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1. 发明申请

US20100152055A1 Composition and method for diagnosing kidney cancer and for predicting prognosis for kidney cancer patient 审中-公开
标题翻译：用于诊断肾癌和预测肾癌患者预后的组成和方法
公开(公告)号：US20100152055A1
公开(公告)日：2010-06-17
申请号：US11991297
申请日：2006-09-01
申请人： Satoko Kozono , Hideo Akiyama , Akira Myomoto , Yoshinori Tanaka , Giman Jung , Hitoshi Nobumasa , Osamu Nomura , Osamu Ogawa , Eijiro Nakamura , Gozo Tsujimoto
发明人： Satoko Kozono , Hideo Akiyama , Akira Myomoto , Yoshinori Tanaka , Giman Jung , Hitoshi Nobumasa , Osamu Nomura , Osamu Ogawa , Eijiro Nakamura , Gozo Tsujimoto
IPC分类号： C40B30/04 , C12Q1/68 , C40B40/06
CPC分类号： G01N33/57438 , C12Q1/6837 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118
摘要： This invention relates to a composition, kit, DNA chip, and use thereof for detecting, diagnosing, and predicting metastasis of kidney cancer and/or for predicting the prognosis for kidney cancer, comprising one or a plurality of polynucleotides selected from the group consisting of polynucleotides, mutants thereof or fragments thereof, the expression levels of which vary in kidney cancer cells from a patient with a poor prognosis when compared with that in kidney cancer cells from a patient with a good prognosis; or antibodies or fragments thereof that bind specifically to polypeptides, mutants thereof or fragments thereof, the expression levels of which vary in the similar manner.
摘要翻译：本发明涉及用于检测，诊断和预测肾癌转移和/或预测肾癌预后的组合物，试剂盒，DNA芯片及其用途，其包含一种或多种选自以下的多核苷酸：与具有良好预后的患者的肾癌细胞相比，其表达水平与预后不良的患者的肾癌细胞的表达水平不同; 或其特异性结合多肽，其突变体或其片段的抗体或其片段，其表达水平以相似的方式变化。

2. 发明授权

US07910316B2 Kit and method for detecting urothelial cancer 有权
标题翻译：用于检测尿路上皮癌的试剂盒和方法
公开(公告)号：US07910316B2
公开(公告)日：2011-03-22
申请号：US11991184
申请日：2006-09-01
申请人： Hideo Akiyama , Yoshinori Tanaka , Satoko Kozono , Hitoshi Nobumasa , Osamu Ogawa , Takeshi Takahashi
发明人： Hideo Akiyama , Yoshinori Tanaka , Satoko Kozono , Hitoshi Nobumasa , Osamu Ogawa , Takeshi Takahashi
IPC分类号： G01N33/53 , C12Q1/68
CPC分类号： G01N33/57407 , C12Q1/6886 , C12Q2600/112 , G01N33/57434 , G01N33/57438
摘要： This invention relates to a method for detecting in vitro a urothelial cancer, comprising measuring CXCL1 protein, or expression of a gene encoding the protein, in a biological sample from a subject, and to a kit for diagnosing a urothelial cancer comprising an antibody or nucleic acid probe, which is capable of binding specifically to the CXCL1 protein or a gene encoding the protein, respectively.
摘要翻译：本发明涉及体外检测尿路上皮癌的方法，其包括测量来自受试者的生物样品中的CXCL1蛋白或编码该蛋白的基因的表达，以及用于诊断包含抗体或核酸的尿路上皮癌的试剂盒酸探针，其能够分别特异性结合CXCL1蛋白或编码该蛋白的基因。

3. 发明申请

US20100009347A1 Kit and method for detecting urothelial cancer 有权
标题翻译：用于检测尿路上皮癌的试剂盒和方法
公开(公告)号：US20100009347A1
公开(公告)日：2010-01-14
申请号：US11991184
申请日：2006-09-01
申请人： Hideo Akiyama , Yoshinori Tanaka , Satoko Kozono , Hitoshi Nobumasa , Osamu Ogawa , Takeshi Takahashi
发明人： Hideo Akiyama , Yoshinori Tanaka , Satoko Kozono , Hitoshi Nobumasa , Osamu Ogawa , Takeshi Takahashi
IPC分类号： C12Q1/68 , G01N33/53 , G01N33/533 , G01N33/534 , G01N33/535
CPC分类号： G01N33/57407 , C12Q1/6886 , C12Q2600/112 , G01N33/57434 , G01N33/57438
摘要： This invention relates to a method for detecting in vitro a urothelial cancer, comprising measuring CXCL1 protein, or expression of a gene encoding the protein, in a biological sample from a subject, and to a kit for diagnosing a urothelial cancer comprising an antibody or nucleic acid probe, which is capable of binding specifically to the CXCL1 protein or a gene encoding the protein, respectively.
摘要翻译：本发明涉及体外检测尿路上皮癌的方法，其包括测量来自受试者的生物样品中的CXCL1蛋白或编码该蛋白的基因的表达，以及用于诊断包含抗体或核酸的尿路上皮癌的试剂盒酸探针，其能够分别特异性结合CXCL1蛋白或编码该蛋白的基因。

