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1. 发明申请

US20080249383A1 ANALYTE SENSING DEVICE HAVING ONE OR MORE SENSING ELECTRODES 审中-公开
标题翻译：具有一个或多个感应电极的分析器感应装置
公开(公告)号：US20080249383A1
公开(公告)日：2008-10-09
申请号：US12062969
申请日：2008-04-04
申请人： Richard G. Sass , W. Kenneth Ward , Robert Bruce , Daniel M. Kaplan
发明人： Richard G. Sass , W. Kenneth Ward , Robert Bruce , Daniel M. Kaplan
IPC分类号： A61B5/1468
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/6848 , A61B5/6849 , A61B17/3468
摘要： Embodiments of the present invention provide an analyte sensing device having one or more sensing electrodes. In embodiments, each sensing electrode may serve as an anode, a cathode, or a combination of an anode and cathode. In embodiments, there may be any suitable number of electrodes. Related analyte sensor insertion aids and methods of using the disclosed embodiments are also provided.
摘要翻译：本发明的实施例提供了具有一个或多个感测电极的分析物感测装置。在实施例中，每个感测电极可以用作阳极，阴极或阳极和阴极的组合。在实施例中，可以存在任何合适数量的电极。还提供了相关的分析物传感器插入辅助器和使用所公开的实施例的方法。

2. 发明申请

US20080287755A1 METHOD AND APPARATUS FOR TREND ALERT CALCULATION AND DISPLAY 审中-公开
标题翻译：用于趋势警报计算和显示的方法和装置
公开(公告)号：US20080287755A1
公开(公告)日：2008-11-20
申请号：US12120400
申请日：2008-05-14
申请人： Richard G. Sass , Daniel M. Kaplan , W. Kenneth Ward
发明人： Richard G. Sass , Daniel M. Kaplan , W. Kenneth Ward
IPC分类号： A61B5/145
CPC分类号： A61B5/14546 , A61B5/14532 , A61B5/7275 , A61B5/7445
摘要： Embodiments of the present invention provide methods, apparatuses, and systems associated with detecting, monitoring, analyzing, and/or displaying analyte level trends in a body. In an embodiment, there is provided a method comprising obtaining a plurality of analyte measurements from a body using an analyte sensing device, and selecting two or more measurements of the plurality of measurements to calculate and display on a device associated with the analyte sensing device a rate of change of the analyte over a period of time spanning the two or more measurements.
摘要翻译：本发明的实施方案提供了与体内检测，监测，分析和/或显示分析物水平趋势相关的方法，装置和系统。在一个实施方案中，提供了一种方法，其包括使用分析物感测装置从身体获得多个分析物测量值，以及选择所述多个测量结果的两个或多个测量值，以在与分析物感测装置相关联的装置上计算和显示分析物在跨越两次或多次测量的时间段内的变化率。

3. 发明申请

US20080139903A1 METHOD AND APPARATUS FOR INSERTION OF A SENSOR USING AN INTRODUCER 审中-公开
标题翻译：使用导引器插入传感器的方法和装置
公开(公告)号：US20080139903A1
公开(公告)日：2008-06-12
申请号：US11952033
申请日：2007-12-06
申请人： Robert Bruce , W. Kenneth Ward , Richard G. Sass , Jon Fortuna , Mark Neinast
发明人： Robert Bruce , W. Kenneth Ward , Richard G. Sass , Jon Fortuna , Mark Neinast
IPC分类号： A61B17/34
CPC分类号： A61B17/3468 , A61B5/14532 , A61B5/1486 , A61B5/6882 , A61B17/3415 , A61B17/3476 , A61B2017/00544 , A61B2017/00548 , A61B2017/3407
摘要： A device and method for delivering a device such as a sensor or fluid transport structure or a fluid transport structure sensor combination into, for example, animal skin. Such a device utilizes an introducer device such as a needle or trocar to puncture skin and allow a sensor to enter through the resultant skin puncture. A device in accordance with embodiments of the present invention includes a housing for mounting to animal skin including an opening for receiving both the distal end of an analyte sensor and the end of an introducer, an actuator device for forcing the introducer from a first position within the housing, through the exit port to a second position, with sufficient force to puncture skin.
摘要翻译：用于将例如传感器或流体输送结构或流体输送结构传感器组合的装置输送到例如动物皮肤的装置和方法。这种装置利用诸如针或套针针的导引装置刺穿皮肤，并允许传感器通过所产生的皮肤穿刺进入。根据本发明的实施例的装置包括用于安装到动物皮肤的壳体，包括用于接收分析物传感器的远端和导引器的端部的开口，用于将导引器从第一位置强迫的致动器装置通过出口到第二位置，壳体具有足够的力刺穿皮肤。

