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1. 发明申请

US20150173734A1 APPARATUS AND METHOD FOR CONNECTING A CONDUIT TO A HOLLOW ORGAN 审中-公开
标题翻译：将连接连接到中空机构的装置和方法
公开(公告)号：US20150173734A1
公开(公告)日：2015-06-25
申请号：US13556692
申请日：2012-07-24
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, JR.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, JR.
IPC分类号： A61B17/02 , A61B17/3205 , A61F2/06 , A61B17/11
CPC分类号： A61B17/0218 , A61B17/11 , A61B17/320016 , A61B17/32053 , A61B2017/00247 , A61B2017/00252 , A61B2017/00557 , A61B2017/0237 , A61B2017/1107 , A61B2018/00392 , A61F2/064
摘要： An apparatus and method for connecting a first conduit to the heart without cardiopulmonary bypass. The first conduit may be attached to a second conduit having a prosthetic device interposed. The second conduit may then be connected to the aorta. The prosthetic device may be a prosthetic valve (or pump). The apparatus includes an implantable connector with first conduit component, a coring component, a retractor expansion component slidably coupled to the coring component, and a pushing component. The retractor expansion component seats against and separates the inside wall of the left ventricle so that the coring component cuts cleanly through the myocardium, forming a tissue plug. By remaining seated against the inside wall, the retractor expansion component follows the tissue plug into the coring component. The surgeon applies force and rotary motion to the pushing component sufficient to cut the tissue plug and implant the prosthetic component.
摘要翻译：一种用于在没有体外循环的情况下将第一导管连接到心脏的装置和方法。第一导管可以附接到具有插入的假体装置的第二导管。然后可以将第二导管连接到主动脉。假体装置可以是人工瓣膜（或泵）。该装置包括具有第一管道部件的可植入连接器，取芯部件，可滑动地连接到取芯部件的牵开器膨胀部件和推动部件。牵开器扩张部件抵靠并分离左心室的内壁，使得取芯部件干净地穿过心肌，形成组织塞。通过保持抵靠内壁的位置，牵开器膨胀部件沿着组织插塞进入取芯部件。外科医生将力和旋转运动施加到推动部件足以切割组织塞并植入假体部件。

2. 发明授权

US08226670B2 Apparatus and method for connecting a conduit to a hollow organ 失效
标题翻译：将导管连接到中空器官的装置和方法
公开(公告)号：US08226670B2
公开(公告)日：2012-07-24
申请号：US12378585
申请日：2009-02-17
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
IPC分类号： A61B17/11
CPC分类号： A61B17/0218 , A61B17/11 , A61B17/320016 , A61B17/32053 , A61B2017/00247 , A61B2017/00252 , A61B2017/00557 , A61B2017/0237 , A61B2017/1107 , A61B2018/00392 , A61F2/064
摘要： An apparatus and method for connecting a first conduit to the heart without the need for cardiopulmonary bypass. The first conduit may then be attached to a second conduit that has a prosthetic device interposed. The second conduit may then be connected to the aorta. The prosthetic device may be a prosthetic valve or a pump, for example. The apparatus of the present invention includes an implantable connector with first conduit component, a retractor expansion component, a coring component, and a pushing component. The retractor expansion component is slide-ably coupled to the coring component. The retractor expansion component serves to seat against and separate the inside apical wall of the left ventricle so that the coring component may cut cleanly through the myocardium to form a tissue plug without leaving any hanging attachments to the inside walls. By remaining seated against the inside wall, the retractor expansion component follows the tissue plug into the coring component. The surgeon applies force and rotary motion to the pushing component sufficient to cut the tissue plug and implant the prosthetic component.
摘要翻译：一种用于将第一导管连接到心脏而不需要体外循环的装置和方法。然后可以将第一导管连接到插入有假体装置的第二导管。然后可以将第二导管连接到主动脉。假体装置例如可以是人工瓣膜或泵。本发明的装置包括具有第一管道部件的可植入连接器，牵开器膨胀部件，取芯部件和推动部件。牵开器膨胀部件滑动地联接到取芯部件。牵开器膨胀部件用于抵靠和分离左心室的顶端壁，使得取芯部件可以通过心肌切割干净地形成组织塞，而不会将悬挂的附件留在内壁上。通过保持抵靠内壁的位置，牵开器膨胀部件沿着组织插塞进入取芯部件。外科医生将力和旋转运动施加到推动部件足以切割组织塞并植入假体部件。

