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1. 发明授权

US06367740B1 Air foil having a hybrid leading edge construction 失效
标题翻译：具有混合前缘结构的气翼
公开(公告)号：US06367740B1
公开(公告)日：2002-04-09
申请号：US09572382
申请日：2000-05-16
申请人： Scott E. Johnson , Vann Heng , Guillermo Mas
发明人： Scott E. Johnson , Vann Heng , Guillermo Mas
IPC分类号： B64C338
CPC分类号： B64C3/36 , B64C3/28
摘要： A leading edge component for reducing drag and improving heat sink properties of an air foil. The leading edge component includes a composite tile component with a predetermined aerodynamic shape and a metallic lip portion with high thermal conductivity. The metallic lip portion is secured to a forwardmost edge portion of the composite tile component to thereby form a leading edge of the air foil. The leading edge component is better able to withstand the structural stresses and extremely high temperatures that result while travelling at hypersonic speeds, without a significant increase in weight to the air foil with which the leading edge component is used.
摘要翻译：用于减少阻力并改善气翼的散热性能的前沿部件。前缘部件包括具有预定空气动力学形状的复合瓦片部件和具有高导热性的金属唇部分。金属唇部固定在复合瓷砖部件的最前缘部分上，从而形成空气箔的前缘。前缘部件能够更好地承受在超音速行驶时产生的结构应力和极高的温度，而不会使用前缘部件使用的气翼的重量显着增加。

2. 外观设计

USD716731S1 Transducer mounting block 有权
标题翻译：传感器安装块
公开(公告)号：USD716731S1
公开(公告)日：2014-11-04
申请号：US29433292
申请日：2012-09-27
申请人： Scott E. Johnson
设计人： Scott E. Johnson

3. 发明申请

US20090136548A1 MULTIPLE ANTIGENIC PEPTIDES IMMUNOGENIC AGAINST STREPTOCOCCUS PNEUMONIA 有权
标题翻译：多发性抗原肽免疫球蛋白抗菌肽
公开(公告)号：US20090136548A1
公开(公告)日：2009-05-28
申请号：US12360382
申请日：2009-01-27
申请人： Edwin W. Ades , Scott E. Johnson , Danny L. Jue , Jacquelyn S. Sampson , George M. Carlone
发明人： Edwin W. Ades , Scott E. Johnson , Danny L. Jue , Jacquelyn S. Sampson , George M. Carlone
IPC分类号： A61K39/09 , C07K7/06 , C07K7/08 , A61P37/04 , C07K14/315
CPC分类号： C07K7/08 , A61K38/00 , A61K39/00 , C07K14/3156 , Y10S530/806 , Y10S530/825
摘要： The invention provides a nucleic acid encoding the 37-kDa pneumococcal surface adhesion A protein (PsaA) from Streptococcus pneumoniae. The invention also provides purified polypeptides encoded by the nucleic acid encoding the 37-kDa protein from and the nucleic acids comprising unique fragment of at least 10 nucleotides of the 37-kDa protein. Additionally, multiple antigenic peptides that provide protection against S. pneumoniae challenge are provided. These multiple antigen peptides comprise the peptides that immunospecifically bind to the monoclonal antibodies. Also provided are vaccines comprising such immunogenic peptides, and methods of conferring protective immunity against Streptococcus pneumoniae infection by administering therapeutic composition comprising the immunogenic peptides of the invention. Also provided are methods of detecting the presence of Streptococcus pneumoniae in a sample using antibodies or antigens and methods of preventing and treating Streptococcus pneumoniae infection in a subject.
摘要翻译：本发明提供编码来自肺炎链球菌的37-kDa肺炎球菌表面粘附A蛋白（PsaA）的核酸。本发明还提供由编码37-kDa蛋白质的核酸编码的纯化多肽和包含37-kDa蛋白质至少10个核苷酸的独特片段的核酸。另外，提供了提供针对肺炎链球菌攻击的保护的多种抗原肽。这些多重抗原肽包含免疫特异性结合单克隆抗体的肽。还提供了包含这种免疫原性肽的疫苗，以及通过施用包含本发明的免疫原性肽的治疗组合物来赋予对肺炎链球菌感染的保护性免疫的方法。还提供了使用抗体或抗原检测样品中肺炎链球菌存在的方法以及在受试者中预防和治疗肺炎链球菌感染的方法。

