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1. 发明申请

US20090187083A1 CATHETER 审中-公开
标题翻译：导管
公开(公告)号：US20090187083A1
公开(公告)日：2009-07-23
申请号：US12355486
申请日：2009-01-16
申请人： Stephen Blatcher , Richard Harley Grenville Owen , Joseph Peter Corrigan , Thomas Neudeck , Andrew Peter Scudamore , Yannick Pierre Louis Hourmand
发明人： Stephen Blatcher , Richard Harley Grenville Owen , Joseph Peter Corrigan , Thomas Neudeck , Andrew Peter Scudamore , Yannick Pierre Louis Hourmand
IPC分类号： A61B5/157 , A61B5/153
CPC分类号： A61B5/153 , A61B5/15003 , A61B5/150282 , A61B5/150389 , A61B5/150511 , A61B5/150755 , A61B5/417 , A61M25/00
摘要： A catheter and associated method for taking a plurality of samples from within a length of a blood vessel. The catheter includes an elongate central body arranged to be inserted into and positioned along a central region of a blood vessel. A plurality of collection areas are defined along the elongate central body for collecting samples at the central region of the blood vessel. A plurality of mixers are provided radially outwardly of the elongate central body and arranged to create a flow of blood from a boundary layer at a wall of the blood vessel to the elongate central body. This enables the collection areas to collect samples from the boundary layer.
摘要翻译：一种用于从血管的长度内取多个样本的导管和相关方法。该导管包括细长的中心体，该中心体布置成插入并沿着血管的中心区域定位。沿着细长的中心体限定多个收集区域，用于在血管的中心区域收集样品。多个混合器被设置在细长的中心体的径向外侧，并被布置成产生从血管壁上的边界层到细长的中心体的血液流。这使收集区域能够从边界层收集样本。

2. 发明授权

US10357194B2 Catheter 有权
公开(公告)号：US10357194B2
公开(公告)日：2019-07-23
申请号：US12355486
申请日：2009-01-16
申请人： Stephen Blatcher , Richard Harley Greenville Owen , Joseph Peter Corrigan , Thomas Neudeck , Andrew Peter Scudamore , Yannick Pierre Louis Hourmand
发明人： Stephen Blatcher , Richard Harley Greenville Owen , Joseph Peter Corrigan , Thomas Neudeck , Andrew Peter Scudamore , Yannick Pierre Louis Hourmand
IPC分类号： A61B5/153 , A61B5/00 , A61M25/00 , A61B5/15
摘要： A catheter and associated method for taking a plurality of samples from within a length of a blood vessel. The catheter includes an elongate central body arranged to be inserted into and positioned along a central region of a blood vessel. A plurality of collection areas are defined along the elongate central body for collecting samples at the central region of the blood vessel. A plurality of mixers are provided radially outwardly of the elongate central body and arranged to create a flow of blood from a boundary layer at a wall of the blood vessel to the elongate central body. This enables the collection areas to collect samples from the boundary layer.

3. 发明授权

US09180258B2 Autoinjector 有权
标题翻译：自动进样器
公开(公告)号：US09180258B2
公开(公告)日：2015-11-10
申请号：US13581564
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20 , A61M5/24
CPC分类号： A61M5/3287 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate housing arranged to contain a syringe, a proximal end (P) with an orifice, wherein the syringe is slidably arranged with respect to the housing. A drive spring upon activation pushes the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), and operates the syringe to supply the dose of medicament (M). An activating means locks the drive spring in a compressed state. The housing distal and a proximal portions are connected by a hinge, and are rotatable about the hinge between an aligned position and a maximum opening angle. A loading bay for holding the syringe is arranged in the proximal portion.
摘要翻译：提供了一种用于施用剂量的液体药物（M）的自动注射器，其具有布置成容纳注射器的细长壳体，具有孔口的近端（P），其中所述注射器相对于所述壳体可滑动地布置。激活时的驱动弹簧将针从壳体内的覆盖位置推入通过孔口并通过近端（P）的前进位置，并操作注射器以供应剂量的药物（M）。激活装置将驱动弹簧锁定在压缩状态。壳体远端和近端部分通过铰链连接，并且可以在对准位置和最大开启角度之间围绕铰链旋转。用于保持注射器的装载隔间布置在近端部分中。

4. 发明申请

US20130138048A1 AUTOINJECTOR 有权
公开(公告)号：US20130138048A1
公开(公告)日：2013-05-30
申请号：US13581564
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/32
CPC分类号： A61M5/3287 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament (M), comprising: an elongate housing arranged to contain a syringe, the housing having a distal end (D) and a proximal end (P) with an orifice, wherein the syringe is slidably arranged with respect to the housing, a drive spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), and operating the syringe to supply the dose of medicament (M), and activating means arranged to lock the drive spring in a compressed state and capable of releasing the drive spring for injection, wherein the elongate housing comprises a distal portion and a proximal portion connected by a hinge, the portions rotatable about the hinge between an aligned position and a maximum opening angle, wherein the drive spring may be compressed by rotating the portions towards the maximum opening angle, wherein the activating means are arranged to lock the drive spring in the compressed state when the portions are rotated at least almost to the maximum opening angle and wherein a loading bay for holding the syringe is arranged in the proximal portion.
摘要翻译：本发明涉及一种用于施用剂量的液体药物（M）的自动注射器，其包括：布置成容纳注射器的细长壳体，所述壳体具有远端（D）和近端（P），所述近端具有孔，其中所述注射器相对于所述壳体可滑动地布置;驱动弹簧，其能够在启动时：将所述针从所述壳体内的覆盖位置推入到穿过所述孔口并经过所述近端（P）的前进位置，并且操作所述注射器提供剂量的药物（M），以及激活装置，其布置成将所述驱动弹簧锁定在压缩状态并且能够释放用于注射的驱动弹簧，其中所述细长壳体包括远端部分和近端部分铰链，所述部分可以在对准位置和最大开启角度之间围绕所述铰链旋转，其中所述驱动弹簧可以通过将所述部分朝向最大开启角度旋转而被压缩，其中所述动作当所述部分至少几乎旋转到最大开启角度时，所述静止装置被布置成将所述驱动弹簧锁定在压缩状态，并且其中用于保持所述注射器的装载间隔布置在所述近端部分中。

