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    • 4. 发明授权
    • Uracil derivatives
    • 尿嘧啶衍生物
    • US4267326A
    • 1981-05-12
    • US15149
    • 1979-02-26
    • Shoichiro OzakiYoshimasa IkeKatsutoshi IshikawaHaruki Mori
    • Shoichiro OzakiYoshimasa IkeKatsutoshi IshikawaHaruki Mori
    • C07D239/545A61K31/495A61K31/505A61K31/513A61P35/00C07D239/54C07D239/553
    • C07D239/553
    • New uracil derivatives of the general formula: ##STR1## wherein R.sup.1 stands for a hydrogen atom or a grouping of the formula: ##STR2## R.sup.2 for a hydrogen atom, an alkyl group or a phenyl group and R.sup.3 for an alkyl group or a phenyl group, with the proviso that when both R.sup.1 and R.sup.2 stand for a hydrogen atom, R.sup.3 stands for a phenyl group or a straight chain alkyl group with 3.about.11 carbon atoms, that when R.sup.1 stands for a hydrogen atom and R.sup.2 for methyl group, R.sup.3 stands for an alkyl group with at least 2 carbon atoms or a phenyl group, and that when R.sup.1 stands for a hydrogen atom and R.sup.3 for methyl group, R.sup.2 stands for an alkyl group with at least 2 carbon atoms or a phenyl group. These uracil derivatives are prepared by reacting 5-fluorouracil with an .alpha.-haloalkyl carboxylate or with an aldehyde diacylate or by hydrolyzing a 1,3-bis(acyloxymethyl)-5-fluorouracil with an acid or alkali. These uracil derivatives are useful as improved anti-tumor agents especially for oral administration and injection.
    • 其中R1代表氢原子的新的尿嘧啶衍生物或氢原子,烷基或苯基基团的下式的分子式:R 2,烷基或苯基的R 3 基团,条件是当R1和R2均表示氢原子时,R3表示具有3个碳原子的苯基或直链烷基,当R1表示氢原子且R2表示甲基时, R3表示具有至少2个碳原子的烷基或苯基,当R1表示氢原子且R3表示甲基时,R2表示具有至少2个碳原子的烷基或苯基。 这些尿嘧啶衍生物通过5-氟尿嘧啶与α-卤代烷基羧酸酯或二醛酸醛反应或通过用酸或碱水解1,3-双(酰氧基甲基)-5-氟尿嘧啶来制备。 这些尿嘧啶衍生物可用作改进的抗肿瘤剂,特别是用于口服给药和注射。
    • 6. 发明申请
    • ESTERIFICATION REACTION PRODUCT, GELLING AGENT CONTAINING THE PRODUCT, AND COSMETIC PREPARATION CONTAINING THEM
    • 产品反应产品,含有产品的胶凝剂,以及包含它们的化妆品制剂
    • US20090324519A1
    • 2009-12-31
    • US12309687
    • 2007-07-20
    • Haruki Mori
    • Haruki Mori
    • A61K8/72A61Q1/06A61Q17/04A61Q5/12A61Q5/02A61Q19/10A61Q1/02C08G63/48A61K47/34A61K8/06
    • A61K8/85A61K8/891A61Q1/02A61Q1/06A61Q5/00A61Q17/04A61Q19/10C08G63/48
    • Disclosed is an esterification reaction product which is capable of gelling both an oil agent and a cyclic silicone or a volatile dimethylpolysiloxane, or both an oil agent and a nonvolatile dimethylpolysiloxane. Also disclosed are a gelling agent contacting the esterification reaction product, and a cosmetic preparation containing the esterification reaction product or the gelling product and having an excellent feeling of use. Specifically, the cosmetic preparation contains, as a gelling agent, an esterification reaction product which is obtained by esterifying a component A that is a polyhydric alcohol or a condensate thereof, a component B that is a saturated dibasic acid having 10-28 carbon atoms, a component C that is a linear saturated fatty acid having 16-28 carbon atoms, and a component D that is a branched saturated fatty acid having 8-28 carbon atoms at a blending ratio (component A: component B) of 1.0 mole:0.10-0.20 mole.
    • 公开了能够使油剂和环状硅氧烷或挥发性二甲基聚硅氧烷或油剂和不挥发性二甲基聚硅氧烷两者凝胶化的酯化反应产物。 还公开了与酯化反应产物接触的胶凝剂和含有酯化反应产物或胶凝产物并具有优异使用感的化妆品。 具体地说,化妆品中含有通过酯化作为多元醇或其缩合物的成分A,作为碳原子数为10〜28的饱和二元酸的成分B而得到的酯化反应产物作为胶凝剂, 作为具有16-28个碳原子的直链饱和脂肪酸的组分C和具有8-28个碳原子的支链饱和脂肪酸的组分D(组分A:组分B)为1.0摩尔:0.10 -0.20摩尔。
    • 10. 发明授权
    • Color liquid crystal display device
    • 彩色液晶显示装置
    • US06181309B2
    • 2001-01-30
    • US09065729
    • 1998-04-24
    • Haruki MoriMasao Ozeki
    • Haruki MoriMasao Ozeki
    • G09G336
    • G09G3/3622G02F1/1397
    • A reflective type STN color liquid crystal display device having polarizers a liquid crystal layer a birefringent plate, an absorbing axis of upper polarizer, an absorbing axis of lower polarizer. Also include is the direction of a long axis of a liquid crystal molecule at an upper side of the liquid crystal layer, the direction of a long axis of a liquid crystal molecule at a lower side, a slow axis of birefringent plate, scanning electrodes of an N number, and data electrodes. Further BR≦PN−2 is satisfied when PN=N0.5+1 and bias value BR=(Vr+Vc)/(Vc).
    • 具有偏振器的反射型STN彩色液晶显示装置,液晶层为双折射板,上偏振片的吸收轴,下偏振片的吸收轴。 还包括在液晶层上侧的液晶分子的长轴方向,下侧的液晶分子的长轴方向,双折射板的慢轴,扫描电极 N个数字和数据电极。 当PN = N0.5 + 1和偏置值BR =(Vr + Vc)/(Vc)时,满足BR <= PN-2。