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1. 发明授权

US4397132A Method for manufacturing a container assembly for storing and dispensing fluid materials 失效
标题翻译：用于制造用于储存和分配流体材料的容器组件的方法
公开(公告)号：US4397132A
公开(公告)日：1983-08-09
申请号：US259495
申请日：1981-05-01
申请人： Greg Pardes , Richard F. Berger , Bernard R. Gerber
发明人： Greg Pardes , Richard F. Berger , Bernard R. Gerber
IPC分类号： B65D83/00 , B65B3/16 , B65B3/24
CPC分类号： B65D83/00
摘要： A method for manufacturing a container assembly adapted to store and dispense fluid material including a collapsible flexible container adapted to be stretched from an initial nominal position and to be collapsed to dispense fluid material stored therein, and a cap member adapted to be placed in operative engagement with a neck portion of the container configured to define a dispensing flow conduit which is placed in direct flow communication with the interior of the container when the cap member is mounted in assembled position on the neck portion of the container. In the manufacture of the container assembly, the container is first stretched from its initial nominal position to expand the volume thereof, and then filled with a fluid material to be stored therein and to be dispensed therefrom while in said stretched position. The cap member is then attached to the container by connecting the cap member in operative engagement with the upper neck portion, and the container is then released from the stretched position and allowed to return to the initial nominal position whereby a quantity of fluid material stored therein commences to be emitted from a check valve at the outlet end of the dispensing flow conduit thereby to completely fill the dispensing flow conduit in the cap member with the fluid material to be dispensed.
摘要翻译：一种用于制造适于储存和分配流体材料的方法，所述容器组件包括可折叠的柔性容器，所述容器适于从初始标称位置被拉伸并且被折叠以分配存储在其中的流体材料;以及帽构件，其适于被放置在操作接合其中容器的颈部被构造成限定分配流动导管，当帽构件安装在容器的颈部上的组装位置时，该分配流动导管与容器的内部直接流动连通。在容器组件的制造中，首先将容器从其初始标称位置拉伸以扩大其体积，然后填充流体材料以在其中被储存并在其处于所述拉伸位置时被分配。然后通过将盖构件与上颈部部分接合而将盖构件附接到容器，然后容器从拉伸位置释放并允许返回到初始标称位置，由此存储一定量的流体材料开始从分配流动管道的出口端处的止回阀排出，从而用要分配的流体材料完全填充盖构件中的分配流动管道。

2. 发明授权

US4424917A Self-cleaning valve 失效
标题翻译：自清洁阀
公开(公告)号：US4424917A
公开(公告)日：1984-01-10
申请号：US269255
申请日：1981-06-01
申请人： Richard F. Berger , Greg Pardes , Bernard R. Gerber
发明人： Richard F. Berger , Greg Pardes , Bernard R. Gerber
IPC分类号： B65D35/46 , B65D83/14 , B65D35/28
CPC分类号： B65D83/14 , B65D35/46
摘要： A self-cleaning valve used at the outlet of a container has an elongated flexible flattenable tube with an inlet end for receiving material to be dispensed from the container and an outlet end for dispensing the material. In the at-rest condition of the valve, a section of the tube extending from the outlet end is supported between a housing surface and a closure-cleaning lever member spring-mounted on the housing so that it pivots about a fulcrum. By pressing down on one end of the lever member, the tube can be opened so that material, forced out of the container, can be dispensed from the outlet end of the tube. After the material has been dispensed, the lever member is pivoted along the outside surface of the tube pressing the tube against the housing surface so that any material remaining within the tube is forced out of the outlet end.
摘要翻译：在容器的出口处使用的自清洁阀具有细长的柔性可压扁管，其具有用于接收从容器分配的材料的入口端和用于分配材料的出口端。在阀的静止状态下，从出口端延伸的管的一部分被支撑在壳体表面和弹簧安装在壳体上的封闭件清洁杆构件之间，使得其围绕支点枢转。通过向下按压杆构件的一端，可以打开管，使得能够从管的出口端分配被迫从容器中排出的材料。在分配材料之后，杠杆构件沿着管的外表面枢转，将管按压住壳体表面，使得留在管内的任何材料被迫离开出口端。