5. 发明申请

US20130138049A1 INJECTION DEVICE 有权
标题翻译：注射装置
公开(公告)号：US20130138049A1
公开(公告)日：2013-05-30
申请号：US13581566
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/322 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： The invention relates to an injection device, comprising a syringe with a hollow needle and a stopper for sealing the syringe and displacing a medicament (M) stored in the syringe, the injection device further comprising a drive means, a plunger arranged for pushing against the stopper and an arrangement for transferring a translation of the drive means to the plunger, the arrangement comprising an elongate release latch member pivoted at one end which is connected to either the drive means or the plunger, the release latch member having another end for engaging the respective other one of the drive means or the plunger, wherein the release latch member is arranged to have its non-pivoted other end disengaged by rotation due to contact between at least one ramp and another component when the stopper has at least nearly displaced all of a predefined dose of the medicament (M), wherein a length of the release latch member is specified so as to provide a clearance between the plunger and the drive means when the release latch member is engaged in order to allow at least the plunger, the stopper and the hollow needle to be retracted at least far enough to hide the needle inside the syringe or inside a housing after disengaging the release latch member.
摘要翻译：本发明涉及一种注射装置，其包括具有中空针头的注射器和用于密封注射器并移动存储在注射器中的药物（M）的止动件，该注射装置还包括驱动装置，柱塞，止动器和用于将驱动装置的平移传递到柱塞的装置，该装置包括在连接到驱动装置或柱塞的一端枢转的细长释放闩锁构件，释放闩锁构件具有用于接合所述驱动装置或所述柱塞中的相应的另一个，其中所述释放闩锁构件被布置成使得当所述止动件至少几乎位移至少几乎全部时，所述释放闩锁构件由于至少一个斜坡和另一部件之间的接触而使其不可枢转的另一端由于旋转而脱离预定剂量的药物（M），其中指定释放闩锁构件的长度以便提供柱塞和当释放闩锁构件接合时，驱动装置是为了允许至少使柱塞，止动器和中空针缩回到至少足够远以在将释放闩锁构件分离之后将针隐藏在注射器内部或壳体内部。

6. 发明授权

US09233214B2 Injection device 有权
标题翻译：注射装置
公开(公告)号：US09233214B2
公开(公告)日：2016-01-12
申请号：US13581566
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20 , A61M5/24
CPC分类号： A61M5/322 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： An injection device includes a syringe with a hollow needle and a stopper for sealing the syringe and displacing a medicament stored in the syringe. An arrangement for transferring a translation of a drive means to a plunger for pushing against the stopper includes a release latch pivoted at one end and connected to either the drive means or the plunger. The other end of the release latch engages the other one of the drive means or the plunger. The non-pivoted end of the release latch disengages by rotation upon contact between a ramp and another component when the stopper has displaced most of a predefined medicament dose. The release latch is long enough to provide a clearance between the plunger and the drive means when engaged to allow the plunger, stopper and needle to be retracted inside the syringe or a housing after disengaging the release latch.
摘要翻译：注射装置包括具有中空针的注射器和用于密封注射器并使存储在注射器中的药物移位的止动件。用于将驱动装置的平移传递到用于推动止动件的柱塞的装置包括在一端枢转并连接到驱动装置或柱塞的释放闩锁。释放闩锁的另一端接合驱动装置或柱塞中的另一端。当止动器已经取代大部分预定的药物剂量时，释放闩锁的非转动端部通过斜面和另一部件之间的接触时的旋转而脱离。释放闩锁足够长以在接合时提供柱塞和驱动装置之间的间隙，以允许柱塞，止动器和针在分离释放闩锁之后在注射器或壳体内缩回。

7. 发明授权

US07275537B2 Device for delivering physiologically active agent in powdered form 失效
标题翻译：用于以粉末形式递送生理活性剂的装置
公开(公告)号：US07275537B2
公开(公告)日：2007-10-02
申请号：US10344130
申请日：2001-08-08
申请人： Craig Harvey Nelson , Jeffrey Martin , Andrew Peter Scudamore
发明人： Craig Harvey Nelson , Jeffrey Martin , Andrew Peter Scudamore
IPC分类号： A61M15/00 , A61M16/00
CPC分类号： A61M15/0065 , A61M15/0025 , A61M15/0045 , A61M15/0048 , A61M16/0075 , A61M2202/064 , A61M2205/075 , A61M2210/0618 , A61M2230/005
摘要： A powder delivery device for the delivery into a patient's nasal cavity of a physiologically active agent in powdered form. A closure restricts the unwanted ingress of moisture into the device when the device is not in use. The action of opening or closing this closure may be linked to charging an air reservoir with air and/or moving a fresh powder-containing receptacle into communication with a powder delivery passage.
摘要翻译：一种粉末输送装置，用于以粉末形式输送到患者的鼻腔中的生理活性剂。闭合装置限制当装置不使用时不必要的潮气进入装置。打开或关闭该封闭件的动作可以与将空气储存器充满空气和/或移动含有粉末的新鲜容器与粉末输送通道连通。

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