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    • 5. 发明授权
    • Automatic performance device for a keyboard instrument
    • 键盘乐器的自动演奏设备
    • US5210367A
    • 1993-05-11
    • US619297
    • 1990-11-28
    • Hanzou TaguchiShigeru MuramatsuKiyoshi Kawamura
    • Hanzou TaguchiShigeru MuramatsuKiyoshi Kawamura
    • G10F1/02
    • G10F1/02
    • An automatic performance device for a keyboard instrument such as piano, organ, cembalo and celesta includes operators such as keys and a pedal provided in a keyboard instrument for producing sounds, a target performance state designation unit for producing target performance information of the keyboard instrument, a real performance state detection circuit for detecting an operation state of the operators and producing a detection output, an actuator such as a solenoid for actuating the operators, and a control circuit for controlling the actuator. The control circuit detects in error between the detection output of the real performance state detection circuit and the target performance information, and generates an operator actuating signal by correcting the target performance information to eliminate the error and supplies the corrected operator actuating signal to the actuator.
    • 用于键盘乐器如钢琴,器官,cembalo和celesta的自动演奏装置包括用于产生声音的键盘乐器中提供的键和踏板等操作员,用于产生键盘乐器的目标演奏信息的目标演奏状态指定单元, 用于检测操作者的操作状态并产生检测输出的实际性能状态检测电路,用于致动操作者的诸如螺线管的致动器,以及用于控制致动器的控制电路。 控制电路在实际性能状态检测电路的检测输出与目标性能信息之间有误差地检测,并且通过校正目标性能信息来消除误差并产生操作者致动信号,并将修正的操作者致动信号提供给致动器。
    • 9. 发明授权
    • Quinolonecarboxylic acid compounds having 5-HT4 receptor agonistic activity
    • 具有5-HT 4受体激动活性的喹诺酮羧酸化合物
    • US07964727B2
    • 2011-06-21
    • US10595948
    • 2004-11-10
    • Tomoki KatoKiyoshi KawamuraMikio MoritaChikara Uchida
    • Tomoki KatoKiyoshi KawamuraMikio MoritaChikara Uchida
    • C07D221/02C07D215/00C07D413/00A01N43/40A01N43/42A61K31/435A61K31/44
    • C04B35/632C07D401/12C07D401/14C07D405/14
    • This invention provides a compound of the formula (I): wherein Het represents a heterocyclic group having one nitrogen atom, to which B binds directly, and from 4 to 7 carbon atoms, and said heterocyclic group being unsubstituted or substituted by 1 to 4 substituents independently selected from the group consisting of substituents α1; A represents an alkylene group having from 1 to 4 carbon atoms; B represents a covalent bond or an alkylene group having from 1 to 5 carbon atoms; R1 represents an isopropyl group, a n-propyl group or a cyclopentyl group; R2 represents a methyl group, a fluorine atom or a chlorine atom; R3 independently represents (i) an oxo group, a hydroxy group, an amino group, an alkylamino group or a carboxyl group; (ii) a cycloalkyl group having from 3 to 8 carbon atoms, and said cycloalkyl group being substituted by 1 to 5 substituents, or (iii) a heterocyclic group having from 3 to 8 atoms, and said heterocyclic group being unsubstituted or substituted by 1 to 5 substituents, and n is 1, 2 or 3, or a pharmaceutically acceptable salts thereof. These compounds have 5-HT4 receptor agonistic activity, and thus are useful for the treatment of gastroesophageal reflux disease, non-ulcer dyspepsia, functional dyspepsia, irritable bowel syndrome or the like in mammalian, especially humans.
