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1. 发明申请

US20060166357A1 Integrated microfludic control employing programmable tactile actuators 有权
标题翻译：采用可编程触觉执行器的集成微电极控制
公开(公告)号：US20060166357A1
公开(公告)日：2006-07-27
申请号：US10548692
申请日：2004-03-10
申请人： Shuichi Takayama , Xiaoyue Zhu , Wei Gu , Gary Smith , Yunseok Heo , Brenda Cho , Nobuyuki Futai
发明人： Shuichi Takayama , Xiaoyue Zhu , Wei Gu , Gary Smith , Yunseok Heo , Brenda Cho , Nobuyuki Futai
IPC分类号： C12M3/00
CPC分类号： B01L3/50273 , B01J2219/00396 , B01J2219/00891 , B01L3/502738 , B01L2200/10 , B01L2200/12 , B01L2200/143 , B01L2300/025 , B01L2300/044 , B01L2300/0816 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2300/123 , B01L2400/0481 , B01L2400/0638 , B01L2400/0655 , C12M23/16 , F16K99/0001 , F16K99/0026 , F16K99/0048 , F16K2099/0074 , F16K2099/0078 , F16K2099/008 , F16K2099/0084 , G09B23/12
摘要： Microfluidic devices having active features such as valves, peristaltic pumps, and mixing portions are fabricated to have a thin elastomeric membrane over the active features. The active features are activated by a tactile actuator external to the membrane, for example, a commercial Braille display. The display may be computer controlled, for example by simple text editor software, to activate individual Braille protrusions or a plurality of protrusions to actuate the active portions of the microfluidic device. Integral devices can incorporate the tactile actuators in a single device, but still external to the membrane.
摘要翻译：具有诸如阀，蠕动泵和混合部分的主动特征的微流体装置被制造成在活性特征上具有薄的弹性膜。主动特征由膜外部的触觉致动器激活，例如商业盲文显示器。显示器可以是计算机控制的，例如通过简单的文本编辑器软件来激活单个盲文突起或多个突起来致动微流体装置的有效部分。整体设备可以将触觉致动器结合在单个设备中，但仍然在膜的外部。

2. 发明申请

US20070231901A1 Microfluidic cell culture media 审中-公开
标题翻译：微流体细胞培养基
公开(公告)号：US20070231901A1
公开(公告)日：2007-10-04
申请号：US11607388
申请日：2006-12-01
申请人： Shuichi Takayama , Nobuyuki Futai , Yun Heo , Gary Smith , Jonathan Song
发明人： Shuichi Takayama , Nobuyuki Futai , Yun Heo , Gary Smith , Jonathan Song
IPC分类号： C12N1/20 , C12N5/00
CPC分类号： C12N1/38 , B01L3/5027 , C12M23/16 , C12M23/34
摘要： A microfluidic cell culture media may have an initial concentration of an active material less than a therapeutic window of concentration necessary to provide a cellular mass a therapeutic environment.
摘要翻译：微流体细胞培养基可以具有小于提供细胞群体治疗环境所必需的浓度的治疗窗口的活性物质的初始浓度。

3. 发明申请

US20070084706A1 Microfluidic cell culture device and method for using same 审中-公开
标题翻译：微流体细胞培养装置及其使用方法
公开(公告)号：US20070084706A1
公开(公告)日：2007-04-19
申请号：US11582035
申请日：2006-10-17
申请人： Shuichi Takayama , Lourdes Cabrera , Nobuyuki Futai , Yun Heo , Gary Smith
发明人： Shuichi Takayama , Lourdes Cabrera , Nobuyuki Futai , Yun Heo , Gary Smith
IPC分类号： H01H29/00
CPC分类号： B01L3/502738 , B01L2200/142 , B01L2300/0816 , B01L2300/0887 , B01L2400/0481 , B01L2400/0655 , C12M23/16 , C12M23/34
摘要： Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.
摘要翻译：公开了用于细胞培养的微流体装置及其使用方法。一个装置包括基底和膜。衬底包括与通道流体连通的储存器。可以将生物相容的流体添加到储存器和通道中。储存器被配置为接收和保留细胞块的至少一部分。膜作为生物相容性流体从通道蒸发的障碍。可以加入覆盖流体以覆盖生物相容性流体以防止生物相容性流体的蒸发。

