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1. 发明授权

US06808739B2 Drying method for selectively removing volatile components from wet coatings 失效
标题翻译：用于从湿涂层选择性去除挥发性组分的干燥方法
公开(公告)号：US06808739B2
公开(公告)日：2004-10-26
申请号：US09960132
申请日：2001-09-21
申请人： Richard G. Sitz , Peter T. Benson , Kathleen M. Cooklock , Gary L. Huelsman , Nirmal K. Jain , William Blake Kolb , John M. Sever
发明人： Richard G. Sitz , Peter T. Benson , Kathleen M. Cooklock , Gary L. Huelsman , Nirmal K. Jain , William Blake Kolb , John M. Sever
IPC分类号： B05D134
CPC分类号： A61K9/7061 , B01D5/0066 , F26B3/20 , F26B13/105 , F26B25/006
摘要： Method of selectively removing volatile components from a composition, comprising coating the composition onto a first substrate surface of a substrate, wherein the composition comprises a nonresident volatile component and a resident volatile component. The method further includes positioning at least a portion of the coated substrate between a condensing surface having a condensing surface temperature and a heating surface having a heating surface temperature that is greater than the condensing surface temperature, wherein the condensing surface is in a spaced apart, confronting relationship to the coated surface of the substrate and wherein the heated surface is in thermal contact with a second substrate surface opposite the first substrate surface. In the method, the heated surface temperature and the condensing surface temperature are such that the positioning step causes the nonresident volatile component to be selectively removed from the portion of the coated substrate. The method is suitable for forming transdermal drug delivery compositions.
摘要翻译：从组合物中选择性地除去挥发性组分的方法，包括将组合物涂覆在基材的第一基材表面上，其中所述组合物包含非驻留的挥发性组分和驻留的挥发性组分。该方法还包括将涂覆的基底的至少一部分定位在具有冷凝表面温度的冷凝表面和具有大于冷凝表面温度的加热表面温度的加热表面之间，其中冷凝表面间隔开，与衬底的涂覆表面面对的关系，并且其中加热的表面与与第一衬底表面相对的第二衬底表面热接触。在该方法中，加热的表面温度和冷凝表面温度使得定位步骤使非常规的挥发性组分从涂覆的基底的部分选择性地去除。该方法适用于形成透皮药物递送组合物。

2. 发明授权

US06553689B2 Vapor collection method and apparatus 有权
公开(公告)号：US06553689B2
公开(公告)日：2003-04-29
申请号：US09960131
申请日：2001-09-21
申请人： Nirmal K. Jain , Peter T. Benson , James L. Capps , William Blake Kolb , Eldon E. Lightner , Norman L. Rogers, Jr. , Robert A. Yapel
发明人： Nirmal K. Jain , Peter T. Benson , James L. Capps , William Blake Kolb , Eldon E. Lightner , Norman L. Rogers, Jr. , Robert A. Yapel
IPC分类号： F26B300
CPC分类号： F26B13/005 , F26B25/006
摘要： A vapor collection method and apparatus capable of capturing vapor compositions without substantial dilution. The method and apparatus utilize a material that has a surface with an adjacent gas phase. A chamber is positioned in close proximity to a surface of the material. The position of the chamber creates a relatively small gap between the surface of the material and the chamber. The adjacent gas phase between the chamber and the surface define a region possessing an amount of mass. At least a portion of the mass is drawn through the region by induced flow. The utilization of a small gap limits the flow of mass that is external to the chamber from being swept through the chamber by induced flow.

3. 发明授权

US07971370B2 Vapor collection method and apparatus 有权
标题翻译：蒸汽收集方法和装置
公开(公告)号：US07971370B2
公开(公告)日：2011-07-05
申请号：US11401508
申请日：2006-04-11
申请人： Craig A. Miller , Nirmal K. Jain , William Blake Kolb
发明人： Craig A. Miller , Nirmal K. Jain , William Blake Kolb
IPC分类号： F26B3/00
CPC分类号： F26B13/10 , F26B13/005 , F26B25/006
摘要： An apparatus and method for treating a moving substrate of indefinite length. The apparatus has a control surface positioned in close proximity to a surface of the substrate to define a control gap between the substrate and the control surface. A first chamber is positioned near the control surface, with the first chamber having a gas introduction device. A second chamber is positioned near the control surface, the second chamber having a gas withdrawal device. The control surface and the chambers together define a region wherein the adjacent gas phases possess an amount of mass. Upon inducement of at least a portion of the mass within the region, the mass flow is controlled to significantly reduce dilution of the gas phase component in the adjacent gas phase. This is accomplished through the introduction of a controlled gas stream thereby reducing the flow of an uncontrolled ambient gas stream due to pressure gradients in the system.
摘要翻译：一种用于处理不确定长度的移动基板的装置和方法。所述设备具有位于所述基板的表面附近的控制表面，以限定所述基板和所述控制表面之间的控制间隙。第一室位于控制表面附近，第一室具有气体引入装置。第二室位于控制表面附近，第二室具有气体取出装置。控制表面和室一起限定了一个区域，其中相邻的气相具有一定的质量。在区域内至少一部分质量的诱导下，控制质量流量以显着降低相邻气相中气相成分的稀释。这是通过引入受控气流而实现的，从而由于系统中的压力梯度而降低了不受控制的环境气流的流动。

4. 发明授权

US07918038B2 Vapor collection method and apparatus 有权
公开(公告)号：US07918038B2
公开(公告)日：2011-04-05
申请号：US11366291
申请日：2006-03-02
申请人： Craig A. Miller , Nirmal K. Jain , William Blake Kolb
发明人： Craig A. Miller , Nirmal K. Jain , William Blake Kolb
IPC分类号： F26B3/00
CPC分类号： F26B13/10 , F26B13/005 , F26B25/006
摘要： An apparatus and method for treating a moving substrate of indefinite length. The apparatus has a control surface positioned in close proximity to a surface of the substrate to define a control gap between the substrate and the control surface. A first chamber is positioned near the control surface, with the first chamber having a gas introduction device. A second chamber is positioned near the control surface, the second chamber having a gas withdrawal device. The control surface and the chambers together define a region wherein the adjacent gas phases possess an amount of mass. Upon inducement of at least a portion of the mass within the region, the mass flow is controlled to significantly reduce dilution of the gas phase component in the adjacent gas phase. This is accomplished through the introduction of a controlled gas stream thereby reducing the flow of an uncontrolled ambient gas stream due to pressure gradients in the system.

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