3. 发明申请

US20100010500A1 Apparatus and method for connecting a conduit to a hollow organ 失效
标题翻译：将导管连接到中空器官的装置和方法
公开(公告)号：US20100010500A1
公开(公告)日：2010-01-14
申请号：US12378585
申请日：2009-02-17
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, JR.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, JR.
IPC分类号： A61F11/00 , A61B17/08
CPC分类号： A61B17/0218 , A61B17/11 , A61B17/320016 , A61B17/32053 , A61B2017/00247 , A61B2017/00252 , A61B2017/00557 , A61B2017/0237 , A61B2017/1107 , A61B2018/00392 , A61F2/064
摘要： An apparatus and method for connecting a first conduit to the heart without the need for cardiopulmonary bypass. The first conduit may then be attached to a second conduit that has a prosthetic device interposed. The second conduit may then be connected to the aorta. The prosthetic device may be a prosthetic valve or a pump, for example. The apparatus of the present invention includes an implantable connector with first conduit component, a retractor expansion component, a coring component, and a pushing component. The retractor expansion component is slide-ably coupled to the coring component. The retractor expansion component serves to seat against and separate the inside apical wall of the left ventricle so that the coring component may cut cleanly through the myocardium to form a tissue plug without leaving any hanging attachments to the inside walls. By remaining seated against the inside wall, the retractor expansion component follows the tissue plug into the coring component. The surgeon applies force and rotary motion to the pushing component sufficient to cut the tissue plug and implant the prosthetic component.
摘要翻译：一种用于将第一导管连接到心脏而不需要体外循环的装置和方法。然后可以将第一导管连接到插入有假体装置的第二导管。然后可以将第二导管连接到主动脉。假体装置例如可以是人工瓣膜或泵。本发明的装置包括具有第一管道部件的可植入连接器，牵开器膨胀部件，取芯部件和推动部件。牵开器膨胀部件滑动地联接到取芯部件。牵开器膨胀部件用于抵靠和分离左心室的顶端壁，使得取芯部件可以通过心肌切割干净地形成组织塞，而不会将悬挂的附件留在内壁上。通过保持抵靠内壁的位置，牵开器膨胀部件沿着组织插塞进入取芯部件。外科医生将力和旋转运动施加到推动部件足以切割组织塞并植入假体部件。

4. 发明申请

US20110118763A1 METHOD AND APPARATUS FOR EFFECTING AN AORTIC VALVE BYPASS, INCLUDING THE PROVISION AND USE OF A T-STENT FOR EFFECTING A DISTAL ANASTOMOSIS FOR THE SAME 审中-公开
标题翻译：用于影响动力阀旁路的方法和装置，包括用于对其进行远距离诊断的T型支架的使用和使用
公开(公告)号：US20110118763A1
公开(公告)日：2011-05-19
申请号：US12829181
申请日：2010-07-01
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Anthony G. Liepert , Joseph L. Smith, JR.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Anthony G. Liepert , Joseph L. Smith, JR.
IPC分类号： A61B17/11
CPC分类号： A61F2/2418 , A61B17/11 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B2017/00252 , A61B2017/1107 , A61B2017/1135 , A61F2/06 , A61F2/064 , A61F2/07 , A61F2/2412 , A61F2/856 , A61F2002/061 , A61F2002/065 , A61M25/09 , A61M25/10 , A61M2025/1052
摘要： A connector for joining a first hollow structure to the side wall of a second hollow structure, the connector comprising: a fluid-constraining tube having a fluid-constraining neck extending therefrom, wherein the tube comprises a lumen having a first opening and a second opening and the neck comprises a lumen having a first opening and a second opening, the neck being joined to the tube so that the neck is in fluid communication with the tube intermediate the length of the tube, such that fluid entering the first opening of the tube can exit the second opening of the tube, and fluid entering the first opening of the neck can exit the second opening of the tube; at least the portions of the tube adjacent to the first opening of the tube and the second opening of the tube being biased radially outwardly so that they normally assume a radially-expanded configuration, but being capable of being restrained in a radially-contracted configuration, wherein the tube is sized so that, when it is in its radially-expanded configuration, it has an outer diameter which is larger than the inner diameter of the second hollow structure.
摘要翻译：一种用于将第一中空结构连接到第二中空结构的侧壁的连接器，所述连接器包括：流体约束管，其具有从其延伸的流体约束颈部，其中所述管包括具有第一开口和第二开口的内腔并且所述颈部包括具有第一开口和第二开口的内腔，所述颈部连接到所述管，使得所述颈部与所述管的中心部分在所述管的中部流体连通，使得流体进入所述管的所述第一开口可以离开管的第二开口，并且进入颈部的第一开口的流体可以离开管的第二开口; 至少管的与管的第一开口相邻的部分和管的第二开口径向向外偏置，使得它们通常呈现径向展开的构造，但是能够被限制在径向缩小的构造中，其特征在于，所述管的尺寸使得当其处于其径向展开形状时，其具有大于所述第二中空结构的内径的外径。

