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    • 3. 发明申请
    • Polypropylene cable jacket compositons with enhanced melt strength and physical properties
    • 聚丙烯电缆护套组合物具有增强的熔体强度和物理性能
    • US20050241820A1
    • 2005-11-03
    • US10527221
    • 2003-09-10
    • Scott WassermanGeoffrey Brown
    • Scott WassermanGeoffrey Brown
    • H01B7/02E21B33/12G02B6/02G02B6/14G02B6/44H01B3/00H01B3/18H01B3/44H01B7/17
    • G02B6/4429G02B6/14G02B6/4486H01B3/441
    • The present invention is a cable comprising one or more telecommunication or power transmission media or a core of two or more such media, each medium or core surrounded by at least one jacketing or sheathing layer comprising a polypropylene homopolymer or copolymer and having a relaxation spectrum (RSI) and melt flow (MF) such RSI*MF{circumflex over ( )}a is greater than about 12 when a is about 0.5. Significantly, the jacketing or sheathing layer exhibits advantaged extrusion fabrication charateristics, resulting from the propylene polymer having enhanced rheology properties (as demonstrated by its high relaxation spectrum index (RSI)). Additionally, the propylene-based polymer composition of the present invention exhibits relaxtively high melt strength compared to compounds of conventional propylene polymers or ethylene polymers. In fiber optic cable jacketing applications, the present invention advantageously balances low post extrusion shrinkage with high modulus/deformation resistance.
    • 本发明是一种电缆,其包括一个或多个电信或电力传输介质或两个或更多个这样的介质的芯,每个介质或芯由包含聚丙烯均聚物或共聚物的至少一个护套或护层包围,并具有松弛光谱 RSI)和熔体流动(MF),如果约为0.5,则RSI * MF {circumflex over()} a大于约12。 重要的是,护套或护套层具有优异的挤出制造特征,由丙烯聚合物具有增强的流变性能(如通过其高弛豫频谱指数(RSI)所证明的))。 此外,与常规丙烯聚合物或乙烯聚合物的化合物相比,本发明的基于丙烯的聚合物组合物显示出松弛的高熔体强度。 在光缆护套应用中,本发明有利地将低后挤压收缩与高模量/变形阻力平衡。
    • 5. 发明申请
    • METHOD FOR TREATING OSTEOPOROSIS
    • 治疗OSTEOPOSOSIS的方法
    • US20140127192A1
    • 2014-05-08
    • US14112667
    • 2012-04-18
    • Javier San MartinScott Wasserman
    • Javier San MartinScott Wasserman
    • A61K39/395
    • A61K39/3955A61K2039/505A61K2039/545C07K16/22C07K2317/76
    • The invention is directed to a method for increasing bone mineral density (BMD) in a postmenopausal woman. The method comprises administering to a postmenopausal woman having a lumbar vertebrae T-score of less than or equal to −2 an anti-sclerostin antibody in an amount and for a time effective to increase lumbar vertebrae BMD at least about 9% from pretreatment baseline at twelve months following initial anti-sclerostin antibody administration. The invention also is directed to a method for treating osteoporosis. The method comprising administering to a postmenopausal woman with osteoporosis an anti-sclerostin antibody in an amount of about 70 mg to about 210 mg at once a month, optionally for about three to about 18 months. Alternatively, the method comprises administering an anti-sclerostin antibody in an amount of about 140 mg to about 210 mg every three months, optionally about six to about 18 months.
    • 本发明涉及一种增加绝经后妇女骨密度(BMD)的方法。 所述方法包括对具有小于或等于-2的腰椎T评分的绝经后女性施用抗硬化蛋白抗体,其量和时间有效地将腰椎BMD从预处理基线增加至少约9% 最初的抗硬皮素抗体给药后12个月。 本发明还涉及一种治疗骨质疏松症的方法。 该方法包括对绝经后的女性骨质疏松症施用,每月一次约70mg至约210mg的抗硬化性抗体,任选约3至约18个月。 或者,该方法包括每三个月施用约140mg至约210mg的抗硬化蛋白抗体,任选约六至约十八个月。