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1. 发明授权

US07719427B2 Wireless pH measurement system 有权
标题翻译：无线pH测量系统
公开(公告)号：US07719427B2
公开(公告)日：2010-05-18
申请号：US11465780
申请日：2006-08-18
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Jun-Jie Feng
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Jun-Jie Feng
IPC分类号： G08B23/00
CPC分类号： G01N27/4167 , G01N27/286
摘要： A wireless pH measurement system is disclosed, the wireless pH measurement system includes a portable module and a receiver end. The portable module comprises a signal detecting and processing portion and a wireless transmission portion. The signal detecting and processing portion comprises a sensor unit for detecting a pH signal, amplifying, filtering noise, analog/digital conversion and numerical processing to generate a pH measurement signal. The wireless transmission portion receives the pH measurement signal via a transmission interface and transmits by a Bluetooth module. The receiver end includes a Bluetooth receiver for receiving the pH measurement signal. The receiver end processes the pH measurement signal by programs, displays, analyzes and stores the pH measurement signal and transmits warning signal when an abnormal pH measurement signal is received.
摘要翻译：公开了无线pH测量系统，无线pH测量系统包括便携式模块和接收器端。便携式模块包括信号检测和处理部分和无线传输部分。信号检测和处理部分包括用于检测pH信号，放大，滤波噪声，模拟/数字转换和数值处理以产生pH测量信号的传感器单元。无线传输部分通过传输接口接收pH测量信号，并由蓝牙模块进行传输。接收器端包括用于接收pH测量信号的蓝牙接收器。接收端通过程序，显示，分析和存储pH测量信号处理pH测量信号，并在收到异常pH测量信号时发送警告信号。

2. 发明申请

US20080041721A1 Wireless pH Measurement System 有权
标题翻译：无线pH测量系统
公开(公告)号：US20080041721A1
公开(公告)日：2008-02-21
申请号：US11465780
申请日：2006-08-18
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Jun-Jie Feng
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Jun-Jie Feng
IPC分类号： G01N27/26
CPC分类号： G01N27/4167 , G01N27/286
摘要： A wireless pH measurement system is disclosed, the wireless pH measurement system includes a portable module and a receiver end. The portable module comprises a signal detecting and processing portion and a wireless transmission portion. The signal detecting and processing portion comprises a sensor unit for detecting a pH signal, amplifying, filtering noise, analog/digital conversion and numerical processing to generate a pH measurement signal. The wireless transmission portion receives the pH measurement signal via a transmission interface and transmits by a Bluetooth module. The receiver end includes a Bluetooth receiver for receiving the pH measurement signal. The receiver end processes the pH measurement signal by programs, displays, analyzes and stores the pH measurement signal and transmits warning signal when an abnormal pH measurement signal is received.
摘要翻译：公开了无线pH测量系统，无线pH测量系统包括便携式模块和接收器端。便携式模块包括信号检测和处理部分和无线传输部分。信号检测和处理部分包括用于检测pH信号，放大，滤波噪声，模拟/数字转换和数值处理以产生pH测量信号的传感器单元。无线传输部分通过传输接口接收pH测量信号，并由蓝牙模块进行传输。接收器端包括用于接收pH测量信号的蓝牙接收器。接收端通过程序，显示，分析和存储pH测量信号处理pH测量信号，并在收到异常pH测量信号时发送警告信号。

3. 发明授权

US07736478B2 Ion solution concentration-detecting device 失效
标题翻译：离子溶液浓度检测装置
公开(公告)号：US07736478B2
公开(公告)日：2010-06-15
申请号：US11515727
申请日：2006-09-06
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Chung-We Pan , Chin-Shuen Hung
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Chung-We Pan , Chin-Shuen Hung
IPC分类号： G01N27/333
CPC分类号： G01N27/4035
摘要： An ion solution concentration-detecting device includes a working electrode, a reference electrode, and a link element. The working electrode and the reference electrode are inserted into the link element. The working electrode, inserted into the link element, is replaceable, for the better sensitivity to the different ion solution. The working electrode being a contact-detecting electrode can be replaced by another contact-detecting electrode with different sensing membrane. The reference electrode includes a polymeric membrane with ion material covering silver/silver chloride (Ag/AgCl) electrode to provide a fixed and stable electrical potential. The working electrode may be a contact-detecting electrode having a sensing membrane. The sensing membrane may be a metal oxide or a polymer with ion material for measuring different ion solution effectively.
摘要翻译：离子溶液浓度检测装置包括工作电极，参考电极和连接元件。工作电极和参考电极插入到连接元件中。插入连接元件的工作电极是可更换的，以便更好地对不同离子溶液的敏感性。作为接触检测电极的工作电极可以由具有不同传感膜的另一接触检测电极代替。参考电极包括具有覆盖银/氯化银（Ag / AgCl）电极的离子材料的聚合物膜，以提供固定和稳定的电势。工作电极可以是具有感测膜的接触检测电极。感测膜可以是金属氧化物或具有用于有效测量不同离子溶液的离子材料的聚合物。

