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1. 发明授权

US06476462B2 MOS-type semiconductor device and method for making same 有权
标题翻译： MOS型半导体器件及其制造方法
公开(公告)号：US06476462B2
公开(公告)日：2002-11-05
申请号：US09732132
申请日：2000-12-07
申请人： Tatsuo Shimizu , Mieko Matsumura , Shigenobu Kimura , Yutaka Hirose , Yasuhiro Nishioka
发明人： Tatsuo Shimizu , Mieko Matsumura , Shigenobu Kimura , Yutaka Hirose , Yasuhiro Nishioka
IPC分类号： H01L2904
CPC分类号： H01L29/78 , H01L21/2007 , H01L21/28035 , H01L21/32055 , H01L29/045 , H01L29/16 , H01L29/4916
摘要： An MOS-type semiconductor device comprises two semiconductors separated by an insulator. The two semiconductors comprise monocrystal semiconductors, each having a crystallographic orientation with respect to the insulator (or other crystallographic/semiconductor property) different to the crystallographic orientation (or other respective property) of the other semiconductor. This arrangement of crystallographic orientations (and other crystallographic/semiconductor properties) can yield reduced unintended electron tunneling or current leakage through the insulator vis a vis a semiconductor device in which such an arrangement is not used. Methods for forming the MOS-type semiconductor devices of the invention are also provided.
摘要翻译： MOS型半导体器件包括由绝缘体隔开的两个半导体。两个半导体包括单晶半导体，它们各自具有与其他半导体的晶体取向（或其他相应的性质）不同的绝缘体的晶体取向（或其他晶体/半导体性质）。结晶取向（和其他晶体/半导体特性）的布置可以相对于不使用这种布置的半导体器件，可以减少意外的电子隧道效应或者通过绝缘体的电流泄漏。还提供了用于形成本发明的MOS型半导体器件的方法。

2. 发明授权

US5079551A .DELTA..SIGMA. digital-to-analog converter with bit grouping by significance for reducing feedback computation time 失效
标题翻译： DELTA SIGMA数模转换器，具有比特分组的意义，可减少反馈计算时间
公开(公告)号：US5079551A
公开(公告)日：1992-01-07
申请号：US550517
申请日：1990-07-10
申请人： Shigenobu Kimura , Masamitsu Yamamura
发明人： Shigenobu Kimura , Masamitsu Yamamura
IPC分类号： H03M3/02 , H03M7/00 , H03M7/32
CPC分类号： H03M7/304 , H03M7/3028
摘要： A .DELTA..SIGMA. modulation type 1-bit digital-to-analog conversion circuit includes an addition circuit for adding feedback digital data to input multi-bit digital data to provide results of addition, an integration circuit for integrating the results of addition provided by the addition circuit, a quantizer for quantizing output of the integration circuit to provide 1-bit digital data, and a circuit for providing analog data corresponding to the input multi-bit digital data on the basis of the 1-bit digital data. A bit of a predetermined order and bits of orders lower than the predetermined order in the feedback data are respectively made zero and bits of orders higher than the predetermined order only in the feedback data are added by the addition circuit. By feeding back only high order bits of feedback data for addition, the feedback addition is simplified and computation time thereby is shortened.
摘要翻译： DELTA SIGMA调制型1位数模转换电路包括用于将反馈数字数据添加到输入多位数字数据以提供结果的加法电路，用于对由加法提供的相加结果进行积分的积分电路电路，用于量化积分电路的输出以提供1位数字数据的量化器，以及用于基于1位数字数据提供与输入的多位数字数据相对应的模拟数据的电路。分别使反馈数据中的预定顺序和低于预定顺序的位的位为零，并且仅在反馈数据中比预定顺序高的位的位由加法电路相加。通过仅反馈高阶反馈数据的加法，简化了反馈加法，缩短了计算时间。