4. 发明申请

US20110045495A1 COMPOSITION AND METHOD FOR DIAGNOSIS OR DETECTION OF RENAL CANCER 审中-公开
标题翻译：用于诊断或检测肾癌的组合物和方法
公开(公告)号：US20110045495A1
公开(公告)日：2011-02-24
申请号：US12863396
申请日：2009-01-16
申请人： Yoshinori Tanaka , Michimoto Kobayashi , Shiori Tomoda , Giman Jung , Osamu Ogawa , Eijiro Nakamura
发明人： Yoshinori Tanaka , Michimoto Kobayashi , Shiori Tomoda , Giman Jung , Osamu Ogawa , Eijiro Nakamura
IPC分类号： G01N33/574 , C07K16/18
CPC分类号： C07K16/3038 , C07K14/47 , G01N33/57407 , G01N2333/4703 , G01N2333/4706 , G01N2333/4727
摘要： The present invention relates to a method for detection of a renal cancer, comprising measuring any one of or a plurality of polypeptides shown in SEQ ID NOS: 1-7, mutants thereof, or fragments thereof in a biological sample from a subject, and to a composition for diagnosis or detection of the renal cancer.
摘要翻译：本发明涉及肾癌的检测方法，包括测定来自受试者的生物样品中SEQ ID NO：1-7所示的任一种或多种多肽，其突变体或其片段，以及用于诊断或检测肾癌的组合物。

5. 发明申请

US20110287112A1 PROSTATE CANCER PROGRESSION INHIBITOR AND PROGRESSION INHIBITION METHOD 审中-公开
标题翻译：前列腺癌进展抑制剂和进展抑制方法
公开(公告)号：US20110287112A1
公开(公告)日：2011-11-24
申请号：US13147086
申请日：2010-01-29
申请人： Osamu Ogawa , Gozoh Tsujimoto , Eijiro Nakamura , Tomomi Kamba , Yosuke Shimizu , Naoki Terada , Toshiya Kanaji , Takayuki Maruyama
发明人： Osamu Ogawa , Gozoh Tsujimoto , Eijiro Nakamura , Tomomi Kamba , Yosuke Shimizu , Naoki Terada , Toshiya Kanaji , Takayuki Maruyama
IPC分类号： A61K33/24 , A61K31/573 , A61K31/566 , A61M37/00 , A61K31/337 , A61P35/00 , A61P5/28 , A61K31/277 , A61K38/09
CPC分类号： A61K31/277 , A61K45/06 , A61K2300/00
摘要： A prostate cancer progression inhibitor comprises 4-(4-cyano-2-{[2-(4-fluoro-1-naphthyl)propanoyl]amino}phenyl)butyric acid, a salt thereof, a solvate thereof, or a prodrug thereof. 4-(4-Cyano-2-{[2-(4-fluoro-1-naphthyl)propanoyl]amino}phenyl)butyric acid is useful as a prostate cancer progression inhibitor because this butyric acid has, for example, a growth inhibiting effect and a hormone responsiveness recovering effect on prostate cancer that has acquired hormone resistance.
摘要翻译：前列腺癌进展抑制剂包括4-（4-氰基-2 - {[2-（4-氟-1-萘基）丙酰基]氨基}苯基）丁酸，其盐，其溶剂合物或其前药。 4-（4-氰基-2 - {[2-（4-氟-1-萘基）丙酰基]氨基}苯基）丁酸可用作前列腺癌进展抑制剂，因为该丁酸具有例如生长抑制效应和激素反应恢复作用对获得激素抵抗的前列腺癌。

6. 发明授权

US08356713B2 Retainer and substrate storage container 有权
标题翻译：保持器和基板储存容器
公开(公告)号：US08356713B2
公开(公告)日：2013-01-22
申请号：US12741168
申请日：2008-10-30
申请人： Osamu Ogawa
发明人： Osamu Ogawa
IPC分类号： B65D85/48
CPC分类号： H01L21/67369
摘要： A retainer includes a frame, a pair of first elastic parts projected from a pair of opposing parts of the frame so as to approach to each other, and a second elastic part that is supported at the bent free ends of the paired first elastic parts to hold a substrate. The outside end of the second elastic part is positioned outside the free end of the first elastic part and closer to the opposing part of the frame. Also, first and second holds for holding the rim of the substrate are formed apart from each other. The second hold is positioned on the outer end side of the second elastic part from the first hold.
摘要翻译：保持器包括框架，从框架的一对相对部分突出以使得彼此接近的一对第一弹性部件和被支撑在成对的第一弹性部件的弯曲自由端处的第二弹性部件，握住底物。第二弹性部分的外端位于第一弹性部分的自由端的外侧并且更靠近框架的相对部分。此外，用于保持基板的边缘的第一和第二保持部彼此分开地形成。第二保持件从第一保持件定位在第二弹性部件的外端侧。

