专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20060088457A1 Ultrasonic counter-current screw extractor for uranium recovery 有权
标题翻译：超声波逆流螺旋提取器，用于铀回收
公开(公告)号：US20060088457A1
公开(公告)日：2006-04-27
申请号：US10883073
申请日：2004-07-01
申请人： Richard Kimura
发明人： Richard Kimura
IPC分类号： C01G56/00
CPC分类号： C01G43/00 , B01D11/0226 , B01D11/0261 , B01D11/0276 , B01D11/0284 , B01F7/00391 , B01F7/021 , C22B3/065 , C22B3/22 , C22B7/007 , C22B7/02 , C22B60/0239 , C22B60/026 , G21F9/30 , Y02P10/234
摘要： An apparatus and method to remove uranium from a body of material wherein the method includes the steps of depositing the body of solid material in an ultrasonic extractor and depositing an amount of acid in the ultrasonic extractor. The method also provides for the steps of heating a jacket of the ultrasonic extractor, transporting the body of solid material in the ultrasonic extractor and the amount of acid such that the body of solid material and the acid contact each other inside the heated ultrasonic extractor while the ultrasonic extractor provides ultrasonic energy to both the body of solid material and the amount of acid, wherein the amount of acid strips uranium from the body of solid material. The method further provides for collecting the amount of acid and the body of solid material in the ultrasonic extractor in different positions, transporting the amount of acid with the stripped uranium to an extraction mixer settler, and settling uranium product from the extraction mixer settler.
摘要翻译：一种从材料体中除去铀的装置和方法，其中所述方法包括以下步骤：将固体物质沉积在超声提取器中并在所述超声提取器中沉积一定量的酸。该方法还提供了加热超声波提取器的护套，在超声波提取器中输送固体材料的体积和酸的量的步骤，使得固体材料和酸的本体在加热的超声波提取器内部彼此接触，同时超声波提取器为固体物质和酸的量提供超声能量，其中酸性条带从固体材料的本体中排出铀。该方法进一步提供了在不同位置收集超声提取器中的固体物质的酸和体积的量，将带有汽提铀的酸的量输送到萃取混合器沉淀器，以及从萃取混合器沉降器沉淀铀产物。

2. 发明授权

US08536301B2 Engineered integrin binding peptides 有权
标题翻译：工程整合素结合肽
公开(公告)号：US08536301B2
公开(公告)日：2013-09-17
申请号：US12418376
申请日：2009-04-03
申请人： Jennifer R. Cochran , Richard Kimura , Aron M. Levin
发明人： Jennifer R. Cochran , Richard Kimura , Aron M. Levin
IPC分类号： A61K38/04
CPC分类号： A61K38/1709 , A61K38/06 , A61K38/08 , A61K45/06 , A61K49/0056 , A61K51/082 , C07K14/47 , G01N33/57492
摘要： Engineered peptides that bind with high affinity (low equilibrium dissociation constant (Kd)) to the cell surface receptors of fibronectin (α5β1) or vitronectin (αvβ3 and αvβ5 integrins) are disclosed. These peptides are based on a molecular scaffold into which a subsequence containing the RGD integrin-binding motif has been inserted. The subsequence (RGD mimic) comprises about 9-13 amino acids, and the RGD contained within the subsequence can be flanked by a variety of amino acids, the sequence of which was determined by sequential rounds of selection (in vitro evolution). The molecular scaffold is preferably based on a knottin, e.g., EETI (Trypsin inhibitor 2 (Trypsin inhibitor II) (EETI-II) [Ecballium elaterium (Jumping cucumber)], AgRP (Agouti-related protein), and Agatoxin IVB, which peptides have a rigidly defined three-dimensional conformation. It is demonstrated that EETI tolerates mutations in other loops and that the present peptides may be used as imaging agents.
摘要翻译：公开了以高亲和力（低平衡解离常数（Kd））结合纤连蛋白（α5beta1）或玻连蛋白（alphavbeta3和alphavbeta5整联蛋白）的细胞表面受体的工程肽。这些肽基于其中插入了含有RGD整联蛋白结合基序的子序列的分子支架。子序列（RGD模拟物）包含约9-13个氨基酸，并且子序列内含有的RGD可以侧接多种氨基酸，其序列通过连续的选择轮次（体外进化）确定。分子支架优选基于knottin，例如EETI（胰蛋白酶抑制剂2（胰蛋白酶抑制剂II）（EETI-II）[Ecballium elaterium（跳跃黄瓜）]，AgRP（Agouti相关蛋白）和Agatoxin IVB，该肽具有刚性定义的三维构象，证明EETI耐受其他环中的突变，并且本发明的肽可以用作成像剂。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式