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1. 发明申请

US20070264505A1 Surfaces that resist the adsorption of biological species 有权
公开(公告)号：US20070264505A1
公开(公告)日：2007-11-15
申请号：US11825998
申请日：2007-07-09
申请人： Robert Chapman , Emanuele Ostuni , Michael Liang , Lin Yan , George Whitesides
发明人： Robert Chapman , Emanuele Ostuni , Michael Liang , Lin Yan , George Whitesides
IPC分类号： B32B9/04
CPC分类号： B82Y30/00 , A61L15/42 , A61L27/34 , A61L27/50 , A61L31/10 , B32B27/06 , B82Y5/00 , Y10T428/26 , Y10T428/265 , Y10T428/268 , Y10T428/269 , Y10T428/31504 , Y10T428/31678 , Y10T428/31681 , Y10T428/31725 , Y10T428/31855
摘要： The present invention provides articles resistant to the adsorption of proteins, cells and bacteria. The articles can either have a chemical chain bonded thereon where the chemical chain can comprise a terminal group free of a hydrogen bond donor or where a hydrogen bond donor is sufficiently buried such that an exposed surface of the article including the chemical chain is free of a hydrogen bond donor. The chemical chain, or plurality of chemical chains, can comprise a monolayer such as a self-assembled monolayer (SAM) which can be homogeneous (one type of SAM) or mixed, i.e. or more different types of SAMs. Other more specific examples of chemical chains are provided. The plurality of chemical chains can comprise a polymer such as a polyamine. In many aspects, the plurality of chemical chains is sufficiently free of cross-linking or branching. The present invention also provides an article capable of specific binding of a desired biomolecule while preventing non-specific binding of biomolecules.

2. 植物专利

USPP28353P3 Viola plant named ‘Sweetheart’ 有权
公开(公告)号：USPP28353P3
公开(公告)日：2017-08-29
申请号：US14998505
申请日：2016-01-14
申请人： Robert Chapman
发明人： Robert Chapman
IPC分类号： A01H5/02
摘要： A new cultivar of Viola plant named ‘Sweetheart’ that is distinguishable by compact basally branching habit, medium to large single blooms which are predominantly cream-yellow in color, fringed with lavender-blue margins, and flowers which are heavily pleasantly fragrant. ‘Sweetheart’ is hardy in USDA Zone 5 and blooms from early spring through fall.

3. 发明授权

US07674798B2 Oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone 有权
公开(公告)号：US07674798B2
公开(公告)日：2010-03-09
申请号：US11653530
申请日：2007-01-16
申请人： Robert Chapman , Lonn S. Rider , Qi Hong , Donald Kyle , Robert Kupper
发明人： Robert Chapman , Lonn S. Rider , Qi Hong , Donald Kyle , Robert Kupper
IPC分类号： A61K31/485 , C07D489/08
CPC分类号： C07D489/08 , A61K9/14 , A61K9/20 , A61K9/2095 , A61K9/48 , A61K9/4833 , A61K31/485 , C07D489/02 , C07D489/04
摘要： In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.