4. 发明授权

US08845530B2 Resposable biosensor assembly and method of sensing 有权
标题翻译：可重复使用的生物传感器组件和感测方法
公开(公告)号：US08845530B2
公开(公告)日：2014-09-30
申请号：US11966685
申请日：2007-12-28
申请人： Robert Bruce , Richard G. Sass , W. Kenneth Ward
发明人： Robert Bruce , Richard G. Sass , W. Kenneth Ward
IPC分类号： A61B5/00 , A61B5/1486 , A61B5/145
CPC分类号： A61B5/14532 , A61B5/0031 , A61B5/14865 , A61B5/6849 , A61B2560/0285 , A61B2560/045
摘要： A device, system, and method for delivering a device such as a sensor or fluid transport structure or a fluid transport structure sensor combination into, for example, mammalian skin and receiving, analyzing, and displaying signals from the device such as a sensor are disclosed. A system in accordance with embodiments of the present invention includes a reusable sensor assembly including a transmitter, microcontroller, and housing plus a disposable sensor assembly including a housing having an opening for receiving both the distal end of a biosensor, a sensor insertion guidance structure, and a transmission apparatus for transmitting signals received from the sensor to a reusable sensor assembly for transmission to an external electronic monitoring unit.
摘要翻译：公开了一种用于将诸如传感器或流体输送结构或流体输送结构传感器组合的装置传送到例如哺乳动物皮肤并且从诸如传感器的装置接收，分析和显示信号的装置，系统和方法。根据本发明的实施例的系统包括可重复使用的传感器组件，其包括发射器，微控制器和壳体以及一次性传感器组件，其包括具有用于接收生物传感器的远端的开口的壳体，传感器插入引导结构，以及发送装置，用于将从所述传感器接收到的信号发送到可重复使用的传感器组件，以传输到外部电子监视单元。

5. 发明申请

US20080269657A1 ADHESIVE OVERBANDAGE 审中-公开
标题翻译：粘合剂超量
公开(公告)号：US20080269657A1
公开(公告)日：2008-10-30
申请号：US12108874
申请日：2008-04-24
申请人： Allen Brenneman , Richard G. Sass , W. Kenneth Ward , Jennifer Matson , Dennis Slomski , Robert Bruce , Leslie Wood , Isaac Federiuk
发明人： Allen Brenneman , Richard G. Sass , W. Kenneth Ward , Jennifer Matson , Dennis Slomski , Robert Bruce , Leslie Wood , Isaac Federiuk
IPC分类号： A61B19/02 , A61F13/02
CPC分类号： A61F15/004 , A61B46/10 , A61B2046/205 , A61F2013/00153 , A61F2013/00544 , A61F2013/0094
摘要： Embodiments of the present invention provide an adhesive overbandage. In an embodiment, there is provided an adhesive overbandage for use with a biosensor. An exemplary overbandage comprises a frame having an upper surface, a lower surface, an outer boundary and an inner boundary, wherein the inner boundary defines an interior opening configured to receive a monitoring device, adhesive disposed on the lower surface of the frame, and a release liner removably coupled to the adhesive.
摘要翻译：本发明的实施例提供了粘合剂过度粘合。在一个实施例中，提供了与生物传感器一起使用的粘合剂过度捆绑。示例性的超宽带包括具有上表面，下表面，外边界和内边界的框架，其中内边界限定被配置为接收监视设备的内部开口，设置在框架的下表面上的粘合剂，以及可拆卸地联接到粘合剂上的释放衬垫。

