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1. 发明申请

US20130072915A1 System and Method for Moving the Focal Point of a Laser Beam 审中-公开
标题翻译：用于移动激光束焦点的系统和方法
公开(公告)号：US20130072915A1
公开(公告)日：2013-03-21
申请号：US13405052
申请日：2012-02-24
申请人： Robert Edward Grant , David Haydn Mordaunt , Kristian Hohla , Gwillem Mosedale
发明人： Robert Edward Grant , David Haydn Mordaunt , Kristian Hohla , Gwillem Mosedale
IPC分类号： A61F9/011 , A61B18/20
CPC分类号： A61F9/00825 , A61B5/0066
摘要： A system and method are provided wherein an operational characteristic of a laser beam is identified. A predetermined ophthalmic reference datum is also identified. The identified laser beam characteristic is then used in its relationship with the reference datum for guidance and control of the laser beam's focal point. In operation, the laser beam's focal point is moved through eye tissue while minimizing any deviations of the operational characteristic of the laser beam from the reference datum.
摘要翻译：提供了一种识别激光束的操作特性的系统和方法。还识别了预定的眼科参考基准。然后将所识别的激光束特性用于与参考基准的关系，用于引导和控制激光束的焦点。在操作中，激光束的焦点通过眼睛组织移动，同时最小化激光束的操作特性与参考基准的任何偏差。

2. 发明申请

US20130103010A1 System and Method for Laser Ablation on a Surgical Surface 审中-公开
标题翻译：手术表面激光消融的系统和方法
公开(公告)号：US20130103010A1
公开(公告)日：2013-04-25
申请号：US13405069
申请日：2012-02-24
申请人： Robert Edward Grant , David Haydn Mordaunt , Kristian Hohla , Gwillem Mosedale
发明人： Robert Edward Grant , David Haydn Mordaunt , Kristian Hohla , Gwillem Mosedale
IPC分类号： A61F9/01 , A61F9/011 , A61B18/20
CPC分类号： A61F9/00825 , A61F2009/00851 , A61F2009/00863 , A61F2009/00865 , A61F2009/0087 , A61F2009/00872 , A61F2009/00874
摘要： A system and method for performing Laser Induced Optical Breakdown (LIOB) on a target tissue includes a detector for imaging the interface surface between the target tissue and a base tissue. Also included is a laser unit for generating a laser beam, and for focusing the laser beam to a focal point. A computer is provided for controlling movement of the focal point. Specifically, this control is accomplished to maintain the focal point in the target tissue, but beyond a predetermined distance from the interface surface. For the present invention, the predetermined distance is established by considerations of laser beam geometry, which are applied in the context of images that are created of the interface surface.
摘要翻译：用于在目标组织上执行激光诱导光学分解（LIOB）的系统和方法包括用于对目标组织和基础组织之间的界面进行成像的检测器。还包括用于产生激光束并用于将激光束聚焦到焦点的激光单元。提供了一种用于控制焦点的移动的计算机。具体地说，该控制是为了保持目标组织中的焦点，但是超出距离界面表面的预定距离。对于本发明，通过考虑激光束几何来确定预定距离，激光束几何被应用在由界面表面创建的图像的上下文中。

3. 发明授权

US10716706B2 System and method for performing lens fragmentation 有权
公开(公告)号：US10716706B2
公开(公告)日：2020-07-21
申请号：US13436352
申请日：2012-03-30
申请人： Frieder Loesel , Jochen Kandulla , Friedrich Moritz , Gwillem Mosedale , Holger Schlueter , Roland Toennies , Gerhard Youssefi , David Haydn Mordaunt
发明人： Frieder Loesel , Jochen Kandulla , Friedrich Moritz , Gwillem Mosedale , Holger Schlueter , Roland Toennies , Gerhard Youssefi , David Haydn Mordaunt
IPC分类号： A61F9/008
摘要： A system and method are provided for fragmenting a crystalline lens, to facilitate its removal from the lens bag during an ophthalmic laser surgery. First, a predetermined pattern is used to make Laser Induced Optical Breakdown (LIOB) cuts that section the lens into asymmetrical, operational segments. At least one operational segment is then selected and softened with a plurality of compact LIOB cuts. Once softened, the selected segment is aspirated. The remaining operational segments are then subsequently removed. During a procedure, an imaging unit can monitor movements of the lens bag to ensure proper placement of the LIOB cuts on the lens.

