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1. 发明申请

US20080108123A1 MAGNETIC SUBSTANCE-BIOSUBSTANCE COMPLEX STRUCTURE, PEPTIDE FRAGMENT CAPABLE OF LINKING TO MAGNETIC SUBSTANCE AND GENE THEREFOR, AND PROCESS FOR PRODUCING THE COMPLEX STRUCTURE 审中-公开
标题翻译：磁性物质 - 生物传感器复合结构，能够连接到磁性物质及其基因的肽片段，以及用于生产复合结构的方法
公开(公告)号：US20080108123A1
公开(公告)日：2008-05-08
申请号：US11937611
申请日：2007-11-09
申请人： Takeshi Imamura , Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Tsutomu Honma , Akiko Tsuchitani
发明人： Takeshi Imamura , Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Tsutomu Honma , Akiko Tsuchitani
IPC分类号： C12N9/00 , C07H23/00 , C11C3/00 , C07K1/00 , C07H21/04 , C07K14/00
CPC分类号： C12N9/1025 , C07K2319/00 , C12N11/06 , C12N11/14 , C12N15/1013 , G01N33/54326 , G01N33/54353 , Y10S530/811
摘要： A magnetic substance-biosubstance complex structure comprises a magnetic substance-containing carrier and a biosubstance immobilized on the carrier, the biosubstance being immobilized through a spacer comprising an amino acid sequence on a surface of the carrier.
摘要翻译：磁性物质 - 生物物质复合物结构包括含磁性物质的载体和固定在载体上的生物体，生物质通过包含载体表面上的氨基酸序列的间隔物固定化。

2. 发明授权

US5803664A Process for remediating soil 失效
标题翻译：修复土壤的过程
公开(公告)号：US5803664A
公开(公告)日：1998-09-08
申请号：US768585
申请日：1996-12-18
申请人： Yuji Kawabata , Tetsuya Yano , Yoshiyuki Touge , Shinya Kozaki , Takeshi Imamura , Masatoshi Iio , Michiyo Suzuki , Yuri Senshu
发明人： Yuji Kawabata , Tetsuya Yano , Yoshiyuki Touge , Shinya Kozaki , Takeshi Imamura , Masatoshi Iio , Michiyo Suzuki , Yuri Senshu
IPC分类号： E02D3/12 , A62D3/00 , A62D3/02 , B09C1/10 , C09K17/32 , C09K103/00 , C12N1/00 , B09B1/10
CPC分类号： B09C1/10 , B09C2101/00
摘要： A process for remedying polluted soil which comprises the steps of injecting a liquid agent containing a microorganism into the polluted soil, and injecting a gas into a region wherein the water content of the soil became 0.6 or more times its saturation water content after the injection of the liquid agent. Using this method bioremediation of contaminated soil can be economically and efficiently carried out.
摘要翻译：一种补救污染土壤的方法，包括以下步骤：将含有微生物的液体试剂注入污染土壤中，并将气体注入到土壤中的含水量成为其注入后的饱和含水量的0.6倍或更多倍的区域液体剂。使用这种方法可以经济有效地进行污染土壤的生物修复。

3. 发明授权

US07354995B2 Magnetic substance-biosubstance complex structure, peptide fragment capable of linking to magnetic substance and gene therefor, and process for producing the complex structure 失效
标题翻译：磁性物质 - 生物体复合结构，能够与磁性物质连接的肽片段及其基因，以及复合结构体的制造方法
公开(公告)号：US07354995B2
公开(公告)日：2008-04-08
申请号：US10546404
申请日：2004-04-30
申请人： Takeshi Imamura , Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Tsutomu Honma , Akiko Tsuchitani
发明人： Takeshi Imamura , Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Tsutomu Honma , Akiko Tsuchitani
IPC分类号： C07K7/08 , C07K17/14
CPC分类号： C12N9/1025 , C07K2319/00 , C12N11/06 , C12N11/14 , C12N15/1013 , G01N33/54326 , G01N33/54353 , Y10S530/811
摘要： A magnetic substance-biosubstance complex structure comprises a magnetic substance-containing carrier and a bio-substance immobilized on the carrier, the biosubstance being immobilized through a spacer comprising an amino acid sequence on a surface of the carrier.
摘要翻译：磁性物质 - 生物物质复合结构包括含磁性物质的载体和固定在载体上的生物物质，生物质通过载体表面上的氨基酸序列的间隔物固定化。

