专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050095587A1 Molecules for disease detection and treatment 审中-公开
标题翻译：用于疾病检测和治疗的分子
公开(公告)号：US20050095587A1
公开(公告)日：2005-05-05
申请号：US10204921
申请日：2001-02-21
申请人： Scott Panzer , Peter Shapiro , Steven Banville , Purvi Shah , Michael Chalup , Simon Chang , Alice Chen , Steven D'sa , Stefan Amshey , Christopher Dahl , Tam Dam , Susan Daniels , Gerard Dufour , Vincent Flores , Willy Fong , Lila Greenawalt , Jennifer Jackson , Anissa Jones , Tommy Liu , Ann Roseberry Lincoln , Bruce Rosen , Frank Russo , Theresa Stockdreher , Abel Daffo , Rachel Wright , Pierre Yap , Jimmy Yu , Diana Bradley , Shawn Bratcher , Wensheng Chen , Howard Cohen , David Hodgson , Stephen Lincoln , Stuart Jackson
发明人： Scott Panzer , Peter Shapiro , Steven Banville , Purvi Shah , Michael Chalup , Simon Chang , Alice Chen , Steven D'sa , Stefan Amshey , Christopher Dahl , Tam Dam , Susan Daniels , Gerard Dufour , Vincent Flores , Willy Fong , Lila Greenawalt , Jennifer Jackson , Anissa Jones , Tommy Liu , Ann Roseberry Lincoln , Bruce Rosen , Frank Russo , Theresa Stockdreher , Abel Daffo , Rachel Wright , Pierre Yap , Jimmy Yu , Diana Bradley , Shawn Bratcher , Wensheng Chen , Howard Cohen , David Hodgson , Stephen Lincoln , Stuart Jackson
IPC分类号： A61K38/00 , C07K14/47 , C12N15/12 , C12Q1/68 , C07H21/04
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00
摘要： The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce anitbodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.
摘要翻译：本发明提供了纯化的疾病检测和治疗分子多核苷酸（mddt）。还包括由mddt编码的多肽（MDDT）。本发明还提供在诊断测定中使用mddt或其互补序列，寡核苷酸或其片段。本发明进一步提供含有mddt用于表达MDDT的载体和宿主细胞。本发明另外提供分离和纯化的MDDT在诊断测定中诱导化合物和筛选化合物文库以及使用抗MDDT抗体的用途。还提供了含有mddt和使用方法的微阵列。

2. 发明申请

US20050013888A1 Apparatus for making a reinforced fibrous absorbent member 失效
标题翻译：用于制造增强纤维吸收件的装置
公开(公告)号：US20050013888A1
公开(公告)日：2005-01-20
申请号：US10917115
申请日：2004-08-12
申请人： Michael Venturino , Susan Daniels , David Heyn , James Kaun , Derek Murphy
发明人： Michael Venturino , Susan Daniels , David Heyn , James Kaun , Derek Murphy
IPC分类号： A61F13/15 , B27N1/00
CPC分类号： A61F13/4702 , A61F13/15626 , A61F13/15634 , A61F13/534 , A61F13/539 , A61F2013/53463
摘要： Apparatus for making a reinforced fibrous absorbent member includes a forming chamber adapted to receive a fluent fibrous material and a forming surface moveable within the forming chamber and adapted to collect fibrous material to form the absorbent member. A source of reinforcing web is disposed exteriorly of the forming chamber. A delivery tube has an inlet end open to the forming chamber exterior, a discharge end open to the forming chamber interior, and a central passage extending between the inlet end and the discharge end. At least a portion of the delivery tube adjacent the discharge end extends within the forming chamber interior. The delivery tube is arranged for receiving the reinforcing web from the source of reinforcing web into the central passage of the tube at the inlet end and for guiding the web to the discharge end for conveyance within the forming chamber toward the forming surface.
摘要翻译：用于制造增强的纤维吸收件的装置包括适于容纳流体纤维材料的成形室和可在成形室内移动的适于聚集纤维材料以形成吸收件的成形表面。增强纤维网的源部设置在成形室的外部。输送管具有通向成形室外部的入口端，通向成形室内部的排出端，以及在入口端和排出端之间延伸的中心通道。邻近排出端的输送管的至少一部分在成形室内部延伸。输送管被布置成用于将加强幅材从加强幅材源接收到入口端的管的中心通道中，并且用于将幅材引导到排出端，以在成形室内朝向成形表面传送。