4. 发明申请

US20060270021A1 Integrated microfluidic sperm isolation and insemination device 审中-公开
标题翻译：集成微流体精子分离和授精装置
公开(公告)号：US20060270021A1
公开(公告)日：2006-11-30
申请号：US10559742
申请日：2004-06-07
申请人： Shuichi Takayama , Gary Smith , Ronald Suh
发明人： Shuichi Takayama , Gary Smith , Ronald Suh
IPC分类号： C12M1/00
CPC分类号： B01L3/50273 , B01L3/502753 , B01L3/502776 , B01L2200/0636 , B01L2400/0487
摘要： An integrated microfluidic sperm isolation and oocyte insemination device provides the opportunity to perform in vitro insemination with motilityenhanced sperm samples and with minimal manipulation of fragile oocytes. Sperm sorting is performed in a common sort channel wherein more mobile sperm swim across the interface between co-laminar flows of semen and media fluid.
摘要翻译：整合的微流体精子分离和卵母细胞授精装置提供了运动增强的精子样品进行体外授精并且对脆弱的卵母细胞进行最小操作的机会。精子分选在通常的分类通道中进行，其中更多的移动精子游动穿过精液和培养基流体的共层流之间的界面。

5. 发明申请

US20070090166A1 Microfluidic cell culture device 审中-公开
标题翻译：微流体细胞培养装置
公开(公告)号：US20070090166A1
公开(公告)日：2007-04-26
申请号：US11582027
申请日：2006-10-17
申请人： Shuichi Takayama , Lourdes Cabrera , Yun Heo , Gary Smith
发明人： Shuichi Takayama , Lourdes Cabrera , Yun Heo , Gary Smith
IPC分类号： A47J36/02
CPC分类号： C12N5/0075 , B01L3/5027 , B01L3/5085 , C12M23/12 , C12M23/16 , C12M23/34
摘要： Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.
摘要翻译：公开了用于细胞培养的微流体装置及其使用方法。一个装置包括基底和膜。衬底包括与通道流体连通的储存器。可以将生物相容的流体添加到储存器和通道中。储存器被配置为接收和保留细胞块的至少一部分。膜作为生物相容性流体从通道蒸发的障碍。可以加入覆盖流体以覆盖生物相容性流体以防止生物相容性流体的蒸发。

6. 发明申请

US20190169973A1 Downhole Clutch Joint for Multi-Directionally Rotating Downhole Drilling Assembly 审中-公开
公开(公告)号：US20190169973A1
公开(公告)日：2019-06-06
申请号：US16271563
申请日：2019-02-08
申请人： Gary Smith
发明人： Gary Smith
IPC分类号： E21B44/00 , E21B7/04 , E21B47/024 , E21B47/06 , E21B47/12 , E21B45/00 , E21B3/00 , G05B19/406 , E21B7/06 , E21B4/16 , E21B4/00 , E21B47/18 , G05B15/02
CPC分类号： E21B44/005 , E21B3/00 , E21B4/006 , E21B4/16 , E21B7/04 , E21B7/068 , E21B45/00 , E21B47/024 , E21B47/06 , E21B47/122 , E21B47/18 , G05B15/02 , G05B19/406 , G05B2219/45129
摘要： Embodiments of a downhole drilling assembly generally include rotatable upper and lower drilling assemblies, and a drill bit, wherein an upper drilling assembly contains a mud motor adapted for clockwise stator rotation and counter-clockwise rotor rotation, whereby a lower drilling assembly is rotatable in the opposite direction of the upper drilling assembly or maintainable in a non-rotating state. The apparatus further includes sensors for continuously transmitting information relating thereto to the surface.Embodiments of a downhole clutch joint generally include a box end sub, a pin end sub, and a ratchet sleeve system containing a clutch joint mechanism, wherein the downhole clutch joint prevents rotation of a downhole drilling assembly in an undesired direction.Method embodiments generally include continuously measuring physical properties and/or drilling parameters, continuously transmitting information relating thereto, and controlling lower drilling assembly rotation in a non-rotating state or in the opposite direction of an upper drilling assembly.

7. 发明授权

US09506335B1 Multi-directionally rotating downhole drilling assembly and method 有权
标题翻译：多向旋转井下钻井组件及方法
公开(公告)号：US09506335B1
公开(公告)日：2016-11-29
申请号：US14721644
申请日：2015-05-26
申请人： Gary Smith
发明人： Gary Smith
IPC分类号： E21B4/16 , E21B44/00 , E21B3/00 , E21B45/00 , E21B47/12 , E21B47/06 , E21B47/024 , E21B7/04 , G05B15/02
CPC分类号： E21B44/005 , E21B3/00 , E21B4/006 , E21B4/16 , E21B7/04 , E21B7/068 , E21B45/00 , E21B47/024 , E21B47/06 , E21B47/122 , E21B47/18 , G05B15/02 , G05B19/406 , G05B2219/45129
摘要： Embodiments of a downhole drilling assembly generally include a rotatable lower drilling assembly, a rotatable upper drilling assembly, and a drill bit, wherein the upper drilling assembly contains a mud motor adapted for clockwise rotation of its stator and counter-clockwise rotation of its rotor, whereby the lower drilling assembly is rotatable in the opposite direction of the upper drilling assembly or maintainable in a non-rotating state. The apparatus further includes sensors adapted to continuously measure physical properties and/or drilling parameters and a mechanism for continuously transmitting information relating thereto to the surface.Embodiments of a method for operating a downhole drilling assembly generally include continuously measuring physical properties and/or drilling parameters proximate the drill bit, continuously transmitting information relating thereto to the surface, and controlling rotation of a lower drilling assembly in a non-rotating state or in the opposite direction of an upper drilling assembly by varying drill string rotation.
摘要翻译：用于操作井下钻井组件的方法的实施例通常包括连续地测量靠近钻头的物理特性和/或钻孔参数，将与其相关的信息连续地传递到表面，以及控制下钻井组件在非旋转状态下的旋转，通过改变钻柱旋转在上钻井组件的相反方向上。

