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1. 发明申请

US20120052580A1 PEPTIDE-MODIFIED SURFACES FOR CELL CULTURE 审中-公开
标题翻译：细胞培养的肽修饰表面
公开(公告)号：US20120052580A1
公开(公告)日：2012-03-01
申请号：US13216621
申请日：2011-08-24
申请人： Sadashiva Karnire Pai , Odessa Natalie Petzold , Simon Kelly Shannon , David Michael Weber , Theresa Chang , Jin Liu
发明人： Sadashiva Karnire Pai , Odessa Natalie Petzold , Simon Kelly Shannon , David Michael Weber , Theresa Chang , Jin Liu
IPC分类号： C12N5/071 , C12N5/0797 , C12N5/0735 , C12N5/0793 , C12N5/079
CPC分类号： C08F8/30 , C12N5/0068 , C12N2533/30 , C12N2533/52 , C12N2533/54 , C08F222/06 , C08F210/10
摘要： A cell culture article including a pre-blocked, peptide-modified, polymer surface of the formula (I), where AAj represents at least one covalently bonded peptide, j is an integer of from 5 to 50, m, n, o, Sur, X, R, R′, and the mer ratio (m-o:n:o), including salts thereof, are as defined herein. Methods for making and using the cell culture article, as defined herein, are also disclosed.
摘要翻译：一种细胞培养物，其包含式（I）的预先封闭的，肽修饰的聚合物表面，其中AAj表示至少一个共价键合的肽，j为5-50的整数，m，n，o，Sur ，X，R，R'和聚合物比（mo：n：o）（包括其盐）如本文所定义。还公开了如本文定义的制备和使用细胞培养物品的方法。

2. 发明申请

US20110306136A1 LAMININ-ENTACTIN COMPLEX AND CELL CULTURE ARTICLE AND METHODS THEREOF 有权
标题翻译： LAMININ-ENTACTIN复合物和细胞培养物品及其方法
公开(公告)号：US20110306136A1
公开(公告)日：2011-12-15
申请号：US13111234
申请日：2011-05-19
申请人： Theresa Chang , Jin Liu , Odessa Natalie Petzold , Ruchirej Yongsunthon
发明人： Theresa Chang , Jin Liu , Odessa Natalie Petzold , Ruchirej Yongsunthon
IPC分类号： C12N5/071 , C12M3/00
CPC分类号： C12N5/0068 , C12M25/00 , C12N2533/50 , C12N2533/52
摘要： A cell culture system including: a substrate, a substrate coating, one or more live cells, and an overlay source. The substrate coating and overlay can be laminin, and laminin•entactin complex, respectively. Alternatively, the substrate coating and overlay can be laminin•entactin complex, and laminin, respectively. The cell culture system can further include liquid media and a protective cover. A method for making and using the system in cell culture articles and culture methods, as defined herein, is also disclosed.
摘要翻译：一种细胞培养系统，包括：底物，底物涂层，一个或多个活细胞和覆盖源。底物涂层和覆盖层可分别为层粘连蛋白和层粘连蛋白•内酰胺酶复合物。或者，基底涂层和覆盖层可以分别是层粘连蛋白·内含子复合物和层粘连蛋白。细胞培养系统还可以包括液体介质和保护盖。还公开了在本文定义的细胞培养物和培养方法中制备和使用该系统的方法。

3. 发明授权

US08513015B2 Laminin-entactin complex and cell culture article and methods thereof 有权
标题翻译：层粘蛋白 - 内含蛋白复合物和细胞培养物及其方法
公开(公告)号：US08513015B2
公开(公告)日：2013-08-20
申请号：US13111234
申请日：2011-05-19
申请人： Theresa Chang , Jin Liu , Odessa Natalie Petzold , Ruchirej Yongsunthon
发明人： Theresa Chang , Jin Liu , Odessa Natalie Petzold , Ruchirej Yongsunthon
IPC分类号： C12N5/00
CPC分类号： C12N5/0068 , C12M25/00 , C12N2533/50 , C12N2533/52
摘要： A cell culture system including: a substrate, a substrate coating, one or more live cells, and an overlay source. The substrate coating and overlay can be laminin, and laminin•entactin complex, respectively. Alternatively, the substrate coating and overlay can be laminin•entactin complex, and laminin, respectively. The cell culture system can further include liquid media and a protective cover. A method for making and using the system in cell culture articles and culture methods, as defined herein, is also disclosed.
摘要翻译：一种细胞培养系统，包括：底物，底物涂层，一个或多个活细胞和覆盖源。基底涂层和覆盖层可分别为层粘连蛋白和层粘连蛋白复合物。或者，基底涂层和覆盖层可以分别是层粘连蛋白复合物和层粘连蛋白。细胞培养系统还可以包括液体介质和保护盖。还公开了在本文定义的细胞培养物和培养方法中制备和使用该系统的方法。

