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1. 发明申请

US20080299613A1 Compositions for degrading cellulosic material 有权
标题翻译：降解纤维素材料的组合物
公开(公告)号：US20080299613A1
公开(公告)日：2008-12-04
申请号：US12130838
申请日：2008-05-30
申请人： Sandra Merino , Keith McFarland , Joel Cherry , Sarah Teter
发明人： Sandra Merino , Keith McFarland , Joel Cherry , Sarah Teter
IPC分类号： C12P21/04 , C12N1/14 , C12N9/42 , C12P1/00
CPC分类号： C12N9/2437 , C07K14/37 , C12N9/2445 , C12P7/10 , C12P19/14 , C12P19/16 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： The present invention relates to cellulolytic compositions for degrading or converting cellulose-containing material and methods of producing and using the compositions.
摘要翻译：本发明涉及用于降解或转化含纤维素材料的纤维素分解组合物以及制备和使用该组合物的方法。

2. 发明授权

US09969993B2 Filamentous fungal host cells and methods of recombinantly producing proteins 有权
公开(公告)号：US09969993B2
公开(公告)日：2018-05-15
申请号：US12130838
申请日：2008-05-30
申请人： Sandra Merino , Keith McFarland , Joel Cherry , Sarah Teter
发明人： Sandra Merino , Keith McFarland , Joel Cherry , Sarah Teter
IPC分类号： A61K38/00 , C12N9/42 , C07K14/37 , C12P7/10 , C12P19/14 , C12P19/16
CPC分类号： C12N9/2437 , C07K14/37 , C12N9/2445 , C12P7/10 , C12P19/14 , C12P19/16 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： The present invention relates to cellulolytic compositions for degrading or converting cellulose-containing material and methods of producing and using the compositions.

3. 发明授权

US07741466B2 Polypeptides having cellulolytic enhancing activity and nucleic acids encoding same 有权
公开(公告)号：US07741466B2
公开(公告)日：2010-06-22
申请号：US12053193
申请日：2008-03-21
申请人： Kimberly Brown , Paul Harris , Elizabeth Zaretsky , Edward Re , Elena Vlasenko , Keith McFarland , Alfredo Lopez de Leon
发明人： Kimberly Brown , Paul Harris , Elizabeth Zaretsky , Edward Re , Elena Vlasenko , Keith McFarland , Alfredo Lopez de Leon
IPC分类号： C07H21/04 , C12P21/02 , C12N9/42
CPC分类号： C07K14/37 , C11D3/38645 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/2437 , C12N9/2445 , C12N15/52 , C12N15/63 , C12P7/14 , C12P19/02 , C12P19/14 , C12P2201/00 , C12P2203/00 , C12Y302/01021 , Y02E50/16 , Y02E50/17
摘要： The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.

4. 发明授权

US07361495B2 Polypeptide from a cellulolytic fungus having cellulolytic enhancing activity 有权
标题翻译：来自具有纤维素分解增强活性的纤维素分解真菌的多肽
公开(公告)号：US07361495B2
公开(公告)日：2008-04-22
申请号：US11046124
申请日：2005-01-28
申请人： Kimberly Brown , Paul Harris , Elizabeth Zaretsky , Edward Re , Elena Vlasenko , Keith McFarland , Alfredo Lopez de Leon
发明人： Kimberly Brown , Paul Harris , Elizabeth Zaretsky , Edward Re , Elena Vlasenko , Keith McFarland , Alfredo Lopez de Leon
IPC分类号： C12N9/42 , C12N9/14 , C07K14/37
CPC分类号： C07K14/37 , C11D3/38645 , C12N1/12 , C12N1/14 , C12N1/16 , C12N1/20 , C12N9/2437 , C12N9/2445 , C12N15/52 , C12N15/63 , C12P7/14 , C12P19/02 , C12P19/14 , C12P2201/00 , C12P2203/00 , C12Y302/01021 , Y02E50/16 , Y02E50/17
摘要： The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
摘要翻译：本发明涉及具有纤维素分解增强活性的分离的多肽和编码多肽的分离的多核苷酸。本发明还涉及包含多核苷酸的核酸构建体，载体和宿主细胞以及生产和使用多肽的方法。