5. 发明授权

US07799041B2 Apparatus and method for forming a hole in a hollow organ 有权
标题翻译：用于在中空器官中形成孔的装置和方法
公开(公告)号：US07799041B2
公开(公告)日：2010-09-21
申请号：US11581081
申请日：2006-10-16
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
IPC分类号： A61B17/11
CPC分类号： A61F2/064 , A61B17/0218 , A61B17/11 , A61B17/320016 , A61B17/32053 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00557 , A61B2017/0237 , A61B2017/1107 , A61B2018/00392
摘要： The invention relates to an apparatus and method for forming a hole in a wall of a hollow organ. The applicator includes a hole forming element for forming a hole in the wall of the organ, a positioning means for positioning the hole forming element, and a retractor element. In addition, the applicator includes a sequencing means for coordinating the relative movement of the retractor element and the hole forming element in a sequential manner to thereby carry out a procedure for forming a hole in the wall of the hollow organ. The sequencing means may further include a safety latch element operatively coupled to the retracting means and the hole forming element. The safety latch of the invention keeps prevents damage to the internal surface of the organ during the formation of the hole.
摘要翻译：本发明涉及一种在中空器官的壁上形成孔的装置和方法。涂抹器包括用于在器官壁中形成孔的孔形成元件，用于定位孔形成元件的定位装置和牵开器元件。另外，涂抹器包括用于以顺序方式协调牵开器元件和孔形成元件的相对运动的排序装置，从而执行在中空器官的壁中形成孔的过程。排序装置还可以包括可操作地联接到缩回装置和孔形成元件的安全闩锁元件。本发明的安全闩锁在孔的形成期间保持防止对器官内表面的损坏。

6. 发明授权

US08679138B2 Apparatus and method for forming a hole in a hollow organ 失效
标题翻译：用于在中空器官中形成孔的装置和方法
公开(公告)号：US08679138B2
公开(公告)日：2014-03-25
申请号：US12924138
申请日：2010-09-21
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
IPC分类号： A61B17/11
CPC分类号： A61F2/064 , A61B17/0218 , A61B17/11 , A61B17/320016 , A61B17/32053 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00557 , A61B2017/0237 , A61B2017/1107 , A61B2018/00392
摘要： The invention relates to an apparatus and method for forming a hole in a wall of a hollow organ. The applicator includes a hole forming element for forming a hole in the wall of the organ, a positioning means for positioning the hole forming element, and a retractor element. In addition, the applicator includes a sequencing means for coordinating the relative movement of the retractor element and the hole forming element in a sequential manner to thereby carry out a procedure for forming a hole in the wall of the hollow organ. The sequencing means may further include a safety latch element operatively coupled to the retracting means and the hole forming element. The safety latch of the invention keeps prevents damage to the internal surface of the organ during the formation of the hole.
摘要翻译：本发明涉及一种在中空器官的壁上形成孔的装置和方法。涂抹器包括用于在器官壁中形成孔的孔形成元件，用于定位孔形成元件的定位装置和牵开器元件。另外，涂抹器包括用于以顺序方式协调牵开器元件和孔形成元件的相对运动的排序装置，从而执行在中空器官的壁中形成孔的过程。排序装置还可以包括可操作地联接到缩回装置和孔形成元件的安全闩锁元件。本发明的安全闩锁在孔的形成期间保持防止对器官内表面的损坏。

