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1. 发明授权

US08263780B2 Process for the preparation of 2-imino-thiazolidin-4-one derivatives 有权
标题翻译： 2-亚氨基 - 噻唑烷-4-酮衍生物的制备方法
公开(公告)号：US08263780B2
公开(公告)日：2012-09-11
申请号：US12516055
申请日：2007-11-22
申请人： Stefan Abele , Martin Bolli , Gunther Schmidt
发明人： Stefan Abele , Martin Bolli , Gunther Schmidt
IPC分类号： C07D277/54
CPC分类号： C07D277/54
摘要： The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), which thiazolidin-4-one derivatives being described in WO 2005/054215 to act as immunosuppressive agents.
摘要翻译：本发明涉及制备式（I）和（II）的2-亚氨基 - 噻唑烷-4-酮化合物和式（II）化合物的新方法。本发明的式（II）化合物可以用作制备通式（II）的噻唑烷-4-酮衍生物的中间体，其中WO 2005/054215中描述的噻唑烷-4-酮衍生物作为免疫抑制剂。

2. 发明申请

US20120302758A1 NEW PROCESS FOR THE PREPARATION OF 2-IMINO-THIAZOLIDIN-4-ONE DERIVATIVES 有权
标题翻译：制备2-IMINO-THIAZOLIDIN-4-ONE衍生物的新工艺
公开(公告)号：US20120302758A1
公开(公告)日：2012-11-29
申请号：US13565469
申请日：2012-08-02
申请人： Stefan ABELE , Martin Bolli , Gunther Schmidt
发明人： Stefan ABELE , Martin Bolli , Gunther Schmidt
IPC分类号： C07D277/54
CPC分类号： C07D277/54
摘要： The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), said derivatives being described in WO 2005/054215. These compounds of General Formula (II) are described in WO 2005/054215 to act as immunosuppressive agents.
摘要翻译：本发明涉及制备式（I）和（II）的2-亚氨基 - 噻唑烷-4-酮化合物和式（II）化合物的新方法。本发明的式（II）化合物可用作制备通式（II）的噻唑烷-4-酮衍生物的中间体，所述衍生物描述于WO 2005/054215中。这些通式（II）化合物描述于WO 2005/054215中，用作免疫抑制剂。

3. 发明授权

US08912340B2 Process for the preparation of 2-imino-thiazolidin-4-one derivatives 有权
标题翻译： 2-亚氨基 - 噻唑烷-4-酮衍生物的制备方法
公开(公告)号：US08912340B2
公开(公告)日：2014-12-16
申请号：US13565469
申请日：2012-08-02
申请人： Stefan Abele , Martin Bolli , Gunther Schmidt
发明人： Stefan Abele , Martin Bolli , Gunther Schmidt
IPC分类号： C07D277/54
CPC分类号： C07D277/54
摘要： The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), said derivatives being described in WO 2005/054215. These compounds of General Formula (II) are described in WO 2005/054215 to act as immunosuppressive agents.
摘要翻译：本发明涉及制备式（I）和（II）的2-亚氨基 - 噻唑烷-4-酮化合物和式（II）化合物的新方法。本发明的式（II）化合物可用作制备通式（II）的噻唑烷-4-酮衍生物的中间体，所述衍生物描述于WO 2005/054215中。这些通式（II）化合物描述于WO 2005/054215中，用作免疫抑制剂。

4. 发明申请

US20100317867A1 NEW PROCESS FOR THE PREPARATION OF 2-IMINO-THIAZOLIDIN-4-ONE DERIVATIVES 有权
标题翻译：制备2-IMINO-THIAZOLIDIN-4-ONE衍生物的新工艺
公开(公告)号：US20100317867A1
公开(公告)日：2010-12-16
申请号：US12516055
申请日：2007-11-22
申请人： Stefan Abele , Martin Bolli , Gunther Schmidt
发明人： Stefan Abele , Martin Bolli , Gunther Schmidt
IPC分类号： C07D277/54
CPC分类号： C07D277/54
摘要： The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), said derivatives being described in WO 2005/054215. These compounds of General Formula (II) are described in WO 2005/054215 to act as immunosuppressive agents.
摘要翻译：本发明涉及制备式（I）和（II）的2-亚氨基 - 噻唑烷-4-酮化合物和式（II）化合物的新方法。本发明的式（II）化合物可用作制备通式（II）的噻唑烷-4-酮衍生物的中间体，所述衍生物描述于WO 2005/054215中。这些通式（II）化合物描述于WO 2005/054215中，用作免疫抑制剂。