4. 发明申请

US20120259320A1 System and Method for Performing Lens Fragmentation 审中-公开
标题翻译：执行镜头碎片的系统和方法
公开(公告)号：US20120259320A1
公开(公告)日：2012-10-11
申请号：US13436352
申请日：2012-03-30
申请人： Frieder Loesel , Jochen Kandulla , Friedrich Moritz , Gwillem Mosedale , Holger Schlueter , Roland Toennies , Gerhard Youssefi , David Haydn Mordaunt
发明人： Frieder Loesel , Jochen Kandulla , Friedrich Moritz , Gwillem Mosedale , Holger Schlueter , Roland Toennies , Gerhard Youssefi , David Haydn Mordaunt
IPC分类号： A61B18/20
CPC分类号： A61F9/00825 , A61F2009/00851 , A61F2009/0087 , A61F2009/00887
摘要： A system and method are provided for fragmenting a crystalline lens, to facilitate its removal from the lens bag during an ophthalmic laser surgery. First, a predetermined pattern is used to make Laser Induced Optical Breakdown (LIOB) cuts that section the lens into asymmetrical, operational segments. At least one operational segment is then selected and softened with a plurality of compact LIOB cuts. Once softened, the selected segment is aspirated. The remaining operational segments are then subsequently removed. During a procedure, an imaging unit can monitor movements of the lens bag to ensure proper placement of the LIOB cuts on the lens.
摘要翻译：提供了一种用于使晶状体碎裂的系统和方法，以便于在眼科激光手术期间从晶状体袋移除晶状体。首先，使用预定的图案来制造将透镜划分为不对称的，可操作的部分的激光诱导光学分解（LIOB）切割。然后，利用多个紧凑的LIOB切割来选择和软化至少一个操作段。一旦软化，所选择的部分被吸出。其余的操作段随后被移除。在一个过程中，成像单元可以监控透镜袋的运动，以确保LIOB切口在透镜上的正确放置。

5. 发明授权

US08807752B2 System and method with refractive corrections for controlled placement of a laser beam's focal point 有权
$System and method with refractive corrections for controlled placement of a laser beam's focal point$
标题翻译：具有折射校正的系统和方法，用于受控放置激光束的焦点
公开(公告)号：US08807752B2
公开(公告)日：2014-08-19
申请号：US13415679
申请日：2012-03-08
申请人： Frieder Loesel , Kristian Hohla , Gwillem Mosedale
发明人： Frieder Loesel , Kristian Hohla , Gwillem Mosedale
IPC分类号： A61B3/14
CPC分类号： A61F9/00825 , A61F9/00834
摘要： A methodology is provided for correcting the placement of a laser beam's focal point. Specifically, this correction is done to compensate for displacements of the focal point that may be caused when implant material (e.g. an Intraocular Lens (IOL)) is positioned on the optical path of the laser beam. The methodology of the present invention then determines a deviation of the laser beam's refracted target position (uncompensated) from its intended target position. A calculation of the deviation includes considerations of the laser beam's wavelength and refractive/diffractive characteristics introduced by the implant material. This deviation is then added to the refracted target position to make the refracted target position coincide with the intended target position of the focal point. The laser beam will then focus to its intended target position.
摘要翻译：提供了一种校正激光束焦点位置的方法。具体地，进行这种校正以补偿当植入材料（例如人造眼镜（IOL））位于激光束的光路上时可能引起的焦点位移。然后，本发明的方法确定激光束的折射目标位置（未补偿）与其预期目标位置的偏差。偏差的计算包括激光束的波长和由植入材料引入的折射/衍射特性的考虑。然后将该偏差加到折射目标位置，以使折射的目标位置与焦点的预期目标位置一致。然后激光束将聚焦到其预期的目标位置。