3. 发明授权

US4412632A Self-cleaning valve 失效
标题翻译：自清洁阀
公开(公告)号：US4412632A
公开(公告)日：1983-11-01
申请号：US267876
申请日：1981-05-28
申请人： Richard F. Berger , Greg Pardes , Bernard R. Gerber
发明人： Richard F. Berger , Greg Pardes , Bernard R. Gerber
IPC分类号： B05B15/02 , B65D47/20 , F16K7/02 , F16K25/02 , B05B11/04
CPC分类号： F16K25/02 , B05B15/0291 , B65D47/2031 , F16K7/02
摘要： A self-cleaning valve used at the outlet of a container has an elongated flexible flattenable outlet tube with an inlet for receiving material to be dispensed from the container, and an outlet for dispensing the material. In the at-rest condition of the valve, a pair of spring-biased rollers contact the opposite sides of the tube at a location spaced from the outlet end and hold the tube in a closed condition. When material is forced through the inlet end of the tube it pushes the rollers toward the outlet against the spring biasing action. At the outlet end the rollers separate and permit the tube to open so that the material can be dispensed. After the material has been dispensed, the springs return the rollers to the at-rest position and the rollers effect a self-cleaning action on the tube.
摘要翻译：在容器出口处使用的自清洁阀具有细长的柔性可压扁出口管，其具有用于接收从容器分配的材料的入口和用于分配材料的出口。在阀的静止状态下，一对弹簧偏压辊在与出口端隔开的位置处接触管的相对侧并将管保持在闭合状态。当材料被迫穿过管的入口端时，克服弹簧偏压作用将辊推向出口。在出口端，辊分开并允许管打开，使得材料可以被分配。在材料被分配之后，弹簧将辊子返回到静止位置，并且辊对管子进行自清洁作用。

4. 发明授权

US4392576A Multilayered container including a layer of microcrimped metallic foil 失效
标题翻译：多层容器包括一层微细金属箔
公开(公告)号：US4392576A
公开(公告)日：1983-07-12
申请号：US270244
申请日：1981-06-04
申请人： Richard F. Berger , Greg Pardes , Bernard R. Gerber
发明人： Richard F. Berger , Greg Pardes , Bernard R. Gerber
IPC分类号： B29C49/22 , B32B15/08 , B65D1/02 , B65D23/02
CPC分类号： B65D1/0215 , B29C49/22 , B32B15/08 , B29B2911/14053 , B29B2911/14066 , B29B2911/1408 , B29B2911/14093 , B29B2911/14113 , B29B2911/1412 , B29B2911/14133 , B29B2911/1414 , B29B2911/1424
摘要： A container is formed with a multilayered wall structure including at least one layer of a plastics material and at least one layer of a multidirectionally microcrimped metallic foil. Initially, the wall structure is in the form of a preform or parison incorporating the multilayered wall structure and the preform is blow-molded to the desired shape. The preform can be blow-molded into a container with a complicated wall configuration. The metallic foil is substantially impervious to the passage of gases, vapor, liquids and microorganisms into or out of the container.
摘要翻译：容器形成有多层壁结构，其包括至少一层塑料材料和至少一层多向微剪切的金属箔。最初，壁结构是包含多层壁结构的预成型件或型坯的形式，并且预成型件被吹塑成所需的形状。预成型件可以吹塑成具有复杂壁结构的容器。金属箔基本上不透气体，蒸汽，液体和微生物进入或流出容器。