4. 发明授权

US12063573B2 Method and device in communication nodes for wireless communication 有权
公开(公告)号：US12063573B2
公开(公告)日：2024-08-13
申请号：US18093819
申请日：2023-01-06
申请人： Jin Liu , Xiaobo Zhang
发明人： Jin Liu , Xiaobo Zhang
IPC分类号： H04W4/029 , H04L5/00 , H04W72/044
CPC分类号： H04W4/029 , H04L5/0048 , H04W72/044
摘要： Method and device in a node used for wireless communications. A first node receives first configuration information; transmits a first positioning reference signal on a first time-frequency resource block, transmits a second positioning reference signal on a second time-frequency resource block, and transmits a first information set; the first configuration information is used for indicating a first reference set, and any two time-frequency resource blocks in the first resource set employ a same positioning-related parameter; the first time-frequency resource block is earlier than the second time-frequency resource block in time domain; the first information set comprises a first distance, and the first distance refers to a distance from a first geographical position and a second geographical position, wherein the first geographical position is where the first node is located when transmitting the first positioning reference signal. The present disclosure provides an effective solution to the issue of sidelink positioning.

5. 发明授权

US11665648B2 Method and device in a node used for wireless communication 有权
公开(公告)号：US11665648B2
公开(公告)日：2023-05-30
申请号：US17864421
申请日：2022-07-14
申请人： Jin Liu , Xiaobo Zhang
发明人： Jin Liu , Xiaobo Zhang
IPC分类号： H04W52/32 , H04W52/14 , H04W52/36 , H04W76/27
CPC分类号： H04W52/325 , H04W52/143 , H04W52/367 , H04W76/27
摘要： The present disclosure provides a method and a device in a node used for wireless communication. A first node receives a first information element, the first information element being used for indicating a first reference power value; and receives a second information set, the second information set comprising a second information element, the second information element being used for indicating a second limit power value; and transmits a first radio signal with a first power value; a target receiver of the first radio signal includes a transmitter of the first information element, the first power value is related to a smaller value between the first reference power value and the second limit power value. Taking into account restrictions resulted from interference when adjusting a transmitting power of a desired signal, the present disclosure can address interferences that may occur in V2X system in unicast or groupcast transmission.

6. 发明授权

US11619499B2 Electric vehicle navigation method and system based on power guidance of energy-storage charging pile 有权
公开(公告)号：US11619499B2
公开(公告)日：2023-04-04
申请号：US16914447
申请日：2020-06-28
申请人： Tao Wei , Jingwen Huang , Jiaren Luo , Jin Liu
发明人： Tao Wei , Jingwen Huang , Jiaren Luo , Jin Liu
IPC分类号： G01C21/34 , B60L53/51 , B60L58/12 , B60L53/52
摘要： The present invention discloses a navigation method for electric vehicles based on electricity quantity guidance of energy-storage charging piles. The electric vehicles select charging piles nearby that can meet own charging quantity demands to charge according to location information of charging piles and real-time stored electricity information of energy storage modules of the charging piles; a system using the method includes the charging piles. The navigation method and system can reasonably guide the electric vehicles to charge according to the distribution and the stored electricity of the charging piles, and can dynamically plan travel charging solutions for the electric vehicles, thereby avoiding problems that the electric vehicles stop running without electricity on the way to the charging piles and inefficiently wait for charging for a long time, so that the stored electricity of the charging piles can be reasonably distributed and utilized, and energy idleness and waste are avoided.

7. 发明授权

US11501545B2 Smart microscope system for radiation biodosimetry 有权
公开(公告)号：US11501545B2
公开(公告)日：2022-11-15
申请号：US17137317
申请日：2020-12-29
申请人： Peter Keith Rogan , Yanxin Li , Jin Liu
发明人： Peter Keith Rogan , Yanxin Li , Jin Liu
IPC分类号： G06V20/69 , G06T5/50 , G01T1/02 , G06T5/00
摘要： Automation of microscopic pathological diagnosis relies on digital image quality, which, in turn, affects the rates of false positive and negative cellular objects designated as abnormalities. Cytogenetic biodosimetry is a genotoxic assay that detects dicentric chromosomes (DCs) arising from exposure to ionizing radiation. The frequency of DCs is related to radiation dose received, so the inferred radiation dose depends on the accuracy of DC detection. To improve this accuracy, image segmentation methods are used to rank high quality cytogenetic images and eliminate suboptimal metaphase cell data in a sample based on novel quality measures. When sufficient numbers of high quality images are found, the microscope system is directed to terminate metaphase image collection for a sample. The International Atomic Energy Agency recommends at least 500 images be used to estimate radiation dose, however often many more images are collected in order to select the metaphase cells with good morphology for analysis. Improvements in DC recognition increase the accuracy of dose estimates, by reducing false positive (FP) DC detection. A set of chromosome morphology segmentation methods selectively filtered out false DCs, arising primarily from extended prometaphase chromosomes, sister chromatid separation and chromosome fragmentation. This reduced FPs by 55% and was highly specific to the abnormal structures (≥97.7%). Additional procedures were then developed to fully automate image review, resulting in 6 image-level filters that, when combined, selectively remove images with consistently unparsable or incorrectly segmented chromosome morphologies. Overall, these filters can eliminate half of the FPs detected by manual image review. Optimal image selection and FP DCs are minimized by combining multiple feature based segmentation filters and a novel image sorting procedure based on the known distribution of chromosome lengths. Consequently, the average dose estimation error was reduced from 0.4 Gy to

