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1. 发明申请

US20070015238A1 Production of pseudotyped recombinant AAV virions 审中-公开
标题翻译：假型重组AAV病毒粒子的生产
公开(公告)号：US20070015238A1
公开(公告)日：2007-01-18
申请号：US10456423
申请日：2003-06-05
申请人： Richard Snyder , Sergie Zolotukhin , Yoshihisa Sakai , Barry Byrne , Mark Potter , Irine Zolotukhin , Scott Loiler , Vince Chiodo , Nicholas Muzyczka , William Hauswirth , Terence Flotte , Corinna Burger , Edgardo Rodriguez
发明人： Richard Snyder , Sergie Zolotukhin , Yoshihisa Sakai , Barry Byrne , Mark Potter , Irine Zolotukhin , Scott Loiler , Vince Chiodo , Nicholas Muzyczka , William Hauswirth , Terence Flotte , Corinna Burger , Edgardo Rodriguez
IPC分类号： C12P21/06 , C12N7/00 , C12N15/861 , C12N5/06
CPC分类号： C12N15/86 , C12N2710/10322 , C12N2750/14143 , C12N2840/20
摘要： Vectors that encode Adeno-Associated Virus (AAV) Rep and Cap proteins of different serotypes and Adenovirus transcription products that provide helper functions were used to produce pseudotyped recombinant AAV (rAAV) virions. Purification methods generated pseudotyped rAAV virion stocks that were 99% pure with titers of 1×1012−1×1013 vector genomes/ml.
摘要翻译：使用编码提供辅助功能的不同血清型和腺病毒转录产物的腺相关病毒（AAV）Rep和Cap蛋白的载体产生假型重组AAV（rAAV）病毒粒子。纯化方法产生99％纯度的假型分离的rAAV病毒颗粒，其滴度为1×10 12×10 13个载体基因组/ ml。

2. 发明授权

US07094604B2 Production of pseudotyped recombinant AAV virions 失效
标题翻译：假型重组AAV病毒粒子的生产
公开(公告)号：US07094604B2
公开(公告)日：2006-08-22
申请号：US10798192
申请日：2004-03-11
申请人： Richard O. Snyder , Sergei Zolotukhin , Yoshihisa Sakai , Barry J. Byrne , Mark R. Potter , Irine Zolotukhin , Scott Loiler , Vince A. Chiodo , Nicholas Muzyczka , William W. Hauswirth , Terence R. Flotte , Corinna Burger , Edgardo Rodriguez , Kevin R. Nash , Thomas J. Fraites
发明人： Richard O. Snyder , Sergei Zolotukhin , Yoshihisa Sakai , Barry J. Byrne , Mark R. Potter , Irine Zolotukhin , Scott Loiler , Vince A. Chiodo , Nicholas Muzyczka , William W. Hauswirth , Terence R. Flotte , Corinna Burger , Edgardo Rodriguez , Kevin R. Nash , Thomas J. Fraites
IPC分类号： C12N5/10 , C12N15/864 , C12N15/35
CPC分类号： C12N15/86 , C12N2710/10322 , C12N2750/14143 , C12N2840/20
摘要： Vectors that encode Adeno-Associated Virus (AAV) Rep and Cap proteins of different serotypes and Adenovirus transcription products that provide helper functions were used to produce pseudotyped recombinant AAV (rAAV) virions. Purification methods generated pseudotyped rAAV virion stocks that were 99% pure with titers of 1×1012–1×1013 vector genomes/ml.
摘要翻译：使用编码提供辅助功能的不同血清型和腺病毒转录产物的腺相关病毒（AAV）Rep和Cap蛋白的载体产生假型重组AAV（rAAV）病毒粒子。纯化方法产生99％纯度的假型分离的rAAV病毒颗粒，其滴度为1×10 12×10 13个载体基因组/ ml。

