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    • 8. 发明申请
    • IMAGING SYSTEM AND ASSOCIATED METHOD FOR DETECTION OF PROTEIN CONTAMINATION
    • 用于检测蛋白质污染的成像系统和相关方法
    • US20130224869A1
    • 2013-08-29
    • US13817911
    • 2011-08-12
    • David PerrettNanda Kishore NayuniPaul EllwoodRichard MaskellAlasdair Hayden WrightSarah ThompsonLaura Sullivan
    • David PerrettNanda Kishore NayuniPaul EllwoodRichard MaskellAlasdair Hayden WrightSarah ThompsonLaura Sullivan
    • G01N33/68
    • G01N33/6839G01N21/6428G01N21/6456G01N21/94
    • An imaging system (10) and associated method for detection of protein contamination on a surgical instrument (100) that has been treated with a fluorescing stain, wherein fluorophors in the stain are capable of emitting light of an emitted type when both excited by light of an excitation type and in contact with a protein are provided. The system comprises a light tight chamber (14) for receiving the instrument (100). Inside the chamber (14) are both visible light sources (20) and excitation light sources (22) for respectively illuminating the chamber with visible and excitation type light. A digital camera (30) is able to capture a first image of the instrument (100) as illuminated by the visible light, and a second image, of patterns of fluorescence produced by the fluorophors in the stain corresponding to protein contamination. The first and second images are combined to produce a composite image of the instrument (100) highlighting the areas of protein contamination. Associated software can be used to analyse the images so as to determine a level of protein contamination.
    • 一种成像系统(10)和用于检测已经用荧光染色剂处理的外科器械(100)上的蛋白污染的相关方法,其中染色体中的荧光体能够发射发射的光,当两者都被光 提供了与蛋白质接触的激发型。 该系统包括用于接收仪器(100)的不透光室(14)。 在室(14)内部是可见光源(20)和激发光源(22),用于分别用可见光和激发型光照射室。 数字照相机(30)能够捕获由可见光照射的仪器(100)的第一图像,以及第二图像,其中荧光体在染色体中产生的与蛋白质污染相对应的荧光图案。 组合第一和第二图像以产生突出蛋白质污染区域的仪器(100)的合成图像。 相关软件可用于分析图像,以确定蛋白质污染水平。