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1. 发明申请

US20110300118A1 AGENTS FOR PROMOTING IGA PRODUCTION 失效
标题翻译：促进伊朗生产的代理人
公开(公告)号：US20110300118A1
公开(公告)日：2011-12-08
申请号：US13208597
申请日：2011-08-12
申请人： Satoshi HACHIMURA , Hiroki Kanzato , Shigeru Fujiwara
发明人： Satoshi HACHIMURA , Hiroki Kanzato , Shigeru Fujiwara
IPC分类号： A61K35/74 , A61P37/02
CPC分类号： C12R1/225 , A61K35/747 , C12N1/20
摘要： The present invention provides Lactobacillus bacteria which enhance the functional of Peyer's patch and promote IgA production and which have a characteristics of localizing on human intestine as well as an agent for promoting IgA production. The present invention is directed to an agent for promoting IgA production containing Lactobacillus amylovorus cells, especially Lactobacillus amylovorus CP1750 (FERM BP-10532) as an active ingredient,
摘要翻译：本发明提供了增强派尔氏贴剂功能并促进IgA生产并且具有定位在人肠上的特征以及用于促进IgA生产的药剂的乳杆菌属细菌。本发明涉及用于促进含有乳酸乳杆菌（Lactobacillus amylovorus）细胞，特别是乳酸乳杆菌CP1750（FERM BP-10532）作为活性成分的IgA产生剂，

2. 发明申请

US20100247575A1 AGENTS FOR PROMOTING IGA PRODUCTION 审中-公开
标题翻译：促进伊朗生产的代理人
公开(公告)号：US20100247575A1
公开(公告)日：2010-09-30
申请号：US12487978
申请日：2009-06-19
申请人： Satoshi HACHIMURA , Hiroki Kanzato , Shigeru Fujiwara
发明人： Satoshi HACHIMURA , Hiroki Kanzato , Shigeru Fujiwara
IPC分类号： A61K39/02 , C12N1/20 , A61P37/04 , A61P31/00
CPC分类号： C12R1/225 , A61K35/747 , C12N1/20
摘要： The present invention provides Lactobacillus bacteria which enhance the functional of Peyer's patch and promote IgA production and which have a characteristics of localizing on human intestine as well as an agent for promoting IgA production. The present invention is directed to an agent for promoting IgA production containing Lactobacillus amylovorus cells, especially Lactobacillus amylovorus CP1750 (FERM BP-10532) as an active ingredient,
摘要翻译：本发明提供了增强派尔氏贴剂功能并促进IgA生产并且具有定位在人肠上的特征以及用于促进IgA生产的药剂的乳杆菌属细菌。本发明涉及用于促进含有乳酸乳杆菌（Lactobacillus amylovorus）细胞，特别是乳酸乳杆菌CP1750（FERM BP-10532）作为活性成分的IgA产生剂，

3. 发明申请

US20080166787A1 T Cell Apoptosis Inducer 审中-公开
标题翻译： T细胞凋亡诱导剂
公开(公告)号：US20080166787A1
公开(公告)日：2008-07-10
申请号：US11883377
申请日：2006-03-06
申请人： Shigeru Fujiwara , Hiroki Kanzato , Satoshi Hachimura
发明人： Shigeru Fujiwara , Hiroki Kanzato , Satoshi Hachimura
IPC分类号： C12N1/20
CPC分类号： A23L33/135 , A23Y2220/05 , A23Y2300/55 , A61K35/745 , A61K35/747 , C12N1/20 , C12R1/225 , C12R1/23
摘要： An inducer of T cell apoptosis and a health food for inducing T cell apoptosis comprising as an active ingredient of a lactic acid bacterium belonging to the genus Lactobacillus or the genus Bifidobacterium are disclosed. Particularly preferred lactic acid bacteria belonging to the genus Lactobacillus or the genus Bifidobacterium are Lactobacillus acidophilus L-92 (FERM BP-4981), Lactobacillus amylovorus CP1750 (FERM BP-10532), Bifidobacterium catenulatum CP2829 (FERM BP-10533) and Bifidobacterium longum CP760 (FERM BP-10531). The inducer of T cell apoptosis of the invention is useful in the prevention and cure of a disease such as an organ-specific autoimmune disease or type I allergy.
摘要翻译：公开了一种T细胞凋亡诱导剂和用于诱导T细胞凋亡的保健食品，其包含属于乳杆菌属或双歧杆菌属的乳酸菌的活性成分。属于乳杆菌属或双歧杆菌属的特别优选的乳酸菌是嗜酸乳杆菌L-92（FERM BP-4981），淀粉乳杆菌CP1750（FERM BP-10532），连锁双歧杆菌CP2829（FERM BP-10533）和长双歧杆菌CP760 （FERM BP-10531）。本发明的T细胞凋亡诱导剂可用于预防和治疗诸如器官特异性自身免疫性疾病或I型变态反应的疾病。