    • 本发明提供式(I)化合物:其中Het表示具有一个氮原子的杂环基团,B直接与该碳原子结合,并且具有4至7个碳原子,所述杂环基团未被取代或被1至4个取代基取代 独立地选自取代基α1; A表示具有1至4个碳原子的亚烷基; B表示共价键或具有1至5个碳原子的亚烷基; R1表示异丙基,正丙基或环戊基; R2表示甲基,氟原子或氯原子; R3独立地表示(i)氧代基,羟基,氨基,烷基氨基或羧基; (ii)具有3至8个碳原子的环烷基,所述环烷基被1至5个取代基取代,或(iii)具有3至8个原子的杂环基,所述杂环基未被取代或被1 至5个取代基,n为1,2或3,或其药学上可接受的盐。 这些化合物具有5-HT 4受体激动活性,因此可用于治疗哺乳动物特别是人类的胃食管反流病,非溃疡性消化不良,功能性消化不良,肠易激综合征等。
    • 10. 发明授权
    • Polymer, crosslinked polymer, composition for solid polymer electrolyte, solid polymer electrolyte, and adhesive composition
    • 聚合物,交联聚合物,固体聚合物电解质的组合物,固体聚合物电解质和粘合剂组合物
    • US07645830B2
    • 2010-01-12
    • US11795783
    • 2006-01-18
    • Takeshi NiitaniMasato AmaikeMikiya ShimadaKiyoshi Kawamura
    • Takeshi NiitaniMasato AmaikeMikiya ShimadaKiyoshi Kawamura
    • C08F118/02C08L31/02C09J167/06
    • C08F293/005C08F290/06C08F293/00C08F297/02C08F297/026C08G18/6229C08L25/04C08L27/16C08L29/02C08L53/00C08L71/02C08L75/04C08L2205/05C08L2666/02C09J153/00H01M10/052H01M10/0565H01M2300/0082C08L2666/04
    • A polymer including a block chain A which is formed from a random copolymer containing a repeating unit (I) represented by the formula (I) wherein R1 to R3 each independently represents hydrogen or C1-10 hydrocarbon and R1 and R3 may bond to form a ring; R4a and R4b each independently represents hydrogen or methyl; R5 represents hydrogen, hydrocarbon, acyl, or silyl; and m represents any integer of 1 to 100 and when m is 2 or more and each R4a may be the same or different from one another and each R4b may be the same or different from one another; and a repeating unit (II) represented by the formula (II) wherein R6 and R8 each independently represents hydrogen or C1-10 hydrocarbon and R6 and R8 may bond to form a ring; R7 represents hydrogen, C1-10 hydrocarbon, hydroxyl, hydrocarbonoxy, carboxyl, acid anhydride, amino, ester, or an organic group having at least one functional group selected from the group consisting of hydroxyl, carboxyl, epoxy, acid anhydride, and amino; and R9 represents an organic group having at least one functional group selected from the group consisting of hydroxyl, carboxyl, epoxy, acid anhydride, and amino; and a block chain B having a repeating unit (III) represented by the formula (III) wherein R10 to R12 each independently represents hydrogen or C1-10 hydrocarbon and R13 represents aryl or heteroaryl; and wherein an arrangement order thereof is B, A, B.
    • 一种包含嵌段链A的聚合物,其由含有式(I)表示的重复单元(I)的无规共聚物形成,其中R 1至R 3各自独立地表示氢或C 1-10烃,并且R 1和R 3可以键合形成 环; R4a和R4b各自独立地表示氢或甲基; R5表示氢,烃,酰基或甲硅烷基; m表示1〜100的整数,m为2以上时,各R​​ 4a可以相同也可以不同,各R 4a可以相同也可以不同。 和由式(II)表示的重复单元(II),其中R6和R8各自独立地表示氢或C1-10烃,R6和R8可以键合形成环; R7表示氢,C1-10烃,羟基,烃氧基,羧基,酸酐,氨基,酯或具有至少一个选自羟基,羧基,环氧基,酸酐和氨基的官能团的有机基团; 并且R 9表示具有至少一个选自羟基,羧基,环氧基,酸酐和氨基的官能团的有机基团; 和具有由式(III)表示的重复单元(III)的嵌段链B,其中R10至R12各自独立地表示氢或C1-10烃,R13表示芳基或杂芳基; 其布置顺序为B,A,B。