8. 发明授权

US11445449B2 Power control method and device to trade off desired signal power and interference among multiple wireless devices 有权
公开(公告)号：US11445449B2
公开(公告)日：2022-09-13
申请号：US16799847
申请日：2020-02-25
申请人： Jin Liu , XiaoBo Zhang
发明人： Jin Liu , XiaoBo Zhang
IPC分类号： H04W52/32 , H04W76/27 , H04W52/36 , H04W52/14
摘要： A method and a device in a node used for wireless communication are proposed. A first node receives a first information element, the first information element being used for indicating a first reference power value; and receives a second information set, the second information set comprising a second information element, the second information element being used for indicating a second limit power value; and transmits a first radio signal with a first power value; a target receiver of the first radio signal includes a transmitter of the first information element, the first power value is related to a smaller value between the first reference power value and the second limit power value. Taking into account restrictions resulted from interference when adjusting a transmitting power of a desired signal, interferences that may occur in V2X system in unicast or groupcast transmission are addressed.

9. 发明授权

US09243009B2 Phosphate ester compound of hydroxy acid substituted phenol ester, preparation method and medical use thereof 有权
标题翻译：羟基酸取代苯酚酯的磷酸酯化合物，其制备方法和医疗用途
公开(公告)号：US09243009B2
公开(公告)日：2016-01-26
申请号：US13702204
申请日：2010-10-13
申请人： Wensheng Zhang , Jun Yang , Jin Liu
发明人： Wensheng Zhang , Jun Yang , Jin Liu
IPC分类号： C07F9/09
CPC分类号： C07F9/09 , C07F9/091
摘要： Phosphate ester compound of hydroxy acid substituted phenyl ester, preparation method and medical use thereof are provided. The title compound is shown in formula (I), in which Y═C1-4 straight carbon chain, M1 and/or M2=H, alkali metal ion, protonated amine or protonated amino acid. The compound has good water solubility and high stability in its aqueous solution, and it can release 2,6-diisopropylphenol rapidly under the action of enzymes in vivo, which has the effects of sedation, hypnosis and/or anesthesia. By protecting hydroxyl of 2,6-diisopropylphenol in compound of formula (I), the first-pass metabolic activity of 2,6-diisopropylphenol is reduced, so that the synthetic compound can be used for sedation, hypnosis and/or anesthesia.
摘要翻译：提供羟基酸取代苯基酯的磷酸酯化合物，其制备方法和医疗用途。标题化合物如式（I）所示，其中Y = C1-4直碳链，M1和/或M2 = H，碱金属离子，质子化胺或质子化氨基酸。该化合物在其水溶液中具有良好的水溶性和高稳定性，并且可以在体内酶的作用下快速释放2,6-二异丙基苯酚，其具有镇静，催眠和/或麻醉的作用。通过保护式（I）化合物中2,6-二异丙基苯酚的羟基，2,6-二异丙基苯酚的首过代谢活性降低，合成化合物可用于镇静，催眠和/或麻醉。

10. 发明授权

US08739256B2 Method for providing access to a service 有权
标题翻译：提供服务访问的方法
公开(公告)号：US08739256B2
公开(公告)日：2014-05-27
申请号：US13121273
申请日：2008-10-08
申请人： Uwe Foell , Jin Liu
发明人： Uwe Foell , Jin Liu
IPC分类号： G06F7/04 , G06F15/16 , G06F17/30 , H04L29/06
CPC分类号： H04L63/08 , G06F21/41 , H04L63/0815
摘要： A system is described comprising a service provider and an identity provider. A user requests access to the service provider and the service provider seeks user credentials from the identity provider. In use, the service provider issues an authentication request, which request specifies details of a plurality of acceptable authentication formats. The identity provider responds to the request either by providing authentication details for said user in one of the formats specified in the request, or by returning an error message indicating that it cannot support any of the specified authentication formats.
摘要翻译：描述了包括服务提供商和身份提供者的系统。用户请求对服务提供商的访问，并且服务提供商从身份提供商寻求用户凭证。在使用中，服务提供商发出认证请求，该请求指定多个可接受的认证格式的细节。身份提供者通过以请求中指定的格式之一提供所述用户的身份验证细节，或通过返回指示其不能支持任何指定的认证格式的错误消息来响应该请求。

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