3. 发明申请

US20090041415A1 DOUBLE-CORE OPTICAL FIBER 审中-公开
标题翻译：双芯光纤
公开(公告)号：US20090041415A1
公开(公告)日：2009-02-12
申请号：US12281469
申请日：2007-03-23
申请人： Hiromasa Tanobe , Yoshihisa Sakai
发明人： Hiromasa Tanobe , Yoshihisa Sakai
IPC分类号： G02B6/036
CPC分类号： G02B6/03661 , G02B6/02042 , G02B6/02047 , G02B6/0283 , G02B6/03605 , G02B6/03616 , G02B6/03627
摘要： A double core optical fiber is provided, in which single mode signal light and multimode signal light can be transmitted and a multimode transmission of the signal light guided through the core can be reduced even when the optical fiber is bent. The double core optical fiber of the present invention includes a core (111) arranged on a central axis of the optical fiber and having a refractive index (112), a first cladding (121) arranged on the outer circumference of the core (111) and having a refractive index (122) smaller than the refractive index (112), and a second cladding arranged on the outer circumference of the first cladding (121) and having a refractive index (132) smaller than the refractive index (122). The core (111) functions as a core for single mode transmission, the core (111) and the first cladding (121) function as a core for multimode transmission, the first cladding (121) function as a cladding for the core for single mode transmission, and the second cladding (132) functions as a cladding for the core for multimode transmission.
摘要翻译：提供双芯光纤，其中可以传输单模信号光和多模信号光，并且即使当光纤弯曲时也可以减少通过芯引导的信号光的多模传输。本发明的双芯光纤包括布置在光纤的中心轴上并具有折射率（112）的芯（111），布置在芯（111）的外圆周上的第一包层（121）并且具有小于折射率（112）的折射率（122），以及布置在第一包层（121）的外圆周上并具有小于折射率（122）的折射率（132）的第二包层。芯（111）用作单模传输的核心，芯（111）和第一包层（121）用作多模传输的核心，第一包层（121）用作用于单模的核的包层传输，并且第二包层（132）用作用于多模传输的芯的包层。

4. 发明授权

US06753996B2 Light-controlled light modulator 失效
标题翻译：光控光调制器
公开(公告)号：US06753996B2
公开(公告)日：2004-06-22
申请号：US09953796
申请日：2001-09-17
申请人： Yasuo Shibata , Yasuhiro Suzuki , Yoshihisa Sakai , Yasumasa Suzaki , Akira Okada , Kazuto Noguchi , Rieko Sato
发明人： Yasuo Shibata , Yasuhiro Suzuki , Yoshihisa Sakai , Yasumasa Suzaki , Akira Okada , Kazuto Noguchi , Rieko Sato
IPC分类号： G02F101
CPC分类号： G02F1/3517 , G02F2/004
摘要： A light-controlled light modulator can achieve high-speed, low-loss wavelength conversion. Continuous light with a wavelength &lgr;j is launched into an MMI coupler via a port, and is split into two parts by the MMI coupler, which are led to a loop-type interferometer. In the loop-type interferometer, the two parts travel separately around the loop as clockwise traveling light and counterclockwise traveling light, are combined by the MMI coupler again via a filter-equipped phase modulator, thereby being emitted to the port. In this state, signal light &lgr;i(s) with a wavelength &lgr;i is launched into the filter-equipped phase modulator via a port. Even when the wavelength &lgr;i of the signal light &lgr;i(s) is equal to the wavelength &lgr;j of the wavelength converted output light, the wavelength conversion can be achieved with preventing noise from being mixed into the output light emitted from a port.
摘要翻译：光控光调制器可以实现高速，低损耗的波长转换。具有波长lambdaj的连续光通过端口发射到MMI耦合器中，并由MMI耦合器分为两部分，其被引导到环型干涉仪。在循环式干涉仪中，两个部件围绕环路分别作为顺时针行进光和逆时针方向的行进光，通过MMI耦合器再次通过配有滤波器的相位调制器组合，从而被发射到端口。在这种状态下，具有波长lambdai的信号灯lambdai通过端口发射到装有滤波器的相位调制器中。即使当信号光的波长长度等于波长转换的输出光的波长lambdaj时，也可以通过防止噪声混入从端口发出的输出光中来实现波长转换。