4. 发明授权

US09339055B2 T cell apoptosis inducer and method therefore 有权
标题翻译：因此T细胞凋亡诱导剂和方法
公开(公告)号：US09339055B2
公开(公告)日：2016-05-17
申请号：US13167483
申请日：2011-06-23
申请人： Shigeru Fujiwara , Hiroki Kanzato , Satoshi Hachimura
发明人： Shigeru Fujiwara , Hiroki Kanzato , Satoshi Hachimura
IPC分类号： C12N1/20 , A23L1/30 , A61K35/745 , A61K35/747 , C12R1/225 , C12R1/23
CPC分类号： A23L1/3014 , A23L33/135 , A23Y2220/05 , A23Y2300/55 , A61K35/745 , A61K35/747 , C12N1/20 , C12R1/225 , C12R1/23
摘要： An inducer of T cell apoptosis and a health food for inducing T cell apoptosis comprising as an active ingredient of a lactic acid bacterium belonging to the genus Lactobacillus or the genus Bifidobacterium are disclosed. Particularly preferred lactic acid bacteria belonging to the genus Lactobacillus or the genus Bifidobacterium are Lactobacillus acidophilus L-92 (FERM BP-4981), Lactobacillus amylovorus CP1750 (FERM BP-10532), Bifidobacterium catenulatum CP2829 (FERM BP-10533) and Bifidobacterium longum CP760 (FERM BP-10531). The inducer of T cell apoptosis of the invention is useful in the prevention and cure of a disease such as an organ-specific autoimmune disease or type I allergy.
摘要翻译：公开了一种T细胞凋亡诱导剂和用于诱导T细胞凋亡的保健食品，其包含属于乳杆菌属或双歧杆菌属的乳酸菌的活性成分。属于乳杆菌属或双歧杆菌属的特别优选的乳酸菌是嗜酸乳杆菌L-92（FERM BP-4981），淀粉乳杆菌CP1750（FERM BP-10532），连锁双歧杆菌CP2829（FERM BP-10533）和长双歧杆菌CP760 （FERM BP-10531）。本发明的T细胞凋亡诱导剂可用于预防和治疗诸如器官特异性自身免疫性疾病或I型变态反应的疾病。

5. 发明授权

US08226937B2 Agents for promoting IgA production 失效
标题翻译：促进IgA生产的药剂
公开(公告)号：US08226937B2
公开(公告)日：2012-07-24
申请号：US13208597
申请日：2011-08-12
申请人： Satoshi Hachimura , Hiroki Kanzato , Shigeru Fujiwara
发明人： Satoshi Hachimura , Hiroki Kanzato , Shigeru Fujiwara
IPC分类号： A61K39/02
CPC分类号： C12R1/225 , A61K35/747 , C12N1/20
摘要： The present invention provides Lactobacillus bacteria which enhance the functional of Peyer's patch and promote IgA production and which have a characteristics of localizing on human intestine as well as an agent for promoting IgA production. The present invention is directed to an agent for promoting IgA production containing Lactobacillus amylovorus cells, especially Lactobacillus amylovorus CP1750 (FERM BP-10532) as an active ingredient.
摘要翻译：本发明提供了增强派尔氏贴剂功能并促进IgA生产并且具有定位在人肠上的特征以及用于促进IgA生产的药剂的乳杆菌属细菌。本发明涉及用于促进含有乳酸干酪乳杆菌细胞，特别是乳酸乳杆菌CP1750（FERM BP-10532）作为活性成分的IgA生产的药剂。

