专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20110091968A1 MONOCLONAL ANTIBODY SPECIFIC TO BOTH HUMAN INTERFERON-ALPHA SUBTYPE ALPHA 8 AND ITS MUTANT PROTEINS 失效
标题翻译：人类干扰素ALPHA亚型ALPHA 8及其突变蛋白特异性单克隆抗体
公开(公告)号：US20110091968A1
公开(公告)日：2011-04-21
申请号：US12933768
申请日：2009-03-16
申请人： Shigeharu Fukuda , Chie Ushio , Harumi Ariyasu , Tohru Kayano , Toshio Ariyasu , Tsunetaka Ohta
发明人： Shigeharu Fukuda , Chie Ushio , Harumi Ariyasu , Tohru Kayano , Toshio Ariyasu , Tsunetaka Ohta
IPC分类号： C07K16/24 , G01N33/566 , C07K1/22 , C12N5/16
CPC分类号： C07K16/249 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/76 , G01N33/6866 , G01N2030/8831
摘要： The present invention has the first object to provide a monoclonal antibody specific to interferon α subtype α8 (IFNα8) and its mutant proteins, the second object to provide a hybridoma capable of producing the monoclonal antibody, the third object to provide a method for detecting the IFNα8 and its mutant proteins by the monoclonal antibody, the fourth object to provide a method for purifying the IFNα8 and its mutant proteins by the monoclonal antibody, and the fifth object to provide a therapeutic agent for treating diseases whose onsets or exacerbation are related with IFNα8. The present invention solves the above objects by providing a monoclonal antibody specific to IFNα8 and its mutant proteins, a hybridoma capable of producing the monoclonal antibody, a method for detecting the IFNα8 and its mutant proteins by immunoreaction using the monoclonal antibody, a method for purifying the IFNα8 and its mutant proteins using the monoclonal antibody, and a therapeutic agent for treating diseases whose onsets or exacerbation are related with IFNα8, which contains the monoclonal antibody as an effective ingredient.
摘要翻译：本发明的第一个目的是提供对干扰素α亚型α8（IFNα8）及其突变蛋白特异性的单克隆抗体，第二个目的是提供能产生单克隆抗体的杂交瘤，第三个目的是提供一种检测方法通过单克隆抗体IFNα8及其突变蛋白，第四个目的是提供通过单克隆抗体纯化IFNα8及其突变蛋白的方法，第五个目的是提供一种用于治疗其发作或加重与IFNα8相关的疾病的治疗剂。本发明通过提供对IFNα8及其突变蛋白特异性的单克隆抗体，能够产生单克隆抗体的杂交瘤，通过使用单克隆抗体的免疫反应检测IFNα8及其突变蛋白的方法来解决上述目的，纯化方法使用单克隆抗体的IFNα8及其突变蛋白，以及用于治疗其发作或恶化与IFNα8相关的疾病的治疗剂，其含有单克隆抗体作为有效成分。

2. 发明授权

US08357782B2 Monoclonal antibodies specific for human interferon-alpha subtype alpha 8 失效
标题翻译：对人类干扰素α亚型alpha 8具有特异性的单克隆抗体
公开(公告)号：US08357782B2
公开(公告)日：2013-01-22
申请号：US12933768
申请日：2009-03-16
申请人： Shigeharu Fukuda , Chie Ushio , Harumi Ariyasu , Tohru Kayano , Toshio Ariyasu , Tsunetaka Ohta
发明人： Shigeharu Fukuda , Chie Ushio , Harumi Ariyasu , Tohru Kayano , Toshio Ariyasu , Tsunetaka Ohta
IPC分类号： C07K16/24 , A61K39/395 , C12N5/12
CPC分类号： C07K16/249 , A61K2039/505 , C07K2317/24 , C07K2317/56 , C07K2317/76 , G01N33/6866 , G01N2030/8831
摘要： The present invention has the first object to provide a monoclonal antibody specific to interferon α subtype α8 (IFNα8) and its mutant proteins, the second object to provide a hybridoma capable of producing the monoclonal antibody, the third object to provide a method for detecting the IFNα8 and its mutant proteins by the monoclonal antibody, the fourth object to provide a method for purifying the IFNα8 and its mutant proteins by the monoclonal antibody, and the fifth object to provide a therapeutic agent for treating diseases whose onsets or exacerbation are related with IFNα8. The present invention solves the above objects by providing a monoclonal antibody specific to IFNα8 and its mutant proteins, a hybridoma capable of producing the monoclonal antibody, a method for detecting the IFNα8 and its mutant proteins by immunoreaction using the monoclonal antibody, a method for purifying the IFNα8 and its mutant proteins using the monoclonal antibody, and a therapeutic agent for treating diseases whose onsets or exacerbation are related with IFNα8, which contains the monoclonal antibody as an effective ingredient.
摘要翻译：本发明的第一个目的是提供对干扰素α亚型α8（IFNα8）及其突变蛋白特异性的单克隆抗体，第二个目的是提供能产生单克隆抗体的杂交瘤，第三个目的是提供一种检测方法通过单克隆抗体IFNα8及其突变蛋白，第四个目的是提供通过单克隆抗体纯化IFNα8及其突变蛋白的方法，第五个目的是提供一种用于治疗其发作或加重与IFNα8相关的疾病的治疗剂。本发明通过提供对IFNα8及其突变蛋白特异性的单克隆抗体，能够产生单克隆抗体的杂交瘤，通过使用单克隆抗体的免疫反应检测IFNα8及其突变蛋白的方法来解决上述目的，纯化方法使用单克隆抗体的IFNα8及其突变蛋白，以及用于治疗其发作或恶化与IFNα8相关的疾病的治疗剂，其含有单克隆抗体作为有效成分。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式