3. 发明申请

US20110184712A1 PREDICTIVE MODELS AND METHODS FOR DIAGNOSING AND ASSESSING CORONARY ARTERY DISEASE 审中-公开
标题翻译：用于诊断和评估冠状动脉疾病的预测模型和方法
公开(公告)号：US20110184712A1
公开(公告)日：2011-07-28
申请号：US12682579
申请日：2008-10-10
申请人： Steve Rosenberg , Susan Daniels , Michael R. Elashoff , James A. Wingrove , Whittemore G. Tingley , Amy J. Sehnert , Nicholas F. Paoni
发明人： Steve Rosenberg , Susan Daniels , Michael R. Elashoff , James A. Wingrove , Whittemore G. Tingley , Amy J. Sehnert , Nicholas F. Paoni
IPC分类号： G06G7/60
CPC分类号： C12Q1/6883 , C12Q2600/112 , C12Q2600/158
摘要： Biomarkers useful for diagnosing and assessing the extent of coronary artery disease (CAD) are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. In a preferred embodiment, the biomarkers are organized into clustered groups. The expression level of the biomarkers within a group are highly correlated to each other in normal and disease states. Expression values of genes chosen from each of two, three, four or five of the clustered gene groups, A, B, C, D, E may be used. Alternatively, expression values of genes chosen from the groups are combined into a metagene. Preferred biomarkers include S100A12, S100A8, S100A9, BCL2A1, and F5 (group A); XK, P62, and FECH (group B); TUBB2 (group C); IFNG, PDGFB, VSIG4, and TNF (group D); CSF3R, TLR5, CD46, and NCF1 (group E); S100A12, S100A9, BCL2A1, TXN and CSTA (group I); OLIG1, OLIG2, ADORA3, CLC, and SLC29A1 (group II); and CBS and ARG1 (group IV).
摘要翻译：提供了有助于诊断和评估冠状动脉疾病（CAD）程度的生物标志物，以及用于测量其表达的试剂盒。本发明还提供了基于生物标志物的预测模型，以及用于评分和可选地分类样品的模型的计算机系统和软件实施方案。在优选的实施方案中，生物标志物被组织成聚集的组。一组中生物标志物的表达水平在正常和疾病状态下彼此高度相关。可以使用从两个，三个，四个或五个聚簇基因组A，B，C，D，E中的每一个中选择的基因的表达值。或者，选自组中的基因的表达值被组合成元源。优选的生物标志物包括S100A12，S100A8，S100A9，BCL2A1和F5（组A）; XK，P62和FECH（B组）; TUBB2（C组）; IFNG，PDGFB，VSIG4和TNF（D组）; CSF3R，TLR5，CD46和NCF1（组E）; S100A12，S100A9，BCL2A1，TXN和CSTA（组I）; OLIG1，OLIG2，ADORA3，CLC和SLC29A1（组II）; 和CBS和ARG1（组IV）。

