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1. 发明申请

US20060210610A1 Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use 有权
公开(公告)号：US20060210610A1
公开(公告)日：2006-09-21
申请号：US11371167
申请日：2006-03-07
申请人： Robert Davidson , Gary Kehoe
发明人： Robert Davidson , Gary Kehoe
IPC分类号： A61K47/00
CPC分类号： A61K9/0056 , A61K9/7007 , A61K31/451 , A61K31/4545 , A61K31/4985 , A61K31/519 , A61K31/53 , A61K31/573 , A61K47/10 , A61K47/36 , A61K47/38
摘要： Methods for modulating dissolution, bioavailability, bioequivalence and drug delivery profile of thin film drug delivery systems, controlled-release thin film dosage formats, and methods for their manufacture and use are disclosed.

2. 发明申请

US20070134280A1 Thixotropic ingestible formulation to treat sore throat 审中-公开
标题翻译：触痛性摄入用来治疗喉咙痛的配方
公开(公告)号：US20070134280A1
公开(公告)日：2007-06-14
申请号：US11704628
申请日：2007-02-09
申请人： Stephen Roman , Gary Kehoe
发明人： Stephen Roman , Gary Kehoe
IPC分类号： A61K9/00 , A61K31/715
CPC分类号： A61K9/06 , A61K9/0053 , A61K9/0095 , A61K31/715
摘要： A thixotropic formulation includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water.
摘要翻译：触变制剂包括从藻类提取的高分子量，触变性，凝胶形成的天然存在的多糖，并且包含重复的硫酸化和非硫酸化的半乳糖和3,6脱水半乳糖（3,6 -AG）单元，并且包括水。

3. 发明申请

US20070135377A1 Thixotropic anti-viral formulation 审中-公开
标题翻译：触变性抗病毒制剂
公开(公告)号：US20070135377A1
公开(公告)日：2007-06-14
申请号：US11704566
申请日：2007-02-09
申请人： Stephen Roman , Gary Kehoe
发明人： Stephen Roman , Gary Kehoe
IPC分类号： A61K31/715
CPC分类号： A61K9/0043 , A61K9/0053 , A61K31/715
摘要： A thixotropic anti-viral formulation includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water.
摘要翻译：触变性抗病毒制剂包括从藻类提取的高分子量，触变性，凝胶形成的天然存在的多糖，并且包含重复的硫酸化和非硫酸化的半乳糖和3,6脱水半乳糖（3,6-AG）单元，并且包括水。

4. 发明授权

US5626892A Method for production of multi-flavored and multi-colored chewing gum 失效
标题翻译：生产多味和多色口香糖的方法
公开(公告)号：US5626892A
公开(公告)日：1997-05-06
申请号：US158067
申请日：1993-11-24
申请人： Gary Kehoe , Thomas J. Carroll , Donald L. Mihalich
发明人： Gary Kehoe , Thomas J. Carroll , Donald L. Mihalich
IPC分类号： A23G4/00 , A23G4/02 , A23G4/04 , A23G4/20 , A23G3/30
CPC分类号： A23G4/20 , A23G4/02 , A23G4/043
摘要： Multi-veined chewing gum is produced by injecting a plurality of different liquid flavor/dye compositions into a substantially homogeneous gum base composition or into a laminated or coextruded gum composition. The injection may be performed while the gum composition is being conveyed in one or more extruder head barrels, the injection being at a plurality of radial and/or circumferential positions in the barrel. In embodiments of the invention substantially straight longitudinal veins of color are then partially mixed to partially displace the colored veins in a direction transverse to the direction of extrusion so as to create veined, multi-colored patterns substantially throughout a cross section of the product in a manner so that the multi-colored patterns in the cross-section differ along the length of the extrudate. The extrudate is cut to obtain gum pieces having different veins of injected liquid additives which provide a swirled or marbleized pattern in the opposing cut ends. The injected liquid additive compositions may include flavors, dyes, lakes, high intensity sweeteners, therapeutic agents, breath freshening agents, and mixtures thereof. Surface veins may also be produced by injection of liquid colorant/flavorant compositions onto the substantially homogeneous gum base composition as it passes through the extrusion head barrel. The surface veins may be disrupted or displaced independently of the interior veins using a rotatable sleeve or gum rope twisting device.
摘要翻译：通过将多种不同的液体调味剂/染料组合物注入基本上均匀的胶基组合物中或通过将多种口香糖组合物注入层压或共挤出的口香糖组合物中来制备多脉冲口香糖。注射可以在口香糖组合物在一个或多个挤出机头桶中输送的同时进行，注射在筒中的多个径向和/或周向位置。在本发明的实施例中，然后将基本上直的纵向静脉色素部分地混合以在垂直于挤出方向的方向上部分地移动着色静脉，从而基本上遍及产品的横截面中产生脉冲的多色图案使得横截面中的多色图案沿挤出物的长度不同。将挤出物切割成具有不同静脉注射液体添加剂的胶片，其在相对的切割端提供旋转或大理石化图案。注射的液体添加剂组合物可以包括调味剂，染料，湖泊，高强度甜味剂，治疗剂，呼吸清新剂及其混合物。表面静脉也可以通过在基本均匀的胶基组合物通过挤压头筒时将液体着色剂/调味剂组合物注射到基本均匀的胶基组合物上来制备。使用可旋转的套筒或胶绳扭转装置，表面静脉可能会与内部静脉独立地破坏或移位。