4. 发明授权

US06903184B1 Multiple antigenic peptides immunogenic against Streptococcus pneumonia 有权
标题翻译：针对肺炎链球菌免疫原性的多种抗原肽
公开(公告)号：US06903184B1
公开(公告)日：2005-06-07
申请号：US09613092
申请日：2000-07-10
申请人： Edwin W. Ades , Scott E. Johnson , Danny L. Jue , Jacquelyn S. Sampson , George M. Carlone
发明人： Edwin W. Ades , Scott E. Johnson , Danny L. Jue , Jacquelyn S. Sampson , George M. Carlone
IPC分类号： A61K38/00 , A61K39/00 , C07K7/08 , C07K14/315 , C07K2/00 , A61K39/02 , A61K39/09 , C07K1/00 , C07K5/00
CPC分类号： C07K7/08 , A61K38/00 , A61K39/00 , C07K14/3156 , Y10S530/806 , Y10S530/825
摘要： The invention provides a nucleic acid encoding the 37-kDa pneumococcal surface adhesion A protein (PsaA) from Streptococcus pneumoniae. The invention also provides purified polypeptides encoded by the nucleic acid encoding the 37-kDa protein from and the nucleic acids comprising unique fragment of at least 10 nucleotides of the 37-kDa protein. Additionally, multiple antigenic peptides that provide protection against S. pneumoniae challenge are provided. These multiple antigen peptides comprise the peptides that immunospecifically bind to the monoclonal antibodies. Also provided are vaccines comprising such immunogenic peptides, and methods of conferring protective immunity against Streptococcus pneumoniae infection by administering therapeutic composition comprising the immunogenic peptides of the invention. Also provided are methods of detecting the presence of Streptococcus pneumoniae in a sample using antibodies or antigens and methods of preventing and treating Streptococcus pneumoniae infection in a subject.
摘要翻译：本发明提供编码来自肺炎链球菌的37-kDa肺炎球菌表面粘附A蛋白（PsaA）的核酸。本发明还提供由编码37-kDa蛋白质的核酸编码的纯化多肽和包含37-kDa蛋白质至少10个核苷酸的独特片段的核酸。另外，提供了提供针对肺炎链球菌攻击的保护的多种抗原肽。这些多重抗原肽包含免疫特异性结合单克隆抗体的肽。还提供了包含这种免疫原性肽的疫苗，以及通过施用包含本发明的免疫原性肽的治疗组合物来赋予对肺炎链球菌感染的保护性免疫的方法。还提供了使用抗体或抗原检测样品中肺炎链球菌存在的方法以及在受试者中预防和治疗肺炎链球菌感染的方法。

5. 发明授权

US08947979B2 Transducer mounting blocks and method of use thereof 有权
标题翻译：传感器安装座及其使用方法
公开(公告)号：US08947979B2
公开(公告)日：2015-02-03
申请号：US13673948
申请日：2012-11-09
申请人： Scott E. Johnson
发明人： Scott E. Johnson
IPC分类号： G10K11/00 , F16M13/00 , B63B17/00
CPC分类号： G10K11/006 , B63B17/00
摘要： A mounting block for fastening equipment such as a sonar transducer onto the hull or transom of a boat which consists of a flat body portion formed into a predetermined size and shape, the body further having a front face and a back face, the back face further having one or more channel grooves for retaining an adhesive, the channel grooves further having internal surfaces to provide mechanical grip to the hardened adhesive thereby preventing mechanical separation between sonar transducer or other equipment and the mounting block.
摘要翻译：一种用于将诸如声纳换能器的紧固装置固定到船体的船体或横梁上的安装块，其由形成为预定尺寸和形状的平坦主体部分组成，所述主体还具有前表面和后表面，所述后表面进一步具有用于保持粘合剂的一个或多个通道槽，所述通道槽还具有内表面以对硬化的粘合剂提供机械抓握，从而防止声纳换能器或其他设备与安装块之间的机械分离。

