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1. 发明授权

US5373016A Protection of isothiazolinone biocides from free radicals 失效
标题翻译：保护来自自由基的异噻唑啉酮杀生物剂
公开(公告)号：US5373016A
公开(公告)日：1994-12-13
申请号：US68459
申请日：1993-05-28
申请人： Scott A. Brown , Terry Young
发明人： Scott A. Brown , Terry Young
IPC分类号： A01N25/22 , A01N43/80 , C07D275/02
CPC分类号： A01N43/80
摘要： Biocidal isothiazolinone or isothiazolothione compounds are stabilized with an effective amount of a free-radical scavenger compound. Exemplary of the biocidal isothiazolones are 1,2-benzisothiazolin-3-one, 2-methyl-4-5-trimethylene-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one. Effective free-radical scavengers include 3,3-thiodipropionic acid.
摘要翻译：杀生物异噻唑啉酮或异噻唑硫酮化合物用有效量的自由基清除剂化合物稳定。杀生物异噻唑啉酮的实例是1,2-苯并异噻唑啉-3-酮，2-甲基-4,5-三亚甲基-4-异噻唑啉-3-酮，5-氯-2-甲基-4-异噻唑啉-3-酮和 2-甲基-4-异噻唑啉-3-酮。有效的自由基清除剂包括3,3-硫代二丙酸。

2. 发明授权

US6074657A Administration of an injectable antibiotic in the ear of an animal 失效
标题翻译：在动物耳内施用可注射的抗生素
公开(公告)号：US6074657A
公开(公告)日：2000-06-13
申请号：US822195
申请日：1997-03-20
申请人： Scott A. Brown
发明人： Scott A. Brown
IPC分类号： A61K9/107 , A61K9/08 , A61K31/545 , A61K45/00 , A61P31/00 , A61F2/02
CPC分类号： A61K9/08 , A61K31/545
摘要： The present invention provides for a method of injecting an antibiotic in the ear of an animal, such as cattle, swine, sheep and goats. These injectable antibiotics include the following: injectable suspensions of sparingly water-soluble antimicrobial agents, such as procaine penicillin, benzathine penicillin, ceftiofur crystalline free acid ceftiofur hydrochloride, ampicillin trihydrate and amoxicillin trihydrate; sustained-release non-aqueous solutions of sparingly water-soluble antimicrobial agents, such as oxytetracycline, erythromycin, tylosin, tilmicosin and florfenicol; and injectable solutions of zwitterionic antimicrobial agents, such as enrofloxacin, danofloxacin and premafloxacin. Specifically, the present invention provides for a method of injecting a relatively large volume (1 to 15 mL) of a sterile oil suspension of an antibiotic, such as ceftiofur crystalline free acid, in the posterior of the ear of cattle and swine.
摘要翻译：本发明提供了在动物如牛，猪，绵羊和山羊的耳朵中注射抗生素的方法。这些可注射抗生素包括以下：微量水溶性抗微生物剂的注射悬浮液，如普鲁卡因青霉素，苄星青霉素，头孢噻呋结晶游离酸盐酸头孢曲肟，氨苄青霉素三水合物和阿莫西林三水合物; 缓释性非水溶液的微水溶性抗微生物剂，如土霉素，红霉素，泰乐菌素，替米考星和氟苯尼考; 和两性离子抗微生物剂如恩氟沙星，丹诺沙星和前列沙星的可注射溶液。具体而言，本发明提供了在牛和猪耳朵的后部将相当大体积（1至15mL）的抗生素无头油悬浮液（例如头孢噻呋结晶游离酸）注射的方法。