4. 发明申请

US20070054315A1 Magnetic substance-biosubstance complex structure, peptide fragment capable of linking to magnetic substance and gene therefor, and process for producing the complex structure 失效
标题翻译：磁性物质 - 生物体复合结构，能够与磁性物质连接的肽片段及其基因，以及复合结构体的制造方法
公开(公告)号：US20070054315A1
公开(公告)日：2007-03-08
申请号：US10546404
申请日：2004-04-30
申请人： Takeshi Imamura , Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Tsutomu Honma , Akiko Tsuchitani
发明人： Takeshi Imamura , Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Tsutomu Honma , Akiko Tsuchitani
IPC分类号： C40B40/10 , C40B40/04 , C07H21/04 , C12P21/06 , C12P7/62 , C12N9/18 , C12N15/74
CPC分类号： C12N9/1025 , C07K2319/00 , C12N11/06 , C12N11/14 , C12N15/1013 , G01N33/54326 , G01N33/54353 , Y10S530/811
摘要： A magnetic substance-biosubstance complex structure comprises a magnetic substance-containing carrier and a bio-substance immobilized on the carrier, the biosubstance being immobilized through a spacer comprising an amino acid sequence on a surface of the carrier.
摘要翻译：磁性物质 - 生物物质复合结构包括含磁性物质的载体和固定在载体上的生物物质，生物质通过载体表面上的氨基酸序列的间隔物固定化。

5. 发明授权

US07135540B2 Polyhydroxyalkanoate copolymer including unit having bromo group in side chain and method for producing the same 失效
标题翻译：聚羟基链烷酸酯共聚物，包括在侧链中具有溴基的单元及其制备方法
公开(公告)号：US07135540B2
公开(公告)日：2006-11-14
申请号：US10359600
申请日：2003-02-07
申请人： Tsutomu Honma , Shinya Kozaki , Takeshi Imamura , Takashi Kenmoku , Tatsuki Fukui , Etsuko Sugawa , Tetsuya Yano
发明人： Tsutomu Honma , Shinya Kozaki , Takeshi Imamura , Takashi Kenmoku , Tatsuki Fukui , Etsuko Sugawa , Tetsuya Yano
IPC分类号： C08G63/02
CPC分类号： C12P7/625 , C08G63/6822 , C08G63/6882 , C12P11/00
摘要： The invention provides a polyhydroxyalkanoate having a bromo group in a unit and being thermally stable and capable of arbitrarily controlling physical properties, and a producing method thereof. According to the invention, there are provided a polyhydroxyalkanoate copolymer including a 3-hydroxy-ω-bromoalkanoic acid unit represented by a formula—[OCH((CH2)nBr)CH2C(O)]— (n=1 to 8) (1) and a unit represented by a formula —[OCH((CH2)mR)CH2C(O)]— (2) within a same molecule, and a method for producing a polyhydroxyalkanoate copolymer by microorganisms, utilizing a ω-bromoalkanoic acid represented by a formula Br(CH2)pCH2CH2COOH (p=1 to 8) (20) and a compound represented by a formula R(CH2)qCH2CH2COOH (21) as raw materials.
摘要翻译：本发明提供一种具有溴基团并且是热稳定的并能够任意控制物理性能的聚羟基链烷酸酯及其制备方法。根据本发明，提供了一种包含由式 - [OCH（（CH 2）n）n Br表示的3-羟基-ω-溴代链烷酸单元的聚羟基链烷酸酯共聚物）CH 2 C（O）] - （n = 1-8）（1）和由式 - [OCH（（CH 2）2）（O）] - （2），以及通过微生物制备聚羟基链烷酸酯共聚物的方法，使用由以下化合物表示的ω-溴烷酸：式（Br 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 CH 2 COOH（p = 1〜8）（20 ）和由式R（CH 2 CH 2）q CH 2 CH 2 COOH（21）表示的化合物作为原料。

