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1. 发明公开

US20240157045A1 DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：US20240157045A1
公开(公告)日：2024-05-16
申请号：US18281784
申请日：2022-03-08
申请人： SENSILE MEDICAL AG
发明人： PEER KOSTAL , MATTHIAS MÜLLER
IPC分类号： A61M5/155 , A61M5/142 , A61M5/24 , A61M5/315
CPC分类号： A61M5/155 , A61M5/14212 , A61M5/14248 , A61M5/2455 , A61M5/31513 , A61M2205/3331
摘要： A drug delivery device (1), comprising a delivery unit (3) including a drug container (6), a liquid flow system (7), a pressurized gas source, and a casing (9) enclosing therein the drug container, the pressurized gas source and at least a part of the liquid flow system, the drug container comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, the drug container being contained within a container receiving cavity (75) of a container casing portion (38) of the casing (9) and the container receiving cavity is fluidically interconnected to a fluid outlet (31) of the pressurized gas source in a gas tight manner, the pressurized gas source configured to supply pressurized gas in the container receiving cavity (75) thus applying pressure on a back end (73) of the plunger for delivery of the liquid drug. The drug delivery device further comprises a pressure sensor (80) fluidically coupled to the container casing (38) for measuring a pressure within the container casing (38), the pressure sensor connected to an electronic control system (47) configured to measure a pressure detected by the pressure sensor over time and to determine from the pressure measurement over time a position of the plunger over time, including a stop in movement of the plunger either due to occlusion in the drug delivery flow system or an end of travel of the plunger within a container corresponding to a container empty position.

2. 发明公开

US20240082486A1 DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：US20240082486A1
公开(公告)日：2024-03-14
申请号：US18462457
申请日：2023-09-07
申请人： SENSILE MEDICAL AG
发明人： PASCAL LAGORGETTE , FABIAN BÜRLI , MATTHIAS MÜLLER , PEER KOSTAL
IPC分类号： A61M5/142
CPC分类号： A61M5/14248 , A61M2202/0007
摘要： A drug delivery device (1), comprising a delivery unit (3) including a drug container (6) comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, and a drive unit (4) comprising a pneumatic flow system (74) and a pneumatic pumping system configured to pump air via the pneumatic flow system (74) to a space behind the plunger to generate a gas pressure to advance the plunger in the container during drug delivery. The drug delivery device comprises a sealing adaptor (9) mounted on an end of the drug container facing an outer side of the plunger, the sealing adaptor (9) comprising a sealing plug (23) inserted inside an end of the barrel portion, the sealing plug (23) comprising an orifice (26) configured for pluggable sealing connection to a gas channel connector (40) of the pneumatic flow system.

3. 发明公开

US20240175431A1 MICROPUMP 审中-公开
公开(公告)号：US20240175431A1
公开(公告)日：2024-05-30
申请号：US18389242
申请日：2023-11-14
申请人： SENSILE MEDICAL AG
发明人： MATTHIAS MÜLLER
IPC分类号： F04B19/00
CPC分类号： F04B19/006
摘要： A pump (1) comprising a stator (4) and a rotor (6) axially and rotatably movable relative to the stator, the stator (4) comprising a piston chamber (10) comprising a radial surface (30), an inlet (3) comprising an inlet mouth (28) formed in the radial surface and an outlet (5) comprising an outlet mouth (29) formed in the radial surface, the rotor (6) comprising a piston portion (13) comprising a radial surface (16), an end face (15) and a non-axisymmetric indent (14) formed between the radial surface (16) and the end face (15) of the piston portion (13), wherein the indent (14) is arranged to overlap at least partially the inlet mouth (28) over a range of angular positions of the rotor relative to the stator corresponding to a pump intake phase, and arranged to overlap at least partially the outlet mouth (29) over a range of angular positions of the rotor relative to the stator corresponding to a pump expel phase, and wherein the radial surface (16) of the piston portion (13) is configured to close the outlet mouth (29) during the pump intake phase, the inlet mouth (28) during the pump expel phase and both the inlet and outlet mouths (28) between the pump intake and expel phases. The stator (4) comprises a flexible elastic membrane (7) sealingly separating the piston portion (13) from the piston chamber (10).

4. 发明公开

US20240066541A1 PUSH ACTUATED DOUBLE FLUID DISPENSER 审中-公开
公开(公告)号：US20240066541A1
公开(公告)日：2024-02-29
申请号：US18451881
申请日：2023-08-18
申请人： SENSILE MEDICAL AG
发明人： ALEXANDRE PERRIER , CHRISTIAN HUBER , MATTHIAS MÜLLER
IPC分类号： B05B11/10
CPC分类号： B05B11/1084 , B05B11/1028 , B05B11/1053
摘要： Push actuated double fluid dispenser (1), comprising a container (2) having a first cavity (4a) and a second cavity (4b) separated from the cap first cavity (4a), and a dispensing pump device (6) in a general form of a cap assembled to the container over the first and second cavities, the dispensing pump device comprising a base part (7) and a cap part (8) including a pump mechanism (16) comprising an elastic flexible pump membrane (18) manually movable from an uncompressed state to a compressed state. The pump mechanism (16) further comprises a separating wall (20) extending from an underside of the pump membrane (18) and inserted into a slot in the base part, the separating wall separating a first pump chamber (22a) from a second pump chamber (22b), both first and second pump chambers provided in a volume below the pump membrane (18), the first pump chamber connected fluidically to a first inlet channel (10a) and a first outlet channel (11a), the second pump chamber connected fluidically to a second inlet channel (10b) and second outlet channel (11b), the inlet channels fluidically interconnecting the respective first and second cavities to the respective first and second pump chambers, valves (13) being positioned between the inlet channels and the pump chambers configured to allow fluid flow only in the direction from the cavities to the respective pump chambers, and the outlet channels interconnecting the pump chambers to an outlet nozzle (12) of the dispenser, outlet valves (24a, 24b) being positioned in the outlet channels configured to allow fluid flow only in the direction from the pump chambers to the outlet nozzle.

5. 发明公开

US20240033423A1 DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：US20240033423A1
公开(公告)日：2024-02-01
申请号：US18282248
申请日：2022-03-08
申请人： SENSILE MEDICAL AG
发明人： MATTHIAS MÜLLER , CHRISTIAN HUBER , FABIAN BÜRLI , ALEXANDRE PERRIER
IPC分类号： A61M5/145 , A61M5/142 , A61M5/14
CPC分类号： A61M5/14526 , A61M5/14248 , A61M5/1413 , A61M5/1456 , A61M2005/14252 , A61M2005/1401 , A61M2005/14268 , A61M2005/14573 , A61M2202/0007 , A61M2202/04 , A61M2205/13 , A61M2205/10 , A61M2205/073 , A61M2205/123 , A61M2205/3306
摘要： A drug delivery device (1), comprising a delivery unit (3) including a drug container (6), a liquid flow system (7), a pumping system (8), and a casing (9) enclosing therein the drug container, the pumping system and at least a part of the liquid flow system, the drug container comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, the liquid flow system (7) connected fluidically to the drug container during delivery of the liquid drug. The drug container is contained within a container receiving cavity (75) of a container casing portion (38) of the casing (9) and the container receiving cavity is fluidically interconnected to a fluid outlet (31) of the pumping system (8) in a gas tight manner, the pumping system comprising a fluid inlet (30) connected to environmental air, the pumping system configured to pump environmental air drawn in through the fluid inlet (30) into the container receiving cavity (75) thus applying pressure on a back end (73) of the plunger for delivery of the liquid drug.

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