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1. 发明授权

US6130060A Gene encoding for adseverin 失效
标题翻译： adseverin基因编码
公开(公告)号：US6130060A
公开(公告)日：2000-10-10
申请号：US669286
申请日：1996-06-28
申请人： Seiji Nakamura, deceased , Takashi Sakurai , Juni-ichi Nezu
发明人： Seiji Nakamura, deceased , Takashi Sakurai , Juni-ichi Nezu
IPC分类号： G01N33/53 , A61K31/70 , A61K38/00 , A61K38/46 , A61K39/395 , A61K48/00 , A61P3/00 , A61P7/02 , A61P43/00 , C07H21/04 , C07K14/47 , C07K14/575 , C07K16/00 , C12N1/21 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12R1/19 , C12N15/00 , C12N15/63 , C12N15/85
CPC分类号： C07K14/47 , A61K38/00
摘要： A DNA containing a base sequence encoding an amino acid sequence represented by SEQ ID NO:4 or 6 in Sequence Listing, which optionally has partial replacement, deletion or addition, or a base sequence hybridizable therewith; a recombinant vector containing this gene; a transformant constructed by using this vector; a process for producing adseverin by using the above-mentioned gene; a recombinant adseverin protein obtained by this production process; an oligonucleotide hybridizable specifically with a base sequence encoding an amino acid sequence represented by SEQ ID NO:4 or 6; a method for regulating the formation of adseverin in an animal which comprises administering the above-mentioned oligonucleotide to the animal; and an antibody capable of recognizing adseverin protein.
摘要翻译： PCT No.PCT / JP94 / 02227 Sec。 371日期1997年8月25日第 102（e）日期1997年8月25日PCT 1994年12月27日PCT PCT。 WO95 / 18221 PCT出版物日期1995年7月6日含有编码序列表中SEQ ID NO：4或6所示的氨基酸序列的碱基序列的DNA，其任选具有部分替换，缺失或添加，或与其可杂交的碱基序列; 含有该基因的重组载体; 通过使用该载体构建的转化体; 通过使用上述基因产生adseverin的方法; 通过该生产方法获得的重组adseverin蛋白; 与编码SEQ ID NO：4或6所示的氨基酸序列的碱基序列特异性杂交的寡核苷酸; 一种用于调节动物中adseverin形成的方法，其包括向动物施用上述寡核苷酸; 和能够识别adseverin蛋白的抗体。

2. 发明授权

US06271353B1 Antibodies specific for human adseverin 有权
标题翻译：针对人类adseverin的抗体
公开(公告)号：US06271353B1
公开(公告)日：2001-08-07
申请号：US09642146
申请日：2000-08-21
申请人： Seiji Nakamura , Takashi Sakurai , Juni-ichi Nezu
发明人： Seiji Nakamura , Takashi Sakurai , Juni-ichi Nezu
IPC分类号： C07K1600
CPC分类号： C07K14/47 , A61K38/00
摘要： A DNA containing a base sequence encoding an amino acid sequence represented by SEQ ID NO:4 or 6 in Sequence Listing, which optionally has partial replacement, deletion or addition, or a base sequence hybridizable therewith; a recombinant vector containing this gene; a transformant constructed by using this vector; a process for producing adseverin by using the above-mentioned gene; a recombinant adseverin protein obtained by this production process; an oligonucleotide hybridizable specifically with a base sequence encoding an amino acid sequence represented by SEQ ID NO:4 or 6; a method for regulating the formation of adseverin in an animal which comprises administering the above-mentioned oligonucleotide to the animal; and an antibody capable of recognizing adseverin protein.
摘要翻译：含有编码序列表中SEQ ID NO：4或6所示的氨基酸序列的碱基序列的DNA，其任选具有部分置换，缺失或添加，或与其可杂交的碱基序列; 含有该基因的重组载体; 通过使用该载体构建的转化体; 通过使用上述基因产生adseverin的方法; 通过该生产方法获得的重组adseverin蛋白; 与编码SEQ ID NO：4或6所示的氨基酸序列的碱基序列特异性杂交的寡核苷酸; 一种用于调节动物中adseverin形成的方法，其包括向动物施用上述寡核苷酸; 和能够识别adseverin蛋白的抗体。

3. 发明授权

US06184352B2 Adseverin protein 有权
标题翻译： Adseverin蛋白
公开(公告)号：US06184352B2
公开(公告)日：2001-02-06
申请号：US09469253
申请日：1999-12-22
申请人： Seiji Nakamura , Takashi Sakurai , Juni-ichi Nezu
发明人： Seiji Nakamura , Takashi Sakurai , Juni-ichi Nezu
IPC分类号： C07K1400
CPC分类号： C07K14/47 , A61K38/00
摘要： A DNA containing a base sequence encoding an amino acid sequence represented by SEQ ID NO: 4 or 6 in Sequence Listing, which optionally has partial replacement, deletion or addition, or a base sequence hybridizable therewith; a recombinant vector containing this gene; a transformant constructed by using this vector; a process for producing adseverin by using the above-mentioned gene; a recombinant adseverin protein obtained by this production process; an oligonucleotide hybridizable specifically with a base sequence encoding an amino acid sequence represented by SEQ ID NO: 4 or 6; a method for regulating the formation of adseverin in an animal which comprises administering the above-mentioned oligonucleotide to the animal; and an antibody capable of recognizing adseverin protein.
摘要翻译：含有编码序列表中SEQ ID NO：4或6所示的氨基酸序列的碱基序列的DNA，其任选具有部分置换，缺失或添加，或与其可杂交的碱基序列; 含有该基因的重组载体; 通过使用该载体构建的转化体; 通过使用上述基因产生adseverin的方法; 通过该生产方法获得的重组adseverin蛋白; 与编码SEQ ID NO：4或6所示的氨基酸序列的碱基序列特异性杂交的寡核苷酸; 一种用于调节动物中adseverin形成的方法，其包括向动物施用上述寡核苷酸; 和能够识别adseverin蛋白的抗体。

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