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1. 发明申请

US20100209897A1 Intraoral behavior monitoring and aversion devices and methods 审中-公开
标题翻译：口内行为监测与厌恶手段及方法
公开(公告)号：US20100209897A1
公开(公告)日：2010-08-19
申请号：US12590073
申请日：2009-11-02
申请人： David Scott Utley , Michael Berman , Peter T. Keith , Robert E. Atkinson , Jack Denton Utley, JR.
发明人： David Scott Utley , Michael Berman , Peter T. Keith , Robert E. Atkinson , Jack Denton Utley, JR.
IPC分类号： G09B19/00
CPC分类号： A24F47/00
摘要： An intraoral behavior monitoring and aversion device to assist a user in quitting an undesirable behavior such as tobacco smoking, tobacco chewing, use of snuff, illicit drug use, excessive alcohol consumption, excessive food consumption, and/or other undesirable activity facilitated via the mouth. The aversion device may be wholly or partially configured to be disposed in the user's mouth, for example. The aversion device may include a detector and a output device, wherein the detector is configured to detect a parameter indicative of the user engaging in the habit or undesirable activity. If (and only if) the detector detects such a parameter, the output device may, optionally, deliver a negative stimulus to the user, thus providing negative feedback and creating an incentive for the user to limit if not eliminate the undesirable activity. The device may be configured to store and/or relay data representing sensed conditions in the mouth.
摘要翻译：口腔内行为监测和厌恶装置，以帮助用户戒除不期望的行为，例如吸烟，烟草咀嚼，使用鼻烟，非法药物使用，过度饮酒，食物过量消耗和/或通过口促进的其他不良活动。例如，厌恶装置可以被全部或部分地配置为设置在使用者的口中。厌恶装置可以包括检测器和输出装置，其中检测器被配置为检测指示用户参与习惯或不期望的活动的参数。如果（且仅当）检测器检测到这样的参数，输出设备可以可选地向用户传递负激励，从而提供负反馈并且为用户创造激励以限制如果不消除不期望的活动。该装置可以被配置为存储和/或中继表示嘴中感测到的状况的数据。

2. 发明申请

US20110015714A1 Lead stabilization devices and methods 审中-公开
标题翻译：铅稳定装置和方法
公开(公告)号：US20110015714A1
公开(公告)日：2011-01-20
申请号：US12807683
申请日：2010-09-10
申请人： Robert E. Atkinson , Peter T. Keith , Michael Berman
发明人： Robert E. Atkinson , Peter T. Keith , Michael Berman
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： Devices and methods for stabilizing a lead in a cardiac vein.
摘要翻译：用于稳定心脏静脉中铅的装置和方法。

3. 发明授权

US07797053B2 Lead stabilization devices and methods 失效
标题翻译：铅稳定装置和方法
公开(公告)号：US07797053B2
公开(公告)日：2010-09-14
申请号：US11139894
申请日：2005-05-27
申请人： Robert E. Atkinson , Peter T. Keith , Michael Berman
发明人： Robert E. Atkinson , Peter T. Keith , Michael Berman
IPC分类号： A61N1/05
CPC分类号： A61F2/86 , A61F2/95 , A61F2220/0008 , A61F2230/005 , A61F2230/0076 , A61N1/057
摘要： Devices and methods for stabilizing an electrical lead in a cardiac vein of a heart using a tether and a stent anchor. The stent anchor may include a proximal eccentric apex such that the distal electrode of the lead lies against and establishes electrical contact with tissue of the heart.
摘要翻译：用于使用系绳和支架锚稳定心脏心脏静脉中的电引线的装置和方法。支架锚固件可以包括近端偏心顶点，使得引线的远端电极抵靠并与心脏的组织形成电接触。

