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1. 发明授权

US07879108B2 Prosthetic repair fabric with erosion resistant edge 有权
标题翻译：假面修补面料具有抗侵蚀边缘
公开(公告)号：US07879108B2
公开(公告)日：2011-02-01
申请号：US10933080
申请日：2004-09-02
申请人： Valerie Vadurro , Stephen N. Eldridge , Michael J. Lee , Roger E. Darois
发明人： Valerie Vadurro , Stephen N. Eldridge , Michael J. Lee , Roger E. Darois
IPC分类号： A61F2/02
CPC分类号： A61F2/0063 , A61F2/0077
摘要： An implantable prosthesis is provided for repairing or augmenting anatomical weaknesses or defects, and is particularly suitable for the repair of soft tissue and muscle wall openings. The prosthesis may include a repair fabric that is constructed and arranged to allow tissue ingrowth and is susceptible to erosion into and the formation of adhesions with tissue and organs. One or more regions of the prosthesis may be configured to inhibit erosion into and/or the formation of adhesions with tissue and organs. The prosthesis may include an erosion resistant edge to buffer an edge of the fabric from the adjacent tissue or organs. The erosion resistant edge may be provided along an opening that is adapted to receive a tube-like structure, such as the esophagus.
摘要翻译：为可修复或增加解剖缺陷或缺陷提供可植入假体，并且特别适用于修复软组织和肌肉壁开口。假体可以包括构造和布置成允许组织向内生长并且易于侵蚀和与组织和器官形成粘连的修复织物。假体的一个或多个区域可以被配置为抑制对组织和器官的粘连的侵蚀和/或形成粘连。假体可以包括抗侵蚀边缘以从邻近的组织或器官缓冲织物的边缘。抗侵蚀边缘可以沿着适于接收管状结构（例如食道）的开口设置。

2. 发明授权

US06736823B2 Prosthetic repair fabric 有权
公开(公告)号：US06736823B2
公开(公告)日：2004-05-18
申请号：US10143564
申请日：2002-05-10
申请人： Roger E. Darois , Stephen N. Eldridge , Michael J. Lee
发明人： Roger E. Darois , Stephen N. Eldridge , Michael J. Lee
IPC分类号： A61F202
CPC分类号： A61F2/0063 , A61B17/00234 , A61B17/12013
摘要： An implantable prosthesis is provided for repairing or augmenting anatomical weaknesses or defects, and is particularly suitable for the repair of soft tissue and muscle wall openings. The prosthesis is configured to promote enhanced tissue ingrowth thereto, while limiting the incidence of post-operative adhesions between the fabric and tissue or organs. The prosthesis may include a layer of fabric that is constructed and arranged to allow tissue ingrowth and is susceptible to the formation of adhesions for tissue and organs. One or more barriers may be provided on selected portions of the fabric to inhibit the formation of adhesions with tissues and organs. The prosthesis may have an opening that is adapted to receive the esophagus or other tube-like structure, or other projection, that passes through an opening in or projects from a tissue, muscle or organ wall requiring repair and/or augmentation. The prosthesis may be configured for use in hiatal hernia repair and/or treatment of GERD. A method is also provided for the treatment of GERD.

3. 发明申请

US20110118851A1 PROSTHETIC REPAIR FABRIC WITH EROSION RESISTANT EDGE 审中-公开
标题翻译：防腐修复面料
公开(公告)号：US20110118851A1
公开(公告)日：2011-05-19
申请号：US13010594
申请日：2011-01-20
申请人： Stephen N. Eldridge , Roger E. Darois , Michael J. Lee , Valerie L. Vadurro
发明人： Stephen N. Eldridge , Roger E. Darois , Michael J. Lee , Valerie L. Vadurro
IPC分类号： A61F2/02 , A61B17/00
CPC分类号： A61F2/0063 , A61F2/0077
摘要： An implantable prosthesis is provided for repairing or augmenting anatomical weaknesses or defects, and is particularly suitable for the repair of soft tissue and muscle wall openings. The prosthesis may include a repair fabric that is constructed and arranged to allow tissue ingrowth and is susceptible to erosion into and the formation of adhesions with tissue and organs. One or more regions of the prosthesis may be configured to inhibit erosion into and/or the formation of adhesions with tissue and organs. The prosthesis may include an erosion resistant edge to buffer an edge of the fabric from the adjacent tissue or organs. The erosion resistant edge may be provided along an opening that is adapted to receive a tube-like structure, such as the esophagus.
摘要翻译：为可修复或增加解剖缺陷或缺陷提供可植入假体，并且特别适用于修复软组织和肌肉壁开口。假体可以包括构造和布置成允许组织向内生长并且易于侵蚀和与组织和器官形成粘连的修复织物。假体的一个或多个区域可以被配置为抑制对组织和器官的粘连的侵蚀和/或形成粘连。假体可以包括抗侵蚀边缘以从邻近的组织或器官缓冲织物的边缘。抗侵蚀边缘可以沿着适于接收管状结构（例如食道）的开口设置。