6. 发明申请

US20130235341A1 System and Method for Controlled Reduction of Opacities in an Eye 有权
标题翻译：控制减少眼睛不透明度的系统和方法
公开(公告)号：US20130235341A1
公开(公告)日：2013-09-12
申请号：US13415679
申请日：2012-03-08
申请人： Frieder Loesel , Kristian Hohla , Gwillem Mosedale
发明人： Frieder Loesel , Kristian Hohla , Gwillem Mosedale
IPC分类号： A61B3/14 , A61B3/10
CPC分类号： A61F9/00825 , A61F9/00834
摘要： A methodology is provided for correcting the placement of a laser beam's focal point. Specifically, this correction is done to compensate for displacements of the focal point that may be caused when implant material (e.g. an Intraocular Lens (IOL)) is positioned on the optical path of the laser beam. The methodology of the present invention then determines a deviation of the laser beam's refracted target position (uncompensated) from its intended target position. A calculation of the deviation includes considerations of the laser beam's wavelength and refractive/diffractive characteristics introduced by the implant material. This deviation is then added to the refracted target position to make the refracted target position coincide with the intended target position of the focal point. The laser beam will then focus to its intended target position.
摘要翻译：提供了一种校正激光束焦点位置的方法。具体地，进行这种校正以补偿当植入材料（例如人造眼镜（IOL））位于激光束的光路上时可能引起的焦点位移。然后，本发明的方法确定激光束的折射目标位置（未补偿）与其预期目标位置的偏差。偏差的计算包括激光束的波长和由植入材料引入的折射/衍射特性的考虑。然后将该偏差加到折射目标位置，以使折射的目标位置与焦点的预期目标位置一致。然后激光束将聚焦到其预期的目标位置。

7. 发明申请

US20140257257A1 SYSTEMS AND METHODS FOR TREATING TARGET TISSUE IN THE VITREOUS CAVITY 审中-公开
标题翻译：用于治疗病灶中的目标组织的系统和方法
公开(公告)号：US20140257257A1
公开(公告)日：2014-09-11
申请号：US13793844
申请日：2013-03-11
申请人： Robert Edward Grant , Gwillem Mosedale , David Mordaunt
发明人： Robert Edward Grant , Gwillem Mosedale , David Mordaunt
IPC分类号： A61F9/007 , A61F9/008
CPC分类号： A61F9/00802 , A61F9/00825 , A61F2009/00851 , A61F2009/00874
摘要： A system and its method for treating targeted tissue in the vitreous cavity of an eye include a laser unit for generating a laser beam and a detector for creating an image of the targeted tissue. The system also includes a computer which defines a focal spot path for emulsifying the targeted tissue. A comparator that is connected with the computer then controls the laser unit to move the focal spot of the laser beam. This focal spot movement is accomplished to treat the targeted tissue, while minimizing deviations of the focal spot from the defined focal spot path.
摘要翻译：用于治疗眼睛玻璃体腔内的靶组织的系统及其方法包括用于产生激光束的激光单元和用于产生目标组织图像的检测器。该系统还包括限定用于乳化目标组织的焦点路径的计算机。与计算机连接的比较器然后控制激光单元移动激光束的焦斑。完成该焦斑运动以对目标组织进行处理，同时最小化焦斑与定义的焦斑路径的偏差。