6. 发明申请

US20110250189A1 T CELL APOPTOSIS INDUCER 有权
标题翻译：细胞凋亡诱导因子
公开(公告)号：US20110250189A1
公开(公告)日：2011-10-13
申请号：US13167483
申请日：2011-06-23
申请人： Shigeru Fujiwara , Hiroki Kanzato , Satoshi Hachimura
发明人： Shigeru Fujiwara , Hiroki Kanzato , Satoshi Hachimura
IPC分类号： A61K35/74 , C12N1/20 , A61P43/00
CPC分类号： A23L1/3014 , A23L33/135 , A23Y2220/05 , A23Y2300/55 , A61K35/745 , A61K35/747 , C12N1/20 , C12R1/225 , C12R1/23
摘要： An inducer of T cell apoptosis and a health food for inducing T cell apoptosis comprising as an active ingredient of a lactic acid bacterium belonging to the genus Lactobacillus or the genus Bifidobacterium are disclosed. Particularly preferred lactic acid bacteria belonging to the genus Lactobacillus or the genus Bifidobacterium are Lactobacillus acidophilus L-92 (FERM BP-4981), Lactobacillus amylovorus CP1750 (FERM BP-10532), Bifidobacterium catenulatum CP2829 (FERM BP-10533) and Bifidobacterium longum CP760 (FERM BP-10531). The inducer of T cell apoptosis of the invention is useful in the prevention and cure of a disease such as an organ-specific autoimmune disease or type I allergy.
摘要翻译：公开了一种T细胞凋亡诱导剂和用于诱导T细胞凋亡的保健食品，其包含属于乳杆菌属或双歧杆菌属的乳酸菌的活性成分。属于乳杆菌属或双歧杆菌属的特别优选的乳酸菌是嗜酸乳杆菌L-92（FERM BP-4981），淀粉乳杆菌CP1750（FERM BP-10532），连锁双歧杆菌CP2829（FERM BP-10533）和长双歧杆菌CP760 （FERM BP-10531）。本发明的T细胞凋亡诱导剂可用于预防和治疗诸如器官特异性自身免疫性疾病或I型变态反应的疾病。

7. 发明授权

US09468657B2 Lactic acid bacterium agent for improving lipid metabolism 有权
标题翻译：用于改善脂质代谢的乳酸菌剂
公开(公告)号：US09468657B2
公开(公告)日：2016-10-18
申请号：US13702742
申请日：2011-06-08
申请人： Futoshi Nakamura , Yu Ishida , Shigeru Fujiwara
发明人： Futoshi Nakamura , Yu Ishida , Shigeru Fujiwara
IPC分类号： G01N33/554 , A61K35/74 , A23D7/005 , A23D9/007 , A23L1/30 , A61K35/747 , A23L2/52
CPC分类号： A61K35/74 , A23D7/0053 , A23D7/0056 , A23D9/007 , A23K10/16 , A23L2/52 , A23L33/135 , A23Y2220/00 , A61K35/747
摘要： This invention provides an effective means or method for improving lipid metabolism, and a means or method for treatment or prevention of diseases or disorders associated with the lipid metabolism disorder. Specifically, this invention relates to an agent for improving the lipid metabolism comprising, as active ingredients, broken cells of a lactic acid bacterium, and to a method for enhancing an effect of a lactic acid bacterium for improving the lipid metabolism comprising a step of breaking the lactic acid bacterium.
摘要翻译：本发明提供了改善脂质代谢的有效手段或方法，以及用于治疗或预防与脂质代谢紊乱相关的疾病或病症的方法或方法。具体地说，本发明涉及一种改善脂质代谢的药剂，其特征在于，其含有作为活性成分的乳酸菌的破碎细胞，以及提高乳酸菌用于改善脂质代谢的效果的方法，其特征在于，包括：乳酸菌。