3. 发明授权

US06479049B1 Methods and compositions for the dry powder formulation of interferons 失效
标题翻译：干粉干粉制剂的方法和组成
公开(公告)号：US06479049B1
公开(公告)日：2002-11-12
申请号：US09506426
申请日：2000-02-17
申请人： Robert M. Platz , Shigenobu Kimura , Yu-ichiro Satoh , Linda C. Foster
发明人： Robert M. Platz , Shigenobu Kimura , Yu-ichiro Satoh , Linda C. Foster
IPC分类号： A61K3821
CPC分类号： A61K9/0075 , A61K9/1611 , A61K9/1623 , A61K9/1658 , A61K38/21 , A61K38/215 , Y02A50/395 , A61K2300/00
摘要： According to the present invention, methods and compositions are provided for spray-dried, interferon-based dry powder compositions, particularly interferon-beta. The compositions are useful for treating conditions in humans that are responsive to treatment with interferons. In particular, the methods of the present invention rely on spray drying to produce stable, high-potency dry powder formulations of interferons, including but not limited to IFN-beta. Surprisingly, it has been found that IFN can be prepared in high potency, dry powder formulations by spray drying. Such dry powder formulations find particular utility in the pulmonary delivery of IFN.
摘要翻译：根据本发明，提供了用于喷雾干燥的基于干扰素的干粉组合物，特别是干扰素-β的方法和组合物。该组合物可用于治疗对于用干扰素治疗有反应的人的病症。特别地，本发明的方法依赖于喷雾干燥以产生干扰素的稳定的高效干粉制剂，包括但不限于IFN-β。令人惊奇的是，已经发现通过喷雾干燥可以以高效，干粉制剂制备IFN。这种干粉制剂在IFN的肺部递送中具有特别的用途。

4. 发明授权

US5710823A Howling remover having cascade connected equalizers suppressing multiple noise peaks 失效
标题翻译：具有串联连接的均衡器的啸声去除器抑制多个噪声峰值
公开(公告)号：US5710823A
公开(公告)日：1998-01-20
申请号：US526771
申请日：1995-09-11
申请人： Yuichi Nagata , Satoshi Suzuki , Morito Yamada , Masao Yoshida , Mikio Kitano , Kiyoto Kuroiwa , Shigenobu Kimura
发明人： Yuichi Nagata , Satoshi Suzuki , Morito Yamada , Masao Yoshida , Mikio Kitano , Kiyoto Kuroiwa , Shigenobu Kimura
IPC分类号： G10K15/00 , H04R3/02 , H04R27/00
CPC分类号： H04R3/02
摘要： A howling prevention apparatus prevents a howling noise which is generated in a sound amplification system using a microphone and a loudspeaker. The howling prevention apparatus utilizes a plural number of first to n-th equalizers, which have a variable frequency response and which modulate an output of the microphone. A detector detects a frequency point at which a loop gain of the system reaches a peak while supplying a standard noise signal to the loudspeaker to produce a test sound and measuring the sound collected by the microphone through the series of the equalizers. A frequency response of the first equalizer is adjusted to suppress a noise peak at and around a frequency point detected by the detector. Then, a frequency response of the second equalizer is also adjusted to suppress a noise peak at and around another frequency point detected by the detector. Lastly, a frequency response of the n-th equalizer is adjusted by subsequently repeating the above setting procedure.
摘要翻译：啸叫防止装置防止在使用麦克风和扬声器的声音放大系统中产生的啸声。啸声预防装置利用具有可变频率响应并且调制麦克风的输出的多个第一至第N均衡器。检测器检测系统的环路增益达到峰值的频率点，同时向扬声器提供标准噪声信号以产生测试声音，并通过一系列均衡器测量由麦克风收集的声音。调整第一均衡器的频率响应以抑制由检测器检测的频点处和周围的噪声峰值。然后，还调整第二均衡器的频率响应，以抑制由检测器检测到的另一频率点处和周围的噪声峰值。最后，通过随后重复上述设置过程来调整第n个均衡器的频率响应。

