专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070148702A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译：用于表面等离子体共振生物传感器的测量芯片及其生产方法
公开(公告)号：US20070148702A1
公开(公告)日：2007-06-28
申请号：US11683192
申请日：2007-03-07
申请人： Runa NAKAMURA , Hiroyuki Nakamura , Ryohei Nagata , Isao Karube , Hitoshi Muguruma
发明人： Runa NAKAMURA , Hiroyuki Nakamura , Ryohei Nagata , Isao Karube , Hitoshi Muguruma
IPC分类号： G01N33/53 , C12M1/34
CPC分类号： G01N21/553
摘要： An objective of the present invention is to provide a measuring chip for a surface plasmon resonance sensor that can detect a small amount of target substances in high sensitivity. The present invention provides a measuring chip for a surface plasmon resonance sensor comprising a metal layer, one or more plasma polymerization layers formed on said metal layer, and a biologically active substance immobilized on the surface of said plasma polymerization layer.
摘要翻译：本发明的目的是提供一种能够以高灵敏度检测少量目标物质的表面等离子体共振传感器的测量芯片。本发明提供了一种用于表面等离子体共振传感器的测量芯片，其包括金属层，在所述金属层上形成的一个或多个等离子体聚合层和固定在所述等离子体聚合层的表面上的生物活性物质。

2. 发明授权

US6104484A Measuring chip for optical analyzer 失效
标题翻译：光学分析仪测量芯片
公开(公告)号：US6104484A
公开(公告)日：2000-08-15
申请号：US44847
申请日：1998-03-20
申请人： Ryohei Nagata , Hiroyuki Nakamura
发明人： Ryohei Nagata , Hiroyuki Nakamura
IPC分类号： G01N21/64 , G01N1/28 , G01N21/03 , G01N21/27 , G01N21/31 , G01N21/41 , G01N33/543 , G01N1/10 , G01N21/00
CPC分类号： G01N21/553
摘要： A measuring chip for an optical analyzer includes a translucent or transparent substrate 1, and a sample solution chamber S formed on a sulface of the translucent or transparent substrate 1. The sample solution chamber S has an inlet S.sub.1 for introducing a sample solution to be analyzed, and an outlet S.sub.2 for discharging the analyzed sample solution. The sample solution chamber S is formed so as to be filled with the sample solution between the inlet S.sub.1 and the vicinity of the outlet S.sub.2 by the capillary phenomenon. On the translucent or transparent substrate 1, an analyzing region 10 is formed by stacking a metal thin film 2 and an immobilizing film 3 for immobilizing a physiologically active substance 4. On the analyzing region 10, the sample solution chamber S is formed to obtain a measuring chip for an optical analyzer particularly utilizing the surface plasmon resonance (SPR). Thus. it, is possible to obtain a measuring chip for an optical analyzer, which can be easily handled and which can carry out an analysis using a small quantity of sample solution.
摘要翻译：用于光学分析仪的测量芯片包括半透明或透明基板1和形成在半透明或透明基板1的表面上的样品溶液室S.样品溶液室S具有用于引入待分析样品溶液的入口S1 ，以及用于排出所分析的样品溶液的出口S2。样品溶液室S形成为通过毛细管现象填充入口S1和出口S2附近的样品溶液。在半透明或透明基板1上，通过堆叠用于固定生理活性物质4的金属薄膜2和固定膜3来形成分析区域10.在分析区域10上，形成样品溶液室S，用于特别利用表面等离子体共振（SPR）的光学分析仪的测量芯片。从而。可以获得可以容易地处理并且可以使用少量样品溶液进行分析的光学分析仪的测量芯片。

3. 发明授权

US06627397B1 Measuring chip for surface plasmon resonance biosensor and method for producing the same 失效
公开(公告)号：US06627397B1
公开(公告)日：2003-09-30
申请号：US09274321
申请日：1999-03-23
申请人： Runa Nakamura , Hiroyuki Nakamura , Ryohei Nagata , Isao Karube , Hitoshi Muguruma
发明人： Runa Nakamura , Hiroyuki Nakamura , Ryohei Nagata , Isao Karube , Hitoshi Muguruma
IPC分类号： C12Q168
CPC分类号： G01N21/553
摘要： An objective of the present invention is to provide a measuring chip for a surface plasmon resonance sensor that can detect a small amount of target substances in high sensitivity. The present invention provides a measuring chip for a surface plasmon resonance sensor comprising a metal layer, one or more plasma polymerization layers formed on said metal layer, and a biologically active substance immobilized on the surface of said plasma polymerization layer.

