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1. 发明授权

US08255054B2 MRI compatible implanted electronic medical device 失效
标题翻译： MRI兼容植入电子医疗器械
公开(公告)号：US08255054B2
公开(公告)日：2012-08-28
申请号：US11553228
申请日：2006-10-26
申请人： Stephen Denker , Arthur J. Beutler , Cherik Bulkes
发明人： Stephen Denker , Arthur J. Beutler , Cherik Bulkes
IPC分类号： A61N1/375
CPC分类号： A61N1/375 , A61N1/086 , A61N1/3718
摘要： An implantable electronic medical device is compatible with a magnetic resonance imaging (MRI) scanner. The device has a housing with exterior walls, each formed by a dielectric substrate with electrically conductive layers on interior and exterior surfaces. A series of slots divide each layer into segments. Segmenting the layers provides high impedance to eddy currents produced by fields of the MRI scanner, while capacitive coupling of the segments provides radio frequency shielding for components inside the housing. Electrical leads extending from the housing have a pair of coaxially arranged conductors and traps that attenuate currents induced in the conductors by the fields of the MRI scanner.
摘要翻译：可植入电子医疗装置与磁共振成像（MRI）扫描器兼容。该装置具有带有外壁的壳体，每个由内部和外部表面上具有导电层的电介质基底形成。一系列插槽将每个层划分成多个段。这些层的分段对于由MRI扫描仪的场产生的涡流提供高阻抗，而段的电容耦合为壳体内的部件提供射频屏蔽。从壳体延伸的电引线具有一对同轴布置的导体和陷阱，其通过MRI扫描仪的场来衰减在导体中感应的电流。

2. 发明授权

US06445953B1 Wireless cardiac pacing system with vascular electrode-stents 有权
标题翻译：具有血管电极支架的无线心脏起搏系统
公开(公告)号：US06445953B1
公开(公告)日：2002-09-03
申请号：US09760936
申请日：2001-01-16
申请人： Cherik Bulkes , Arthur J. Beutler , Stephen Denker
发明人： Cherik Bulkes , Arthur J. Beutler , Stephen Denker
IPC分类号： A61N1362
CPC分类号： A61N1/37211 , A61N1/37223
摘要： A cardiac pacing apparatus has a source of pacing pulses that are transmitted through the animal by a radio frequency signal. An electrode-stent is implanted in a blood vessel adjacent to the point at which stimulation is desired. The electrode-stent contains an electrical circuit that is tuned to the radio frequency signal and which responds to receipt of that signal by applying an electric current to tissue of the animal.
摘要翻译：心脏起搏装置具有通过射频信号传播通过动物的起搏脉冲源。将电极支架植入与需要刺激的点相邻的血管中。电极支架包含调谐到射频信号的电路，并且通过向动物的组织施加电流来响应该信号的接收。

3. 发明授权

US07769466B2 Class-E radio frequency amplifier for use with an implantable medical device 有权
标题翻译： Class-E射频放大器，用于可植入医疗设备
公开(公告)号：US07769466B2
公开(公告)日：2010-08-03
申请号：US11678263
申请日：2007-02-23
申请人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
发明人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
IPC分类号： A61N1/00
CPC分类号： A61N1/3787 , H03F1/34 , H03F3/217 , H03F3/2176 , H03F2200/351
摘要： A medical apparatus includes an extracorporeal power source that transmits electrical power via a radio frequency signal to a medical device implanted inside an animal. The extracorporeal power source has a Class-E amplifier with a choke and a semiconductor switch connected in series between a source of a supply voltage and circuit ground. An output node of the amplifier is formed between choke and the switch and connected to a transmitter antenna. A shunt capacitor couples the amplifier's output node to the circuit ground. Controlled operation of the switch produces bursts of the radio frequency signal that are pulse width modulated to control the amount of energy being sent to the implanted medical device.
摘要翻译：医疗装置包括通过射频信号将电力传送到植入动物内的医疗装置的体外电源。体外电源具有E级放大器，其中扼流圈和半导体开关串联连接在电源电压源和电路接地之间。放大器的输出节点形成在扼流圈和开关之间并连接到发射器天线。分流电容将放大器的输出节点耦合到电路地。交换机的受控操作产生脉冲宽度调制的射频信号脉冲，以控制发送到植入医疗装置的能量的量。