5. 发明授权

US4274424A Device for automatically winding a blood pressure measuring cuff 失效
标题翻译：用于自动卷绕血压测量袖带的装置
公开(公告)号：US4274424A
公开(公告)日：1981-06-23
申请号：US46413
申请日：1979-06-07
申请人： Shigenobu Kimura , Yoshiro Kubo , Shigeru Bando , Akio Ose , Yukuo Kinoshita , Ryoichi Higashizono , Ikuo Hanamiya
发明人： Shigenobu Kimura , Yoshiro Kubo , Shigeru Bando , Akio Ose , Yukuo Kinoshita , Ryoichi Higashizono , Ikuo Hanamiya
IPC分类号： A61B5/022 , A61B5/02
CPC分类号： A61B5/02233
摘要： A device for automatically winding a blood pressure measuring cuff around a part of the human body. The cuff comprises a flexible band having a part fixedly secured to a surrounding member adapted to receive a part of the human body. The flexible band extends circumferentially along the inner wall of the surrounding member and having one end which is pulled circumferentially so as to be wound around a part of the human body. A flexible fluid chamber is provided along the inner wall of the flexible band to be interposed between the flexible band and a part of the human body. The flexible fluid chamber operates to apply a squeezing pressure to the part of the human body when a fluid is supplied to the flexible fluid chamber. A weight is connected to one end of the flexible band and a weight hoisting device is employed for hoisting the weight. A weight holder holds the weight at a predetermined hoisting position and a pulling force is caused by the weight when the holder is released and applied to the one end of the flexible band.
摘要翻译：一种用于在身体的一部分周围自动卷绕血压测量袖带的装置。袖带包括柔性带，其具有固定地固定到适于接收人体的一部分的周围构件的部分。柔性带沿着周围构件的内壁沿圆周方向延伸，并且具有沿周向拉动的一端，以便缠绕在人体的一部分上。柔性流体室沿着柔性带的内壁设置以插入在柔性带和人体的一部分之间。当向柔性流体室供应流体时，柔性流体室操作以向人体的一部分施加挤压压力。重物连接到柔性带的一端，并且采用重量提升装置来提升重量。重量保持器将重量保持在预定的提升位置，并且当保持器被释放并施加到柔性带的一端时由重量引起拉力。

6. 发明授权

US5019819A Digital-to-analog conversion circuit 失效
标题翻译：数模转换电路
公开(公告)号：US5019819A
公开(公告)日：1991-05-28
申请号：US514859
申请日：1990-04-26
申请人： Shigenobu Kimura
发明人： Shigenobu Kimura
IPC分类号： H03M1/08 , H03M3/02 , H03M7/02
CPC分类号： H03M7/02 , H03M3/368 , H03M3/502
摘要： A digital-to-analog conversion circuit capable of preventing a noise produced in a digital system from mixing in an analog output has an input circuit receiving a pulse-code modulated digital signal, a conversion circuit such as a noise shaping circuit for converting the pulse-code modulated digital signal to a pulse wave signal containing analog amplitude information in a time axis direction, a buffer circuit including an electrically insulated coupling circuit such as an optical coupling circuit for transmitting output of the conversion circuit, and an analog output circuit including an analog low-pass filter for delivering out output of the buffer circuit therethrough. A noise generated in a digital system is intercepted by the buffer circuit and is not transmitted further so that mixing of the noise in the analog output circuit is prevented.
摘要翻译：能够防止在数字系统中产生的噪声在模拟输出中混合的数模转换电路具有接收脉冲编码调制数字信号的输入电路，诸如噪声整形电路的转换电路，用于将脉冲编码调制数字信号到包含时间轴方向上的模拟幅度信息的脉波信号，缓冲电路包括电耦合电路，例如用于传输转换电路的输出的光耦合电路，以及模拟输出电路，包括：模拟低通滤波器，用于输出缓冲电路的输出。在数字系统中产生的噪声被缓冲电路截取，不会进一步传输，从而防止模拟输出电路中的噪声混合。

