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2. 发明申请

US20150196475A1 Cosmetic Composition Containing Acetylated Oligoglucuronans 审中-公开
标题翻译：含有乙酰化寡糖苷酸的化妆品组合物
公开(公告)号：US20150196475A1
公开(公告)日：2015-07-16
申请号：US14665821
申请日：2015-03-23
申请人： Sederma, S.A.S.
发明人： Arnaud Fournial , Claire-Marie Grizaud , Caroline Le Moigne , Philippe Mondon
IPC分类号： A61K8/73 , A61Q19/02 , A61K9/00 , A61Q17/04 , A61Q19/08 , A61Q19/00
CPC分类号： A61K8/73 , A61K8/0216 , A61K9/0014 , A61Q17/04 , A61Q19/007 , A61Q19/02 , A61Q19/08 , C08B37/006
摘要： The present invention relates to the field of cosmetic and dermopharmaceutical compositions. It concerns oligomer compounds of D-glucuronic acid or D-glucuronate with a β (1-4) sequence (or oligoglucuronans) containing a degree of acetylation specifically between 8.7±0.5 and 9.2±0.5% by weight of O—CO—CH3 group compared to the weight of glucuronic acid and with a degree of polymerisation (DP) of 18-19±2. The oligomer compounds according to the present invention are intended to stimulate the elasticity of the dermis and epidermis although they also act to increase dermo-epidermal cohesion in order to combat skin ageing, lines, wrinkles, visible and/or tactile skin discontinuities, loss of firmness, elasticity and tone and to combat skin tissue deformability. The invention also concerns a cosmetic composition containing at least one compound as recited according to the present invention.
摘要翻译：本发明涉及化妆品和皮肤药物组合物领域。它涉及D-葡萄糖醛酸或D-葡萄糖醛酸的低聚物化合物，（1-4）序列（或寡聚葡萄糖醛酸糖苷），其特征在于与葡萄糖醛酸的重量和聚合度（DP）相比，其特征在于乙酰化度在8.7±0.5至9.2±0.5％（重量）的O-CO-CH 3基团之间，为18-19±2。根据本发明的低聚物化合物旨在刺激真皮和表皮的弹性，尽管它们还用于增加皮肤表皮内聚力以抵抗皮肤老化，线，皱纹，可见和/或触觉皮肤不连续性，丧失坚实，弹性和色调，以及对抗皮肤组织的变形能力。本发明还涉及包含至少一种根据本发明的化合物的化妆品组合物。

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