6. 发明申请

US20120265042A1 METHOD AND APPARATUS FOR INSERTION OF A SENSOR 有权
标题翻译：传感器插入方法和装置
公开(公告)号：US20120265042A1
公开(公告)日：2012-10-18
申请号：US13415828
申请日：2012-03-08
申请人： Mark Neinast , Robert Bruce , W. Kenneth Ward , Richard G. Sass , Jon Fortuna
发明人： Mark Neinast , Robert Bruce , W. Kenneth Ward , Richard G. Sass , Jon Fortuna
IPC分类号： A61B5/1473
CPC分类号： A61B5/6849 , A61B5/14532 , A61B5/1473 , A61B17/3403 , A61B17/3468
摘要： A device and method for delivering a device such as a sensor or fluid transport structure or a fluid transport structure sensor combination into, for example, mammalian skin. Such a device allows a sensor to penetrate mammalian skin without the use of an introducer device such as a needle. A device in accordance with embodiments of the present disclosure includes a housing for attachment to mammalian skin including an exit port for receiving the distal end of a biosensor and an injection activation device including a mechanism for forcing the sensing device from a first position within the housing, through the exit port to a second position, with sufficiently high velocity to partially penetrate the mammalian skin.
摘要翻译：一种用于将例如传感器或流体输送结构或流体输送结构传感器组合的装置输送到例如哺乳动物皮肤的装置和方法。这种装置允许传感器穿透哺乳动物皮肤而不使用诸如针的引入装置。根据本公开的实施例的装置包括用于附接到哺乳动物皮肤的壳体，包括用于接收生物传感器的远端的出口端口和包括用于将感测装置从壳体内的第一位置强制的机构的注射激活装置通过出口到第二位置，具有足够高的速度以部分地穿透哺乳动物皮肤。

7. 发明申请

US20080161656A1 RESPOSABLE BIOSENSOR ASSEMBLY AND METHOD 有权
标题翻译：可再生生物传感器组件和方法
公开(公告)号：US20080161656A1
公开(公告)日：2008-07-03
申请号：US11966685
申请日：2007-12-28
申请人： Robert Bruce , Richard G. Sass , W. Kenneth Ward
发明人： Robert Bruce , Richard G. Sass , W. Kenneth Ward
IPC分类号： A61B5/00
CPC分类号： A61B5/14532 , A61B5/0031 , A61B5/14865 , A61B5/6849 , A61B2560/0285 , A61B2560/045
摘要： A device, system, and method for delivering a device such as a sensor or fluid transport structure or a fluid transport structure sensor combination into, for example, mammalian skin and receiving, analyzing, and displaying signals from the device such as a sensor are disclosed. A system in accordance with embodiments of the present invention includes a reusable sensor assembly including a transmitter, microcontroller, and housing plus disposable sensor assembly including a housing having an opening for receiving both the distal end of a biosensor, a sensor insertion guidance structure, and a transmission apparatus for transmitting signals received from the sensor to a reusable sensor assembly for transmission to an external electronic monitoring unit.
摘要翻译：公开了一种用于将诸如传感器或流体输送结构或流体输送结构传感器组合的装置传送到例如哺乳动物皮肤并且从诸如传感器的装置接收，分析和显示信号的装置，系统和方法。根据本发明的实施例的系统包括可重复使用的传感器组件，其包括发射器，微控制器和壳体以及一次性传感器组件，其包括具有用于接收生物传感器的远端的开口的壳体，传感器插入引导结构和传送装置，用于将从传感器接收的信号发送到可重复使用的传感器组件，以传输到外部电子监视单元。

8. 发明授权

US09615851B2 Method and apparatus for insertion of a sensor 有权
公开(公告)号：US09615851B2
公开(公告)日：2017-04-11
申请号：US13415828
申请日：2012-03-08
申请人： Mark Neinast , Robert Bruce , W. Kenneth Ward , Richard G. Sass , Jon Fortuna
发明人： Mark Neinast , Robert Bruce , W. Kenneth Ward , Richard G. Sass , Jon Fortuna
IPC分类号： A61B5/145 , A61B5/1473 , A61B17/34 , A61B5/00
CPC分类号： A61B5/6849 , A61B5/14532 , A61B5/1473 , A61B17/3403 , A61B17/3468
摘要： A device and method for delivering a device such as a sensor or fluid transport structure or a fluid transport structure sensor combination into, for example, mammalian skin. Such a device allows a sensor to penetrate mammalian skin without the use of an introducer device such as a needle. A device in accordance with embodiments of the present disclosure includes a housing for attachment to mammalian skin including an exit port for receiving the distal end of a biosensor and an injection activation device including a mechanism for forcing the sensing device from a first position within the housing, through the exit port to a second position, with sufficiently high velocity to partially penetrate the mammalian skin.