7. 发明授权

US4339826A Radio receiver having phase locked loop frequency synthesizer 失效
标题翻译：无线电接收机具有锁相环频率合成器
公开(公告)号：US4339826A
公开(公告)日：1982-07-13
申请号：US165091
申请日：1980-07-01
申请人： Minoru Ogita , Shigenobu Kimura
发明人： Minoru Ogita , Shigenobu Kimura
IPC分类号： H03L7/18 , H03J5/00 , H03J5/02 , H03J7/28 , H03L7/185 , H04B1/26
CPC分类号： H03L7/185 , H03J5/0281
摘要： A radio receiver comprises a frequency conversion circuit connected between a frequency-variable local oscillator and a divide-by-N programmable counter incorporated in a phase locked loop frequency synthesizer and adapted to continuously change the frequency to be divided by the programmable counter. Owing to the frequency conversion circuit, the local oscillator frequency is permitted to continuously change in the locked state of the phase locked loop so that the intermediate frequency offset adjustment of receivers, that is, the adjustment of the intermediate frequency of each receiver to the center frequency of an intermediate frequency filter used in the receiver can be made easily, and that a reception of such a broadcast station as having a carrier frequency which is not an integral multiple of a channel spacing frequency also can be made.
摘要翻译：无线电接收机包括连接在频率可变的本地振荡器和并入在锁相环频率合成器中的分频N可编程计数器之间的频率转换电路，并且适于连续地改变由可编程计数器划分的频率。由于频率转换电路，允许本地振荡器频率在锁相环的锁定状态下连续变化，使得接收机的中频偏移调整，即将每个接收机的中频调整到中心可以容易地使用在接收机中使用的中频滤波器的频率，并且可以进行具有不是信道间隔频率的整数倍的载波频率的这样的广播台的接收。

8. 发明授权

US4291414A Radio receiver operable in station search mode or station select mode 失效
标题翻译：无线电接收器可在台站搜索模式或台站选择模式下操作
公开(公告)号：US4291414A
公开(公告)日：1981-09-22
申请号：US145349
申请日：1980-04-30
申请人： Shigenobu Kimura
发明人： Shigenobu Kimura
IPC分类号： H03J5/02 , H03J7/06 , H03J7/28 , H03J7/26
CPC分类号： H03J7/06 , H03J5/0263 , H03J7/28
摘要： A radio receiver comprising a local oscillator, a first counter circuit for computing an algebraic sum of a number corresponding to an oscillating frequency of the local oscillator and a number corresponding to an intermediate frequency, the algebraic sum representing frequency information for a tuned input signal frequency of the receiver, a memory circuit for storing frequency information produced by the counter when the receiver is tuned to a broadcast station in a station search mode, a digital comparator for comparing the frequency information read out of the memory circuit with the frequency information of the counter in a station select mode, and a charge pump and lowpass filter responsive to the digital comparator to control a local oscillator frequency of the local oscillator so that the frequency information of the counter becomes coincident with the frequency information from the memory circuit. A second counter is provided for counting clock pulses in the station search mode. The output signal of the second counter is compared with the output signal of the first counter by the digital comparator. The station frequency information read out of the memory circuit in the station select mode may be programmed in the second counter.
摘要翻译：一种无线电接收机，包括本地振荡器，用于计算对应于本地振荡器的振荡频率的数字的代数和与对应于中频的数字的第一计数器电路，所述代数和表示调谐输入信号频率的频率信息接收机的存储电路，用于存储电台，用于当在台站搜索模式下将接收机调谐到广播站时存储由计数器产生的频率信息;数字比较器，用于将从存储器电路读出的频率信息与频率信息计数器在电台选择模式下，电荷泵和低通滤波器响应于数字比较器来控制本地振荡器的本地振荡器频率，使得计数器的频率信息与来自存储器电路的频率信息一致。第二个计数器被提供用于在站搜索模式下计数时钟脉冲。第二计数器的输出信号由数字比较器与第一计数器的输出信号进行比较。在站选择模式下从存储器电路读出的站频率信息可以在第二计数器中被编程。