4. 发明申请

US20070248708A1 Apparatus for Making a Reinforced Fibrous Absorbent Member 失效
标题翻译：用于制造增强纤维吸收件的装置
公开(公告)号：US20070248708A1
公开(公告)日：2007-10-25
申请号：US11677857
申请日：2007-02-22
申请人： Michael Venturino , Susan Daniels , David Heyn , James Kaun , Derek Murphy
发明人： Michael Venturino , Susan Daniels , David Heyn , James Kaun , Derek Murphy
IPC分类号： B28B5/10
CPC分类号： A61F13/4702 , A61F13/15626 , A61F13/15634 , A61F13/534 , A61F13/539 , A61F2013/53463
摘要： Apparatus for making a reinforced absorbent member includes a forming chamber adapted to contain a fluent fibrous material. A forming surface is moveable within the forming chamber along an arcuate path generally from an entrance of the forming chamber to an exit thereof. The forming surface is adapted to collect fibrous material thereon to form the absorbent member. A source of reinforcing web is disposed generally exterior of the forming chamber. The forming chamber has an opening through which the reinforcing web is received into the forming chamber for subsequent conveyance within the forming chamber toward the forming surface. The opening is disposed downstream of the forming chamber entrance generally in the direction of movement of the forming surface along the path.
摘要翻译：用于制造增强的吸收构件的装置包括适于容纳流体纤维材料的成形室。成形表面可以在成形室内沿着通常从成形室的入口到其出口的弓形路径移动。成形表面适于在其上收集纤维材料以形成吸收件。加强网的来源通常设置在成形室的外部。成形室具有开口，加强网通过该开口容纳到成形室中，用于随后在成形室内朝向成形表面传送。开口通常沿成形表面沿着路径移动的方向设置在成形室入口的下游。

5. 发明申请

US20070045906A1 Method and apparatus to shape a composite structure without contact 失效
标题翻译：在没有接触的状态下成型复合结构的方法和装置
公开(公告)号：US20070045906A1
公开(公告)日：2007-03-01
申请号：US11216423
申请日：2005-08-30
申请人： Susan Daniels , Sara Schewe , Randall Foss , David Hunter , Michael Schmidt
发明人： Susan Daniels , Sara Schewe , Randall Foss , David Hunter , Michael Schmidt
IPC分类号： D04H5/00
CPC分类号： D04H1/56 , D04H1/407 , D04H1/425 , D04H1/732 , D04H3/05 , D04H5/08
摘要： A method and apparatus including means for delivery of at least one high speed composite stream of polymer fibers and secondary material. The method and apparatus also includes a movable collection device which intersects in the composite stream of polymer fibers and secondary material and at least one non-contact deflector to redirect at least a portion of the composite stream.
摘要翻译：一种方法和装置，包括用于输送聚合物纤维和次级材料的至少一种高速复合物流的装置。该方法和装置还包括可移动收集装置，其在聚合物纤维和次级材料的复合流中相交，以及至少一个非接触偏转器，以重定向至少一部分复合流。

6. 发明申请

US20070045905A1 Method and apparatus to mechanically shape a composite structure 失效
标题翻译：机械地成型复合结构的方法和装置
公开(公告)号：US20070045905A1
公开(公告)日：2007-03-01
申请号：US11215864
申请日：2005-08-30
申请人： Michael Venturino , Seth Newlin , Paul Olmstead , Susan Daniels , Sara Schewe
发明人： Michael Venturino , Seth Newlin , Paul Olmstead , Susan Daniels , Sara Schewe
IPC分类号： D04H5/00
CPC分类号： A61F13/15658 , D04H1/425 , D04H1/4382
摘要： An apparatus for forming a shaped fibrous nonwoven structure including a delivery system adapted to provide a high speed composite stream comprising thermoplastic polymer fibers and a secondary material. The apparatus also includes a movable collection device having a collection surface which intersects the composite stream, and at least one deflector to mechanically redirect at least a portion of the composite stream. Further the deflector moves in synchronization with the movable collection device, such that the composite stream is collected on the collection surface forming a fibrous nonwoven structure having at least one non-linear edge.
摘要翻译：一种用于形成成形纤维非织造结构的装置，包括适于提供包含热塑性聚合物纤维和次级材料的高速复合料流的输送系统。该装置还包括具有与复合流相交的收集表面的可移动收集装置，以及至少一个偏转器，用于机械地重定向至少一部分复合流。此外，偏转器与可移动收集装置同步地移动，使得复合流被收集在收集表面上，形成具有至少一个非线性边缘的纤维非织造结构。