5. 发明授权

US4352824A Chewing gum containing fatty or gelatinous sweetener and method 失效
标题翻译：含脂肪或凝胶状甜味剂的口香糖及方法
公开(公告)号：US4352824A
公开(公告)日：1982-10-05
申请号：US295334
申请日：1981-08-24
申请人： Wayne J. Puglia , Gary Kehoe , Frank Witzel , K. Warren Clark , Donald A. M. Mackay
发明人： Wayne J. Puglia , Gary Kehoe , Frank Witzel , K. Warren Clark , Donald A. M. Mackay
IPC分类号： A23G4/00 , A23G4/06 , A23G4/18 , A23G4/20 , A23G3/30
CPC分类号： A23G4/06 , A23G4/182 , A23G4/20
摘要： A chewing gum is provided which contains gum base and a non-aqueous solid fatty or gelatinous sweetener or flavorant, such as butter, marshmallow or caramel, solubilized in the gum base. The subject chewing gum has the appearance and mouth feel of chewing gum as opposed to candy and a delayed but prolonged sweetness or flavor impact. The chewing gum is laminated with a slab of chewing gum which will supply initial sweetness or flavor impact.A method for producing the above chewing gum is also provided.
摘要翻译：提供了一种口香糖，其包含胶基和溶解在胶基中的非水固体脂肪或凝胶状甜味剂或调味剂，例如黄油，棉花糖或焦糖。主题口香糖具有与糖果相反的口香糖的外观和口感，并且具有延迟但延长的甜味或风味影响。口香糖与一种口香糖片层压，这将提供初始的甜度或风味影响。还提供了一种生产上述口香糖的方法。

6. 发明授权

US4317837A Tobacco-flavored chewing gum 失效
标题翻译：烟味香口香糖
公开(公告)号：US4317837A
公开(公告)日：1982-03-02
申请号：US210190
申请日：1980-11-25
申请人： Gary Kehoe , Wayne J. Puglia , Frank Witzel , Dominick R. Friello , Donald A. M. Mackay
发明人： Gary Kehoe , Wayne J. Puglia , Frank Witzel , Dominick R. Friello , Donald A. M. Mackay
IPC分类号： A23G4/00 , A23G4/06 , A23G4/08 , A23G4/18 , A23G3/30
CPC分类号： A23G4/06 , A23G4/064 , A23G4/068 , A23G4/08 , A23G4/182
摘要： A tobacco-flavored chewing gum is provided which does not decrease in viscosity upon chewing inasmuch as it is preferably essentially free of water-solubles, and includes gum base containing high levels of inert fillers, such as calcium carbonate or talc in amounts of at least about 50% by weight, softeners, such as lecithin, synthetic non-caloric sweeteners, such as aspartame, saccharin or cyclamates, and tobacco flavors and/or natural tobacco. The chewing gum includes at least about 10% air voids entrapped in the gum base matrix which, upon chewing, become filled with moisture causing a dramatic increase in cud volume.
摘要翻译：提供了一种烟草香味的口香糖，其咀嚼时的粘度不降低，因为其优选基本上不含水溶性物质，并且包括至少含有高含量的惰性填料如碳酸钙或滑石的胶基约50重量％的软化剂，例如卵磷脂，合成的非热量甜味剂，例如阿斯巴甜，糖精或环磷酰胺，以及烟草香料和/或天然烟草。所述口香糖包括至少约10％的包封在胶基基质中的空气空隙，其在咀嚼时变得充满水分，导致嚼体积的显着增加。

