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    • 5. 发明申请
    • SEPARATOR
    • 分隔器
    • US20130264268A1
    • 2013-10-10
    • US13849045
    • 2013-03-22
    • SEIKO EPSON CORPORATIONSHINSHU UNIVERSITY
    • Satomi YOSHIOKAHiroshi YAGIShigetaka SHIMODAIRA
    • B01D71/74
    • B01D71/74B01D69/02B01D69/10B01D71/40B01D2323/02B01D2323/283B01D2325/36C12M47/04
    • A separator fractionates a dispersion of cells including cells having phagocytic activity corresponding to a size of the cells to obtain a dispersion in which the content of the cells having phagocytic activity is higher than that of the dispersion, and includes a filter, at least part of the filter having a hydrophilic surface as a result of being covered with at least one of a self-assembled monolayer that includes an alkanethiol having a nonionic hydrophilic group that is formed on a gold thin film via a sulfur-gold bond, and a homopolymer or a copolymer of an ester of (meth)acrylic acid and at least some of hydrophilic groups of phospholipids that form a biomembrane. The separator is thus configured so that clogging of the filter is suppressed, and the separation efficiency is improved.
    • 分离器分离细胞分散体,包括具有对应于细胞大小的吞噬活性的细胞,以获得其中具有吞噬活性的细胞的含量高于分散体的分散体的分散体,并且包括过滤器,至少部分 所述过滤器具有由至少一个自组装单层覆盖的亲水表面,所述自组装单层包括通过硫 - 金键形成在金薄膜上的具有非离子亲水基团的链烷硫醇,以及均聚物或 (甲基)丙烯酸酯与形成生物膜的至少一些亲水性磷脂基团的共聚物。 因此,隔膜被构造成能够抑制过滤器的堵塞,提高分离效率。
    • 6. 发明申请
    • GEL FOR SENSOR AND SENSOR
    • 传感器和传感器的凝胶
    • US20160338643A1
    • 2016-11-24
    • US15146172
    • 2016-05-04
    • Seiko Epson Corporation
    • Satomi YOSHIOKAHiroshi YAGI
    • A61B5/00A61B5/145A61B5/053G01N27/04
    • A61B5/6802A61B5/053A61B5/14517A61B2562/14G01N27/04G01N33/5438G01N33/553G01N33/585G01N33/66
    • A sensor includes a gel for a sensor and an electrode. The gel for a sensor includes a stimulus-responsive gel, first particles which are contained in the stimulus-responsive gel and are constituted by a material containing an electrically conductive substance, and second particles which are contained in the stimulus-responsive gel and contribute to structural coloration. It is preferred that when the electrical resistivity of the electrically conductive substance is represented by R1 (Ω·m) and the electrical resistivity of the constituent material of the second particles is represented by R2 (Ω·m), the following relationship is satisfied: 1×1012≦R2/R1≦1×1023. It is preferred that when the refractive index of the constituent material of the first particles is represented by n1 and the refractive index of the constituent material of the second particles is represented by n2, the following relationship is satisfied: −0.8≦n2−n1≦1.5.
    • 传感器包括用于传感器和电极的凝胶。 用于传感器的凝胶包括刺激响应凝胶,包含在刺激响应性凝胶中并由含有导电物质的材料构成的第一颗粒和包含在刺激响应凝胶中的第二颗粒, 结构着色。 优选的是,当导电物质的电阻率由R1(Ω·m)表示,第二粒子的构成材料的电阻率由R2(Ω·m)表示时,满足以下关系: 1×1012≤R2/R1≤1×1023。 优选的是,当第一颗粒的构成材料的折射率由n1表示,并且第二颗粒的​​构成材料的折射率由n2表示时,满足以下关系:-0.8≤n2-n1≤ 1.5。
    • 7. 发明申请
    • GEL SENSOR
    • 凝胶传感器
    • US20160061828A1
    • 2016-03-03
    • US14828698
    • 2015-08-18
    • Seiko Epson Corporation
    • Kei HIRUMAHiroshi YAGI
    • G01N33/543
    • G01N31/22
    • A gel sensor includes a first region constituted by a material containing a stimulus-responsive gel and a second region containing fine particles at a higher content than the first region. It is preferred that the first region does not contain the fine particles. The gel sensor has the first region provided on the upstream side of the second region in the moving direction of a specimen, and when the area of the face of the first region on the upstream side is represented by S1 (mm2) and the area of the face of the second region on the side facing the first region is represented by S2 (mm2), it is preferred to satisfy the following relation: S2≦S1.
    • 凝胶传感器包括由含有刺激响应性凝胶的材料构成的第一区域和含有比第一区域更高含量的微粒子的第二区域。 优选第一区域不含微粒。 凝胶传感器具有在试样的移动方向上设置在第二区域的上游侧的第一区域,并且当上游侧的第一区域的面的面积由S1(mm2)表示时, 面向第一区域的一侧的第二区域的面由S2(mm2)表示,优选满足以下关系:S2≦̸ S1。
    • 8. 发明申请
    • STIMULUS-RESPONSIVE GEL MATERIAL
    • 刺激性凝胶材料
    • US20150226754A1
    • 2015-08-13
    • US14619527
    • 2015-02-11
    • Seiko Epson Corporation
    • Satomi YOSHIOKAHiroshi YAGIJiro KATO
    • G01N33/84G01N31/22
    • G01N33/84G01N2021/7773
    • A stimulus-responsive gel material includes: a polymeric material containing as constituent components, a first monomer having a chemical structure represented by the following formula (1) and a second monomer having higher hydrophobicity than the first monomer; fine particles having an average particle diameter of 10 nm or more and 1000 nm or less; and a solvent, wherein the wavelength of a reflected light from the material changes according to the concentration of salt to come in contact with the material. In the formula (1), R is a substituent containing at least a carbon atom and a hydrogen atom, and when the number of carbon atoms in R is denoted by n and the number of oxygen atoms in R is denoted by m, n-m is an integer of 3 or more.
    • 刺激响应性凝胶材料包括:含有作为构成成分的聚合物材料,具有由下式(1)表示的化学结构的第一单体和比第一单体具有更高疏水性的第二单体; 平均粒径为10nm以上至1000nm以下的微粒; 和溶剂,其中来自材料的反射光的波长根据盐的浓度而变化以与材料接触。 式(1)中,R为至少含有碳原子和氢原子的取代基,R中的碳原子数为n,R中的氧原子数为m,nm为 3以上的整数。