4. 发明授权

US07011688B2 Prosthetic repair fabric 有权
公开(公告)号：US07011688B2
公开(公告)日：2006-03-14
申请号：US10143743
申请日：2002-05-10
申请人： Paul vonRyll Gryska , Stephen N. Eldridge , Roger E. Darois , Michael J. Lee , Valerie Vadurro
发明人： Paul vonRyll Gryska , Stephen N. Eldridge , Roger E. Darois , Michael J. Lee , Valerie Vadurro
IPC分类号： A61F2/02
CPC分类号： A61F2/0063 , A61F2/0077
摘要： An implantable prosthesis is provided for repairing or augmenting anatomical weaknesses or defects, and is particularly suitable for the repair of soft tissue and muscle wall openings. The prosthesis includes a repair fabric with a generally triangular-shaped body and two tails extending outward from the base of the triangular body. The tails may be rounded to provide the repair fabric with a generally heart-shaped configuration. An opening is provided along the base of the body and between the two tails for receiving a tube-like structure, such as the esophagus. The prosthesis may include a layer of fabric that is constructed and arranged to allow tissue ingrowth and is susceptible to erosion into and the formation of adhesions with tissue and organs. One or more regions of the prosthesis may be configured to inhibit erosion into and/or the formation of adhesions with tissue and organs. The prosthesis may include an edge barrier that is attached to the tails and overlies a portion of the opening. A portion of the edge barrier may be folded into the opening to isolate the tube-like structure from an edge of the opening.

5. 发明授权

US06736854B2 Prosthetic repair fabric with erosion resistant edge 有权
标题翻译：假面修补面料具有抗侵蚀边缘
公开(公告)号：US06736854B2
公开(公告)日：2004-05-18
申请号：US10143746
申请日：2002-05-10
申请人： Valerie Vadurro , Roger E. Darois , Stephen N. Eldridge , Michael J. Lee
发明人： Valerie Vadurro , Roger E. Darois , Stephen N. Eldridge , Michael J. Lee
IPC分类号： A61F202
CPC分类号： A61F2/0063
摘要： An implantable prosthesis is provided for repairing or augmenting anatomical weaknesses or defects, and is particularly suitable for the repair of soft tissue and muscle wall openings. The prosthesis may include a layer of fabric that is constructed and arranged to allow tissue ingrowth and is susceptible to erosion into and the formation of adhesions with tissue and organs. The prosthesis is configured to inhibit edge erosion of the prosthesis into surrounding tissue and organs. The prosthesis may include an erosion resistant edge to buffer an edge of the fabric from the adjacent tissue or organs. The erosion resistant edge may be provided along an opening that is adapted to receive a tube-like structure, such as the esophagus.
摘要翻译：为可修复或增加解剖缺陷或缺陷提供可植入假体，并且特别适用于修复软组织和肌肉壁开口。假体可以包括构造和布置以允许组织向内生长并且易于侵蚀和与组织和器官形成粘连的织物层。假体构造成抑制假体边缘侵蚀到周围组织和器官中。假体可以包括抗侵蚀边缘以从邻近的组织或器官缓冲织物的边缘。抗侵蚀边缘可以沿着适于接收管状结构（例如食道）的开口设置。