4. 发明授权

US07749265B2 Radio frequency antenna for a wireless intravascular medical device 失效
标题翻译：射频天线用于无线血管内医疗设备
公开(公告)号：US07749265B2
公开(公告)日：2010-07-06
申请号：US11243790
申请日：2005-10-05
申请人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
发明人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
IPC分类号： A61F2/06
CPC分类号： A61N1/3787 , A61N1/37205 , A61N1/37229 , H01Q1/273 , H01Q1/40 , H01Q7/00
摘要： A radio frequency antenna is provided for use with a medical device for implantation into an animal. The antenna comprises a coil formed by a wire that includes a core formed of a shape-memory material with an electrically conductive first layer applied to an outer surface of the core. A second layer, of an electrically insulating and biologically compatible material, extends around the first layer. If necessary to reduce friction a lubricant is place between the first and second layers. If second layer is formed of porous material or a non-biological compatible material, a biological compatible outer layer surrounds the second layer thereby providing a barrier that is impermeable to body fluids of the animal.
摘要翻译：提供射频天线用于与用于植入动物的医疗装置一起使用。该天线包括由导线形成的线圈，该线圈包括由形状记忆材料形成的芯体，其具有施加到芯体外表面的导电第一层。电绝缘和生物相容的材料的第二层围绕第一层延伸。如果需要减少摩擦，润滑剂就位于第一和第二层之间。如果第二层由多孔材料或非生物相容的材料形成，则生物相容的外层包围第二层，从而提供对动物的体液不可透过的屏障。

5. 发明授权

US07720547B2 Extracorporeal power supply with a wireless feedback system for an implanted medical device 有权
标题翻译：具有用于植入式医疗装置的无线反馈系统的体外电源
公开(公告)号：US07720547B2
公开(公告)日：2010-05-18
申请号：US11325130
申请日：2006-01-04
申请人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
发明人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
IPC分类号： A61N1/378
CPC分类号： A61N1/3787
摘要： A medical device adapted for implantation into a patient receives electrical power from an extracorporeal power supply. The medical device has a first receiver for a first wireless signal, a power circuit that extracts energy from the first wireless signal to power the medical device, and a feedback signal generator that transmits a second wireless signal indicating a magnitude of energy extracted from the first wireless signal. The extracorporeal power supply includes a source of electrical power and a power transmitter that emits the first wireless signal. A second receiver enables the extracorporeal power supply to receive the second wireless signal. A feedback controller manipulates the first wireless signal in response to the second wireless signal to ensure that sufficient electrical energy is provided to the medical device without wasting electrical power from the source.
摘要翻译：适于植入患者的医疗装置从体外电源接收电力。医疗设备具有用于第一无线信号的第一接收器，从第一无线信号提取能量以为医疗设备供电的电源电路;以及反馈信号发生器，其发送指示从第一无线信号提取的能量的大小的第二无线信号无线信号。体外电源包括电源和发射第一无线信号的功率发射器。第二接收器使得体外电源能够接收第二无线信号。反馈控制器响应于第二无线信号操纵第一无线信号，以确保向医疗设备提供足够的电能，而不会浪费来自源的电力。

6. 发明授权

US07711434B2 Wireless intravascular medical device with a double helical antenna assembly 失效
标题翻译：具有双螺旋天线组件的无线血管内医疗装置
公开(公告)号：US07711434B2
公开(公告)日：2010-05-04
申请号：US11736227
申请日：2007-04-17
申请人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
发明人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
IPC分类号： A61N1/08
CPC分类号： A61N1/37229 , A61N1/375
摘要： A medical device, such as a cardiac pacing device for an animal, includes an intravascular antenna that has a first coil for engaging a wall of a first blood vessel to receive a radio frequency signal. The first coil includes a first winding wound helically in a rotational direction along a longitudinal axis from a first end of the coil to a second end. A second winding that is connected to the a first winding at the second end, is wound helically in the same rotational direction along the longitudinal axis from the second end to the first end. An electronic circuit is implanted in the animal and is connected to the antenna to receive an electrical signal therefrom.
摘要翻译：诸如用于动物的心脏起搏装置的医疗装置包括血管内天线，其具有用于接合第一血管的壁以接收射频信号的第一线圈。第一线圈包括沿着从线圈的第一端到第二端的纵向轴线的旋转方向螺旋形地缠绕的第一线圈。在第二端连接到第一绕组的第二绕组沿着从第二端到第一端的纵向轴线在相同的旋转方向上螺旋地卷绕。将电子电路注入动物并连接到天线以从其接收电信号。

7. 发明授权

US07295879B2 Double helical antenna assembly for a wireless intravascular medical device 有权
标题翻译：用于无线血管内医疗设备的双螺旋天线组件
公开(公告)号：US07295879B2
公开(公告)日：2007-11-13
申请号：US11166889
申请日：2005-06-24
申请人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
发明人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
IPC分类号： A61N1/00
CPC分类号： A61N1/37229 , A61N1/375
摘要： A medical device, such as a cardiac pacing device for an animal, includes an intravascular antenna that has a first coil for engaging a wall of a first blood vessel to receive a radio frequency signal. The first coil includes a first winding wound helically in a rotational direction along a longitudinal axis from a first end of the coil to a second end. A second winding that is connected to the a first winding at the second end, is wound helically in the same rotational direction along the longitudinal axis from the second end to the first end. An electronic circuit is implanted in the animal and is connected to the antenna to receive an electrical signal therefrom.
摘要翻译：诸如用于动物的心脏起搏装置的医疗装置包括血管内天线，其具有用于接合第一血管的壁以接收射频信号的第一线圈。第一线圈包括沿着从线圈的第一端到第二端的纵向轴线的旋转方向螺旋形地缠绕的第一线圈。在第二端连接到第一绕组的第二绕组沿着从第二端到第一端的纵向轴线在相同的旋转方向上螺旋地卷绕。将电子电路注入动物，并连接到天线以从其接收电信号。