5. 发明申请

US20110201821A2 NEW PROCESS FOR THE PREPARATION OF 2-IMINO-THIAZOLIDIN-4-ONE DERIVATES 有权
标题翻译：制备2-亚氨基 - 噻唑烷-4-酮衍生物的新方法
公开(公告)号：US20110201821A2
公开(公告)日：2011-08-18
申请号：US12516055
申请日：2007-11-22
申请人： Stefan Abele , Martin Bolli , Gunther Schmidt
发明人： Stefan Abele , Martin Bolli , Gunther Schmidt
IPC分类号： C07D277/54
CPC分类号： C07D277/54
摘要： The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), said derivatives being described in WO 2005/054215. These compounds of General Formula (II) are described in WO 2005/054215 to act as immunosuppressive agents.
摘要翻译：本发明涉及制备式（I）和（II）的2-亚氨基 - 噻唑烷-4-酮化合物和式（II）化合物的新方法。本发明的式（II）化合物可用作制备通式（II）的噻唑烷-4-酮衍生物的中间体，所述衍生物描述于WO 2005/054215中。这些通式（II）化合物描述于WO 2005/054215中，用作免疫抑制剂。

6. 发明授权

US09919989B2 Separation sequence for hydrocarbons from a gentle thermal cleavage 有权
公开(公告)号：US09919989B2
公开(公告)日：2018-03-20
申请号：US14238394
申请日：2012-08-02
申请人： Tuat Pham Duc , Gunther Schmidt , Holger Schmigalle , Naree Schmigalle , Stefanie Walter
发明人： Tuat Pham Duc , Gunther Schmidt , Holger Schmigalle , Stefanie Walter
IPC分类号： C07C7/00 , C07C7/04 , C07C7/11 , C10G70/04 , B01D3/14
CPC分类号： C07C7/005 , C07C7/04 , C07C7/11 , C10G70/04 , C07C11/02
摘要： The invention describes a method for separating hydrocarbons in an installation for generating hydrocarbons from a hydrocarbon-containing charge by cleavage. The product gas of the cleavage, which contains gaseous hydrocarbons, is compressed, dried, and supplied as charge material into a separation stage (a front end C3/C4 separation). The front end C3/C4 separation comprises a C4 absorber and a depropanizer. A hydrocarbon fraction consisting of hydrocarbons having a maximum of 3 carbon atoms is obtained as a gaseous overhead product of the C4 absorber. A liquid hydrocarbon fraction consisting of hydrocarbons having at least 4 carbon atoms is obtained as a bottom product of the depropanizer. The front end C3/C4 separation comprises an additional process technological C2/C4 separation stage is arranged between the C4 absorber and the depropanizer.

7. 发明申请

US20150284645A1 PROCESS FOR PREPARING OLEFIN-CONTAINING PRODUCTS BY THERMAL STEAM CRACKING 审中-公开
标题翻译：通过热蒸汽破碎制备含烯烃产品的方法
公开(公告)号：US20150284645A1
公开(公告)日：2015-10-08
申请号：US14440704
申请日：2013-11-07
申请人： Gunther Schmidt , Boris Banovsky , Stefanie Walter
发明人： Gunther Schmidt , Boris Banovsky , Stefanie Walter
IPC分类号： C10G69/06 , C10G9/00
CPC分类号： C10G69/06 , C10G9/00 , C10G9/36 , C10G55/04 , C10G2400/20
摘要： A process for preparing olefinic products by thermal steam cracking of a first furnace feed composed of hydrocarbons in at least one first cracking furnace and of a second furnace feed composed of hydrocarbons in at least one second cracking furnace. The first furnace feed is at least partly converted into a first product stream in the first cracking furnace and the second furnace feed is at least partly converted into a second product stream in the second cracking furnace. A first pyrolysis oil is isolated from the first product stream and is at least partly treated chemically. The first pyrolysis oil is at least partly recirculated as furnace feed from downstream of the chemical treatment to the first cracking furnace. The first cracking furnace and the second cracking furnace are operated under different cracking conditions.
摘要翻译：一种通过在至少一个第一裂解炉中由烃构成的第一炉进料和在至少一个第二裂解炉中由烃组成的第二炉进料的热蒸汽裂化来制备烯烃产物的方法。第一炉料至少部分地转化为第一裂解炉中的第一产物流，第二炉进料在第二裂解炉中至少部分转化为第二产物流。第一热解油从第一产物流中分离并且至少部分地被化学处理。第一热解油至少部分地作为炉料从化学处理的下游再循环到第一裂解炉。第一裂解炉和第二裂解炉在不同的开裂条件下运行。

