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1. 发明申请

US20080221458A1 Catheter and method for diagnosis and treatment of diseased vessels 审中-公开
标题翻译：用于诊断和治疗患病血管的导管和方法
公开(公告)号：US20080221458A1
公开(公告)日：2008-09-11
申请号：US12152612
申请日：2008-05-15
申请人： Robert W. Scott , Steven J. Rychnovsky , Ian M. Leitch , Jeffrey A. Vasek , John A. Franco
发明人： Robert W. Scott , Steven J. Rychnovsky , Ian M. Leitch , Jeffrey A. Vasek , John A. Franco
IPC分类号： A61B6/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B18/245 , A61B2017/00057 , A61B2017/22067 , A61N5/0601 , A61N5/062
摘要： The present invention provides a catheter for detecting and treating diseased tissue in a blood vessel or other hollow body organ. The catheter comprises an elongated tubular catheter shaft having a distal end comprising a light transmission zone. A first fiber lumen in the catheter shaft contains a diagnostic optical fiber having a distal end terminating within the light transmission zone for emitting and receiving light through the light transmission zone. A diagnostic subassembly at the proximal end and in communication with the diagnostic optical fiber processes diagnostic light for use in connection with a diagnostic method for detecting diseased tissue. A second fiber lumen can be provided in the catheter shaft for containing a treatment optical fiber for delivering treatment light from a light source at the proximal end of the catheter shaft to the light transmission zone. The treatment optical fiber has a distal end terminating within the light transmission zone for emitting light for treatment of the diseased tissue. An occlusion balloon is positioned on the distal end of the catheter shaft adjacent to the light transmission zone and in fluid communication with an inflation lumen. One or more infusion ports formed on or near the light transmission zone and in fluid communication with an infusion lumen deliver infusion fluid to the hollow body organ.
摘要翻译：本发明提供一种用于检测和治疗血管或其他中空体器官中的病变组织的导管。导管包括细长的管状导管轴，其具有包括透光区的远端。导管轴中的第一纤维腔包含诊断光纤，其具有端部在光透射区内的远端，用于通过透光区发射和接收光。诊断子组件在近端处并与诊断光纤通信处理诊断光，用于与用于检测患病组织的诊断方法结合使用。可以在导管轴上设置第二纤维腔，用于容纳用于将处理光从导管轴的近端处的光源输送到光透射区的处理光纤。处理光纤具有终端在光透射区内的远端，用于发射用于治疗患病组织的光。闭塞气囊位于导管轴的远端与光透射区相邻并与膨胀腔流体连通。形成在透光区上或其附近并与输注腔流体连通的一个或多个输注端口将输注流体输送到中空身体器官。

2. 发明授权

US07396354B2 Light delivery catheter 失效
标题翻译：光输送导管
公开(公告)号：US07396354B2
公开(公告)日：2008-07-08
申请号：US10634664
申请日：2003-08-05
申请人： Steven J. Rychnovsky , John A. Franco , Jeffrey A. Vasek , C. T. Lo Blong , John S. Hill
发明人： Steven J. Rychnovsky , John A. Franco , Jeffrey A. Vasek , C. T. Lo Blong , John S. Hill
IPC分类号： A61B18/18
CPC分类号： A61N5/0601 , A61B18/245 , A61B2017/00057 , A61B2017/22067 , A61N5/062
摘要： The present invention provides improved light delivery catheters for use in therapeutic methods, such as PDT, that require illumination of target tissue within a blood vessel or other hollow body organ. An improved catheter includes an optical fiber that transmits light from a light source at the proximal end of the catheter shaft to a light treatment zone. An occlusion balloon on the distal end of the catheter shaft adjacent to the light treatment zone receives fluid via an inflation lumen in the catheter shaft. An infusion lumen connects with a plurality of infusion ports at the light treatment zone to deliver infusion fluid to the hollow body organ so that blood can be flushed from the region between the light treatment zone and target tissue.
摘要翻译：本发明提供了用于治疗方法（例如PDT）的改进的光输送导管，其需要照射血管或其它中空体器官内的靶组织。改进的导管包括将光从导管轴的近端处的光源透射到光处理区的光纤。邻近光处理区的导管轴的远端上的闭塞气囊通过导管轴中的充气腔容纳流体。输注腔与光处理区域处的多个输注端口连接以将输注流体输送到中空身体器官，使得可以从光处理区域和靶组织之间的区域冲洗血液。