5. 发明授权

US09544271B2 Anonymous messaging conversation 有权
标题翻译：匿名短信对话
公开(公告)号：US09544271B2
公开(公告)日：2017-01-10
申请号：US13610246
申请日：2012-09-11
申请人： Keith McFarland , Vishal Jain
发明人： Keith McFarland , Vishal Jain
IPC分类号： H04W4/00 , H04L29/12 , H04L12/58 , H04L29/06 , H04W4/12
CPC分类号： H04L61/2539 , H04L51/28 , H04L61/2525 , H04L63/0421 , H04L65/1069 , H04L65/1073 , H04W4/12
摘要： An anonymous communication module that provides full conversational anonymous messaging and voice/video communication between two or more parties interacting over a wireless/landline network. An anonymous messaging module accepts an anonymous initiation message to a public address to trigger the start of an anonymous voice/video conversation between a message originator and a message recipient. An anonymous communication module performs intercept and address substitution on a message and/or voice/video call transmitted between two or more parties via an anonymous communication service. The anonymous communication module substitutes a real address in the source field of an intercepted message and/or voice/video call, with an anonymous address mapped to that real address, and substitutes an anonymous address in the destination field of an intercepted message and/or voice/video call with a real address mapped to that anonymous address. The anonymous communication module then forwards the newly formatted message and/or voice/video call to an intended message/call destination.
摘要翻译：一种匿名通信模块，可在通过无线/固定电话网络交互的两个或多个方之间提供完全会话的匿名消息和语音/视频通信。匿名消息模块接受匿名发起消息到公共地址以触发消息发起者和消息接收者之间的匿名语音/视频对话的开始。匿名通信模块通过匿名通信服务在两个或多个方之间传送的消息和/或语音/视频呼叫上执行截取和地址替换。匿名通信模块将被拦截的消息和/或语音/视频呼叫的源字段中的真实地址替换为匿名地址映射到该真实地址，并且将被拦截消息的目的地字段中的匿名地址替换为/或使用映射到该匿名地址的实际地址进行语音/视频通话。匿名通信模块然后将新格式的消息和/或语音/视频呼叫转发到预期的消息/呼叫目的地。

6. 发明授权

US08883436B2 Method of analyzing cellulose decay in lignocellulosic material hydrolysis 有权
标题翻译：分析木质纤维素材料中纤维素衰变的方法
公开(公告)号：US08883436B2
公开(公告)日：2014-11-11
申请号：US13379555
申请日：2010-07-13
申请人： Marco Malten , Keith McFarland
发明人： Marco Malten , Keith McFarland
IPC分类号： C12Q1/34 , C12Q1/44
CPC分类号： C12Q1/34 , G01N2333/924
摘要： Enzymes and/or polypeptides and/or mixtures of interest are evaluated during hydrolysis of cellulosic material by the use of indicator constituents such as fluorescent agents, resulting in efficient high-throughput analysis of enzymes and/or polypeptides. A high-throughput assay for the analysis of inter alia, pretreated corn stover (PCS) hydrolysis is also disclosed.
摘要翻译：通过使用诸如荧光剂的指标成分，在纤维素材料的水解期间评估感兴趣的酶和/或多肽和/或混合物，从而导致酶和/或多肽的有效的高通量分析。还公开了用于分析预处理的玉米秸秆（PCS）水解的高通量分析。

7. 发明申请

US20130070672A1 Anonymous Messaging Conversation 有权
标题翻译：匿名消息传递对话
公开(公告)号：US20130070672A1
公开(公告)日：2013-03-21
申请号：US13610246
申请日：2012-09-11
申请人： Keith McFarland , Vishal Jain
发明人： Keith McFarland , Vishal Jain
IPC分类号： H04W4/12
CPC分类号： H04L61/2539 , H04L51/28 , H04L61/2525 , H04L63/0421 , H04L65/1069 , H04L65/1073 , H04W4/12
摘要： An anonymous communication module that provides full conversational anonymous messaging and voice/video communication between two or more parties interacting over a wireless/landline network. An anonymous messaging module accepts an anonymous initiation message to a public address to trigger the start of an anonymous voice/video conversation between a message originator and a message recipient. An anonymous communication module performs intercept and address substitution on a message and/or voice/video call transmitted between two or more parties via an anonymous communication service. The anonymous communication module substitutes a real address in the source field of an intercepted message and/or voice/video call, with an anonymous address mapped to that real address, and substitutes an anonymous address in the destination field of an intercepted message and/or voice/video call with a real address mapped to that anonymous address. The anonymous communication module then forwards the newly formatted message and/or voice/video call to an intended message/call destination.
摘要翻译：一种匿名通信模块，可在通过无线/固定电话网络交互的两个或多个方之间提供完整的会话式匿名消息和语音/视频通信。匿名消息模块接受匿名发起消息到公共地址以触发消息发起者和消息接收者之间的匿名语音/视频对话的开始。匿名通信模块通过匿名通信服务在两个或多个方之间传送的消息和/或语音/视频呼叫上执行截取和地址替换。匿名通信模块将被拦截的消息和/或语音/视频呼叫的源字段中的真实地址替换为匿名地址映射到该真实地址，并且将被拦截消息的目的地字段中的匿名地址替换为/或使用映射到该匿名地址的实际地址进行语音/视频通话。匿名通信模块然后将新格式的消息和/或语音/视频呼叫转发到预期的消息/呼叫目的地。

