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1. 发明申请

US20070206097A1 Image acquiring apparatus, image acquiring method, and image acquiring program 有权
标题翻译：图像获取装置，图像获取方法和图像获取程序
公开(公告)号：US20070206097A1
公开(公告)日：2007-09-06
申请号：US11477822
申请日：2006-06-30
申请人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa , Jeremy Cooke
发明人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa , Jeremy Cooke
IPC分类号： H04N5/225
CPC分类号： G02B21/367
摘要： In acquisition of a micro image of a sample S by a micro image acquiring unit 30, when a plurality of image acquiring ranges are set for the sample S as an object of image acquisition, a plurality of corresponding focus information are set, and furthermore, when a plurality of partial images acquired by scanning the sample S by the micro image acquiring unit 30 include a partial image including mixing of a plurality of image acquiring ranges, the focus information is switched in the middle of scanning of the partial image. With such a structure, even when a plurality of objects are contained in the sample S, images of the respective objects can be preferably acquired. Thereby, an image acquiring apparatus, an image acquiring method, and an image acquiring program which are capable of preferably acquiring images of a plurality of objects are realized even when the plurality of objects are contained in a sample S.
摘要翻译：在通过微图像获取单元30获取样本S的微图像时，当为作为图像获取对象的样本S设置多个图像采集范围时，设置多个相应的焦点信息，此外，当通过微图像获取单元30扫描样本S获取的多个部分图像包括包括多个图像获取范围的混合的部分图像时，在部分图像的扫描中间切换焦点信息。通过这样的结构，即使在样本S中包含多个物体，也可以优选获得各个物体的图像。因此，即使当多个对象被包含在样本S中时，也能够实现能够优选地获取多个对象的图像的图像获取装置，图像获取方法和图像获取程序。

2. 发明授权

US07978898B2 Image acquiring apparatus, image acquiring method, and image acquiring program 有权
标题翻译：图像获取装置，图像获取方法和图像获取程序
公开(公告)号：US07978898B2
公开(公告)日：2011-07-12
申请号：US12857110
申请日：2010-08-16
申请人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa , Jeremy Cooke
发明人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa , Jeremy Cooke
IPC分类号： G06K9/00
CPC分类号： G02B21/367
摘要： In acquisition of a micro image of a sample by a micro image acquiring unit, when a plurality of image acquiring ranges are set for the sample as an object of image acquisition, a plurality of corresponding focus information are set, and furthermore, when a plurality of partial images acquired by scanning the sample by the micro image acquiring unit include a partial image including mixing of a plurality of image acquiring ranges, the focus information is switched in the middle of scanning of the partial image. With such a structure, even when a plurality of objects are contained in the sample, images of the respective objects can be preferably acquired. Thereby, an image acquiring apparatus, an image acquiring method, and an image acquiring program which are capable of preferably acquiring images of a plurality of objects are realized even when the plurality of objects are contained in a sample.
摘要翻译：在通过微图像获取单元获取样本的微图像时，当为样本设置多个图像采集范围作为图像获取对象时，设置多个对应的焦点信息，此外，当多个通过由微图像获取单元扫描样本而获取的部分图像包括包括多个图像获取范围的混合的部分图像，在部分图像的扫描中间切换焦点信息。利用这种结构，即使在样本中包含多个对象，也可以优选地获取各个对象的图像。因此，即使当多个对象被包含在样本中时，也能够实现能够优选地获取多个对象的图像的图像获取装置，图像获取方法和图像获取程序。

3. 发明授权

US08422127B2 Microscopic image capturing device 有权
标题翻译：显微镜摄像装置
公开(公告)号：US08422127B2
公开(公告)日：2013-04-16
申请号：US11886255
申请日：2006-03-17
申请人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa
发明人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa
IPC分类号： G02B21/00
CPC分类号： G02B21/241 , G02B21/26 , G02B21/365
摘要： The present invention relates to a microscopic image capturing apparatus having a structure that, in scanning an imageable area of an imaging unit in a predetermined direction in an imaging object area, in which a sample is present, can reliably set a focal point of the imaging unit on each imaging position set inside the imaging object area regardless of the type of focusing actuator. The microscopic image capturing apparatus has a sample setting stage having a sample setting surface that is inclined with respect to a scan plane orthogonal to an optical axis of an objective lens. By moving the sample setting stage along the scan plane such that the distance in the optical axis direction between the imaging unit and the sample setting surface varies monotonously, the focal point position of the imaging unit is adjusted in only one direction along the optical axis of the objective lens.
摘要翻译：本发明涉及一种显微图像拍摄装置，其特征在于，在成像对象区域内，在成像对象区域内，在成像单元的预定方向的可成像区域中进行扫描时，能够可靠地设定成像的焦点在成像对象区域内设置的每个成像位置上的单位，而与聚焦致动器的类型无关。微观图像拍摄装置具有样品设定台，该样品设定台具有相对于与物镜的光轴正交的扫描面倾斜的样品设定面。通过沿着扫描平面移动样品设定台，使得成像单元和样品设定面之间的光轴方向上的距离单调变化，则成像单元的焦点位置仅在沿着物镜。