4. 发明授权

US08198219B2 Method for producing solid materials on the basis of synthetic polymers and/or biopolymers and use thereof 失效
标题翻译：基于合成聚合物和/或生物聚合物生产固体材料的方法及其用途
公开(公告)号：US08198219B2
公开(公告)日：2012-06-12
申请号：US12918686
申请日：2009-02-16
申请人： Simon Champ , Robert Chapman
发明人： Simon Champ , Robert Chapman
IPC分类号： C09K8/90 , C09K8/68 , C09K8/588
CPC分类号： C08J3/21 , C08B1/003 , C08J3/005 , C08J3/091 , C08K5/0008 , C08K5/0016 , C08L1/02 , C08L5/00 , C08L5/04 , C08L5/08 , C08L5/16 , C08L23/0869 , C08L89/00 , C08L89/04 , C09D101/02 , C09K8/80 , D21H17/24 , D21H17/33 , C08L2666/26
摘要： The use of solid materials based on synthetic polymers and/or biopolymers (A) in natural gas and mineral oil extraction technology. The solid materials are produced by solubilizing at least one synthetic polymer and/or biopolymer (A), or at least one synthetic polymer and/or biopolymer (A) and at least one additive (B), in at least one substantially anhydrous chaotropic liquid (C). The solution or dispersion (AC) or (ABC) is contacted with a liquid (D1) which is miscible with the chaotropic liquid (C), but in which at least the synthetic polymer and/or the biopolymer (A) are substantially insoluble, resulting in a phase (E). The chaotropic liquid (C) is removed from phase (E) to result in a gel (G), which is impregnated with a liquid (D2). The two liquids (D1) and (D2) are removed from the gel (G) by evaporating, producing a solid material based on synthetic polymer and/or biopolymer (A).
摘要翻译：在天然气和矿物油萃取技术中使用基于合成聚合物和/或生物聚合物（A）的固体材料。固体材料通过将至少一种合成聚合物和/或生物聚合物（A）或至少一种合成聚合物和/或生物聚合物（A）和至少一种添加剂（B）溶解在至少一种基本上无水的离液液体（C）。溶液或分散体（AC）或（ABC）与液体（D1）接触，液体（D1）可与离液液体（C）混溶，但至少合成聚合物和/或生物聚合物（A）基本上不溶，导致阶段（E）。从相（E）中除去离液混合液（C）以产生用液体（D2）浸渍的凝胶（G）。通过蒸发将两种液体（D1）和（D2）从凝胶（G）中除去，产生基于合成聚合物和/或生物聚合物（A）的固体材料。

5. 发明申请

US20100191787A1 Sequential Multiplier 审中-公开
标题翻译：顺序乘数
公开(公告)号：US20100191787A1
公开(公告)日：2010-07-29
申请号：US12362257
申请日：2009-01-29
申请人： Robert Chapman
发明人： Robert Chapman
IPC分类号： G06F7/52 , G06F7/00
CPC分类号： G06F7/527
摘要： A sequential multiplier for multiplying a binary multiplier and a binary multiplicand to produce a final product. A first logic circuit generates a control signal based on the multiplier. A second logic circuit generates a partial product based on the control signal and the multiplicand. A full adder generates a partial sum and a partial carry in each of a sequence of cycles. In the first cycle the partial sum and the partial carry are both initialized to zero. In each said cycle the partial sum, the partial carry, and the partial product are added to generate a new partial sum and a new partial carry. After a last cycle, the partial sum is the final product.
摘要翻译：用于乘以二进制乘法器和二进制被乘数以产生最终乘积的顺序乘法器。第一逻辑电路基于乘法器产生控制信号。第二逻辑电路基于控制信号和被乘数产生部分乘积。全加器在循环的序列中产生部分和和部分进位。在第一个周期中，部分和和部分进位都被初始化为零。在每个所述周期中，加上部分和，部分进位和部分乘积以产生新的部分和和新的部分进位。在最后一个周期之后，部分和是最终产品。

6. 发明授权

US07674800B2 Oxycodone hydrochloride having less than 25 PPM 14-hydroxycodeinone 有权
标题翻译：具有小于25PPM的14-羟可待因酮的羟考酮盐酸盐
公开(公告)号：US07674800B2
公开(公告)日：2010-03-09
申请号：US11729741
申请日：2007-03-29
申请人： Robert Chapman , Lonn S. Rider , Qi Hong , Donald Kyle , Robert Kupper
发明人： Robert Chapman , Lonn S. Rider , Qi Hong , Donald Kyle , Robert Kupper
IPC分类号： A61K31/485 , C07D489/08
CPC分类号： C07D489/08 , A61K9/14 , A61K9/20 , A61K9/2095 , A61K9/48 , A61K9/4833 , A61K31/485 , C07D489/02 , C07D489/04
摘要： In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
摘要翻译：在某些实施方案中，本发明涉及制备具有小于25ppm的14-羟可待因酮的盐酸羟考酮组合物的方法。

