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    • 10. 发明授权
    • Polymeric medical device systems having shape memory
    • 具有形状记忆的聚合物医疗装置系统
    • US5964744A
    • 1999-10-12
    • US316933
    • 1994-10-03
    • Daniel J. BalbierzJack M. WalkerJoseph R. ThomasRobert S. BleyKevin Van Bladel
    • Daniel J. BalbierzJack M. WalkerJoseph R. ThomasRobert S. BleyKevin Van Bladel
    • A61F2/04A61F2/94A61L27/34A61L27/50A61L31/10A61L31/14A61L31/18A61M25/00A61M25/04A61M25/16
    • A61M27/008A61L27/34A61L27/50A61L31/10A61L31/14A61L31/18A61M25/04A61F2/94A61F2002/041A61L2400/16A61M2025/0293
    • In accordance with the invention, there are provided medical devices with incorporated shape memory systems that allow a polymeric medical device to be inserted in a first conformation or configuration and revert to a second conformation or configuration. The invention is useful in allowing the easy insertion or implantation of a device followed by expansion of the device in order to be retained without expulsion from a body cavity, for example. In another aspect of the invention there is provided a medical device, such as a ureteral stent, that includes comprising an elongated member having a proximal end portion and a distal end portion joined by a body portion. The elongated member has an initial outer diameter. A retention construction serves for retaining the member within a bodily cavity. The member is formulated of a physiologically acceptable polymer capable of hydrating and expanding from the initial member outer diameter to form a final member outer diameter. The device can assume differing shapes and can exhibit different degrees of softening at different places along its length and possess shape memory so that it can be inserted in a first conformation or configuration and revert to a second conformation or configuration upon the occurrence of a triggering event such as hydration.
    • 根据本发明,提供了具有结合的形状记忆系统的医疗装置,其允许聚合物医疗装置以第一构象或构型插入并恢复到第二构象或构型。 本发明可用于允许容易地插入或植入装置,然后扩张装置,以便例如在不从体腔排出的情况下保持。 在本发明的另一方面,提供了一种医疗装置,例如输尿管支架,其包括细长构件,该细长构件具有由主体部分连接的近端部分和远端部分。 细长构件具有初始外径。 保持构造用于将构件保持在身体腔内。 该构件配制有能够从初始构件外径水合和膨胀以形成最终构件外径的生理上可接受的聚合物。 该装置可以呈现不同的形状并且可以在其长度上的不同位置显示不同程度的软化,并且具有形状记忆,使得其可以以第一构象或构型插入并且在发生触发事件时恢复到第二构象或构型 如水合。