremor, or other symptoms of neurological dysfunction in subjects, using three-dimensional sensors to tract finger and hand position. The invention provides Cartesian Genetic Programming networks and particular function blocks for such networks to enable identification of subjects exhibiting such symptoms.
摘要翻译：本发明提供用于检测受试者的运动障碍，震颤或其他神经功能障碍症状的信号处理算法和装置，其使用三维传感器来管理手指和手部位置。本发明提供了笛卡尔基因编程网络和用于这种网络的特定功能块，以使得能够识别表现出这种症状的受试者。

6. 发明授权

US08356696B1 Air-operated device and method for lubricating components with elimination of lubricant waste 有权
标题翻译：用于润滑组件的气动装置和方法，消除润滑剂废物
公开(公告)号：US08356696B1
公开(公告)日：2013-01-22
申请号：US12483931
申请日：2009-06-12
申请人： Brian Carroll , Michael Neu , Chris Petty , Dudley Headley , David McCoy , Stephen Smith
发明人： Brian Carroll , Michael Neu , Chris Petty , Dudley Headley , David McCoy , Stephen Smith
IPC分类号： F01M1/00 , F01M11/00 , F16N7/34 , B05B5/025 , B05B7/00 , A61M11/06
CPC分类号： F16N7/32
摘要： A system and method for lubricating components where the lubricant is applied in mist form within a substantially enclosed cavity. The cavity contains a draining aperture which collects excess lubricant for subsequent re-use by the system. The cavity is defined by a spray head that includes a base having attached thereto a cover plate with an opening adapted to receive therethrough a component to be lubricated. The cavity and lubrication chamber prevents the escape of excess lubricant. The collection and reuse of excess lubricant provides a closed loop system that reduces lubricant waste.
摘要翻译：一种用于润滑部件的系统和方法，其中润滑剂以雾形式施加在基本封闭的腔内。空腔包含一个排放孔，其收集多余的润滑剂以供系统随后重复使用。空腔由喷头限定，喷头包括底座，其附接有具有开口的底板，该开口适于容纳待润滑的部件。空腔和润滑室可防止多余润滑剂溢出。多余润滑剂的收集和再利用提供了一种减少润滑剂浪费的闭环系统。

7. 发明申请

US20120308514A1 HUMAN ANTIBODIES THAT BIND HUMAN IL-12 AND METHODS FOR PRODUCING 有权
公开(公告)号：US20120308514A1
公开(公告)日：2012-12-06
申请号：US13429104
申请日：2012-03-23
申请人： Jochen Salfeld , Michael Roguska , Michael Paskind , Subhashis Banerjee , Daniel Tracey , Michael White , Zehra Kaymakcalan , Boris Labkovsky , Paul Sakorafas , Geertruida M. Veldman , Amy Venturini , Angela Widom , Stuart Friedrich , Nicholas W. Warne , Angela Myles , John Gawain Elvin , Alexander Robert Duncan , Elaine Joy Derbyshire , Sara Carmen , Stephen Smith , Thor Las Holtet , Sarah Leila Du Fou
发明人： Jochen Salfeld , Michael Roguska , Michael Paskind , Subhashis Banerjee , Daniel Tracey , Michael White , Zehra Kaymakcalan , Boris Labkovsky , Paul Sakorafas , Geertruida M. Veldman , Amy Venturini , Angela Widom , Stuart Friedrich , Nicholas W. Warne , Angela Myles , John Gawain Elvin , Alexander Robert Duncan , Elaine Joy Derbyshire , Sara Carmen , Stephen Smith , Thor Las Holtet , Sarah Leila Du Fou
IPC分类号： A61K39/395 , A61K38/19 , A61P19/02 , A61P1/00 , A61P1/04 , A61P9/10 , A61P11/06 , A61P13/12 , A61P1/16 , A61P25/28 , A61P25/16 , A61K38/20 , A61P3/10
CPC分类号： C07K16/244 , A61K9/0019 , A61K38/208 , A61K39/00 , A61K39/3955 , A61K39/39591 , A61K45/06 , A61K47/20 , A61K47/22 , A61K47/26 , A61K2039/505 , C07K14/5434 , C07K16/00 , C07K16/18 , C07K2317/21 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/94 , Y10S514/863 , Y10S514/885 , Y10S514/886
摘要： Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.