4. 发明授权

US07801352B2 Image acquiring apparatus, image acquiring method, and image acquiring program 有权
标题翻译：图像获取装置，图像获取方法和图像获取程序
公开(公告)号：US07801352B2
公开(公告)日：2010-09-21
申请号：US11477822
申请日：2006-06-30
申请人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa , Jeremy Cooke
发明人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa , Jeremy Cooke
IPC分类号： G06K9/00
CPC分类号： G02B21/367
摘要： In acquisition of a micro image of a sample S by a micro image acquiring unit, when a plurality of image acquiring ranges are set for the sample S as an object of image acquisition, a plurality of corresponding focus information are set, and furthermore, when a plurality of partial images acquired by scanning the sample S by the micro image acquiring unit include a partial image including mixing of a plurality of image acquiring ranges, the focus information is switched in the middle of scanning of the partial image. With such a structure, even when a plurality of objects are contained in the sample S, images of the respective objects can be preferably acquired. Thereby, an image acquiring apparatus, an image acquiring method, and an image acquiring program which are capable of preferably acquiring images of a plurality of objects are realized even when the plurality of objects are contained in a sample S.
摘要翻译：在通过微图像获取单元获取样本S的微图像时，当为作为图像获取对象的样本S设置多个图像获取范围时，设置多个对应的焦点信息，此外，当通过由微图像获取单元扫描样本S获取的多个部分图像包括包括多个图像获取范围的混合的部分图像，在部分图像的扫描中间切换焦点信息。通过这样的结构，即使在样本S中包含多个物体，也可以优选获得各个物体的图像。因此，即使当多个对象被包含在样本S中时，也能够实现能够优选地获取多个对象的图像的图像获取装置，图像获取方法和图像获取程序。

5. 发明申请

US20090002811A1 Microscopic Image Capturing Device 有权
标题翻译：显微图像捕获装置
公开(公告)号：US20090002811A1
公开(公告)日：2009-01-01
申请号：US11886255
申请日：2006-03-17
申请人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa
发明人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa
IPC分类号： G02B21/26 , G02B21/36
CPC分类号： G02B21/241 , G02B21/26 , G02B21/365
摘要： The present invention relates to a microscopic image capturing apparatus having a structure that, in scanning an imageable area of an imaging unit in a predetermined direction in an imaging object area, in which a sample is present, can reliably set a focal point of the imaging unit on each imaging position set inside the imaging object area regardless of the type of focusing actuator. The microscopic image capturing apparatus has a sample setting stage having a sample setting surface that is inclined with respect to a scan plane orthogonal to an optical axis of an objective lens. By moving the sample setting stage, which has such a sample setting surface, along the scan plane in a manner such that the distance in the optical axis direction between the imaging unit and the sample setting surface varies monotonously, the focal point position of the imaging unit is adjusted in only one direction along the optical axis of the objective lens. In this case, even when a stepping motor is applied as the focusing actuator, the occurrence of lost motion in a driving system based on the stepping motor is prevented reliably and the focal point of the imaging unit can be set reliably on each imaging position set inside the imaging object area.
摘要翻译：本发明涉及一种显微图像拍摄装置，其特征在于，在成像对象区域内，在成像对象区域内，在成像单元的预定方向的可成像区域中进行扫描时，能够可靠地设定成像的焦点在成像对象区域内设置的每个成像位置上的单位，而与聚焦致动器的类型无关。微观图像拍摄装置具有样品设定台，该样品设定台具有相对于与物镜的光轴正交的扫描面倾斜的样品设定面。通过沿着扫描平面移动具有这样的样品设定面的样品设定台，使得成像单元和样品设定面之间的光轴方向的距离单调变化，成像的焦点位置单元沿着物镜的光轴在一个方向上被调整。在这种情况下，即使施加步进电机作为聚焦致动器，也可以可靠地防止基于步进电动机的驱动系统中的运动的发生，并且能够可靠地将摄像部的焦点设定在各摄像位置组在成像对象区域内。

6. 发明申请

US20080283722A1 Autofocus Device and Microscope Using the Same 审中-公开
标题翻译：自动对焦设备和显微镜使用相同
公开(公告)号：US20080283722A1
公开(公告)日：2008-11-20
申请号：US11658499
申请日：2005-07-20
申请人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa
发明人： Shigeru Uchiyama , Takayuki Inoue , Masatoshi Okugawa
IPC分类号： G02B27/64 , G02B21/00
CPC分类号： G02B21/367 , G02B7/38 , H04N5/23212
摘要： A microscope apparatus 1A is formed with a CCD camera 30 that acquires an image of a sample S, a light guiding optical system 20 that guides an optical image of the sample S to the camera 30, an optical system driving section 25 that drives the camera 30 and the optical system 20 to change a focal position on the sample S in a z-axis direction, and a control device 50 that includes a focal point control section 51. The focal point control section 51 calculates a first focal point measurement value from a plurality of images acquired by a first focal point measurement that is executed while continuously changing the focal position in one direction, calculates a second focal point measurement value from a plurality of images acquired by a second focal point measurement that is executed while continuously changing the focal position in a direction opposite that of the first focal point measurement, and determines an in-focus position for the sample S based on the first and second focal point measurement values. This realizes an automatic focusing device that is capable of accurately determining an in-focus position in a short time and a microscope apparatus using the same.
摘要翻译：显微镜装置1A形成有获取样本S的图像的CCD照相机30，将样本S的光学图像引导到照相机30的导光光学系统20，驱动照相机30的光学系统驱动部25 照相机30和光学系统20，以在z轴方向上改变样本S上的焦点位置，以及包括焦点控制部分51的控制装置50.焦点控制部分51计算第一焦点测量值从通过在一个方向连续地改变焦点位置而执行的第一焦点测量获取的多个图像中，从通过在连续变化时执行的第二焦点测量获得的多个图像计算第二焦点测量值在与第一焦点测量相反的方向上的焦点位置，并且基于第一和第二焦点p确定样本S的对焦位置软膏测量值。这实现了能够在短时间内精确地确定对焦位置的自动聚焦装置和使用其的显微镜装置。

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