4. 发明授权

US08034023B2 Emboli protection devices and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US08034023B2
公开(公告)日：2011-10-11
申请号：US12695827
申请日：2010-01-28
申请人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
发明人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
IPC分类号： A61M29/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a lesion within a blood vessel, includes providing an evacuation sheath assembly having a multi-lumen tube with proximal and distal ends, first and second lumens therebetween, and at least one sealing surface mounted on the distal end of the multi-lumen tube. The evacuation sheath assembly is advanced to a region of interest within a blood vessel. The sealing surface is deployed upstream of the region of interest to occlude antegrade flow adjacent to the lesion to be treated. A dilation catheter is advanced through the multi-lumen tube such that the dilation balloon is positioned across the lesion and the lesion is dilated. Suction is applied to induce retrograde blood flow to carry dislodged embolic material into a lumen of the evacuation sheath assembly.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。一种治疗血管内的病变的方法，包括提供具有多腔管的抽吸鞘组件，其具有近端和远端，其间具有第一和第二腔，并且至少一个密封表面安装在多腔管的远端上，流明管。疏散鞘组件前进到血管内的感兴趣区域。密封表面部署在感兴趣区域的上游，以阻塞邻近待治疗的病变的顺行流。扩张导管通过多腔管推进，使得扩张气囊跨越病变并且病变扩张。吸引用于诱导逆行血流，将移出的栓塞物质运送到排泄鞘组件的内腔中。

5. 发明授权

US07959603B2 Emboli protection devices and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US07959603B2
公开(公告)日：2011-06-14
申请号：US11824451
申请日：2007-06-29
申请人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
发明人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
IPC分类号： A61M29/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a blood vessel, includes providing an elongate member having proximal and distal ends, a lumen therebetween, the distal end having a braided sheath expandable between a reduced and expanded diameter, and a fluid-tight covering. The elongate member is advanced into a blood vessel that supplies blood to the heart. The braided sheath is expanded to engage the endoluminal surface of the blood vessel and stop antegrade flow.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。一种治疗血管的方法，包括提供具有近端和远端的细长构件，其间的腔，所述远端具有可在缩径和扩张直径之间扩张的编织护套和流体密封的覆盖物。细长构件前进到向心脏供应血液的血管。编织的鞘被扩张以接合血管的内腔表面并停止顺行的流动。

6. 发明授权

US08430845B2 Emboli protection devices and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US08430845B2
公开(公告)日：2013-04-30
申请号：US12786305
申请日：2010-05-24
申请人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
发明人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
IPC分类号： A61M29/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An embolic protection system and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The embolic protection system includes a guide catheter, a multi-lumen tube having a sealing surface on the distal end and an interventional device. A method of treating a blood vessel includes providing a guide catheter and a multi-lumen elongate member having proximal and distal ends, evacuation and inflation lumens extending therebetween and a sealing surface on the distal end. The elongate member is advanced through the guide catheter into a blood vessel that supplies blood to the heart proximal a lesion. The sealing surface is expanded to engage the endoluminal surface of the blood vessel and stop antegrade flow. An interventional device is advanced through the evacuation lumen to treat the lesion.
摘要翻译：提供了栓塞保护系统和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。栓塞保护系统包括引导导管，具有远端密封表面的多腔管和介入装置。治疗血管的方法包括提供导向导管和具有近端和远端的多腔细长构件，在其间延伸的抽空和充气腔以及远端上的密封表面。细长构件通过引导导管前进到血管，该血管将血液提供给病灶附近的心脏。密封表面被膨胀以与血管的内腔表面接合并停止顺行流动。介入装置通过疏散腔前进以治疗病变。

7. 发明授权

US07867216B2 Emboli protection device and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US07867216B2
公开(公告)日：2011-01-11
申请号：US11337126
申请日：2006-01-19
申请人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
发明人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
IPC分类号： A61M31/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a lesion within a blood vessel, e.g., a coronary artery, includes advancing a sheath into the blood vessel, the sheath having a lumen extending to a port at a distal end of the sheath and further having an occlusive member within a distal region of the sheath. The occlusive member is then positioned within the blood vessel proximal to the lesion. Subsequently, the occlusive member is deployed, thereby stopping antegrade flow across the lesion. A contrast agent can then be infused through a port in the sheath. A dilation balloon is then advanced across the lesion. Suction is then applied to the lumen to induce retrograde flow across the lesion after dilating the lesion.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。治疗血管（例如冠状动脉）内的病变的方法包括使鞘进入血管，护套具有延伸到护套远端端口处的内腔，并且还具有闭塞构件护套的远端区域。然后将闭塞性构件定位在靠近病变的血管内。随后，闭塞成员被部署，从而阻止穿过病变的顺行流动。然后可以通过护套中的端口注入造影剂。然后将扩张气囊推进穿过病变。然后在扩张病变之后，将吸引应用于管腔以诱导穿过病变的逆行流。