4. 发明授权

US06391546B1 Method for detecting target nucleotide sequence 有权
标题翻译：检测靶核苷酸序列的方法
公开(公告)号：US06391546B1
公开(公告)日：2002-05-21
申请号：US09147251
申请日：1998-11-12
申请人： Isao Karube , Shinya Sawata , Ryohei Nagata
发明人： Isao Karube , Shinya Sawata , Ryohei Nagata
IPC分类号： C12Q168
CPC分类号： C12Q1/6832 , C12Q1/686 , C12Q2531/107 , C12Q2565/501
摘要： An object of the present invention is to provide a method for detecting a target nucleotide sequence using a complementary nucleotide sequence that has an excellent sensitivity of detection. The method comprises the steps of converting the target nucleotide sequence to a partially double-stranded nucleotide sequence which is double-stranded at one part and single-stranded in the remaining part and detecting said partially double stranded nucleotide sequence using a nucleotide sequence that is complementary to the target nucleotide sequence.
摘要翻译：本发明的目的是提供使用检测灵敏度优异的互补核苷酸序列检测靶核苷酸序列的方法。该方法包括以下步骤：将目标核苷酸序列转化为部分双链核苷酸序列，其一部分为双链，其余部分为单链，并使用互补的核苷酸序列检测所述部分双链核苷酸序列到目标核苷酸序列。

5. 发明授权

US5804047A Enzyme-immobilized electrode, composition for preparation of the same and electrically conductive enzyme 失效
标题翻译：固定酶的电极，用于制备相同导电性酶的组合物
公开(公告)号：US5804047A
公开(公告)日：1998-09-08
申请号：US357987
申请日：1994-12-16
申请人： Isao Karube , Susan Anne Clark , Ryohei Nagata
发明人： Isao Karube , Susan Anne Clark , Ryohei Nagata
IPC分类号： C12Q1/00 , G01N27/26
CPC分类号： C12Q1/005 , C12Q1/003 , C12Q1/004 , Y10S435/817
摘要： An enzyme sensor system capable of quantitatively determining a particular component contained in a biological sample in a rapid and easy manner is disclosed. More particularly, an electrically conductive enzyme, an enzyme-immobilized electrode using the same and a composition for use in the preparation of the enzyme electrode are disclosed. The composition for an enzyme-immobilized electrode according to the present invention enables electrodes of various patterns to be produced by screen printing.
摘要翻译：公开了能够以快速和容易的方式定量测定生物样品中所含的特定组分的酶传感器系统。更具体地，公开了导电酶，使用该电极的酶固定电极和用于制备酶电极的组合物。根据本发明的酶固定化电极的组合物能够通过丝网印刷制造各种图案的电极。

6. 发明授权

US5246664A Water-disintegrable material and device for assaying a body fluid 失效
标题翻译：水消毒材料和用于测定身体液体的装置
公开(公告)号：US5246664A
公开(公告)日：1993-09-21
申请号：US651252
申请日：1991-05-20
申请人： Ryohei Nagata , Tskeshi Saito , Tetsuya Fujiwara , Motohiro Oka , Masanao Watanabe
发明人： Ryohei Nagata , Tskeshi Saito , Tetsuya Fujiwara , Motohiro Oka , Masanao Watanabe
IPC分类号： C08L29/14 , C08L39/06 , C09D129/14 , C09D139/06 , D21H13/04 , D21H19/20 , D21H19/56 , D21H19/60 , G01N31/22 , G01N33/52 , G01N33/545 , G01N33/548
CPC分类号： C09D129/14 , C09D139/06 , D21H13/04 , D21H19/20 , D21H19/56 , D21H19/60 , G01N31/22 , G01N33/521 , G01N33/525 , G01N33/545 , G01N33/548 , C08L29/14 , C08L39/06 , Y10S435/805
摘要： A water-disintegrable support paper material largely formed of fibrous carboxymethylcellulose or carboxyethylcellulose having a degree of etherification of 0.1 to 1.0 and a degree of base saturation of 20% or more. A solution or dispersion of that paper has a pH of 5.0 to 8.0. There is also disclosed a composition for forming a water-disintegrable coat for coating on the support, the composition being a mixture of (a) at least one water-insoluble resin capable of forming a film having a saturation hygroscopicity less than 15% at a 90% relative humidity, (b) at least one water-soluble resin capable of forming film having a saturation hygroscopicity of 15% or more at a 90% relative humidity, and (c) a solvent in which both the resins (a) and (b) can dissolve. Lastly, there is disclosed a device for assaying a body fluid obtained by providing a body fluid assay reagent layer on at least a part of the coat on the support material, giving the device improved maneuverability and toughness during inspection and improved disintegrability after use.
摘要翻译： PCT No.PCT / JP90 / 00976 Sec。 371日期1991年5月20日 102（e）日期1991年5月20日PCT提交1990年7月31日PCT公布。公开号WO91 / 02249 日期1991年2月21日。一种水解性支撑纸材料，主要由醚化程度为0.1〜1.0，碱饱和度为20％以上的纤维状羧甲基纤维素或羧乙基纤维素形成。该纸的溶液或分散体的pH为5.0-8.0。还公开了一种用于在载体上形成用于涂覆的水解崩解涂层的组合物，该组合物是（a）至少一种能够形成具有小于15％的饱和吸湿性的膜的至少一种水不溶性树脂的混合物 90％相对湿度下，（b）能够在90％相对湿度下形成饱和吸湿性为15％以上的膜的至少一种水溶性树脂，和（c）其中树脂（a）和（b）可溶解。最后，公开了一种通过在载体材料的至少一部分涂层上提供体液测定试剂层而获得的体液测定装置，使得在使用时提高了检查时的机动性和韧性，提高了使用后的崩解性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式