9. 发明授权

US06231851B1 Methods and compositions for the dry powder formulation of interferons 失效
标题翻译：干粉干粉制剂的方法和组成
公开(公告)号：US06231851B1
公开(公告)日：2001-05-15
申请号：US08737724
申请日：1997-07-14
申请人： Robert M. Platz , Shigenobu Kimura , Yu-ichiro Satoh , Linda C. Foster
发明人： Robert M. Platz , Shigenobu Kimura , Yu-ichiro Satoh , Linda C. Foster
IPC分类号： A61K3821
CPC分类号： A61K9/0075 , A61K9/1611 , A61K9/1623 , A61K9/1658 , A61K38/21 , A61K38/215 , Y02A50/395 , A61K2300/00
摘要： According to the present invention, methods and compositions are provided for spray-dried, interferon-based dry powder compositions, particularly interferon-beta. The compositions are useful for treating conditions in humans that are responsive to treatment with interferons. In particular, the methods of the present invention rely on spray drying to produce stable, high-potency dry powder formulations of interferons, including but not limited to IFN-beta. Surprisingly, it has been found that IFN can be prepared in high potency, dry powder formulations by spray drying. Such dry powder formulations find particular utility in the pulmonary delivery of IFN.
摘要翻译：根据本发明，提供了用于喷雾干燥的基于干扰素的干粉组合物，特别是干扰素-β的方法和组合物。该组合物可用于治疗对于用干扰素治疗有反应的人的病症。特别地，本发明的方法依赖于喷雾干燥以产生干扰素的稳定的高效干粉制剂，包括但不限于IFN-β。令人惊奇的是，已经发现通过喷雾干燥可以以高效，干粉制剂制备IFN。这种干粉制剂在IFN的肺部递送中具有特别的用途。

10. 发明授权

US5729614A Howling remover composed of adjustable equalizers for attenuating complicated noise peaks 失效
标题翻译：啸声去除器由可调平衡器组成，用于衰减复杂的噪声峰值
公开(公告)号：US5729614A
公开(公告)日：1998-03-17
申请号：US526261
申请日：1995-09-11
申请人： Yuichi Nagata , Satoshi Suzuki , Morito Yamada , Masao Yoshida , Mikio Kitano , Kiyoto Kuroiwa , Shigenobu Kimura
发明人： Yuichi Nagata , Satoshi Suzuki , Morito Yamada , Masao Yoshida , Mikio Kitano , Kiyoto Kuroiwa , Shigenobu Kimura
IPC分类号： G10K15/04 , H04R3/02 , H04R27/00
CPC分类号： H04R3/02
摘要： In an apparatus for amplifying a sound while suppressing a howling noise, a microphone collects a sound and converts the collected sound into a corresponding input signal. An amplifier amplifies the input signal to generate the sound through a loudspeaker. A plurality of equalizers are interposed between the microphone and the amplifier, each equalizer having a variable attenuation frequency for attenuatively filtering the input signal around the attenuation frequency. Detection is conducted for detecting a plurality of noise spectrum peaks of the howling noise contained in the collected sound. Then, an adjustment is conducted adjusting respective variable attenuation frequencies of the plurality of the equalizers correspondingly to the plurality of the detected noise spectrum peaks to thereby remove the howling noise from the generated sound.
摘要翻译：在抑制啸叫噪声的同时放大声音的装置中，麦克风收集声音并将收集的声音转换成相应的输入信号。放大器放大输入信号，通过扬声器产生声音。在麦克风和放大器之间插入多个均衡器，每个均衡器具有可变的衰减频率，用于对围绕衰减频率的输入信号进行衰减滤波。进行检测，以检测包含在收集的声音中的啸声的多个噪声谱峰。然后，对应于多个检测到的噪声频谱峰值进行调整多个均衡器的各个可变衰减频率，从而从产生的声音中去除啸声。

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