8. 发明申请

US20090102443A1 H-bridge pulse generator 审中-公开
标题翻译： H桥脉冲发生器
公开(公告)号：US20090102443A1
公开(公告)日：2009-04-23
申请号：US11786538
申请日：2007-04-12
申请人： Stephen Smith
发明人： Stephen Smith
IPC分类号： G05F1/10
CPC分类号： B06B1/0269
摘要： A new type of circuit for driving an electromagnetic acoustic transducer (EMAT) which does not employ push-pull technology using a transformer but instant uses a novel circuit employing a series of Mosfet switches to correct all the disadvantages of using a transformer.
摘要翻译：用于驱动电磁声换能器（EMAT）的新型电路，其不采用使用变压器的推挽技术，而是使用采用一系列Mosfet开关的新颖电路来校正使用变压器的所有缺点。

9. 发明申请

US20080253755A1 Fragrance emanation system 有权
标题翻译：香水散发系统
公开(公告)号：US20080253755A1
公开(公告)日：2008-10-16
申请号：US11906418
申请日：2007-10-02
申请人： Stephen Smith , David Baraky , Robert Bussom , Harry Slatkin
发明人： Stephen Smith , David Baraky , Robert Bussom , Harry Slatkin
IPC分类号： A61L9/03 , A61L9/00 , B05B1/24
CPC分类号： A61L9/037
摘要： The fragrance emanation system includes a container for holding preferably a fragranced liquid or gel, a housing for holding the container, and a wick. The housing contains a socket for attaching to the container, a cavity for receiving the container and a door for enclosing the container. One end of the wick protrudes from the container. An electrical circuit is included having a heater for heating the protruding end of the wick and electrical connectors coupled to the circuit to receive current from a power source to provide the current to the heater. The heater heats and evaporates the liquid within the wick, thereby accelerating the emission of vapors from the evaporated liquid. The door includes a window, a bottom and a mechanism for holding the door closed to assist in holding the container in engagement with the socket.
摘要翻译：香味散发系统包括用于容纳香味液体或凝胶的容器，用于容纳容器的壳体和吸液芯。壳体包括用于附接到容器的插座，用于容纳容器的空腔和用于封闭容器的门。灯芯的一端从容器突出。包括一个电路，其具有用于加热芯的突出端的加热器和耦合到电路的电连接器以从电源接收电流以向加热器提供电流。加热器加热并蒸发芯中的液体，从而加速蒸发的液体的蒸气排放。该门包括一个窗口，一个底部和一个用于将门关闭以保持容器与插座接合的机构。

10. 发明申请

US20080182319A1 METHODS OF OBTAINING A SPECIFIC BINDING MEMBER THAT BINDS EOTAXIN 有权
标题翻译：获得特定结合成员的方法
公开(公告)号：US20080182319A1
公开(公告)日：2008-07-31
申请号：US11958210
申请日：2007-12-17
申请人： Tristan John Vaughan , Alison Jane Wilton , Stephen Smith , Sarah Helen Main
发明人： Tristan John Vaughan , Alison Jane Wilton , Stephen Smith , Sarah Helen Main
IPC分类号： C12N1/21 , C12N15/12 , C12N5/10 , C12N1/19 , C12N15/13
CPC分类号： C07K16/24 , A61K2039/505 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2319/00 , C12P21/00
摘要： Specific binding members directed to eotaxin-1, in particular human antibodies and antibody fragments against human eotaxin-1 and especially those which neutralise eotaxin-1 activity. The antibodies VH and/or VL domain of the scFv fragment herein termed CAT-212 and of the IgG4 antibody herein termed CAT 213. One or more complementary determining regions (CDRs) of the CAT-212/-213 VH and/or VL domains, especially VH CRD3 in other antibody framework regions. Compositions containing specific binding members, and their use in methods of inhibiting or neutralising eotaxin, including methods of treatment of the human or animal body by therapy.
摘要翻译：针对嗜酸细胞活化趋化因子-1的特异性结合成员，特别是针对人类嗜酸细胞活化趋化因子-1的人抗体和抗体片段，特别是中和嗜酸性粒细胞趋化因子-1活性的那些。本文称为CAT-212和本文称为CAT 213的IgG4抗体的scFv片段的抗体V H和/或VL结构域.CAT-212 / -213VV和/或VL结构域的一个或多个互补决定区（CDR），特别是VH CRD3在其他抗体框架区域。含有特异性结合成员的组合物及其在抑制或中和嗜酸性粒细胞趋化因子的方法中的用途，包括通过治疗来治疗人或动物体的方法。

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