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    • 1. 发明申请
    • Prime Boost Vaccine for the Protection of Equines Against Equine Influenza
    • 保护马来流感流感疫苗
    • US20080292659A1
    • 2008-11-27
    • US12092164
    • 2006-10-27
    • Saskia Van De Zande
    • Saskia Van De Zande
    • A61K39/00A61P37/00
    • A61K39/145A61K39/12A61K2039/5254A61K2039/545A61K2039/552A61K2039/55511A61K2039/55577C12N2760/16134
    • The present invention is concerned with vaccinating equines against the equine influenza virus (EIV).It has now been found that adequate protection against equine influenza in equines can be achieved when vaccination with a live equine influenza vaccine (prime) is followed by vaccination with an inactivated influenza vaccine (boost), wherein the two shots are given no longer than 8 weeks apart.The present invention therefore provides a method for vaccination of animals against equine influenza, wherein an animal is first vaccinated with a (prime) vaccine comprising an attenuated equine influenza virus, followed by a vaccination with a (boost) vaccine comprising an inactivated equine influenza virus, and wherein the boost vaccine is administered no longer than eight weeks after the prime vaccine. Preferably the two shots are given no longer than 8 weeks apart, for example, between 3-6 weeks apart, preferably between 4-6 weeks apart.
    • 本发明涉及马匹与马流感病毒(EIV)接种疫苗。 现在已经发现,当用活马疹流感疫苗(初始)接种疫苗之后,用灭活的流感疫苗接种疫苗(升压),可以实现对马中的马流感的充分保护,其中两次射击不超过8次 相隔数周。 因此,本发明提供了一种针对马流感疫苗接种动物的方法,其中首先用包含减毒马流感病毒的(初级)疫苗接种动物,然后用包含灭活马流感病毒的(加强)疫苗接种疫苗 ,并且其中所述增强疫苗在所述主要疫苗之后不超过8周施用。 优选地,两次射击不超过8周,例如间隔3-6周,优选间隔4-6周。