6. 发明授权

US06790213B2 Implantable prosthesis 有权
标题翻译：植入假体
公开(公告)号：US06790213B2
公开(公告)日：2004-09-14
申请号：US10040936
申请日：2002-01-07
申请人： Dennis Cherok , Stephen N. Eldridge , Roger E. Darois , Patrick J. Devlin , Matthew R. Fenton , Steven Palmer Ford , Philip A. Tessier
发明人： Dennis Cherok , Stephen N. Eldridge , Roger E. Darois , Patrick J. Devlin , Matthew R. Fenton , Steven Palmer Ford , Philip A. Tessier
IPC分类号： A61B1708
CPC分类号： A61F2/0063
摘要： An implantable prosthesis for an anatomical defect, such as a tissue or muscle defect, that promotes tissue or muscle growth into the prosthesis and subsequently strengthens the area of the defect. At least one pocket and preferably two concentric pockets may be provided to aid with manipulating the prosthesis. Where two pockets are used, a barrier or partition exists between the pockets and the outer pocket allows manipulation of the outer periphery. The incidence of postoperative adhesions between a portion of the prosthesis and tissue, muscle or organs may be minimized with the use of a barrier layer. Reinforcing members may be attached to portions of the prosthesis to aid in positioning and deployment in the area of desired coverage without rendering the prosthesis unduly difficult to implant or uncomfortable for the patient. Typically, two concentric members are employed. Further, the prosthesis is constructed to allow it to be provisionally held in place at desired locations by openings in the pockets that allow access for a stapler or sewing device.
摘要翻译：用于解剖缺损的可植入假体，例如组织或肌肉缺损，其促进组织或肌肉生长进入假体并随后加强缺损区域。可以提供至少一个口袋并且优选地两个同心的口袋来帮助操作假体。在使用两个口袋的情况下，在凹穴之间存在隔离物或分隔件，并且外口袋允许操纵外周边。可以使用阻挡层将假体和组织，肌肉或器官的一部分之间的术后粘连的发生率最小化。加强构件可以附接到假体的部分，以帮助定位和展开在期望的覆盖区域，而不会使假体过度难以植入或不适合患者。通常使用两个同心的构件。此外，假体构造成允许其通过允许缝合器或缝合装置进入的口袋中的开口临时保持在所需位置。

7. 发明申请

US20130296897A1 SELF ADHERING IMPLANTABLE MESH PROSTHESIS WITH REDUCED INSERTION PROFILE 审中-公开
标题翻译：自助式可插入网络具有减少的插入轮廓
公开(公告)号：US20130296897A1
公开(公告)日：2013-11-07
申请号：US13460938
申请日：2012-05-01
申请人： Anthony Trupiano , Stephen N. Eldridge , Donald Anthony Coelho, JR. , Kevin J. Ranucci , Roger E. Darois
发明人： Anthony Trupiano , Stephen N. Eldridge , Donald Anthony Coelho, JR. , Kevin J. Ranucci , Roger E. Darois
IPC分类号： A61B17/03
CPC分类号： A61F2/0063 , A61F2/0077 , A61F2002/0068 , A61F2230/0091
摘要： The present invention is an implantable adhesive mesh prosthesis for reinforcing and/or repairing a defect in tissue that is easy to roll into a small diameter cylinder or other low-profile shape for passing through a trocar, incision, or other surgical instrument. More specifically, the adhesive may be applied to the mesh material in a pattern that leaves a significant portion of the surface area of the mesh material free of adhesive. In one embodiment, the adhesive is applied only near the outer perimeter of the mesh product. In another embodiment, the adhesive is applied in spots over all or a portion the surface of the mesh product. In yet another embodiment, the adhesive is applied in parallel lines on the surface of the mesh product and the mesh may be rolled up around an axis parallel to the lines of adhesive.
摘要翻译：本发明是一种用于加强和/或修复组织中的缺陷的可植入粘合剂网络假体，该缺损易于卷入小直径的圆柱体或其它小轮廓形状以穿过套管针，切口或其它手术器械。更具体地，粘合剂可以以离开网状材料的表面积的大部分没有粘合剂的图案施加到网状材料。在一个实施例中，粘合剂仅施加在网状产品的外周附近。在另一个实施方案中，将粘合剂施加在网状产品的全部或部分表面上的斑点上。在另一个实施方案中，粘合剂以网格产品的表面上的平行线施加，并且网可以围绕平行于粘合剂线的轴卷起。

8. 发明授权

US10159552B2 Self adhering implantable mesh prosthesis with reduced insertion profile 有权
公开(公告)号：US10159552B2
公开(公告)日：2018-12-25
申请号：US13460938
申请日：2012-05-01
申请人： Anthony Trupiano , Stephen N. Eldridge , Donald Anthony Coelho, Jr. , Kevin J. Ranucci , Roger E. Darois
发明人： Anthony Trupiano , Stephen N. Eldridge , Donald Anthony Coelho, Jr. , Kevin J. Ranucci , Roger E. Darois
IPC分类号： A61F2/00
摘要： The present invention is an implantable adhesive mesh prosthesis for reinforcing and/or repairing a defect in tissue that is easy to roll into a small diameter cylinder or other low-profile shape for passing through a trocar, incision, or other surgical instrument. More specifically, the adhesive may be applied to the mesh material in a pattern that leaves a significant portion of the surface area of the mesh material free of adhesive. In one embodiment, the adhesive is applied only near the outer perimeter of the mesh product. In another embodiment, the adhesive is applied in spots over all or a portion the surface of the mesh product. In yet another embodiment, the adhesive is applied in parallel lines on the surface of the mesh product and the mesh may be rolled up around an axis parallel to the lines of adhesive.