9. 发明授权

US08187433B2 Compound material analyte sensor 有权
标题翻译：复合材料分析物传感器
公开(公告)号：US08187433B2
公开(公告)日：2012-05-29
申请号：US11538340
申请日：2006-10-03
申请人： W. Kenneth Ward , Richard G. Sass
发明人： W. Kenneth Ward , Richard G. Sass
IPC分类号： C25B11/02 , C25B11/08 , A61B5/05
CPC分类号： A61B5/14865 , A61B5/145 , A61B5/14532 , A61B5/14542 , A61B5/14546 , A61B5/6848 , Y10T29/49
摘要： A sensing element adapted to, at least in part, be inserted into a mammalian body. The sensing element is made up of a core of a structurally robust metal and a plated portion made of an electrochemically active metal conjoined to at least a portion of the core. This sensing element may be used as part of a method for the continuous or intermittent monitoring of an analyte within a mammalian body. The method includes inserting at least a portion of the sensing element into the mammalian body and measuring any electric current produced by at least of portion of the sensor.
摘要翻译：适于至少部分地插入哺乳动物体内的传感元件。感测元件由结构坚固的金属的芯和由结合至芯的至少一部分的电化学活性金属制成的电镀部分构成。该感测元件可以用作用于连续或间歇地监测哺乳动物体内的分析物的方法的一部分。该方法包括将感测元件的至少一部分插入哺乳动物体内并测量由传感器的至少部分产生的任何电流。

10. 发明授权

US07228162B2 Analyte sensor 失效
标题翻译：分析物传感器
公开(公告)号：US07228162B2
公开(公告)日：2007-06-05
申请号：US10342144
申请日：2003-01-13
申请人： W. Kenneth Ward , Richard G. Sass , Mark Nynest , Ellen Anderson , Lawrence B. Jansen
发明人： W. Kenneth Ward , Richard G. Sass , Mark Nynest , Ellen Anderson , Lawrence B. Jansen
IPC分类号： A61B5/05 , A61B5/00
CPC分类号： A61B5/14865 , A61B5/150022 , A61B5/150213 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/15113 , A61B5/15151 , A61B5/15163 , A61B5/157 , A61B5/6848
摘要： A method of measuring an analyte concentration in body fluid in an animal body having skin and subcutaneous soft tissue that includes body fluid. The method comprises, introducing a portion of an analyte-measuring device into the subcutaneous soft tissue. The analyte-measuring device includes an analyte sensing element, having a sharpened distal end to facilitate introduction into the animal body. Additionally the sensing element has an indicating electrode that is adapted to be activated by electric power and to form a raw analyte measurement, when it is activated and in contact with the body fluid, in less than two minutes. The sensing device further has a reference electrode and an electric power and display device that is adapted to mate to the analyte-sensing element. The power and display device activates the analyte-sensing element by applying electric power to it. The analyte-sensing element is introduced into the animal body and is activated by the electric power and display device, thereby causing the analyte-sensing element to form a raw analyte measurement. The power and display device forms and displays a second analyte measurement that is related to the raw analyte measurement, within two minutes of the analyte sensing element being introduced into the body.
摘要翻译：一种测量具有包括体液的皮肤和皮下软组织的动物体内的体液中的分析物浓度的方法。该方法包括将分析物测量装置的一部分引入皮下软组织。分析物测量装置包括分析物传感元件，具有锋利的远端以便于引入动物体内。此外，感测元件具有适于通过电力激活并且在不到两分钟内被激活并与体液接触时形成原始分析物测量的指示电极。感测装置还具有参考电极和适于与分析物感测元件配合的电力和显示装置。功率和显示装置通过向其施加电力来激活分析物感测元件。分析物感测元件被引入动物体内并被电力和显示装置激活，从而使分析物感测元件形成原始分析物测量。功率和显示装置在分析物感测元件被引入体内的两分钟内形成并显示与原始分析物测量相关的第二分析物测量。

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