8. 发明授权

US09479344B2 Anonymous voice conversation 有权
标题翻译：匿名声音交谈
公开(公告)号：US09479344B2
公开(公告)日：2016-10-25
申请号：US13610192
申请日：2012-09-11
申请人： Keith McFarland , Vishal Jain
发明人： Keith McFarland , Vishal Jain
IPC分类号： G06F15/16 , H04L12/28 , H04L12/02 , H04L12/16 , H04M3/42 , H04L12/18 , H04M1/57 , H04L29/12 , H04L29/06 , H04L12/58
CPC分类号： H04L12/1818 , H04L29/12433 , H04L51/28 , H04L63/0407 , H04L63/0421 , H04M1/571 , H04M3/42008
摘要： An anonymous communication module that provides full conversational anonymous messaging and voice/video communication between two or more parties interacting over a wireless/landline network. An anonymous messaging module accepts an anonymous initiation message to a public address to trigger the start of an anonymous voice/video conversation between a message originator and a message recipient. An anonymous communication module performs intercept and address substitution on a message and/or voice/video call transmitted between two or more parties via an anonymous communication service. The anonymous communication module substitutes a real address in the source field of an intercepted message and/or voice/video call, with an anonymous address mapped to that real address, and substitutes an anonymous address in the destination field of an intercepted message and/or voice/video call with a real address mapped to that anonymous address. The anonymous communication module then forwards the newly formatted message and/or voice/video call to an intended message/call destination.
摘要翻译：一种匿名通信模块，可在通过无线/固定电话网络交互的两个或多个方之间提供完整的会话式匿名消息和语音/视频通信。匿名消息模块接受匿名发起消息到公共地址以触发消息发起者和消息接收者之间的匿名语音/视频对话的开始。匿名通信模块通过匿名通信服务在两个或多个方之间传送的消息和/或语音/视频呼叫上执行截取和地址替换。匿名通信模块将被拦截的消息和/或语音/视频呼叫的源字段中的真实地址替换为匿名地址映射到该真实地址，并且将被拦截消息的目的地字段中的匿名地址替换为/或使用映射到该匿名地址的实际地址进行语音/视频通话。匿名通信模块然后将新格式的消息和/或语音/视频呼叫转发到预期的消息/呼叫目的地。

9. 发明授权

US09453213B2 Methods of increasing the cellulolytic enhancing activity of a polypeptide 有权
标题翻译：增加多肽的纤维素分解增强活性的方法
公开(公告)号：US09453213B2
公开(公告)日：2016-09-27
申请号：US12598723
申请日：2008-05-30
申请人： Keith McFarland , Paul Harris
发明人： Keith McFarland , Paul Harris
IPC分类号： C12N9/14 , C12N9/42 , C12P1/00 , C07H21/04 , C12P7/10 , C12P19/02
CPC分类号： C12N9/2437 , C12N9/2445 , C12P7/10 , C12P19/02 , C12P19/14 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17 , Y02P20/52
摘要： The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.
摘要翻译：本发明涉及增加具有纤维素分解增强活性的多肽的活性的方法，包括：将可溶性活化二价金属阳离子加入到包含具有纤维素分解增强活性的多肽的组合物中，其中可溶性活化二价金属阳离子和具有纤维素分解增强活性的多肽与不含可溶性活化二价金属阳离子的具有纤维素分解增强活性的多肽相比，通过纤维素分解酶组合物增加了含纤维素材料的降解或转化。本发明还涉及组合物，降解或转化含纤维素材料的方法，以及用于生产发酵产物的方法。

10. 发明授权

US08999696B2 Compositions and methods for enhancing the degradation or conversion of cellulose-containing material 有权
标题翻译：用于增强含纤维素材料的降解或转化的组合物和方法
公开(公告)号：US08999696B2
公开(公告)日：2015-04-07
申请号：US12598574
申请日：2008-05-09
申请人： Keith McFarland
发明人： Keith McFarland
IPC分类号： C12N9/42 , C12P7/06
CPC分类号： C12P13/20 , C12N9/2437 , C12N9/2445 , C12P5/023 , C12P7/06 , C12P7/14 , C12P7/24 , C12P7/26 , C12P19/14 , C12P2201/00 , C12P2203/00 , C12Y302/01004 , C12Y302/01021 , C12Y302/01091 , Y02E50/16 , Y02E50/17 , Y02E50/343 , Y02P20/52
摘要： The present invention relates to methods for degrading or converting a cellulose-containing material, comprising: treating the cellulose-containing material with an effective amount of a cellulolytic enzyme composition comprising a polypeptide having cellulolytic enhancing activity, and one or more (several) components selected from the group consisting of a CEL7 polypeptide having endoglucanase activity, a CEL12 polypeptide having endoglucanase activity, a CEL45 polypeptide having endoglucanase activity, a CEL7 polypeptide having cellobiohydrolase activity with a cellulose binding domain, and a CEL7 polypeptide having cellobiohydrolase activity without a cellulose binding domain. The present invention also relates to such cellulolytic enzyme compositions.
摘要翻译：本发明涉及降解或转化含纤维素材料的方法，其包括：用有效量的包含具有纤维素分解增强活性的多肽的纤维素分解酶组合物和选择的一种或多种（多种）组分处理含纤维素材料由具有内切葡聚糖酶活性的CEL7多肽，具有内切葡聚糖酶活性的CEL12多肽，具有内切葡聚糖酶活性的CEL45多肽，具有纤维素结合结构域的纤维二糖水解酶活性的CEL7多肽和不含纤维素结合结构域的纤维二糖水解酶活性的CEL7多肽。本发明还涉及这种纤维素分解酶组合物。

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