8. 发明申请

US20100076665A1 Process for the open-and closed-loop control of an internal combustion engine with a common rail system including individual accumulators 有权
公开(公告)号：US20100076665A1
公开(公告)日：2010-03-25
申请号：US12284766
申请日：2008-09-25
申请人： Marc Hehle , Albert Kloos , Jorge Remele , Gunther Schmidt , Ralph Speetzen , Michael Walder , Michael Willmann
发明人： Marc Hehle , Albert Kloos , Jorge Remele , Gunther Schmidt , Ralph Speetzen , Michael Walder , Michael Willmann
IPC分类号： F02D41/00
CPC分类号： F02D41/405 , F02D41/3836 , F02D41/403 , F02D2041/1432 , F02D2041/288 , F02D2200/0602 , F02D2250/04 , F02D2250/14 , Y02T10/44
摘要： For an internal combustion engine with a common rail system including individual accumulators, a process for open- and closed-loop control is proposed, in which the individual accumulator pressure (pE) is detected within a measuring interval and stored, an absolute minimum value of the stored individual accumulator pressure (pE) is interpreted as the end of the main injection, and on the basis of the end of the main injection, a mathematical function is used to calculate a virtual starting time for the main injection. In the measuring interval after the end of the main injection, the individual accumulator pressure (pE) is filtered within a time window, a local minimum value of the filtered individual accumulator pressure is interpreted as the end of a post-injection, and a mathematical function is used to calculate a virtual start of the post-injection.

9. 发明申请

US20090043482A1 Method for controlling an internal combustion engine 有权
标题翻译：用于控制内燃机的方法
公开(公告)号：US20090043482A1
公开(公告)日：2009-02-12
申请号：US12221722
申请日：2008-08-06
申请人： Ralf Speetzen , Gunther Schmidt , Albert Kloos , Andreas Kunz , Michael Willmann , Jorg Remele , Marc Hehle
发明人： Ralf Speetzen , Gunther Schmidt , Albert Kloos , Andreas Kunz , Michael Willmann , Jorg Remele , Marc Hehle
IPC分类号： F02D45/00
CPC分类号： F02D41/0085 , F02D31/007 , F02D41/40 , F02D2041/1419 , Y02T10/44
摘要： A method for controlling an internal combustion engine having a common rail system together with individual accumulators. A rotational speed-control deviation (dn) is determined from a target rotational speed (nSL) that represents the set point for an outer control loop to control the rotational speed, as well as from an actual rotational speed (nIST). A target torque (MSL) is determined from the rotational speed-control deviation (dn) via a rotational speed controller as a master controller. A target injection duration (SD(SOLL)) is determined from the target torque (MSL). The target duration injection (SD(SOLL)) represents the set point for an inner control loop for controlling cylinder-specific injection duration. An injection duration deviation is determined from the target injection duration (SD(SOLL)) and from an actual injection duration. A correcting variable is determined from the injection duration deviation via an injection duration controller as a follow-up controller, and an injection duration is determined from the correcting variable and the target injection duration for activating the injectors.
摘要翻译：一种用于控制具有共轨系统的内燃机与各个蓄能器一起的方法。从表示用于控制转速的外部控制回路的设定点以及实际转速（nIST）的目标转速（nSL）确定转速控制偏差（dn）。通过作为主控制器的转速控制器从转速控制偏差（dn）确定目标转矩（MSL）。从目标转矩（MSL）确定目标喷射持续时间（SD（SOLL））。目标持续时间喷射（SD（SOLL））表示用于控制气缸特定喷射持续时间的内部控制回路的设定点。从目标喷射持续时间（SD（SOLL））和实际喷射持续时间确定喷射持续时间偏差。通过作为后续控制器的喷射持续时间控制器从注射持续时间偏差确定校正变量，并且根据校正变量和用于激活喷射器的目标喷射持续时间来确定喷射持续时间。

10. 发明授权

US5765360A Process for cooling engine walls and wall structure for carrying out the process 失效
标题翻译：用于冷却发动机壁和进行该过程的壁结构的过程
公开(公告)号：US5765360A
公开(公告)日：1998-06-16
申请号：US602216
申请日：1996-02-16
申请人： Gunther Schmidt , Michael Popp
发明人： Gunther Schmidt , Michael Popp
IPC分类号： F02K9/64 , F02C7/20
CPC分类号： F02K9/64
摘要： Cooling of engine walls with fuel, wherein the walls have a structure which has an inner wall, to which hot gas is admitted during the operation, a colder outer wall, as well as a plurality of webs which connect the walls and divide the hollow space present there into a plurality of cooling ducts. The fuel is introduced in the cold state into the wall structure, is delivered through the cooling ducts while absorbing heat via the inner wall, and is subsequently used to generate thrust. A hot fluid flow taken from the engine is admitted during the operation from the outside to the "cold" outer wall of the wall structure, through which fuel flows, and this "cold" outer wall thermally expands as a result, or its thermal contraction is reduced.
摘要翻译：用燃料冷却发动机壁，其中壁具有在操作期间允许热气体的内壁的结构，较冷的外壁以及连接壁并将中空空间分开的多个腹板存在多个冷却导管。燃料以冷态引入壁结构，通过冷却管道输送，同时通过内壁吸收热量，随后用于产生推力。从外部获取的热流体流从外壁到壁结构的“冷”外壁进入，燃料流过该外壁，因此这个“冷”外壁热膨胀，或其热收缩降低了。

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