6. 发明授权

US06660516B1 Method for culturing a microorganism and promoting microbial growth and metabolism 失效
标题翻译：培养微生物并促进微生物生长和代谢的方法
公开(公告)号：US06660516B1
公开(公告)日：2003-12-09
申请号：US09025424
申请日：1998-02-18
申请人： Takeshi Imamura , Yasutsugu Yamada , Tetsuya Yano , Akira Kuriyama , Shinya Kozaki
发明人： Takeshi Imamura , Yasutsugu Yamada , Tetsuya Yano , Akira Kuriyama , Shinya Kozaki
IPC分类号： B09B300
CPC分类号： C12N1/38 , C02F1/4618 , C02F3/34 , C02F2209/04 , C02F2209/06 , C12R1/19 , Y10S435/822 , Y10S435/849
摘要： A method is provided for culturing a microorganism in a culture medium containing a carbon source and an electrolyzed water containing not more than 0.4 ppm chlorine produced during electrolyzing water containing an electrolyte in an electrolytic cell. The culture medium may also contain a carbon source and an acidic water having a pH value of 1-4 and a redox potential from 800 mV to 1500 mV. The acidic water is obtained by electrolysis of water in an electrolytic cell. Further, the culture medium may contain a carbon source and an alkaline water having a pH value of 10-13 and a redox potential from −1000 mV to 800 mV. The alkaline water is obtained by electrolysis of water in an electrolytic cell. The redox potential for the alkaline water is determined by the use of a platinum electrode as a working electrode and a silver-silver chloride electrode as a reference electrode. The microorganism may be selected from Escherichia coli, strain J1, strain JM2N, or an artificial recombinant. The microorganism can decompose a pollutant, such as phenol, toluene, cresol, trichlorethylene and dichloroethylene.
摘要翻译：提供了一种在含有碳源的培养基中培养微生物的方法，以及在电解槽中含有电解质中含有电解质的水中产生的含有不超过0.4ppm氯的电解水。培养基也可以含有碳源和pH值为1-4，氧化还原电位为800mV〜1500mV的酸性水。酸性水通过在电解池中电解水而获得。此外，培养基可以含有碳源和pH值为10-13，氧化还原电位为-1000mV至800mV的碱性水。碱性水通过在电解槽中电解电解而获得。碱性水的氧化还原电位通过使用铂电极作为工作电极和银 - 氯化银电极作为参比电极来确定。微生物可以选自大肠杆菌，菌株J1，菌株JM2N，或人工重组体。微生物可以分解苯酚，甲苯，甲酚，三氯乙烯和二氯乙烯等污染物。

7. 发明授权

US5807736A Method for biodegradation of aromatic and chlorinated compounds using microorganism strain FERM BP-5102 失效
标题翻译：使用微生物菌株FERM BP-5102生物降解芳香族和氯化化合物的方法
公开(公告)号：US5807736A
公开(公告)日：1998-09-15
申请号：US454515
申请日：1995-05-30
申请人： Shinya Kozaki , Kinya Kato , Tetsuya Yano , Takeshi Imamura
发明人： Shinya Kozaki , Kinya Kato , Tetsuya Yano , Takeshi Imamura
IPC分类号： A62D3/00 , A62D3/02 , B09C1/10 , C02F3/34 , C02F11/02 , C12N1/20 , C12R1/15 , C02F3/00 , C12N1/00 , D06M16/00
CPC分类号： C12R1/15 , C02F3/34 , Y10S435/821 , Y10S435/822 , Y10S435/843
摘要： A bacterial strain J1 (FERM BP-5102) which can effectively degrade aromatic compounds and/or chlorinated organic compounds such as trichloroethylene (TCE) is disclosed. Also the degradation occurs at a lower temperature such as 15.degree.. Further, a method for purifying waste water, soil or a gas polluted with the above chemical compounds utilizing the bacterium is disclosed.
摘要翻译：公开了能够有效降解芳族化合物和/或氯化有机化合物如三氯乙烯（TCE）的细菌菌株J1（FERM BP-5102）。此外，降解发生在较低温度如15℃。此外，公开了利用细菌净化上述化合物污染的废水，土壤或气体的方法。