7. 发明申请

US20070087036A1 Edible film for transmucosal delivery of nutritional supplements 审中-公开
标题翻译：用于经粘膜递送营养补品的食用薄膜
公开(公告)号：US20070087036A1
公开(公告)日：2007-04-19
申请号：US11417676
申请日：2006-05-03
申请人： Maurice Durschlag , Gary Kehoe
发明人： Maurice Durschlag , Gary Kehoe
IPC分类号： A61K47/00
CPC分类号： A61K9/006 , A23L33/00 , A23L33/10 , A23L33/15 , A23L33/155 , A23L33/16 , A23L33/175 , A23P20/12 , A23P20/20
摘要： In one embodiment of the present invention a composition is provided comprising a film layer wherein the film layer rapidly dissolves in an oral cavity and a coating comprising a powder matrix, wherein the coating is applied to at least one side of the film layer and wherein the powder matrix comprises a nutritional supplement, an adhesive, a bulking agent, a flow agent, and a sweetener.
摘要翻译：在本发明的一个实施方案中，提供了一种组合物，其包括膜层，其中膜层快速溶解在口腔中，以及包含粉末基质的涂层，其中将涂层施加到膜层的至少一侧，并且其中粉末基质包含营养补充剂，粘合剂，填充剂，流动剂和甜味剂。

8. 发明申请

US20060292102A1 Thixotropic personal lubricant 审中-公开
标题翻译：触变个人润滑剂
公开(公告)号：US20060292102A1
公开(公告)日：2006-12-28
申请号：US11501609
申请日：2006-08-09
申请人： Stephen Roman , Gary Kehoe
发明人： Stephen Roman , Gary Kehoe
IPC分类号： A61K8/73
CPC分类号： A61Q19/00 , A61K8/042 , A61K8/73 , A61K9/0034 , A61K31/737 , A61K47/36 , A61Q15/00
摘要： A thixotropic personal lubricant includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water.
摘要翻译：触变个人润滑剂包括从藻类提取的高分子量，触变性，凝胶形成的天然存在的多糖，并且包含重复的硫酸化和非硫酸化的半乳糖和3,6脱水半乳糖（3,6-AG）单元，并且包括水。

9. 发明申请

US20060127340A1 Thixotropic personal lubricant 审中-公开
公开(公告)号：US20060127340A1
公开(公告)日：2006-06-15
申请号：US11210293
申请日：2005-08-24
申请人： Stephen Roman , Gary Kehoe
发明人： Stephen Roman , Gary Kehoe
IPC分类号： A61K8/73 , A61K36/02
CPC分类号： A61Q19/00 , A61K8/73 , A61K36/02 , A61Q15/00
摘要： A thixotropic personal lubricant includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water.

10. 发明授权

US5324530A Apparatus and method for making extruded chewing gum 失效
标题翻译：制造挤出口香糖的装置和方法
公开(公告)号：US5324530A
公开(公告)日：1994-06-28
申请号：US66677
申请日：1993-05-24
申请人： Gary Kehoe , John Zimmerman , Thomas Carroll , Michael Diehl
发明人： Gary Kehoe , John Zimmerman , Thomas Carroll , Michael Diehl
IPC分类号： A23G3/02 , A23G4/00 , A23G4/04 , A23G4/18 , A23L1/00 , A23P1/12 , B29B7/48 , A23G7/00 , A23P1/00 , B29B7/00
CPC分类号： A23G4/182 , A23G3/0294 , A23G4/04 , A23P30/25 , B29B7/481 , B29C47/6037 , B29C47/6056 , B29C47/6087
摘要： Material such as chewing gum is treated to reduce its density by working it and feeding it through a twin-screw corotating extruder configured to provide flow at first and second longitudinal rates, pulling in a plane normal to the axis of flow, and further working and homogenization.
摘要翻译：处理诸如口香糖的材料以通过加工它来减少其密度，并将其通过双螺杆共旋转挤出机进行送料，所述双螺杆共旋转挤出机配置成在第一和第二纵向速率下提供流动，在垂直于流动轴线的平面中拉动，并进一步加工和均质化

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