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1. 发明授权

US4040906A Method of producing carbon source for citric acid fermentation 失效
标题翻译：生产柠檬酸发酵碳源的方法
公开(公告)号：US4040906A
公开(公告)日：1977-08-09
申请号：US679711
申请日：1976-04-23
申请人： Ryosuke Uchio , Kenji Kikuchi , Soichiro Asai , Kenichi Yarita
发明人： Ryosuke Uchio , Kenji Kikuchi , Soichiro Asai , Kenichi Yarita
IPC分类号： C12P7/48 , C13K3/00 , C12D1/04 , C12B3/04
CPC分类号： C13K3/00 , C12P7/48 , Y10S435/914 , Y10S435/917
摘要： A sugar hydrolyzate, containing both glucose and fructose, is mixed with calcium hydroxide, and a fructose addition precipitate is recovered. The residual liquor is neutralized, calcium ions are removed, and then the liquor is used as a carbon source for citric acid fermentation.The present method may supply very inexpensive fructose to the market.
摘要翻译：含有葡萄糖和果糖的糖水解物与氢氧化钙混合，回收果糖加成沉淀。残留的液体被中和，除去钙离子，然后将该液体用作柠檬酸发酵的碳源。

2. 发明授权

US4966994A Method for purifying L-glutamine 失效
标题翻译： L-谷氨酰胺的纯化方法
公开(公告)号：US4966994A
公开(公告)日：1990-10-30
申请号：US378042
申请日：1989-07-11
申请人： Masashi Miyazawa , Toyokazu Kaneko , Tetsuya Kaneko , Kenichi Yarita
发明人： Masashi Miyazawa , Toyokazu Kaneko , Tetsuya Kaneko , Kenichi Yarita
IPC分类号： C12P13/14 , C07C231/24
CPC分类号： C07C231/24
摘要： L-glutamine is purified by concentrating a fermentation liquor containing at least 40 g/l or more of L-glutamine, or a solution obtained therefrom by filtering off microbial cells, at pH 5.6.+-.0.5, or by cooling the fermentation liquor or the solution after concentration or without concentration at a temperature in the range of 2.degree. to 30.degree. C., thereby giving a slurry of L-glutamine crystals of 70 g/l or higher concentration; (2) separating the crystals from the mother liquor and then dissolving the separated crystals in a water; and (3) bringing the solution thus obtained into contact with an OH-type anion-exchange resin, thereby removing impurities through adsorption.

3. 发明授权

US5070208A Method for crystallization of optically active tryptophan 失效
标题翻译：光学活性色氨酸结晶方法
公开(公告)号：US5070208A
公开(公告)日：1991-12-03
申请号：US670182
申请日：1991-03-15
申请人： Kenichi Yarita , Takahisa Tada , Ryuichiro Kasatani
发明人： Kenichi Yarita , Takahisa Tada , Ryuichiro Kasatani
IPC分类号： C07D209/20
CPC分类号： C07D209/20
摘要： Optically active tryptophan is crystallized by a modification of a method of crystrallization of optically active tryptophan through neutralization by mixing an acidic or alkaline aqueous solution of optically active tryptophan, which is obtained by the removal of impurities from an acidic or alkaline aqueous solution of optically active tryptophan containing impurities which inhibit flocculation and crystallization of optically active tryptophan, with an alkali or an acid, by combining portions of an alkali or acid with portions of an acidic or alkaline aqueous solution of optically active tryptophan, from which the impurities have been removed, thereby neutralizing the aqueous solution containing optically active tryptophan such that the pH of the solution to be crystallized is kept in a range of 3 to 8, and simultaneously crystallizing optically active tryptophan as flocculated crystals.
摘要翻译：通过将光学活性色氨酸的酸性或碱性水溶液通过从光学活性的酸性或碱性水溶液中除去杂质获得的光学活性色氨酸水溶液，通过中和来改变光学活性色氨酸的冷冻方法，使光学活性色氨酸结晶化含有杂质的色氨酸，其通过将碱或酸的一部分与已经除去杂质的酸性或碱性光学活性色氨酸水溶液的部分组合而抑制光学活性色氨酸的絮凝和结晶，用碱或酸，从而中和含有光学活性色氨酸的水溶液，使得待结晶的溶液的pH保持在3至8的范围内，同时使旋光色氨酸作为絮凝晶体结晶。

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