8. 发明申请

US20100234855A1 EMBOLI PROTECTION DEVICES AND RELATED METHODS OF USE 有权
标题翻译： EMBOLI保护装置及相关使用方法
公开(公告)号：US20100234855A1
公开(公告)日：2010-09-16
申请号：US12786305
申请日：2010-05-24
申请人： DENNIS W. WAHR , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
发明人： DENNIS W. WAHR , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
IPC分类号： A61B17/22 , A61M29/02
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An embolic protection system and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The embolic protection system includes a guide catheter, a multi-lumen tube having a sealing surface on the distal end and an interventional device. A method of treating a blood vessel includes providing a guide catheter and a multi-lumen elongate member having proximal and distal ends, evacuation and inflation lumens extending therebetween and a sealing surface on the distal end. The elongate member is advanced through the guide catheter into a blood vessel that supplies blood to the heart proximal a lesion. The sealing surface is expanded to engage the endoluminal surface of the blood vessel and stop antegrade flow. An interventional device is advanced through the evacuation lumen to treat the lesion.
摘要翻译：提供了栓塞保护系统和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。栓塞保护系统包括引导导管，具有远端密封表面的多腔管和介入装置。治疗血管的方法包括提供导向导管和具有近端和远端的多腔细长构件，在其间延伸的抽空和充气腔以及远端上的密封表面。细长构件通过引导导管前进到血管，该血管将血液提供给病灶附近的心脏。密封表面被膨胀以与血管的内腔表面接合并停止顺行流动。介入装置通过疏散腔前进以治疗病变。

9. 发明申请

US20100130999A1 EMBOLI PROTECTION DEVICES AND RELATED METHODS OF USE 有权
标题翻译： EMBOLI保护装置及相关使用方法
公开(公告)号：US20100130999A1
公开(公告)日：2010-05-27
申请号：US12695827
申请日：2010-01-28
申请人： DENNIS W. WAHR , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
发明人： DENNIS W. WAHR , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
IPC分类号： A61M29/02
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a lesion within a blood vessel, includes providing an evacuation sheath assembly having a multi-lumen tube with proximal and distal ends, first and second lumens therebetween, and at least one sealing surface mounted on the distal end of the multi-lumen tube. The evacuation sheath assembly is advanced to a region of interest within a blood vessel. The sealing surface is deployed upstream of the region of interest to occlude antegrade flow adjacent to the lesion to be treated. A dilation catheter is advanced through the multi-lumen tube such that the dilation balloon is positioned across the lesion and the lesion is dilated. Suction is applied to induce retrograde blood flow to carry dislodged embolic material into a lumen of the evacuation sheath assembly.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。一种治疗血管内的病变的方法，包括提供具有多腔管的抽吸鞘组件，其具有近端和远端，其间具有第一和第二腔，并且至少一个密封表面安装在多腔管的远端上，流明管。疏散鞘组件前进到血管内的感兴趣区域。密封表面部署在感兴趣区域的上游，以阻塞邻近待治疗的病变的顺行流。扩张导管通过多腔管推进，使得扩张气囊跨越病变并且病变扩张。吸引用于诱导逆行血流，将移出的栓塞物质运送到排泄鞘组件的内腔中。

10. 发明授权

US07422579B2 Emboli protection devices and related methods of use 有权
标题翻译： Emboli保护装置及相关使用方法
公开(公告)号：US07422579B2
公开(公告)日：2008-09-09
申请号：US09845162
申请日：2001-05-01
申请人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
发明人： Dennis W. Wahr , Thomas V. Ressemann , Peter T. Keith , David J. Blaeser , Michael Berman
IPC分类号： A61M31/00
CPC分类号： A61B17/12136 , A61B17/12045 , A61B17/12109 , A61B90/39 , A61B2017/12127 , A61B2017/22067 , A61F2/95
摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Prior to advancing a device across a stenosis to be treated, normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped. While blood flow is stopped, the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly.
摘要翻译：提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。抽真空组件包括限定具有近端和远端的抽空腔的细长管。近侧密封表面设置在管的近端部分上，并被构造成与引导导管的内腔形成密封。远端密封表面设置在管的远端部分上并构造成与血管形成密封。使用排气鞘组件治疗血管的方法包括通过引导导管将排空鞘组件推进到血管中。在将装置推进通过待治疗的狭窄之前，停止在狭窄附近的血管中的正常顺行血流。当血流停止时，狭窄处理。在血管内引起逆行血流，以便在处理进入抽真空鞘组件期间将栓塞物移走。

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