7. 发明申请

US20120269667A1 HERMETIC COMPRESSOR 审中-公开
标题翻译： HERMETIC压缩机
公开(公告)号：US20120269667A1
公开(公告)日：2012-10-25
申请号：US13497620
申请日：2011-08-10
申请人： Fuminori Sakima , Osamu Ogawa , Atsuo Okaichi , Noboru Iida , Shingo Oyagi
发明人： Fuminori Sakima , Osamu Ogawa , Atsuo Okaichi , Noboru Iida , Shingo Oyagi
IPC分类号： F04B17/03
CPC分类号： F04B39/04 , F04C18/356 , F04C23/008 , F04C23/02 , F04C29/0021 , F04C29/026 , F04C29/045 , F04C29/12 , F04C2240/807
摘要： A hermetic compressor (100) includes a closed casing (2), a compression mechanism (4), a motor (6), a discharge pipe (8), a first balance weight (18), a swirl flow generating portion (21), and a second balance weight (19). The motor (6) has a stator (14) and a rotor (15). A communication passage (20) is formed in the rotor (15) so as to introduce, into an upper space (7), a working fluid compressed in the compression mechanism (4) and discharged to a lower space (5) of the closed casing (2). A baffle plate (122) is provided as a discharge direction deflecting portion for causing the compressed working fluid to travel from the communication passage (20) to the upper space (7), while deflecting the working fluid in a direction inclined with respect to a direction parallel to a rotational axis O. The baffle plate (122) may be constituted by a part of the swirl flow generating portion (21).
摘要翻译：封闭式压缩机（100）包括封闭壳体（2），压缩机构（4），马达（6），排放管（8），第一平衡重（18），涡流产生部分（21），和第二平衡重（19）。电动机（6）具有定子（14）和转子（15）。连通通道（20）形成在转子（15）中，以便在上部空间（7）中将压缩机构（4）中压缩的工作流体引入到封闭的压缩机构（4）的下部空间（5）中套管（2）。设置挡板（122）作为排出方向偏转部分，用于使压缩的工作流体从连通通道（20）行进到上部空间（7），同时使工作流体沿相对于方向平行于旋转轴线O.挡板（122）可以由旋流产生部分（21）的一部分构成。

8. 发明授权

US07007262B2 High level synthesis method and apparatus 失效
公开(公告)号：US07007262B2
公开(公告)日：2006-02-28
申请号：US10291790
申请日：2002-11-12
申请人： Keiichi Kurokawa , Osamu Ogawa
发明人： Keiichi Kurokawa , Osamu Ogawa
IPC分类号： G06F17/50
CPC分类号： G06F17/5045
摘要： A behavioral description is converted to a CDFG. The CDFG is scheduled in such a way that the number of registers is minimized with a desired number of clock cycles. Hardware is allocated to the scheduled results. The minimum clock period (semi-synchronous minimum clock period) attainable by adjusting clock timings for allocated registers is determined. When the semi-synchronous minimum clock period is greater than a desired clock period, all the clock timings are reset to a same value and then the positions of the registers in the CDFG are so changed as to reduce the clock period. The processing returns to the step of determining the semi-synchronous minimum clock period when the performance is improved as a result of performing retiming, or otherwise is terminated.

9. 发明授权

US06711452B1 Semiconductor exposure apparatus and parameter check method 失效
标题翻译：半导体曝光装置及参数检查方法
公开(公告)号：US06711452B1
公开(公告)日：2004-03-23
申请号：US09610370
申请日：2000-07-05
申请人： Osamu Ogawa
发明人： Osamu Ogawa
IPC分类号： G06F1900
CPC分类号： G03F7/70525 , G03F7/70508
摘要： An apparatus adapted for exposing a semiconductor is controlled by a program using a plurality of parameters. The apparatus has an extraction device that extracts a parameter, from the plurality of parameters, of which a settable range is changed due to an upgrade of the program. An edit device edits a value of an extracted parameter extracted by the extraction device.
摘要翻译：适于暴露半导体的装置由使用多个参数的程序控制。该装置具有从多个参数中提取参数的提取装置，其中由于程序的升级可设置范围被改变。编辑装置编辑由提取装置提取的提取参数的值。

10. 外观设计

USD424559S Wireless telephone 失效
公开(公告)号：USD424559S
公开(公告)日：2000-05-09
申请号：US108120
申请日：1999-07-20
申请人： Osamu Ogawa
设计人： Osamu Ogawa

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