8. 发明申请

US20120141175A1 IMAGE FORMING APPARATUS AND IMAGE FORMING AND ERASING METHOD 有权
标题翻译：图像形成装置和图像形成和擦除方法
公开(公告)号：US20120141175A1
公开(公告)日：2012-06-07
申请号：US13291338
申请日：2011-11-08
申请人： Shigeru Fujiwara , Satoshi Kinouchi , Ryota Saeki , Shoko Shimmura , Kazutoshi Takahashi , Toshihiro Sone , Takafumi Amano
发明人： Shigeru Fujiwara , Satoshi Kinouchi , Ryota Saeki , Shoko Shimmura , Kazutoshi Takahashi , Toshihiro Sone , Takafumi Amano
IPC分类号： G03G15/20
CPC分类号： G03G15/6573 , G03G15/6585 , G03G15/6591
摘要： An image forming apparatus according to an embodiment includes: an image erasing section including a first member which has an elastic layer and heats a recording medium having a thermally decolorizable toner image on the toner image side and a second member which erases the toner image by allowing the recording medium in cooperation with the first member; an image forming section which transfers a thermally decolorizable toner image onto the recording medium on which the toner image is erased to form an unfixed toner image; and an image fixing section including a third member which does not have an elastic layer and heats the recording medium on the unfixed toner image side and a fourth member which fixes the unfixed toner image by allowing the recording medium in cooperation with the third member.
摘要翻译：根据实施例的图像形成装置包括：图像擦除部分，包括具有弹性层的第一部件，并且在调色剂图像侧加热具有热可脱色调色剂图像的记录介质，以及通过允许调色剂图像来擦除调色剂图像的第二部件记录介质与第一个成员协作; 将热可脱色调色剂图像转印到其上清除调色剂图像的记录介质上以形成未定影的调色剂图像的图像形成部分; 以及图像定影部，其包括不具有弹性层的第三构件，并且对未定影的调色剂像侧加热记录介质;以及第四构件，其通过允许记录介质与第三构件协作来固定未定影的调色剂图像。

9. 发明申请

US20120069077A1 MEDIUM HOLDING APPARATUS, INKJET IMAGE FORMING APPARATUS AND INKJET IMAGE FORMING METHOD 审中-公开
标题翻译：中压控制装置，喷墨图像形成装置和喷墨图像形成方法
公开(公告)号：US20120069077A1
公开(公告)日：2012-03-22
申请号：US13232499
申请日：2011-09-14
申请人： Yoshiaki Kaneko , Hirofumi Kondo , Shigeru Fujiwara
发明人： Yoshiaki Kaneko , Hirofumi Kondo , Shigeru Fujiwara
IPC分类号： B41J29/38
CPC分类号： B41J13/223
摘要： According to one embodiment, a medium holding apparatus includes an endless device configured to rotate at a predetermined circumferential speed, a charging member arranged to be opposed to the surface of the endless device and configured to apply a voltage to a medium and attract the medium to the endless device using electrostatic force, a charge removing member arranged to be opposed to the surface of the endless device and configured to discharge charges in the medium using an alternating voltage, and a controller configured to offset a reference voltage of the alternating voltage to a polarity opposite to the polarity of the voltage applied during the attraction.
摘要翻译：根据一个实施例，一种介质保持装置包括构造成以预定的圆周速度旋转的环形装置，充电构件布置成与环形装置的表面相对并且被配置为向介质施加电压并将介质吸引到使用静电力的环形装置，电荷去除部件，被布置成与环形装置的表面相对并且被配置为使用交流电压对介质中的电荷进行放电;以及控制器，被配置为将交流电压的参考电压偏移到极性与吸引期间施加的电压的极性相反。

10. 发明申请

US20100266320A1 IMAGE FORMING APPARATUS WITH CLEANING DEVICE AND CLEANING METHOD 有权
标题翻译：具有清洁装置和清洁方法的图像形成装置
公开(公告)号：US20100266320A1
公开(公告)日：2010-10-21
申请号：US12822506
申请日：2010-06-24
申请人： Shigeru Fujiwara
发明人： Shigeru Fujiwara
IPC分类号： G03G21/00
CPC分类号： G03G21/0029
摘要： In an image forming apparatus including a cleaning device having a cleaning blade arranged so as to make contact with and separate from a cleaned surface, an occurrence of excessive cutting when the cleaning blade makes contact with the cleaned surface is prevented. The image forming apparatus includes the cleaning blade for making contact with and separating from the cleaned surface and scraping off toner adhered onto the cleaned surface and a regulation unit for regulating a movement of the cleaning blade in the direction of contact with the cleaned surface up to a position where a pressing force to the cleaned surface by the cleaning blade does not exceed a predetermined pressing force.
摘要翻译：在包括具有布置成与清洁表面接触并与其分离的清洁刮板的清洁装置的图像形成装置中，防止了当清洁刮板与清洁表面接触时出现过度切割。图像形成装置包括用于与清洁表面接触并与其分离并清除附着在清洁表面上的调色剂的清洁刮板和用于调节清洁刮板沿与清洁表面接触的方向的运动的调节单元，直到通过清洁刮板对清洁表面的按压力不超过预定的按压力的位置。

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