6. 发明授权

US07501132B2 Multiple antigenic peptides immunogenic against Streptococcus pneumonia 有权
标题翻译：针对肺炎链球菌免疫原性的多种抗原肽
公开(公告)号：US07501132B2
公开(公告)日：2009-03-10
申请号：US11145814
申请日：2005-06-06
申请人： Edwin W. Ades , Scott E. Johnson , Danny L. Jue , Jacquelyn S. Sampson , George M. Carlone
发明人： Edwin W. Ades , Scott E. Johnson , Danny L. Jue , Jacquelyn S. Sampson , George M. Carlone
IPC分类号： A61K39/09 , A61K39/02 , A61K39/38 , A61K39/385 , A61K38/00 , A01N37/18
CPC分类号： C07K7/08 , A61K38/00 , A61K39/00 , C07K14/3156 , Y10S530/806 , Y10S530/825
摘要： The invention provides a nucleic acid encoding the 37-kDa pneumococcal surface adhesion A protein (PsaA) from Streptococcus pneumoniae. Also provided are isolated nucleic acids comprising a unique fragment of at least 10 nucleotides of the 37-kDa protein. The invention also provides purified polypeptides encoded by the nucleic acid encoding the 37-kDa protein from and the nucleic acids comprising unique fragment of at least 10 nucleotides of the 37-kDa protein. The invention further provides monoclonal antibodies which selectively bind PsaA. In addition, peptides are provided that immunospecifically bind to the monoclonal antibodies of the invention, and that are immunogenic against Streptococcus pneumoniae infection. Additionally, multiple antigenic peptides that provide protection against S. pneumoniae challenge are provided. These multiple antigen peptides comprise the peptides that immunospecifically bind to the monoclonal antibodies. Also provided are vaccines comprising such immunogenic peptides, and methods of conferring protective immunity against Streptococcus pneumoniae infection by administering therapeutic composition comprising the immunogenic peptides of the invention. Also provided are methods of detecting the presence of Streptococcus pneumoniae in a sample using antibodies or antigens and methods of preventing and treating Streptococcus pneumoniae infection in a subject. In addition, a method of identifying the sequence of a peptide potentially capable of eliciting protective immunity against a pathogenic microorganism is provided.
摘要翻译：本发明提供编码来自肺炎链球菌的37-kDa肺炎球菌表面粘附A蛋白（PsaA）的核酸。还提供了分离的核酸，其包含37-kDa蛋白质的至少10个核苷酸的独特片段。本发明还提供由编码37-kDa蛋白质的核酸编码的纯化多肽和包含37-kDa蛋白质至少10个核苷酸的独特片段的核酸。本发明还提供选择性结合PsaA的单克隆抗体。此外，提供了免疫特异性结合本发明的单克隆抗体并且对肺炎链球菌感染具有免疫原性的肽。另外，提供了提供针对肺炎链球菌攻击的保护的多种抗原肽。这些多重抗原肽包含免疫特异性结合单克隆抗体的肽。还提供了包含这种免疫原性肽的疫苗，以及通过施用包含本发明的免疫原性肽的治疗组合物来赋予对肺炎链球菌感染的保护性免疫的方法。还提供了使用抗体或抗原检测样品中肺炎链球菌存在的方法以及在受试者中预防和治疗肺炎链球菌感染的方法。此外，提供了鉴定潜在地能够引发对病原微生物的保护性免疫的肽的序列的方法。

7. 发明授权

US06483337B1 Method for achieving synchronous non-destructive latchup characterization 失效
标题翻译：实现同步非破坏性闭锁特性的方法
公开(公告)号：US06483337B1
公开(公告)日：2002-11-19
申请号：US09625393
申请日：2000-07-26
申请人： Richard C. Blish , Scott E. Johnson
发明人： Richard C. Blish , Scott E. Johnson
IPC分类号： G01R3126
CPC分类号： G01R31/2853 , G01R31/275
摘要： A semiconductor structure is tested for latchup characteristics by imposing increasing levels of current thereon, and measuring increase in structure current in response thereto. When an imposition in current results in a corresponding increase in semiconductor structure current which is not substantially linearly proportional to the amount of current imposed thereon, onset of latchup is indicated. Other semiconductor structures are tested, and measurements are compared to gain knowledge of the structures tested.
摘要翻译：通过在其上施加增加的电流电流并测量结构电流的增加来测试半导体结构的闭锁特性。当电流的施加导致半导体结构电流的相应增加，其基本上与施加在其上的电流量基本上成线性比例时，表示闭锁的开始。测试其他半导体结构，并比较测量结果以获得所测试结构的知识。