5. 发明授权

US08244133B2 Optical waveband demultiplexer, optical waveband multiplexer, and optical waveband selective switch 有权
标题翻译：光波段解复用器，光波分复用器和光波段选择开关
公开(公告)号：US08244133B2
公开(公告)日：2012-08-14
申请号：US12226453
申请日：2007-04-18
申请人： Ken-ichi Sato , Hiroshi Hasegawa , Shoji Kakehashi , Osamu Moriwaki , Shin Kamei , Kenya Suzuki , Yoshihisa Sakai , Kouichi Takiguchi
发明人： Ken-ichi Sato , Hiroshi Hasegawa , Shoji Kakehashi , Osamu Moriwaki , Shin Kamei , Kenya Suzuki , Yoshihisa Sakai , Kouichi Takiguchi
IPC分类号： H04J14/02 , H04J14/00 , G02B6/34
CPC分类号： G02B6/12021 , G02B6/3508 , H04J14/02 , H04J14/0212 , H04J14/0213 , H04J14/0217 , H04Q11/0005 , H04Q2011/0032 , H04Q2011/0052 , H04Q2011/0075
摘要： A simple optical waveband multiplexer/demultiplexer operable to separate a wavelength-division multiplexed light beam WDM consisting of a plurality of wavebands WB each including a plurality of optical channels, into a predetermined plurality of wavebands WB, and output the separated plurality of wavebands WB from a plurality of output ports, wherein the wavelength-division multiplexed light beam WDM is transmitted through two array waveguides each capable of performing a demultiplexing function with a resolution corresponding to wavelengths of the optical channels, and a characteristic of sequentially shifting the output ports by one position with shifting of input ports by one position, whereby the wavelength-division multiplexed light beam WDM is separated into a plurality of wavebands WB each including the mutually different optical channels selected from the optical channels included in the wavelength-division multiplexed light beam WDM, and the separated wavebands WB are outputted from the plurality of output ports, respectively.
摘要翻译：一种简单的光波段多路复用器/解复用器，其可操作以将由包括多个光通道的多个波段WB组成的波分复用光束WDM分离成预定的多个波段WB，并将分离的多个波段WB从多个输出端口，其中波分复用光束WDM通过两个阵列波导传输，每个阵列波导能够以与光通道的波长相对应的分辨率执行解复用功能，以及将输出端口依次移位一个将波分复用光束WDM分离为多个波段WB，每个波段WB包括从包括在波分复用光束WDM中的光通道中选择的相互不同的光通道，并输出分离的波段WB d分别来自多个输出端口。

6. 发明授权

US07113701B2 Optical packet routing network system based on optical label switching technique 失效
标题翻译：基于光标签交换技术的光分组路由网络系统
公开(公告)号：US07113701B2
公开(公告)日：2006-09-26
申请号：US10756062
申请日：2004-01-13
申请人： Akira Okada , Kazutoshi Kato , Kazuto Noguchi , Yoshihisa Sakai , Takashi Sakamoto , Morito Matsuoka , Sen-ichi Suzuki
发明人： Akira Okada , Kazutoshi Kato , Kazuto Noguchi , Yoshihisa Sakai , Takashi Sakamoto , Morito Matsuoka , Sen-ichi Suzuki
IPC分类号： H04B10/08 , H04B10/00 , H04J14/00 , H04J14/08
CPC分类号： H04Q11/0005 , H04Q11/0062 , H04Q11/0066 , H04Q2011/0011 , H04Q2011/0016 , H04Q2011/0032 , H04Q2011/0041 , H04Q2011/0069 , H04Q2011/0073 , H04Q2011/0083
摘要： An optical communication equipment comprises shared optical sources 88a–88d to be shared by communication nodes 100a–100d, the wavelengths of optical signals 76a–76d are converted into desired wavelengths λa–λd according to the addressed information of the corresponding optical label signals 77a–77d by using the shared optical sources 88a–88d, and routed to the addressed communication nodes without being converted into electrical signals by using the wavelength routing function of the cyclic-wavelength arrayed-waveguide grating (AWG) 120. The load of each communication node can be reduced by incorporating the multi-wavelength optical sources, which can be shared among individual communication nodes, into the router 80. Further, each communication node is provided with an optical gate or the like for returning the optical signal to the communication node from which the optical signal has been transmitted through the router 80 in order to adjust the transmission time lag between the optical signal and the corresponding optical label signal by the controllers 110a–110d.
摘要翻译：光通信设备包括由通信节点100a -100d共享的共享光源88a -88d，光信号76a -76d的波长根据所寻址的信息被转换成期望的波长λa-lambdad 通过使用共享光源88a -88d对应的光标签信号77a -77d，并且通过使用循环波长阵列波导光栅的波长路由功能被路由到寻址通信节点而不转换成电信号 AWG）120。可以通过将可以在各个通信节点之间共享的多波长光源并入到路由器80中来减少每个通信节点的负载。此外，每个通信节点设置有用于将光信号返回到通过路由器80从其发送光信号的通信节点的光栅等，以便调整光信号和对应的光信号之间的传输时滞控制器110a-110d的光标签信号。