7. 发明申请

US20050222188A1 Process for preparing oxycodone hydrochloride having less than 25 PPM 14-hydroxycodeinone 有权
标题翻译：制备具有小于25PPM的14-羟可待因酮的羟考酮盐酸盐的方法
公开(公告)号：US20050222188A1
公开(公告)日：2005-10-06
申请号：US11093626
申请日：2005-03-30
申请人： Robert Chapman , Lonn Rider , Qi Hong , Donald Kyle , Robert Kupper
发明人： Robert Chapman , Lonn Rider , Qi Hong , Donald Kyle , Robert Kupper
IPC分类号： A61K31/485 , C07D489/00 , C07D489/08
CPC分类号： C07D489/08 , A61K9/14 , A61K9/20 , A61K9/2095 , A61K9/48 , A61K9/4833 , A61K31/485 , C07D489/02 , C07D489/04
摘要： In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
摘要翻译：在某些实施方案中，本发明涉及制备具有小于25ppm的14-羟可待因酮的盐酸羟考酮组合物的方法。

8. 发明授权

US09619004B1 Reducing system power consumption due to USB host controllers 有权
公开(公告)号：US09619004B1
公开(公告)日：2017-04-11
申请号：US11613845
申请日：2006-12-20
申请人： John Berendsen , Robert Chapman
发明人： John Berendsen , Robert Chapman
IPC分类号： G06F1/32
CPC分类号： G06F1/325 , G06F1/3212 , G06F1/3253 , G06F1/329
摘要： Circuits, methods, and apparatus that reduce the power consumed by data transfers initiated by a USB host controller. Peripheral devices on a USB network are accessed with a reduced frequency in order to save power dissipated by a CPU and other circuits when reading data needed by the host controller. Instead of possibly accessing devices each frame, peripheral devices are accessed during some frames, and not accessed during others. A USB host controller may have two or more modes, such as a low power mode and a regular mode. In the low power mode, USB devices are accessed during fewer than all frames, in the regular mode, USB devices are possibly accessed each frame. Mode selection may depend on whether battery power is used.

9. 植物专利

US20160212906P1 Viola plant named 'Amy' 有权
标题翻译：中提琴植物名为“艾米”
公开(公告)号：US20160212906P1
公开(公告)日：2016-07-21
申请号：US14998506
申请日：2016-01-14
申请人： Robert Chapman
发明人： Robert Chapman
IPC分类号： A01H5/00
摘要： A new cultivar of Viola plant named ‘Amy’ that is distinguishable by compact basally branching habit, medium to large violet colored flowers with dark ray markings and striking bright orange eyes, and flowers which are heavily pleasantly fragrant. ‘Amy’ is hardy in USDA Zone 5 and blooms from early spring through fall.
摘要翻译：一种名为“艾米”的新品种，由紧密的基底分枝习性，中等到大紫罗兰色的鲜花与深色光线标记和醒目的明亮的橙色眼睛，以及浓郁的香味鲜花组成。美国农业部5号“艾米”在早春，秋天开花。

10. 发明授权

US09073933B2 Oxycodone hydrochloride having less than 25 PPM 14-hydroxycodeinone 有权
标题翻译：具有小于25PPM的14-羟可待因酮的羟考酮盐酸盐
公开(公告)号：US09073933B2
公开(公告)日：2015-07-07
申请号：US13366755
申请日：2012-02-06
申请人： Robert Chapman , Lonn S. Rider , Qi Hong , Donald Kyle , Robert Kupper
发明人： Robert Chapman , Lonn S. Rider , Qi Hong , Donald Kyle , Robert Kupper
IPC分类号： A61K31/485 , C07D489/08 , C07D489/02
CPC分类号： C07D489/08 , A61K9/14 , A61K9/20 , A61K9/2095 , A61K9/48 , A61K9/4833 , A61K31/485 , C07D489/02 , C07D489/04
摘要： In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
摘要翻译：在某些实施方案中，本发明涉及制备具有小于25ppm的14-羟可待因酮的盐酸羟考酮组合物的方法。

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