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1. 发明授权

US08226971B2 Catheter lock solution comprising citrate and a paraben 有权
标题翻译：导管锁定溶液，其包含柠檬酸盐和对羟基苯甲酸酯
公开(公告)号：US08226971B2
公开(公告)日：2012-07-24
申请号：US12792286
申请日：2010-06-02
申请人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
发明人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
IPC分类号： A01N37/10
CPC分类号： A01N37/10 , A01N37/04 , A61L29/14 , A61L29/16 , A61L2300/404 , A61L2300/42 , A61M25/0017
摘要： This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.
摘要翻译：本发明涉及将导管锁定溶液输注到留置导管中的组合物，方法，装置和试剂盒。本发明的组合物，方法，装置和试剂盒有助于减少导管中的微生物感染和导管闭塞的影响。本发明提供的锁定溶液包括柠檬酸盐和对羟基苯甲酸酯。溶液优选具有适于在锁定期间将溶液保留在导管中的密度。本发明提供的另一种锁定溶液包括柠檬酸盐，对羟基苯甲酸酯和光氧化剂，例如亚甲基蓝。

2. 发明申请

US20120277314A1 CATHETER LOCK SOLUTION COMPRISING CITRATE AND A PARABEN 审中-公开
标题翻译：包括CITRATE和PARABEN的CATHETER LOCK解决方案
公开(公告)号：US20120277314A1
公开(公告)日：2012-11-01
申请号：US13546958
申请日：2012-07-11
申请人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
发明人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
IPC分类号： A61K31/235
CPC分类号： A01N37/10 , A01N37/04 , A61L29/14 , A61L29/16 , A61L2300/404 , A61L2300/42 , A61M25/0017
摘要： This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.
摘要翻译：本发明涉及将导管锁定溶液输注到留置导管中的组合物，方法，装置和试剂盒。本发明的组合物，方法，装置和试剂盒有助于减少导管中的微生物感染和导管闭塞的影响。本发明提供的锁定溶液包括柠檬酸盐和对羟基苯甲酸酯。溶液优选具有适于在锁定期间将溶液保留在导管中的密度。本发明提供的另一种锁定溶液包括柠檬酸盐，对羟基苯甲酸酯和光氧化剂，例如亚甲基蓝。

3. 发明授权

US07749529B2 Catheter lock solution comprising citrate and a paraben 有权
标题翻译：导管锁定溶液，其包含柠檬酸盐和对羟基苯甲酸酯
公开(公告)号：US07749529B2
公开(公告)日：2010-07-06
申请号：US11053130
申请日：2005-02-08
申请人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
发明人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
IPC分类号： A61K31/5415 , A61K31/235 , A61K31/19 , A61F2/00
CPC分类号： A01N37/10 , A01N37/04 , A61L29/14 , A61L29/16 , A61L2300/404 , A61L2300/42 , A61M25/0017
摘要： This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.
摘要翻译：本发明涉及将导管锁定溶液输注到留置导管中的组合物，方法，装置和试剂盒。本发明的组合物，方法，装置和试剂盒有助于减少导管中的微生物感染和导管闭塞的影响。本发明提供的锁定溶液包括柠檬酸盐和对羟基苯甲酸酯。溶液优选具有适于在锁定期间将溶液保留在导管中的密度。本发明提供的另一种锁定溶液包括柠檬酸盐，对羟基苯甲酸酯和光氧化剂，例如亚甲基蓝。

4. 发明申请

US20130178526A1 CATHETER LOCK SOLUTION COMPRISING CITRATE AND A PARABEN 有权
标题翻译：包括CITRATE和PARABEN的CATHETER LOCK解决方案
公开(公告)号：US20130178526A1
公开(公告)日：2013-07-11
申请号：US13779637
申请日：2013-02-27
申请人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
发明人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
IPC分类号： A01N37/10 , A01N37/04
CPC分类号： A01N37/10 , A01N37/04 , A61L29/14 , A61L29/16 , A61L2300/404 , A61L2300/42 , A61M25/0017
摘要： This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.
摘要翻译：本发明涉及将导管锁定溶液输注到留置导管中的组合物，方法，装置和试剂盒。本发明的组合物，方法，装置和试剂盒有助于减少导管中的微生物感染和导管闭塞的影响。本发明提供的锁定溶液包括柠檬酸盐和对羟基苯甲酸酯。溶液优选具有适于在锁定期间将溶液保留在导管中的密度。本发明提供的另一种锁定溶液包括柠檬酸盐，对羟基苯甲酸酯和光氧化剂，例如亚甲基蓝。

5. 发明申请

US20100240750A1 CATHETER LOCK SOLUTION COMPRISING CITRATE AND A PARABEN 有权
标题翻译：包括CITRATE和PARABEN的CATHETER LOCK解决方案
公开(公告)号：US20100240750A1
公开(公告)日：2010-09-23
申请号：US12792286
申请日：2010-06-02
申请人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
发明人： Stephen R. Ash , Janusz Steczko , Gary L. Swanson
IPC分类号： A01N37/10
CPC分类号： A01N37/10 , A01N37/04 , A61L29/14 , A61L29/16 , A61L2300/404 , A61L2300/42 , A61M25/0017
摘要： This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.
摘要翻译：本发明涉及将导管锁定溶液输注到留置导管中的组合物，方法，装置和试剂盒。本发明的组合物，方法，装置和试剂盒有助于减少导管中的微生物感染和导管闭塞的影响。本发明提供的锁定溶液包括柠檬酸盐和对羟基苯甲酸酯。溶液优选具有适于在锁定期间将溶液保留在导管中的密度。本发明提供的另一种锁定溶液包括柠檬酸盐，对羟基苯甲酸酯和光氧化剂，例如亚甲基蓝。

6. 发明授权

US4697572A Apparatus for slurrifying snow-debris 失效
标题翻译：用于sl ying积雪的装置
公开(公告)号：US4697572A
公开(公告)日：1987-10-06
申请号：US929799
申请日：1986-11-13
申请人： Steven P. James , Roger W. Karr , Gary L. Swanson
发明人： Steven P. James , Roger W. Karr , Gary L. Swanson
IPC分类号： E01H5/10 , E01C19/45 , F24H1/00
CPC分类号： E01H5/102
摘要： Apparatus and method utilize an open-top hopper having an upper cascade-zone and a lower pool-zone. Crude snow-debris is intermittently dumped into the hopper open-top and there operationally admixed with low-temperature water; this admixture is converted by cascade-zone comminution drums into a rough-slurry that pools at the pool-zone. Within the pool-zone, the rough-slurry is agitated, preferably with a revolvable bladed shaft, into a smoothly flowable-slurry that is dischargeable through an apparatus outlet to a remote disposal site which might be a municipal sewerline. Preferably, the apparatus takes the form of a wheeled vehicle, has a lengthily agitated pool-zone extending beyond the hopper, and is equippable with other desireable optional structural features.
摘要翻译：装置和方法利用具有上级联区和下游池区的开顶式料斗。粗碎屑被间歇地倾倒进料斗开口，并与低温水混合; 该混合物通过级联粉碎转炉转化成在池区域中的粗糙浆料。在池区内，将粗浆料搅拌，优选具有可旋转的叶片轴，成为可平滑流动的浆料，其可通过装置出口排放到可能是市政下水道的远程处置场所。优选地，该装置采用轮式车辆的形式，其具有延伸超过料斗的长时间搅动的池区域，并且可装配有其他可期望的可选结构特征。

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