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1. 发明申请

US20130195335A1 AUTOMATIC QUANTIFICATION OF MITRAL VALVE DYNAMICS WITH REAL-TIME 3D ULTRASOUND 有权
标题翻译：用实时三维超声波自动定量麻醉动力学
公开(公告)号：US20130195335A1
公开(公告)日：2013-08-01
申请号：US13580833
申请日：2011-02-25
申请人： Robert C. Gorman , Alison Pouch , Joseph H. Gorman, III , Chandra Sehgal , Paul A. Yushkevich , Benjamin Jackson
发明人： Robert C. Gorman , Alison Pouch , Joseph H. Gorman, III , Chandra Sehgal , Paul A. Yushkevich , Benjamin Jackson
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T7/12 , G06T7/174 , G06T2207/10076 , G06T2207/20128 , G06T2207/30048
摘要： A series of rt-3DE images of the mitral valve are quantitatively analyzed so as to enable, for example, prediction of the degree of recurrent ischemic mitral regurgitation (IMR) and comprehensive assessments of leaflet tethering and “tenting” for the entire mitral valve. In accordance with the method, first, the rt-3DE images are registered with symmetric diffeomorphism to obtain information about how the mitral valve deforms over time. Second, the mitral valve is segmented with the level sets or other known segmentation method at each time point in the cardiac cycle with minimal user interaction. Third, the information about mitral valve structure is reduced into a 3D medial model, a compact representation of shape. In other words, a volumetric segmentation of the mitral valve is condensed to a form that is amenable to clinically relevant morphometry.
摘要翻译：定量分析二尖瓣的一系列rt-3DE图像，以便例如预测复发性缺血性二尖瓣反流程度（IMR）的程度，并综合评估整个二尖瓣的小叶束缚和“起搏”。根据该方法，首先，rt-3DE图像以对称不同形态记录，以获得关于二尖瓣随时间变化的信息。其次，在心脏周期的每个时间点，二尖瓣与水平集或其他已知的分割方法分段，最小的用户交互作用。第三，关于二尖瓣结构的信息被简化为3D中间模型，形状的紧凑表示。换句话说，二尖瓣的体积分割被冷凝成适合临床相关形态测定的形式。

2. 发明授权

US09129392B2 Automatic quantification of mitral valve dynamics with real-time 3D ultrasound 有权
标题翻译：用实时三维超声自动量化二尖瓣动态
公开(公告)号：US09129392B2
公开(公告)日：2015-09-08
申请号：US13580833
申请日：2011-02-25
申请人： Robert C. Gorman , Alison Pouch , Joseph H. Gorman, III , Chandra Sehgal , Paul A. Yushkevich , Benjamin Jackson
发明人： Robert C. Gorman , Alison Pouch , Joseph H. Gorman, III , Chandra Sehgal , Paul A. Yushkevich , Benjamin Jackson
IPC分类号： G06K9/00 , G06T7/00
CPC分类号： G06T7/0012 , G06T7/12 , G06T7/174 , G06T2207/10076 , G06T2207/20128 , G06T2207/30048
摘要： A series of rt-3DE images of the mitral valve are quantitatively analyzed so as to enable, for example, prediction of the degree of recurrent ischemic mitral regurgitation (IMR) and comprehensive assessments of leaflet tethering and “tenting” for the entire mitral valve. In accordance with the method, first, the rt-3DE images are registered with symmetric diffeomorphism to obtain information about how the mitral valve deforms over time. Second, the mitral valve is segmented with the level sets or other known segmentation method at each time point in the cardiac cycle with minimal user interaction. Third, the information about mitral valve structure is reduced into a 3D medial model, a compact representation of shape. In other words, a volumetric segmentation of the mitral valve is condensed to a form that is amenable to clinically relevant morphometry.
摘要翻译：定量分析二尖瓣的一系列rt-3DE图像，以便例如预测复发性缺血性二尖瓣反流程度（IMR）的程度，并综合评估整个二尖瓣的小叶束缚和“起搏”。根据该方法，首先，rt-3DE图像以对称不同形态记录，以获得关于二尖瓣随时间变化的信息。其次，在心脏周期的每个时间点，二尖瓣与水平集或其他已知的分割方法分段，最小的用户交互作用。第三，关于二尖瓣结构的信息被简化为3D中间模型，形状的紧凑表示。换句话说，二尖瓣的体积分割被冷凝成适合临床相关形态测定的形式。