4. 发明授权

US07638157B2 Method of fabricating electrode assembly of sensor 失效
标题翻译：制造传感器电极组件的方法
公开(公告)号：US07638157B2
公开(公告)日：2009-12-29
申请号：US11533358
申请日：2006-09-19
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Wen-Yaw Chung , Li-Te Yin , Chung-We Pan
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Wen-Yaw Chung , Li-Te Yin , Chung-We Pan
IPC分类号： G01N1/28
CPC分类号： C12Q1/006 , C12N9/0006 , C12N11/08
摘要： A method of fabricating an electrode assembly of a sensor is described. The sensor has a field effect transistor. The electrode assembly is separated from the field effect transistor by only a conductive line. The sensor is functioned to detect different glucose concentrations. A solid layer of tin oxide is deposited on a substrate board. A β-D-glucose oxidase and polyvinyl alcohol bearing styrylpyridinium groups are placed in 100 μl of sulfuric acid, to form an enzyme mixture. The enzyme mixture is dropped on the solid layer of tin oxide. The enzyme mixture is dried. The enzyme mixture is exposed to a UV ray. The enzyme mixture is dried and stabilized. The enzyme mixture is immersed in a sulfuric buffer.
摘要翻译：描述了制造传感器的电极组件的方法。该传感器具有场效应晶体管。电极组件仅通过导线与场效应晶体管分离。该传感器用于检测不同的葡萄糖浓度。在基板上沉积固体氧化锡层。将β-D-葡萄糖氧化酶和含有苯乙烯基吡啶鎓基团的聚乙烯醇基团置于100毫升硫酸中以形成酶混合物。将酶混合物滴在氧化锡的固体层上。将酶混合物干燥。将酶混合物暴露于紫外线。将酶混合物干燥并稳定。将酶混合物浸入硫酸缓冲液中。

5. 发明申请

US20090119026A1 PORTABLE MULTI-IONS SENSING SYSTEM AND FABRICATION THEREOF 审中-公开
标题翻译：便携式多离子感测系统及其制造方法
公开(公告)号：US20090119026A1
公开(公告)日：2009-05-07
申请号：US11933809
申请日：2007-11-01
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Nien-Hsuan Chou , Gin-Chou Yang
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Nien-Hsuan Chou , Gin-Chou Yang
IPC分类号： G01N31/00 , G01N27/416 , G06F19/00
CPC分类号： G01N27/4148 , G01N27/333
摘要： A portable multi-ions sensing system is provided. The sensing system includes: a sensing unit for sensing a pH value and a plurality of ion concentrations of a solution and outputting a sensing signal, wherein the sensing unit includes: a substrate; an ITO layer on the substrate; a sensing layer on the ITO layer and connected with an extended lead; a packaging layer encapsulating the sensing layer, the ITO layer and a portion of the substrate with a sensing window for exposing a portion of the sensing layer; a multi-ions selective layer on the portion of the sensing layer exposed by the sensing window for sensing the ion concentrations; and a reference electrode for providing a reference potential for the sensing layer; an analog signal processing unit for receiving, filtering, amplifying and adjusting the level of the sensing signal and outputting a front-end signal; a microcontroller unit for receiving and performing analog/digital converting and two-point correcting processes on the front-end signal and outputting a measurement data; and a real-time display unit for receiving and displaying the measurement data.
摘要翻译：提供便携式多离子感测系统。感测系统包括：感测单元，用于感测溶液的pH值和多个离子浓度并输出感测信号，其中感测单元包括：基底; 衬底上的ITO层; ITO层上的传感层，并与延伸引线连接; 封装层，其将所述感测层，所述ITO层和所述衬底的一部分封装以具有用于暴露所述感测层的一部分的感测窗口; 感测层暴露在感测窗口的部分上的多离子选择层，用于感测离子浓度; 以及用于为感测层提供参考电位的参考电极; 模拟信号处理单元，用于接收，滤波，放大和调整感测信号的电平并输出前端信号; 微控制器单元，用于接收并执行前端信号的模拟/数字转换和两点校正处理，并输出测量数据; 以及用于接收和显示测量数据的实时显示单元。

