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1. 发明申请

US20030210765A1 CATHETER TIP X-RAY SOURCE 失效
标题翻译：导管提示X射线源
公开(公告)号：US20030210765A1
公开(公告)日：2003-11-13
申请号：US10142288
申请日：2002-05-09
申请人： Spire Corporation
发明人： Anton C. Greenwald , Ward D. Halverson
IPC分类号： H01J035/00
CPC分类号： H05G1/10 , H01J35/025 , H01J35/18 , H01J35/32 , H01J2235/0236
摘要： The present invention provides a catheter having an x-ray generator unit at its tip which generates x-ray radiation having a wavelength in a range effective for treating biological tissue. In one embodiment, the x-ray generator unit includes a miniature x-ray generator and a miniature transformer that form, in combination, a monolithic device. The transformer includes a primary winding that receives an input voltage in a range of 100 V to 4 kV from a power source, via a flexible cable that runs from the proximal end of the catheter body to its distal end. The transformer further includes a secondary winding that up-converts the input voltage to generate an output voltage in a range of 10 kV to 40 kV to be applied to a cathode of the x-ray generator. The cathode emits electrons in response to the applied voltage, and an extraction electrode guides the emitted electrons to an anode, which is preferably formed of a high-Z refractory metal. The impact of the electrons with the anode effects generation of x-ray radiation, a portion of which is transmitted via an x-ray transmissive window to the outside environment. One significant advantage of the device of the invention is that by employing a lower voltage in the body of the catheter and confining a higher voltage to a short, rigid section at the distal end of the catheter, the device provides enhanced mechanical flexibility and lowers the likelihood of electrical breakdown.
摘要翻译：本发明提供了一种在其尖端处具有x射线发生器单元的导管，其产生具有在有效治疗生物组织的范围内的波长的x射线辐射。在一个实施例中，x射线发生器单元包括组合形成单片器件的微型x射线发生器和微型变压器。该变压器包括初级绕组，其通过从导管主体的近端延伸到其远端的柔性电缆从电源接收在100V至4kV的范围内的输入电压。变压器还包括次级绕组，其对输入电压进行上变频以产生在10kV至40kV的范围内的输出电压以施加到x射线发生器的阴极。阴极响应于施加的电压发射电子，并且提取电极将发射的电子引导到优选由高Z难熔金属形成的阳极。具有阳极的电子的影响影响X射线辐射的产生，其一部分经由x射线透射窗口传输到外部环境。本发明的装置的一个显着优点是通过在导管的主体中采用较低的电压并将更高的电压限制在导管远端处的短的刚性部分，该装置提供增强的机械灵活性并降低电气故障的可能性。

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