3. 发明授权

US06415823B1 Catheter tip insert 有权
标题翻译：导管尖端插入
公开(公告)号：US06415823B1
公开(公告)日：2002-07-09
申请号：US09302605
申请日：1999-04-30
申请人： Jeffrey A. Vasek , Lori Cone Speckman
发明人： Jeffrey A. Vasek , Lori Cone Speckman
IPC分类号： B65O5900
CPC分类号： A61M27/006 , A61M2025/0078 , A61M2025/09116
摘要： An insert is disclosed that is placed in the slit in a slit tipped catheter during storage of the catheter. This insert prevents opposite of the slit from contacting and forming bonds that tend to close the slit. When the catheter is to be used, the insert is removed and the catheter is used in its intended way.
摘要翻译：公开了一种插入物，其在导管的储存期间放置在狭缝尖端的导管中的狭缝中。该插入物防止狭缝相对的接触和形成倾向于闭合狭缝的粘合。当使用导管时，移除插入物，并以其预期的方式使用导管。

4. 发明授权

US06971390B1 Catheter connection and repair system 有权
标题翻译：导管连接和修理系统
公开(公告)号：US06971390B1
公开(公告)日：2005-12-06
申请号：US10071378
申请日：2002-02-05
申请人： Jeffrey A. Vasek , John A. Zawacki
发明人： Jeffrey A. Vasek , John A. Zawacki
IPC分类号： A61M25/00 , A61M39/02 , A61M39/10 , A61M39/12 , F16L33/00 , F16L33/22 , F16M16/00
CPC分类号： A61M39/12 , A61M25/0097 , A61M39/0208 , A61M39/1011 , A61M2039/1033 , F16L33/223 , Y10T403/10
摘要： A system for effecting fluid-tight coupling and mechanical joinder between a medical device and a catheter tube. An elongated catheter connection stem attached to the medical device is received in the lumen of the catheter. A catheter securement collar is advanced proximally along the exterior of the catheter and connection stem inside the catheter into the assembled condition of the connection system, passing a locking ring on the interior of the securement collar over an enlargement on the distal end of the connection stem. Maximum catheter compression occurs at the locking ring, while a void internal of the catheter system is filled with an enlarged securement lip of catheter material. Distal of maximum catheter wall compression, the catheter traverses a tortuous path between the locking ring and the enlargement, around the shoulder of the enlargement, and along the adjacent surface of the enlargement.
摘要翻译：用于在医疗装置和导管管之间进行流体密封联接和机械连接的系统。附接到医疗装置的细长的导管连接杆容纳在导管的内腔中。导管固定套环沿着导管的外部和导管内部的连接杆向近侧前进到连接系统的组装状态，将锁定环通过固定环的内部在连接杆的远端上的放大图上。在锁定环处发生最大的导管压缩，而导管系统内部的空隙填充有放大的导管材料的固定唇。最大导管壁压缩的远端，导管穿过锁定环与扩大部之间的曲折路径，围绕放大的肩部，并沿着放大的相邻表面。

5. 发明授权

US08226632B2 Connection methods 有权
标题翻译：连接方式
公开(公告)号：US08226632B2
公开(公告)日：2012-07-24
申请号：US11295741
申请日：2005-12-05
申请人： John A. Zawacki , Jeffrey A. Vasek
发明人： John A. Zawacki , Jeffrey A. Vasek
IPC分类号： A61M25/16 , F16L33/00 , F16L47/00 , F16L49/00
CPC分类号： A61M39/12 , A61M25/0097 , A61M39/0208 , A61M39/1011 , A61M2039/1033 , F16L33/223 , Y10T403/10
摘要： Methods of coupling a catheter to a stem are disclosed. In some embodiments, a stem extends longitudinally between a proximal end and a distal end, and the stem can include at least one enlargement positioned between the proximal end and the distal end. In some embodiments, a catheter can be positioned over the at least one enlargement and over a region of the stem that is proximal to the at least one enlargement. In further embodiments, a collar can be mated to the stem.
摘要翻译：公开了将导管连接到杆的方法。在一些实施例中，杆在近端和远端之间纵向延伸，并且杆可以包括位于近端和远端之间的至少一个放大部。在一些实施例中，可以将导管定位在所述至少一个放大体上方，并且位于所述茎的靠近所述至少一个放大部分的区域上方。在另外的实施例中，套环可以配合到杆上。

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