6. 发明申请

US20060021874A1 Fabrication of ceramic interface electrochemical reference electrode 审中-公开
标题翻译：陶瓷界面电化学参考电极的制造
公开(公告)号：US20060021874A1
公开(公告)日：2006-02-02
申请号：US11137551
申请日：2005-05-26
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Chung-We Pan , Zheng-Cheng Chen
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Chung-We Pan , Zheng-Cheng Chen
IPC分类号： G01N27/327 , H01R43/16
CPC分类号： G01N27/401 , Y10T29/49206
摘要： In this present invention it was fabricated to be relates to manufacturing a ceramic interface electrochemical reference electrode for use together with biomedical sensors. Most potentiometric biomedical sensors must have the need to be connected to a reference electrode to offer the readout circuit a stable voltage in the different solutions when measuring for providing that can provide a standard comparing voltage to avoid measuring errors caused by an unstable environment. Usually, However, the presently available commercial reference electrode we used is too big in size and inconvenient to store. For this reason we develop the ceramic interface electrochemical reference electrode which can minimize volume and need not to be preserved in the saturated solution for biosensor. Therefore, the ceramic interface electrochemical reference electrode of the present invention does not need to be stored in solution and can be minimized for use in future sensors. In addition, the present invention also relates to a ceramic interface electrochemical reference electrode.
摘要翻译：在本发明中，其制造涉及制造与生物医学传感器一起使用的陶瓷界面电化学参考电极。大多数电位生物医学传感器必须需要连接到参考电极，以便在测量时提供不同解决方案中的稳定电压，以提供可提供标准比较电压以避免由不稳定环境引起的测量误差。通常，然而，我们使用的目前可用的商业参考电极的尺寸太大并且不方便存储。为此，我们开发了陶瓷界面电化学参比电极，可以使体积最小化，不需要保留在生物传感器的饱和溶液中。因此，本发明的陶瓷界面电化学参考电极不需要存储在溶液中，并且可以最小化以用于将来的传感器。此外，本发明还涉及陶瓷界面电化学参考电极。

7. 发明授权

US07883668B2 Optical blood gas sensor for real time measurement 有权
标题翻译：光学血液气体传感器，用于实时测量
公开(公告)号：US07883668B2
公开(公告)日：2011-02-08
申请号：US11949563
申请日：2007-12-03
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Nien-Hsuan Chou , Chih-Wei Lai
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Nien-Hsuan Chou , Chih-Wei Lai
IPC分类号： G01J1/48
CPC分类号： G01N21/783
摘要： An optical gas concentration sensor and method for measuring blood gas based on the light adsorption sensing technique are disclosed. The optical gas concentration sensor comprises a light source, a photo detector, and a gas filtering membrane for separating the indicator and a liquid. A gas in the liquid diffuses to the indicator through the gas filtering membrane so as to change the color of the indicator due to the chemical reaction occurred between the indicator and the gas. Then, the photo detector receives the light passing though the reacted indicator from the light source. The gas concentration is determined based on pH-sensitive absorbance spectrum of the indicator.
摘要翻译：公开了一种基于光吸收传感技术测量血液气体的光学气体浓度传感器和方法。光学气体浓度传感器包括用于分离指示剂和液体的光源，光电检测器和气体过滤膜。液体中的气体通过气体过滤膜扩散到指示器，以便由于指示剂和气体之间发生化学反应而改变指示器的颜色。然后，光检测器从光源接收通过反应指示器的光。基于指示剂的pH敏感吸收光谱确定气体浓度。