8. 发明申请

US20090029423A1 METHOD FOR SEPARATING TARGET COMPONENT 审中-公开
标题翻译：分离目标组件的方法
公开(公告)号：US20090029423A1
公开(公告)日：2009-01-29
申请号：US12201338
申请日：2008-08-29
申请人： Takeshi Imamura , Tetsuya Yano , Tsutomu Honma , Shinya Kozaki , Tsuyoshi Nomoto , Akiko Tsuchitani
发明人： Takeshi Imamura , Tetsuya Yano , Tsutomu Honma , Shinya Kozaki , Tsuyoshi Nomoto , Akiko Tsuchitani
IPC分类号： C12P19/34 , C12P7/42
CPC分类号： C12N9/93 , C07K2319/23 , C09D167/04 , C12N11/08 , C12P7/625 , G01N33/54326 , G01N33/54393 , G01N2333/21 , G01N2333/245
摘要： A construct in which at least a part of the magnetic material is coated with a polyhydroxyalkanoate (PHA), and a method for producing a construct by immobilizing a PHA synthesizing enzyme on the surface of the magnetic material, thereby biosynthesizing and coating a PHA.
摘要翻译：其中至少一部分磁性材料涂覆有聚羟基链烷酸酯（PHA）的构建体，以及通过将PHA合成酶固定在磁性材料的表面上从而生物合成和涂覆PHA的制造方法。

9. 发明申请

US20070027291A1 Structure and method for producing structure, toner containing structure, image forming method and device using toner 审中-公开
标题翻译：用于生产结构的结构和方法，含调色剂的结构，成像方法和使用调色剂的装置
公开(公告)号：US20070027291A1
公开(公告)日：2007-02-01
申请号：US10534040
申请日：2004-04-30
申请人： Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Takeshi Imamura , Tsutomu Honma
发明人： Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Takeshi Imamura , Tsutomu Honma
IPC分类号： G03G9/00 , C08G67/00 , C08G63/00 , C08G69/00
CPC分类号： C12N9/93 , C07K2319/23 , C09D167/04 , C12N11/08 , C12P7/625 , G01N33/54326 , G01N33/54393 , G01N2333/21 , G01N2333/245
摘要： A structure, comprising a base material, coated with polymer which can be compatible with reduced load against environment and living organisms and various functionalities is provided. The base material is covered with polyhydroxyalkanoate (PHA). The invention also relates to a method for production of the structure comprising immobilizing the enzyme which synthesize PHA on the surface of the base material, biosynthesizing the PHA and coating the base material. The invention also provides toner containing such the structure and production thereof. Further, the invention relates to an image forming method comprising forming the image by providing such toner to the medium to be recorded.
摘要翻译：提供了一种结构，其包括涂覆有聚合物的基材，该聚合物可以与降低的环境负荷和生物体相容并具有各种功能。基材用聚羟基链烷酸酯（PHA）覆盖。本发明还涉及一种生产该结构的方法，其包括将在基材表面上合成PHA的酶固定化，生物合成PHA并涂覆该基材。本发明还提供含有这种结构和其制备的调色剂。此外，本发明涉及一种图像形成方法，包括通过向要记录的介质提供这种调色剂来形成图像。

10. 发明申请

US20060263432A1 Polyhydroxyalkanoate-containing magnetic structure, and manufacturing method and use thereof 失效
公开(公告)号：US20060263432A1
公开(公告)日：2006-11-23
申请号：US10553221
申请日：2004-04-30
申请人： Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Takeshi Imamura , Tsutomu Honma
发明人： Tetsuya Yano , Tsuyoshi Nomoto , Shinya Kozaki , Takeshi Imamura , Tsutomu Honma
IPC分类号： A61K38/43 , A61K9/14
CPC分类号： A61K9/5094 , A61K49/226 , Y10T428/12014
摘要： A structure containing polyhydroxyalkanoate and a magnetic substance includes an external phase part containing polyhydroxyalkanoate and an internal phase part contained in the external phase part, at least one of the external phase part and the internal phase part containing a magnetic substance. Accordingly, provided is a microcapsule, which can be suitably used for formation of an active ingredient of a sustained release pharmaceutical preparation or an ultrasonic contrast agent.

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