3. 发明申请

US20130052155A1 Compositions and Methods for Treating a Disorder or Defect in Soft Tissue 审中-公开
标题翻译：治疗软组织障碍或缺陷的组合和方法
公开(公告)号：US20130052155A1
公开(公告)日：2013-02-28
申请号：US13508466
申请日：2010-11-09
申请人： Michele Marcolongo , Edward Vresilovic , Benjamin Jackson , Sumona Sarkar , Caroline Schauer
发明人： Michele Marcolongo , Edward Vresilovic , Benjamin Jackson , Sumona Sarkar , Caroline Schauer
IPC分类号： C07K17/08 , A61K31/78 , A61K38/39 , A61P19/00 , C08G63/91 , A61P9/00 , A61P19/04 , A61P27/02 , A61P25/00 , A61P19/02 , A61K31/765 , A61P17/00
CPC分类号： C08L5/08 , C08B37/003 , C08B37/0063 , C08B37/0069 , C08B37/0072 , C08B37/0075 , C08G81/00 , C08L5/00 , C08L5/10
摘要： The present invention encompasses methods and compositions for generating a biomimetic proteoglycan. The invention includes methods of treating a disease, disorder, or condition of soft tissue using a biomimetic proteoglycan.
摘要翻译：本发明包括用于产生仿生蛋白多糖的方法和组合物。本发明包括使用生物模拟蛋白多糖治疗软组织的疾病，病症或病症的方法。

4. 发明申请

US20070016303A1 Implant for spinal stabilization and its method of use 有权
标题翻译：脊柱稳定植入物及其使用方法
公开(公告)号：US20070016303A1
公开(公告)日：2007-01-18
申请号：US11448308
申请日：2006-06-06
申请人： Benjamin Jackson
发明人： Benjamin Jackson
IPC分类号： A61F2/44
CPC分类号： A61B17/7062
摘要： A generally rectangular intra-spinous spacer preferably made of bone material advantageously has a low potential for bone fusion. The spacer has depressions sized and positioned on opposite sides to receive spinal processes. The depressions reduce the amount of bone-to-spinal process contact. A fixation strap of the spacer secured either to both the superior and inferior spinous processes or to only one of the superior or inferior processes laterally maintains the implanted position of the spacer and limits either flexion and extension, just flexion, or just extension.
摘要翻译：优选由骨材料制成的大致矩形的棘突间隔离物有利地具有低的骨融合潜力。间隔物具有凹陷尺寸并定位在相对侧以接收脊柱过程。凹陷减少骨 - 脊髓过程接触的量。固定在上下棘突之间的间隔物的固定带横向地保持了间隔件的植入位置，限制了屈曲和伸展，屈曲或仅延伸。

5. 发明申请

US20080039847A1 Implant and system for stabilization of the spine 审中-公开
标题翻译：植入物和系统稳定脊柱
公开(公告)号：US20080039847A1
公开(公告)日：2008-02-14
申请号：US11890830
申请日：2007-08-08
申请人： Mark Piper , Benjamin Jackson
发明人： Mark Piper , Benjamin Jackson
IPC分类号： A61B17/58 , A61B17/56
CPC分类号： A61B17/7059
摘要： According to an aspect of the present disclosure, a spinal plating system for facilitating stabilization of the spine is provided. The spinal plating system comprises superior and inferior plate members for positioning against exterior surfaces of respective superior and inferior vertebrae and in contacting relation therewith. The superior and inferior plate members include cooperating contacting surfaces adapted to engage each other to maintain a minimum predetermined distraction distance between the superior and inferior vertebrae and to permit at least one of relative articulating movement, pivoting movement or lateral movement of the superior and inferior plate members. The spinal plating system further includes at least one fastener for mounting each of the superior and inferior plate members to the respective superior and inferior vertebrae.
摘要翻译：根据本公开的一个方面，提供了一种用于促进脊柱稳定的脊椎电镀系统。脊椎电镀系统包括上下板构件，用于定位相应的上下椎骨的外表面并与其接触的关系。上下板构件包括配合接触表面，其适于彼此接合以保持上下椎骨之间的最小预定牵引距离，并且允许上下板的相对关节运动，枢转运动或侧向运动中的至少一个会员脊椎电镀系统还包括至少一个紧固件，用于将每个上下板构件安装到相应的上下椎骨上。

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