8. 发明申请

US20100140089A1 FLEXIBLE pH SENSORS AND pH SENSING SYSTEMS USING THE SAME 审中-公开
标题翻译：灵活的pH传感器和pH传感系统使用它
公开(公告)号：US20100140089A1
公开(公告)日：2010-06-10
申请号：US12469627
申请日：2009-05-20
申请人： Jung-Chuan Chou , Tai-Ping Sun , Shen-Kan Hsiung , Nien-Hsuan Chou , Sheng-Kai Li
发明人： Jung-Chuan Chou , Tai-Ping Sun , Shen-Kan Hsiung , Nien-Hsuan Chou , Sheng-Kai Li
IPC分类号： G01N27/333
CPC分类号： G01N27/4148
摘要： This invention provides an extended gate ion-sensitive field effect transistor as a pH sensor for measuring the pH value of a solution under test. This invention also provides a pH sensing system comprising a separable and flexible pH sensor for measuring the pH value of a solution under test, wherein the transistor of the pH sensor can be prevented from direct contact with the solution.
摘要翻译：本发明提供了扩展的栅离子敏感场效应晶体管作为用于测量待测溶液的pH值的pH传感器。本发明还提供了一种pH检测系统，其包括用于测量待测溶液的pH值的可分离和柔性的pH传感器，其中可以防止pH传感器的晶体管与溶液直接接触。

9. 发明申请

US20100106425A1 SOLID-STATE UREA BIOSENSOR AND ITS DATA ACQUISITION SYSTEM 审中-公开
标题翻译：固态尿素生物传感器及其数据采集系统
公开(公告)号：US20100106425A1
公开(公告)日：2010-04-29
申请号：US12582687
申请日：2009-10-20
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Chung-We Pan
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Chung-We Pan
IPC分类号： G06F19/00 , G01N33/48
CPC分类号： C12Q1/58
摘要： A data acquisition system for a solid-state urea biosensor uses an amplifier, a low-pass filter and a data acquisition card to acquire and relay data to a computer to be analyzed by a signal analysis program and displayed on a display panel. The biosensor includes a substrate, and three individual sensing areas separated by an insulating layer on the substrate. Each individual sensing area contains a conductive layer on the substrate, and a pH sensitive membrane is deposited thereon. An enzyme layer is deposited on one of the pH sensitive membranes to form a working electrode. The other two sensing areas are a quasi-reference electrode and a contrast electrode, respectively. The signals are transferred to an instrumentation amplifier. The amplified signals are then transferred to a low-pass filter. The filtered signals are analyzed by the program and then displayed on the display panel.
摘要翻译：用于固体尿素生物传感器的数据采集系统使用放大器，低通滤波器和数据采集卡来获得并将数据中继到计算机以由信号分析程序分析并显示在显示面板上。生物传感器包括基板和由基板上的绝缘层分隔开的三个单独的感测区域。每个单独的感测区域在衬底上包含导电层，并且在其上沉积pH敏感膜。酶层沉积在一个pH敏感膜上以形成工作电极。其他两个感测区域分别是准参考电极和对比电极。信号被传送到仪表放大器。然后将放大的信号传送到低通滤波器。滤波后的信号由程序分析，然后显示在显示面板上。

10. 发明授权

US07435610B2 Fabrication of array pH sensitive EGFET and its readout circuit 失效
标题翻译：阵列pH敏感EGFET及其读出电路的制作
公开(公告)号：US07435610B2
公开(公告)日：2008-10-14
申请号：US11342185
申请日：2006-01-26
申请人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Chung-We Pan , Jing-Sheng Chiang
发明人： Shen-Kan Hsiung , Jung-Chuan Chou , Tai-Ping Sun , Chung-We Pan , Jing-Sheng Chiang
IPC分类号： H01L21/00
CPC分类号： G01N27/4148
摘要： A method for fabricating an array pH sensor and a readout circuit device of such array pH sensor are implemented by utilizing an extended ion sensitive field effect transistor to construct the array pH sensor and related readout circuit. The structure of the array sensor having this extended ion sensitive field effect transistor comprises a tin dioxide/metal/silicon dioxide multi-layer structure sensor and a tin dioxide/indium tin oxide/glass multi-layer structure sensor and has excellent properties. Furthermore, the readout circuit and the sensor utilize two signal generators for controlling and reading signals. In particular, the sensor can be effective for increasing the accuracy of measurement and reducing the interference of noise.
摘要翻译：通过利用扩展的离子敏感场效应晶体管构成阵列pH传感器和相关读出电路来实现阵列pH传感器的制造方法和这种阵列pH传感器的读出电路装置。具有该扩展离子敏感场效应晶体管的阵列传感器的结构包括二氧化锡/金属/二氧化硅多层结构传感器和二氧化锡/铟锡氧化物/玻璃多层结构传感器，并且具有优异的性能。此外，读出电路和传感器利用两个信号发生器来控制和读取信号。特别地，传感器可以有效地提高测量的精度并降低噪声的干扰。

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