8. 发明申请

US20200269945A1 MOTORCYCLE COVER 审中-公开
公开(公告)号：US20200269945A1
公开(公告)日：2020-08-27
申请号：US16542063
申请日：2019-08-15
申请人： Scott E. Johnson , John A. Romeo , Robert Edgar
发明人： Scott E. Johnson , John A. Romeo , Robert Edgar
IPC分类号： B62J19/00
摘要： Various examples of a motorcycle cover are provided. The cover can include a main body comprising a one or more layered material. The one or more layered material can include a flame resistant material, a heat reflective material, and a heat resistant material. The cover can also include one or more regions connected to and/or within the main body. The one or more regions can be configured to hold a stabilizing material to increase stability of the cover. The cover can be configured to protect the motorcycle within an inner side of the cover from a fire exterior to an outer side of the cover.

9. 外观设计

USD422585S Housing for a two-way portable communication device 失效
公开(公告)号：USD422585S
公开(公告)日：2000-04-11
申请号：US109817
申请日：1999-08-24
申请人： Phoebe Ng , Scott E. Johnson
设计人： Phoebe Ng , Scott E. Johnson

10. 发明授权

US08642048B2 Multiple antigenic peptides immunogenic against Streptococcus pneumonia 有权
标题翻译：针对肺炎链球菌免疫原性的多种抗原肽
公开(公告)号：US08642048B2
公开(公告)日：2014-02-04
申请号：US12360382
申请日：2009-01-27
申请人： Edwin W. Ades , Scott E. Johnson , Danny L. Jue , Jacquelyn S. Sampson , George M. Carlone
发明人： Edwin W. Ades , Scott E. Johnson , Danny L. Jue , Jacquelyn S. Sampson , George M. Carlone
IPC分类号： A61K39/00 , A61K39/02 , A61K39/09 , A61K38/00 , C07K2/00
CPC分类号： C07K7/08 , A61K38/00 , A61K39/00 , C07K14/3156 , Y10S530/806 , Y10S530/825
摘要： The invention provides a nucleic acid encoding the 37-kDa pneumococcal surface adhesion A protein (PsaA) from Streptococcus pneumoniae. The invention also provides purified polypeptides encoded by the nucleic acid encoding the 37-kDa protein from and the nucleic acids comprising unique fragment of at least 10 nucleotides of the 37-kDa protein. Additionally, multiple antigenic peptides that provide protection against S. pneumoniae challenge are provided. These multiple antigen peptides comprise the peptides that immunospecifically bind to the monoclonal antibodies. Also provided are vaccines comprising such immunogenic peptides, and methods of conferring protective immunity against Streptococcus pneumoniae infection by administering therapeutic composition comprising the immunogenic peptides of the invention. Also provided are methods of detecting the presence of Streptococcus pneumoniae in a sample using antibodies or antigens and methods of preventing and treating Streptococcus pneumoniae infection in a subject.
摘要翻译：本发明提供编码来自肺炎链球菌的37-kDa肺炎球菌表面粘附A蛋白（PsaA）的核酸。本发明还提供由编码37-kDa蛋白质的核酸编码的纯化多肽和包含37-kDa蛋白质至少10个核苷酸的独特片段的核酸。另外，提供了提供针对肺炎链球菌攻击的保护的多种抗原肽。这些多重抗原肽包含免疫特异性结合单克隆抗体的肽。还提供了包含这种免疫原性肽的疫苗，以及通过施用包含本发明的免疫原性肽的治疗组合物来赋予对肺炎链球菌感染的保护性免疫的方法。还提供了使用抗体或抗原检测样品中肺炎链球菌存在的方法以及在受试者中预防和治疗肺炎链球菌感染的方法。

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