3. 发明授权

US07829100B2 Pharmaceutical composition having modified carrier 有权
标题翻译：具有改良载体的药物组合物
公开(公告)号：US07829100B2
公开(公告)日：2010-11-09
申请号：US10704989
申请日：2003-11-10
申请人： Dirk L. Teagarden , Nancy J. Britten , Scott A. Brown , James F. Caputo , Leslie C. Eaton , Ondrej Hendl , Syed F. Huda , Harry M. King , Susan M. Machkovech , Randal Lee Schapaugh , Stanley M. Speaker , Jean M. Steele , Ching-Chiang Su , Terry R. Urban , Niki A. Waldron , Monica L. Whitmire
发明人： Dirk L. Teagarden , Nancy J. Britten , Scott A. Brown , James F. Caputo , Leslie C. Eaton , Ondrej Hendl , Syed F. Huda , Harry M. King , Susan M. Machkovech , Randal Lee Schapaugh , Stanley M. Speaker , Jean M. Steele , Ching-Chiang Su , Terry R. Urban , Niki A. Waldron , Monica L. Whitmire
IPC分类号： A61K31/545 , A61K39/12
CPC分类号： A61K9/0019 , A61K31/415 , A61K31/43 , A61K31/545 , A61K31/65 , A61K45/06 , A61K47/06 , A61K47/14 , A61K47/44 , A61K2300/00
摘要： A composition comprising: (a) one to three bioactive agents; and (b) a modified liquid vehicle; wherein immediately after manufacture of the composition, said composition can be administered to a host such that the one to three bioactive agents is released to the host on a sustained basis is provided.
摘要翻译：一种组合物，其包含：（a）一至三种生物活性剂; 和（b）改性液体载体; 其中在组合物制造之后立即提供所述组合物给宿主，使得一至三个生物活性剂以持续的方式释放到宿主。

4. 发明授权

US06521673B1 Composition and method for preparing polyurethanes and polyurethane foams 有权
公开(公告)号：US06521673B1
公开(公告)日：2003-02-18
申请号：US09685309
申请日：2000-10-10
申请人： Scott A. Brown
发明人： Scott A. Brown
IPC分类号： C08J900
CPC分类号： E01C23/10 , C08G18/4804 , C08G2101/00 , C08J2205/052
摘要： Polyurethane forming compositions having a water insoluble, non-hydrocarbon diluent provide polyurethanes with improved properties. Polyurethane forming reaction mixtures having a water insoluble diluent provide compositions that permit the formation of polyurethanes in the presence of excess water. Polyurethane forming reaction mixtures having a water insoluble diluent provide compositions that permit the formation of water-blown, low-density polyurethanes in the presence of excess water. Polyurethane forming reaction mixtures having a water insoluble diluent provide compositions that permit the formation of water-blown, low-density polyurethanes. Polyurethane forming compositions having a water insoluble, non-hydrocarbon diluent provide polyurethane foams with improved dimensional stability properties. Polyurethane forming compositions having a water insoluble, non-hydrocarbon diluent provide polyurethane elastomers in the presence of water.

5. 发明授权

US08968759B2 Method of administering an injectable antibiotic to an animal 有权
公开(公告)号：US08968759B2
公开(公告)日：2015-03-03
申请号：US12912942
申请日：2010-10-27
申请人： Scott A. Brown
发明人： Scott A. Brown
IPC分类号： A61K31/546 , A61K31/00 , A61K31/496 , A61D7/00 , A61K31/65 , A61K31/7048
CPC分类号： A61K9/0046 , A61D7/00 , A61K9/0019 , A61K31/496 , A61K31/546 , A61K31/65 , A61K31/7048
摘要： A method of administering an antibiotic to an animal in need thereof, including the step of injecting the antibiotic subcutaneously at the junction of a pinna with the cranium of the animal, is disclosed.

6. 发明申请

US20110098266A1 METHOD OF ADMINISTERING AN INJECTABLE ANTIBIOTIC TO AN ANIMAL 有权
标题翻译：对动物施用抗生素的方法
公开(公告)号：US20110098266A1
公开(公告)日：2011-04-28
申请号：US12912942
申请日：2010-10-27
申请人： Scott A. Brown
发明人： Scott A. Brown
IPC分类号： A61K31/546 , A61P31/00
CPC分类号： A61K9/0046 , A61D7/00 , A61K9/0019 , A61K31/496 , A61K31/546 , A61K31/65 , A61K31/7048
摘要： A method of administering an antibiotic to an animal in need thereof, including the step of injecting the antibiotic subcutaneously at the junction of a pinna with the cranium of the animal, is disclosed.
摘要翻译：公开了向有需要的动物施用抗生素的方法，包括将皮下注射到针the接头处的动物的颅骨的步骤。

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