9. 发明授权

US06258124B1 Prosthetic repair fabric 有权
标题翻译：假肢修复面料
公开(公告)号：US06258124B1
公开(公告)日：2001-07-10
申请号：US09309071
申请日：1999-05-10
申请人： Roger E. Darois , Stephen N. Eldridge , Dennis Cherok , Ronald L. Greene
发明人： Roger E. Darois , Stephen N. Eldridge , Dennis Cherok , Ronald L. Greene
IPC分类号： A61F208
CPC分类号： A61F2/0063
摘要： A prosthetic repair fabric and method for repairing an inguinal hernia in the inguinal canal. The prosthesis including a layer of mesh fabric that is susceptible to the formations of adhesions with sensitive tissue and organs, and a barrier layer that inhibits the formation of adhesions with sensitive tissue and organs. The mesh fabric including a medial section and a lateral section that are configured to be positioned adjacent the medial corner and the lateral end of the inguinal canal, respectively, when the prosthesis is placed in the inguinal canal to repair the defect. The barrier layer is positioned on the mesh fabric to inhibit the formation of adhesions between the spermatic cord and the mesh fabric. At least a portion of the lateral section of the mesh fabric is free of the barrier layer on both of its sides to promote enhanced tissue ingrowth therein. The barrier layer may include at least one flap that is to be folded through the mesh fabric to isolate the spermatic cord from internal edges of the fabric when the spermatic cord is routed through the prothesis.
摘要翻译：用于修复腹股沟内腹股沟疝修补修复织物和方法。该假体包括易于与敏感组织和器官的粘连形成的网状织物层，以及抑制与敏感组织和器官形成粘连的阻挡层。所述网状织物包括中间部分和横向部分，所述中间部分和横向部分被配置为当所述假体被放置在腹股沟管中以修复所述缺陷时分别邻近所述腹股沟的内侧角和所述腹股沟的横向端。阻挡层定位在网状织物上以抑制精索和网状织物之间的粘连的形成。网状织物的横截面的至少一部分在其两侧都没有阻挡层，以促进其中的增强的组织向内生长。阻挡层可以包括至少一个折叠通过网状织物的舌片，以在精索穿过假体时将精索与织物的内边缘隔离。

10. 发明授权

US07824420B2 Implantable prosthesis 有权
标题翻译：植入假体
公开(公告)号：US07824420B2
公开(公告)日：2010-11-02
申请号：US10853823
申请日：2004-05-26
申请人： Stephen N. Eldridge , Roger Darois
发明人： Stephen N. Eldridge , Roger Darois
IPC分类号： A61B17/08 , A61F2/02
CPC分类号： A61F2/0063
摘要： An implantable prosthesis for an anatomical defect, such as a tissue or muscle defect, that promotes tissue or muscle growth into the prosthesis and subsequently strengthens the area of the defect. At least one pocket and preferably two concentric pockets may be provided to aid with manipulating the prosthesis. Where two pockets are used, a barrier or partition exists between the pockets and the outer pocket allows manipulation of the outer periphery. The incidence of postoperative adhesions between a portion of the prosthesis and tissue, muscle or organs may be minimized with the use of a barrier layer. Reinforcing members may be attached to portions of the prosthesis to aid in positioning and deployment in the area of desired coverage without rendering the prosthesis unduly difficult to implant or uncomfortable for the patient. Typically, two concentric members are employed. Further, the prosthesis is constructed to allow it to be provisionally held in place at desired locations by openings in the pockets that allow access for a stapler or sewing device.
摘要翻译：用于解剖缺损的可植入假体，例如组织或肌肉缺损，其促进组织或肌肉生长进入假体并随后加强缺损区域。可以提供至少一个口袋并且优选地两个同心的口袋来帮助操作假体。在使用两个口袋的情况下，在凹穴之间存在隔离物或分隔件，并且外口袋允许操纵外周边。可以使用阻挡层将假体和组织，肌肉或器官的一部分之间的术后粘连的发生率最小化。加强构件可以附接到假体的部分，以帮助定位和展开在期望的覆盖区域，而不会使假体过度难以植入或不适合患者。通常使用两个同心的构件。此外，假体构造成允许其通过允许缝合器或缝合装置进入的口袋中的开口临时保持在所需位置。

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