8. 发明授权

US07826903B2 Radio frequency antenna for a wireless intravascular medical device 有权
标题翻译：射频天线用于无线血管内医疗设备
公开(公告)号：US07826903B2
公开(公告)日：2010-11-02
申请号：US11877921
申请日：2007-10-24
申请人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
发明人： Stephen Denker , Cherik Bulkes , Arthur J. Beutler
IPC分类号： A61N1/08
CPC分类号： A61N1/3787 , A61N1/37205 , A61N1/37229 , H01Q1/273 , H01Q1/40 , H01Q7/00
摘要： A radio frequency antenna is provided for use with a medical device for implantation into an animal. The antenna comprises a coil formed by a wire that includes a core formed of a shape-memory material with an electrically conductive first layer applied to an outer surface of the core. A second layer, of an electrically insulating and biologically compatible material, extends around the first layer. If necessary to reduce friction, a lubricant is placed between the first and second layers. If second layer is formed of a porous material or a non-biological compatible material, a biological compatible outer layer surrounds the second layer thereby providing a barrier that is impermeable to body fluids of the animal.
摘要翻译：提供射频天线用于与用于植入动物的医疗装置一起使用。该天线包括由导线形成的线圈，该线圈包括由形状记忆材料形成的芯体，其具有施加到芯体外表面的导电第一层。电绝缘和生物相容的材料的第二层围绕第一层延伸。如果需要减少摩擦，则在第一和第二层之间放置润滑剂。如果第二层由多孔材料或非生物相容的材料形成，则生物相容的外层围绕第二层，从而提供对动物体液不可透过的屏障。

9. 发明授权

US07382128B2 Magnetic resonance imaging system with a Class-E radio frequency amplifier 失效
标题翻译：具有E类射频放大器的磁共振成像系统
公开(公告)号：US07382128B2
公开(公告)日：2008-06-03
申请号：US11678226
申请日：2007-02-23
申请人： Cherik Bulkes , Stephen Denker , Arthur J. Beutler
发明人： Cherik Bulkes , Stephen Denker , Arthur J. Beutler
IPC分类号： G01V3/00
CPC分类号： G01R33/34076 , G01R33/34046 , G01R33/3453 , G01R33/3614
摘要： A Class-E amplifier has been adapted for use in the radio frequency section of a magnetic resonance imaging (MRI) system. A drive signal is produced by modulating the envelope of a radio frequency carrier signal and then is applied to a switch in the Class-E amplifier. The switch is connected in series with a choke between a supply voltage terminal and circuit ground with an output node formed between the choke and the switch. The output node is coupled to circuit ground by a shunt capacitor. In a preferred embodiment, a pair of such amplifiers, that are π radians out of phase, are connected to each rung of a transverse electromagnetic transmit array type radio frequency coil of the MRI system.
摘要翻译： E类放大器已经适用于磁共振成像（MRI）系统的射频部分。通过调制射频载波信号的包络产生驱动信号，然后将其应用于E类放大器中的开关。开关与电源电压端子和电路接地之间的扼流器串联连接，并在扼流圈和开关之间形成输出节点。输出节点通过并联电容耦合到电路接地。在优选实施例中，一对这样的放大器，即相位差的pi弧度，连接到MRI系统的横向电磁发射阵列型射频线圈的每个梯级。

10. 发明申请

US20070210867A1 CLASS-E RADIO FREQUENCY POWER AMPLIFIER WITH FEEDBACK CONTROL 失效
标题翻译：具有反馈控制的等级无线电频率放大器
公开(公告)号：US20070210867A1
公开(公告)日：2007-09-13
申请号：US11678247
申请日：2007-02-23
申请人： Cherik Bulkes , Stephen Denker , Arthur J. Beutler
发明人： Cherik Bulkes , Stephen Denker , Arthur J. Beutler
IPC分类号： H03F3/217
CPC分类号： A61N1/3787 , H03F1/34 , H03F3/217 , H03F3/2176 , H03F2200/351
摘要： A Class-E power amplifier includes a choke and a switch connected in series between a source of a supply voltage and circuit ground and connected to an inductively coupled coil. An output node of the amplifier is formed between choke and the switch and connected to a transmitter antenna. A shunt capacitor couples the amplifier's output node to the circuit ground. A feedback signal, indicating an intensity if the signal at the amplifier output node is used to vary the input signal to the Class-E power amplifier and thereby control operation of the switch.
摘要翻译： E类功率放大器包括在电源电压和电路接地之间串联连接并连接到电感耦合线圈的扼流器和开关。放大器的输出节点形成在扼流圈和开关之间并连接到发射器天线。分流电容将放大器的输出节点耦合到电路地。反馈信号，如果放大器输出节点处的信号用于改变到E类功率放大器的输入信号，从而控制开关的操作，则表示强度。

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