8. 发明授权

US09154896B2 Audio spatialization and environment simulation 有权
标题翻译：音频空间化与环境模拟
公开(公告)号：US09154896B2
公开(公告)日：2015-10-06
申请号：US13332699
申请日：2011-12-21
申请人： Jerry Mahabub , Stephan A. Bernsee , Gary Smith
发明人： Jerry Mahabub , Stephan A. Bernsee , Gary Smith
IPC分类号： H04R5/00 , H04S5/00 , H04S3/00 , H04S1/00
CPC分类号： H04S5/00 , H04R2499/13 , H04S1/00 , H04S3/00 , H04S2400/03 , H04S2420/01
摘要： Methods and apparatus are disclosed for processing an audio sound source to create four-dimensional spatialized sound. A virtual sound source may be moved along a path in three-dimensional space over a specified time period to achieve four-dimensional sound localization. The various embodiments described herein provide methods and systems for converting existing mono, 2-channel and/or multi-channel audio signals into spatialized audio signals have two or more audio channels. The incoming audio signals may be down-mixed, up-mixed or otherwise translated into fewer, greater or the same number of audio channels. The various embodiments also describe methods, systems and apparatus for generating low frequency effect and center channel signals from incoming audio signals having one or more channels.
摘要翻译：公开了用于处理音频声源以产生四维空间化声音的方法和装置。虚拟声源可以在三维空间中的路径上移动规定的时间段以实现四维声音定位。本文描述的各种实施例提供了用于将现有的单声道，2声道和/或多声道音频信号转换为具有两个或更多个音频通道的空间化音频信号的方法和系统。传入的音频信号可以被混合，混合或以其他方式转换成更少，更大或相同数量的音频通道。各种实施例还描述了用于从具有一个或多个信道的输入音频信号产生低频效应和中心信道信号的方法，系统和装置。

9. 发明授权

US08354131B2 Microwavable food products 有权
标题翻译：微波炉食品
公开(公告)号：US08354131B2
公开(公告)日：2013-01-15
申请号：US12265545
申请日：2008-11-05
申请人： Renee Gan , Gary Smith , Ya-yu Pai , Keith Forneck
发明人： Renee Gan , Gary Smith , Ya-yu Pai , Keith Forneck
IPC分类号： B65D85/00
CPC分类号： A21D17/006 , A21D2/183 , A21D2/188 , A21D8/042 , A21D10/02 , A21D13/32 , A21D15/00 , A21D15/02 , B65D81/3453 , B65D2581/3405 , B65D2581/3494
摘要： The packaging system includes a first food product sealed within an inner wrapper, a second food product positioned within a tray and spacing the first food product from the tray, and an outer wrapper sealing the first food product, sealed within the inner wrapper, the second food product and the tray therein. A shield is disposed on the tray and is in contact with more than one surface of the second food product. Prior to microwave heating, the inner and outer wrapper are removed.
摘要翻译：包装系统包括密封在内包装内的第一食品，定位在托盘内并将第一食品与托盘间隔开的第二食品，以及密封第一食品的外包装，密封在内包装内，第二食品食品和托盘。屏蔽件设置在托盘上并与第二食品的多于一个的表面接触。在微波加热之前，内外包装被去除。

10. 发明授权

US08124149B2 Microwavable food products 有权
公开(公告)号：US08124149B2
公开(公告)日：2012-02-28
申请号：US12265545
申请日：2008-11-05
申请人： Renee Gan , Gary Smith , Ya-yu Pai , Keith Forneck
发明人： Renee Gan , Gary Smith , Ya-yu Pai , Keith Forneck
IPC分类号： B65D85/00
摘要： The packaging system includes a first food product sealed within an inner wrapper, a second food product positioned within a tray and spacing the first food product from the tray, and an outer wrapper sealing the first food product, sealed within the inner wrapper, the second food product and the tray therein. A shield is disposed on the tray and is in contact with more than one surface of the second food product. Prior to microwave heating, the inner and outer wrapper are removed.

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