7. 发明申请

US20130218261A1 APPARATUS AND METHOD FOR CONNECTING A CONDUIT TO A HOLLOW VESSEL 审中-公开
标题翻译：将管道连接到中空船的装置和方法
公开(公告)号：US20130218261A1
公开(公告)日：2013-08-22
申请号：US13616927
申请日：2012-09-14
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, JR.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, JR.
IPC分类号： A61F2/06 , A61B17/34
CPC分类号： A61F2/06 , A61B17/11 , A61B17/32053 , A61B17/34 , A61B2017/00247 , A61B2017/00252 , A61B2017/00349 , A61B2017/00557 , A61B2017/0061 , A61B2017/1107 , A61B2017/1135 , A61F2/064
摘要： An applicator for forming a hole in a wall of a hollow vessel and engaging a graft, the applicator comprising: a hole forming element adapted to form a hole in the wall of the vessel, the hole forming element comprising a cutting element adapted to cut a hole in the wall of the vessel and a positioning element adapted to hold the position of the applicator relative to the vessel; and an insertion element adapted to be inserted through the wall of the vessel, the insertion element comprising a retraction element adapted to enter into engagement with a graft.
摘要翻译：一种用于在中空容器的壁中形成孔并与移植物接合的施用器，所述施用器包括：适于在所述容器的壁中形成孔的孔形成元件，所述孔形成元件包括切割元件，所述切割元件适于切割在容器的壁中的孔和适于保持施加器相对于容器的位置的定位元件; 以及适于插入通过所述容器的壁的插入元件，所述插入元件包括适于与移植物接合的收回元件。

8. 发明授权

US08277465B2 Apparatus and method for connecting a conduit to a hollow vessel 有权
标题翻译：将管道连接到中空容器的装置和方法
公开(公告)号：US08277465B2
公开(公告)日：2012-10-02
申请号：US11300589
申请日：2005-12-15
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
IPC分类号： A61B17/11
CPC分类号： A61F2/06 , A61B17/11 , A61B17/32053 , A61B17/34 , A61B2017/00247 , A61B2017/00252 , A61B2017/00349 , A61B2017/00557 , A61B2017/0061 , A61B2017/1107 , A61B2017/1135 , A61F2/064
摘要： The present invention provides a system and method for forming a side branch on a hollow vessel, such as the aorta. The side branch is preferably adapted to be connected to a connector conduit, but any other suitable use is also acceptable. The system comprises a graft including a side branch portion, and an applicator comprising a hole forming element adapted to form a hole in the wall of the vessel and an insertion element adapted to be inserted through the wall of the vessel, the insertion element comprising a retraction element adapted to enter into engagement with the graft. The hole forming element may comprise a cutting element adapted to cut a hole in the wall of the vessel, and a positioning element adapted to hold the position of the applicator relative to the vessel. The system further comprises a graft protection element adapted to prevent the graft from being damaged by the cutting element. In this case, the clamping element and the graft protection element may be the same element, for example, an expansion element, which may be expandable from an unexpanded state to fully expanded state and to a partially expanded state. The expansion element may be a balloon, which may be in the shape of a circular toroid, and may include a tension member that restricts the dimensions of the balloon. In addition, the expansion element may be an umbrella mechanism.
摘要翻译：本发明提供一种用于在诸如主动脉的中空容器上形成侧分支的系统和方法。侧分支优选地适于连接到连接器导管，但是任何其它合适的用途也是可接受的。该系统包括包括侧分支部分的移植物和包括适于在容器的壁中形成孔的孔形成元件的施用器和适于插入通过容器的壁的插入元件，插入元件包括适于与移植物接合的收缩元件。孔形成元件可以包括适于切割容器的壁中的孔的切割元件和适于保持施加器相对于容器的位置的定位元件。该系统还包括适于防止移植物被切割元件损坏的移植物保护元件。在这种情况下，夹紧元件和移植物保护元件可以是相同的元件，例如膨胀元件，膨胀元件可以从未膨胀状态扩展到完全膨胀状态并且部分膨胀状态。膨胀元件可以是气球，其可以是环形环形的形状，并且可以包括限制气囊的尺寸的张紧构件。此外，膨胀元件可以是伞式机构。