7. 发明申请

US20060071360A1 Method and apparatus for scarfing fibrous substrates 有权
标题翻译：剥离纤维基材的方法和设备
公开(公告)号：US20060071360A1
公开(公告)日：2006-04-06
申请号：US10954821
申请日：2004-09-29
申请人： Dixon Kuchenbecker , Bruce Benson , Susan Daniels , Michael Venturino , Joseph Kugler
发明人： Dixon Kuchenbecker , Bruce Benson , Susan Daniels , Michael Venturino , Joseph Kugler
IPC分类号： D01G25/00 , D21B1/04
CPC分类号： A61F13/15617 , D04H1/732 , Y10T403/553
摘要： An apparatus for scarfing a fibrous web includes a rotatable scarfing roll with vacuum ports and an air moving source in fluid communication with the vacuum ports. The rotatable scarfing roll has a core member which includes a plurality of scarfing elements connected thereto and vacuum ports located therein. A method for scarfing a fibrous web includes providing a rotatable scarfing roll with vacuum ports and reducing scarfing wind by applying vacuum to the vacuum ports. A method for producing absorbent articles includes providing a fibrous web, contacting the fibrous web with a rotatable scarfing roll with vacuum ports to remove a portion of the fibrous web, applying vacuum to the vacuum ports to reduce scarfing wind, and producing an absorbent article with the fibrous web.
摘要翻译：用于对纤维幅材进行剥皮的设备包括具有真空端口的可旋转切割辊和与真空端口流体连通的空气移动源。可旋转的剥皮辊具有芯部件，该芯部件包括与其连接的多个切割元件和位于其中的真空端口。用于对纤维幅材进行剥皮的方法包括：通过向真空端口施加真空来提供具有真空端口的可旋转的剥皮辊并减少刮花风。一种制造吸收性物品的方法包括提供纤维网，使纤维网与可旋转的具有真空端口的切割辊接触以除去纤维网的一部分，向真空端口施加真空以减少刮花风，并制备具有纤维网。

8. 发明申请

US20050261657A1 Absorbent core with elongate liquid holding formation 有权
标题翻译：具有细长液体保持结构的吸收芯
公开(公告)号：US20050261657A1
公开(公告)日：2005-11-24
申请号：US11193697
申请日：2005-07-29
申请人： Michael Venturino , Susan Daniels , Steven Milanowski
发明人： Michael Venturino , Susan Daniels , Steven Milanowski
IPC分类号： A61F5/44 , A61F13/15 , D04H1/72
CPC分类号： A61F13/532 , A61F13/15626 , Y10T442/60
摘要： An absorbent core comprises an elongate liquid holding formation with a peripheral edge. The liquid holding formation has a surface formed with at least one channel extending longitudinally in the core for distributing liquid lengthwise along the core. The channel has longitudinally opposite ends spaced longitudinally inward from the peripheral edge of the liquid holding formation to inhibit the flow of liquid in the channels past the peripheral edge of the liquid holding formation.
摘要翻译：吸收芯包括具有周边边缘的细长液体保持结构。液体保持结构具有形成有在芯中纵向延伸的至少一个通道的表面，用于沿着芯纵向地分配液体。通道具有从液体保持结构的周缘纵向向内间隔的纵向相对端，以阻止通道中的液体流过液体保持结构的周边边缘。

9. 发明申请

US20050246006A1 Electrical nerve stimulation device 审中-公开
标题翻译：电神经刺激装置
公开(公告)号：US20050246006A1
公开(公告)日：2005-11-03
申请号：US10954653
申请日：2004-10-01
申请人： Susan Daniels
发明人： Susan Daniels
IPC分类号： A61N1/05 , A61N1/34 , A61N1/36 , A61N1/372 , A61N1/18
CPC分类号： A61N1/0551 , A61N1/025 , A61N1/36071 , A61N1/37211
摘要： The present invention relates to an electrical nerve stimulation device, along with associated methods of use and manufacture. A particular, but not exclusive, application of the invention is subcutaneous electrical nerve stimulation (SENS) for relief of neuropathic pain.
摘要翻译：本发明涉及电神经刺激装置，以及相关的使用和制造方法。本发明的一个特别但不排他的应用是用于缓解神经性疼痛的皮下电神经刺激（SENS）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式