7. 发明授权

US4120644A Apparatus for regeneration of spent active carbon 失效
标题翻译：废活性炭再生装置
公开(公告)号：US4120644A
公开(公告)日：1978-10-17
申请号：US780790
申请日：1977-03-23
申请人： Kouichi Numasaki , Yoshihisa Sakai , Takehiko Nawa , Zenji Matsumoto , Nobutaka Ninomiya
发明人： Kouichi Numasaki , Yoshihisa Sakai , Takehiko Nawa , Zenji Matsumoto , Nobutaka Ninomiya
IPC分类号： C02F1/28 , B01J20/34 , C01B31/08 , F27B15/10 , B01J8/12
CPC分类号： C01B31/088
摘要： The present invention provides a double-cylinder type apparatus for the regeneration of active carbon, which comprises a heating furnace provided with at least one burner and at least one annular regeneration chamber composed of at least one set of an inner cylinder and an outer cylinder installed concentrically inside said heating furnace, said outer cylinder having a plurality of holes penetrating the side wall thereof, wherein the spent active carbon is supplied to the upper part of said annular regeneration chamber and the regenerated carbon is to be taken out at the lower part of the same. The heating of said annular regeneration chamber from the side of said inner cylinder is performed either by introducing the flue gas arising in said heating furnace into the inner cylinder or by providing at least one burner within said inner cylinder and utilizing the combustion gas from said burner. The spent active carbon can be regenerated by subjecting the same to the process comprising drying, calcination and reactivation by the use of the flue gas.
摘要翻译：本发明提供了一种用于再生活性炭的双缸型设备，其包括设置有至少一个燃烧器的加热炉和至少一个环形再生室，所述至少一个环形再生室由至少一组内筒和外筒安装同心地位于所述加热炉内，所述外筒具有穿过其侧壁的多个孔，其中废活性炭被供应到所述环形再生室的上部，并且再生碳将在一样。所述环形再生室从所述内筒一侧的加热通过将在所述加热炉中产生的烟道气引入内圆筒中或通过在所述内圆筒内设置至少一个燃烧器并利用来自所述燃烧器的燃烧气体。废活性炭可以通过使其与含有干燥，煅烧和使用烟道气再活化的方法一起进行再生。

8. 发明授权

US08333517B2 Semiconductor submodule, method for connecting connector and semiconductor submodule, and optical module 有权
标题翻译：半导体子模块，连接器和半导体子模块连接方法以及光模块
公开(公告)号：US08333517B2
公开(公告)日：2012-12-18
申请号：US12525797
申请日：2008-02-04
申请人： Hiromasa Tanobe , Yoshihisa Sakai , Masaru Kobayashi , Ryo Nagase
发明人： Hiromasa Tanobe , Yoshihisa Sakai , Masaru Kobayashi , Ryo Nagase
IPC分类号： G02B6/10 , G02B6/30
CPC分类号： G02B6/4201 , G02B6/423 , G02B6/428 , G02B6/4281 , G02B6/4283 , G02B6/4292 , H01L25/167 , H01L31/0203 , H01L2924/0002 , H01S5/02212 , H01S5/02248 , H01S5/02284 , Y10T29/49826 , H01L2924/00
摘要： A semiconductor submodule includes a substrate (10) as a first substrate having at least one hole, and at least one optical semiconductor device (16) disposed such that light travels through the hole, a substrate (11) as a second substrate having a semiconductor device (26) for driving the optical semiconductor device (16) and amplifying signals and an electrical connector (28) for inputting and outputting electrical signals from and to the outside, and a flexible cable (12) electrically connecting an end of the substrate (10) and an end of the substrate (11) and allowing the first substrate to be folded opposite to the surface on which the optical semiconductor device is mounted.
摘要翻译：半导体子模块包括作为具有至少一个孔的第一基板的基板（10），以及至少一个光学半导体器件（16），其布置成使得光穿过该孔，具有半导体的第二基板的基板（11）用于驱动光学半导体器件（16）和放大信号的器件（26）和用于从外部输入和输出电信号的电连接器（28）以及电连接衬底的端部的柔性电缆（12） 10）和基板（11）的端部，并且允许第一基板与安装光学半导体器件的表面相对地折叠。