9. 发明申请

US20110196408A1 Apparatus and method for forming a hole in a hollow organ 失效
标题翻译：用于在中空器官中形成孔的装置和方法
公开(公告)号：US20110196408A1
公开(公告)日：2011-08-11
申请号：US12924138
申请日：2010-09-21
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, JR.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, JR.
IPC分类号： A61B17/32
CPC分类号： A61F2/064 , A61B17/0218 , A61B17/11 , A61B17/320016 , A61B17/32053 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/00557 , A61B2017/0237 , A61B2017/1107 , A61B2018/00392
摘要： The invention relates to an apparatus and method for forming a hole in a wall of a hollow organ. The applicator includes a hole forming element for forming a hole in the wall of the organ, a positioning means for positioning the hole forming element, and a retractor element. In addition, the applicator includes a sequencing means for coordinating the relative movement of the retractor element and the hole forming element in a sequential manner to thereby carry out a procedure for forming a hole in the wall of the hollow organ. The sequencing means may further include a safety latch element operatively coupled to the retracting means and the hole forming element. The safety latch of the invention keeps prevents damage to the internal surface of the organ during the formation of the hole.
摘要翻译：本发明涉及一种在中空器官的壁上形成孔的装置和方法。涂抹器包括用于在器官壁中形成孔的孔形成元件，用于定位孔形成元件的定位装置和牵开器元件。另外，涂抹器包括用于以顺序方式协调牵开器元件和孔形成元件的相对运动的排序装置，从而执行在中空器官的壁中形成孔的过程。排序装置还可以包括可操作地联接到缩回装置和孔形成元件的安全闩锁元件。本发明的安全闩锁在孔的形成期间保持防止对器官内表面的损坏。

10. 发明授权

US07510561B2 Apparatus and method for connecting a conduit to a hollow organ 失效
标题翻译：将导管连接到中空器官的装置和方法
公开(公告)号：US07510561B2
公开(公告)日：2009-03-31
申请号：US11086577
申请日：2005-03-23
申请人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
发明人： Richard M. Beane , John W. Brown , James Alan Crunkleton , James S. Gammie , Joseph L. Smith, Jr.
IPC分类号： A61B17/11
CPC分类号： A61B17/0218 , A61B17/11 , A61B17/320016 , A61B17/32053 , A61B2017/00247 , A61B2017/00252 , A61B2017/00557 , A61B2017/0237 , A61B2017/1107 , A61B2018/00392 , A61F2/064
摘要： An apparatus and method for connecting a first conduit to the heart without the need for cardiopulmonary bypass. The first conduit may then be attached to a second conduit that has a prosthetic device interposed. The second conduit may be connected to the aorta prior to the first conduit being attached to the heart. The prosthetic device may be a prosthetic valve or a pump, for example. The apparatus of the present invention includes an implantable connector with first conduit component, a retractor expansion component, a coring component, and a pushing component. The retractor expansion component is slideably coupled to the coring component. The retractor expansion component serves to seat against and separate the inside apical wall of the left ventricle so that the coring component may cut cleanly through the myocardium to form a tissue plug without leaving any hanging attachments to the inside walls. By remaining seated against the inside wall, the retractor expansion component follows the tissue plug into the coring component. The surgeon applies force and rotary motion to the pushing component sufficient to cut the tissue plug and implant the prosthetic component.
摘要翻译：一种用于将第一导管连接到心脏而不需要体外循环的装置和方法。然后可以将第一导管连接到插入有假体装置的第二导管。第二导管可以在第一导管附接到心脏之前连接到主动脉。假体装置例如可以是人工瓣膜或泵。本发明的装置包括具有第一管道部件的可植入连接器，牵开器膨胀部件，取芯部件和推动部件。牵开器膨胀部件可滑动地联接到取芯部件。牵开器膨胀部件用于抵靠和分离左心室的顶端壁，使得取芯部件可以通过心肌切割干净地形成组织塞，而不会将悬挂的附件留在内壁上。通过保持抵靠内壁的位置，牵开器膨胀部件沿着组织插塞进入取芯部件。外科医生将力和旋转运动施加到推动部件足以切割组织塞并植入假体部件。

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