8. 发明申请

US20140135752A1 System and Method for Configuring Fragmentation Segments of a Crystalline Lens for a Lensectomy 审中-公开
标题翻译：用于配置镜片切割的晶状体镜片的碎片段的系统和方法
公开(公告)号：US20140135752A1
公开(公告)日：2014-05-15
申请号：US13837112
申请日：2013-03-15
申请人： Vladislav Duma , Toh Seng Goh , Brian D. McCary , Gwillem Mosedale
发明人： Vladislav Duma , Toh Seng Goh , Brian D. McCary , Gwillem Mosedale
IPC分类号： A61F9/008 , A61F9/007
CPC分类号： A61F9/00825 , A61F9/00736 , A61F2009/0087 , A61F2009/00887
摘要： A system and method are provided for fragmenting a crystalline lens inside an operational volume in the lens. A reference axis that is based on the crystalline lens is established, and various pluralities of parallel planes are defined relative to the reference axis. A pulsed laser beam is then used to cut tissue in selected planes, to thereby fragment the lens by performing Laser Induced Optical Breakdown (LIOB) on the tissue. In accordance with the present invention each plurality of parallel planes is characterized by a particular inclination angle “φ” relative to the reference axis, a particular azimuthal angle “θ” relative to the reference axis, and an intersection angle “ψ” relative to each other.
摘要翻译：提供了一种系统和方法，用于在晶状体的操作体积内分散晶状体。建立了基于晶状体的基准轴，并且相对于参考轴限定了多个平行平面。然后使用脉冲激光束来切割选定平面中的组织，从而通过在组织上执行激光诱导光学破坏（LIOB）来分裂透镜。根据本发明，每个多个平行平面的特征在于相对于参考轴具有特定的倾斜角“＆phgr”;特定的方位角“＆amp;”;相对于参考轴，并且相交角“ψ”相对对彼此。

9. 发明授权

US09629750B2 Surgical laser unit with variable modes of operation 有权
公开(公告)号：US09629750B2
公开(公告)日：2017-04-25
申请号：US13450180
申请日：2012-04-18
申请人： Florian Dambacher , Markus Hailmann , Frieder Loesel , Gwillem Mosedale
发明人： Florian Dambacher , Markus Hailmann , Frieder Loesel , Gwillem Mosedale
IPC分类号： A61F9/008 , A61F9/009
CPC分类号： A61F9/00825 , A61F9/009 , A61F2009/00897
摘要： A comprehensive multi-mode system for performing ophthalmic laser surgery on selected tissue inside an eye includes a laser unit for generating and focusing a laser beam to perform Laser Induced Optical Breakdown (LIOB) at a focal point in selected tissue. Also included is a selector for defining an operational mode according to characteristics of the tissue to be altered by LIOB. In combination, the operational mode specifies value ranges for configuration parameters for a pulsed femtosecond laser beam, establishes a base reference datum in the eye, and identifies a scanning procedure for the focal point of the laser beam to customize the system for a particular surgical procedure. A computer that is connected to the laser unit is responsive to the selector for implementing the operational mode.

10. 发明申请

US20130281991A1 Surgical Laser Unit with Variable Modes of Operation 有权
标题翻译：具有可变运行模式的手术激光单元
公开(公告)号：US20130281991A1
公开(公告)日：2013-10-24
申请号：US13450180
申请日：2012-04-18
申请人： Gwillem Mosedale , Floran Dambacher , Markus Hailmann , Frieder Loesel
发明人： Gwillem Mosedale , Floran Dambacher , Markus Hailmann , Frieder Loesel
IPC分类号： A61F9/011
CPC分类号： A61F9/00825 , A61F9/009 , A61F2009/00897
摘要： A comprehensive multi-mode system for performing ophthalmic laser surgery on selected tissue inside an eye includes a laser unit for generating and focusing a laser beam to perform Laser Induced Optical Breakdown (LIOB) at a focal point in selected tissue. Also included is a selector for defining an operational mode according to characteristics of the tissue to be altered by LIOB. In combination, the operational mode specifies value ranges for configuration parameters for a pulsed femtosecond laser beam, establishes a base reference datum in the eye, and identifies a scanning procedure for the focal point of the laser beam to customize the system for a particular surgical procedure. A computer that is connected to the laser unit is responsive to the selector for implementing the operational mode.
摘要翻译：用于在眼睛内的选定组织上进行眼科激光手术的全面的多模式系统包括用于在所选组织的焦点处产生和聚焦激光束以执行激光诱导光学细分（LIOB）的激光单元。还包括用于根据要由LIOB改变的组织的特征定义操作模式的选择器。结合起来，操作模式指定脉冲飞秒激光束的配置参数的值范围，在眼睛中建立基准参考基准，并识别激光束的焦点的扫描过程，以定制特定外科手术的系统。连接到激光单元的计算机响应于选择器来实现操作模式。

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