9. 发明授权

US08157454B2 Releasable locking mechanism for optical connector 失效
标题翻译：光连接器可释放锁定机构
公开(公告)号：US08157454B2
公开(公告)日：2012-04-17
申请号：US12523839
申请日：2008-02-01
申请人： Toshiyasu Ito , Hiromasa Tanobe , Yoshihisa Sakai , Masaru Kobayashi , Ryo Nagase
发明人： Toshiyasu Ito , Hiromasa Tanobe , Yoshihisa Sakai , Masaru Kobayashi , Ryo Nagase
IPC分类号： G02B6/36
CPC分类号： G02B6/4292 , G02B6/389 , G02B6/4249
摘要： A receptacle (20) detachably accommodating a connector plug (34) connected to optical fibers (32) is rotatably supported by a shaft (14) provided in an installation table (10). The receptacle (20) is biased by a leaf spring (16) for biasing opposite ends of the shaft (14) in one direction. A locking/unlocking mechanism for selectively locking or unlocking the receptacle (20) connected with the connector plug (34) relative to the installation table (10) and a locking mechanism fixing portion (12) includes a locking nib (30Ra) of a lock releasing button (30R), a locking nib (30La) of a lock releasing button (30L), locking nib receiving portions (12na, 12nb) and a coil spring (31).
摘要翻译：可拆卸地容纳连接到光纤（32）的连接器插头（34）的插座（20）由设置在安装台（10）中的轴（14）可旋转地支撑。容器（20）由用于沿一个方向偏压轴（14）的相对端的片簧（16）偏置。用于选择性地锁定或解锁与连接器插头（34）相对于安装台（10）和锁定机构固定部分（12）的插座（20）的锁定/解锁机构包括锁定件的锁定尖头（30Ra）释放按钮（30R），锁定释放按钮（30L）的锁定笔尖（30La），锁定笔尖接收部分（12na，12nb）和螺旋弹簧（31）。

10. 发明申请

US20100074581A1 Semiconductor Submodule, Method for Connecting Connector and Semiconductor Submodule, and Optical Module 有权
标题翻译：半导体子模块，连接器和半导体子模块连接方法以及光模块
公开(公告)号：US20100074581A1
公开(公告)日：2010-03-25
申请号：US12525797
申请日：2008-02-04
申请人： Hiromasa Tanobe , Yoshihisa Sakai , Masaru Kobayashi , Ryo Nagase
发明人： Hiromasa Tanobe , Yoshihisa Sakai , Masaru Kobayashi , Ryo Nagase
IPC分类号： G02B6/36 , H05K1/00 , B23P11/00
CPC分类号： G02B6/4201 , G02B6/423 , G02B6/428 , G02B6/4281 , G02B6/4283 , G02B6/4292 , H01L25/167 , H01L31/0203 , H01L2924/0002 , H01S5/02212 , H01S5/02248 , H01S5/02284 , Y10T29/49826 , H01L2924/00
摘要： A semiconductor submodule includes a substrate (10) as a first substrate having at least one hole, and at least one optical semiconductor device (16) disposed such that light travels through the hole, a substrate (11) as a second substrate having a semiconductor device (26) for driving the optical semiconductor device (16) and amplifying signals and an electrical connector (28) for inputting and outputting electrical signals from and to the outside, and a flexible cable (12) electrically connecting an end of the substrate (10) and an end of the substrate (11) and allowing the first substrate to be folded opposite to the surface on which the optical semiconductor device is mounted.
摘要翻译：半导体子模块包括作为具有至少一个孔的第一基板的基板（10），以及至少一个光学半导体器件（16），其布置成使得光穿过该孔，具有半导体的第二基板的基板（11）用于驱动光学半导体器件（16）和放大信号的器件（26）和用于从外部输入和输出电信号的电连接器（28）以及电连接衬底的端部的柔性电缆（12） 10）和基板（11）的端部，并且允许第一基板与安装光学半导体器件的表面相对地折叠。

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