5. 发明授权

US4415121A Valve for spraying a mist 失效
标题翻译：用于喷雾的阀门
公开(公告)号：US4415121A
公开(公告)日：1983-11-15
申请号：US273023
申请日：1981-06-12
申请人： Richard F. Berger , Greg Pardes , Bernard R. Gerber
发明人： Richard F. Berger , Greg Pardes , Bernard R. Gerber
IPC分类号： B05B11/00 , B05B11/04 , B05B17/06 , B65D47/20 , B05B3/14
CPC分类号： B05B11/007 , B05B11/0072 , B05B11/047 , B05B17/0692 , B65D47/2031
摘要： A valve for spraying material as a mist includes walls forming an elongated passageway having an inlet and an outlet. The passageway is flattened at least at the outlet end. The flattened portion has opposed walls disposed in contact and at least one of the surfaces of the flattened portion has a plurality of capillary-like channels. Upstream from the channels, the valve has a flexible wall section which vibrates at its natural frequency when the material to be sprayed as a mist is forced through the passageway out of the valve.
摘要翻译：用于喷涂材料作为雾的阀包括形成具有入口和出口的细长通道的壁。通道至少在出口端处被压平。平坦部分具有相互接触的相对的壁，扁平部分的至少一个表面具有多个毛细管状通道。在通道的上游，阀门具有柔性的壁部分，当被喷射的材料以雾气的形式被迫穿过阀门的通道时，该部分以其固有的频率振动。

6. 发明授权

US06662977B2 Modular valve assembly and system with airtight, leakproof and shockproof closure for engagement in the neck of a container 失效
标题翻译：模块化阀门组件和系统，具有气密，防漏和防震闭合，用于接合在容器的颈部
公开(公告)号：US06662977B2
公开(公告)日：2003-12-16
申请号：US10100242
申请日：2002-03-14
申请人： Bernard R. Gerber , Jyotirmay Deb
发明人： Bernard R. Gerber , Jyotirmay Deb
IPC分类号： B65D572
CPC分类号： B65D47/205 , B65D47/122
摘要： A modular valve assembly provides an airtight, shockproof, leakproof and evaporation proof closure effective for sealing engagement with the neck or outlet of a flexible or reducible container. The modular valve assembly is effective in preventing: (1) leakage of fluids from the container due to vibration or changes in temperature or pressure; (2) any backflow or reentry of contaminants through the valve assembly, including air; and (3) evaporation of fluid from the container. If the fluid initially is sterile, the closure maintains the sterility of the remaining fluid in the container during and between dispensings of the fluid. Thus, the modular valve assembly extends the useful life of the fluid in the container to its shelf life. Although the user makes many dispensings from it, the container behaves as though she or he had never opened it. Thermostable fluids delivered through this modular valve assembly have no need for preservatives or refrigeration.
摘要翻译：模块化阀组件提供气密，防震，防漏和防蒸汽封闭，有效地与柔性或可还原容器的颈部或出口密封接合。模块化阀组件有效地防止：（1）由于振动或温度或压力变化而导致流体从容器泄漏; （2）通过阀门组件（包括空气）的任何回流或再入污染物; 和（3）从容器蒸发流体。如果流体最初是无菌的，则封闭物在流体分配期间和之间保持容器中剩余流体的无菌性。因此，模块化阀组件将容器中流体的使用寿命延长到其保质期。尽管用户从中进行许多分配，但容器的行为就好像她还是从未打开过。通过该模块化阀组件输送的热稳定流体不需要防腐剂或制冷剂。

7. 发明授权

US6079449A System for delivering and maintaining the sterility and integrity of flowable materials 失效
标题翻译：用于输送和维持可流动材料的不整洁性和完整性的系统
公开(公告)号：US6079449A
公开(公告)日：2000-06-27
申请号：US241178
申请日：1999-02-01
申请人： Bernard R. Gerber
发明人： Bernard R. Gerber
IPC分类号： B65D83/00 , B65D35/02 , B65D35/24 , B65D47/04 , B65D47/20 , B67D1/14 , F16K15/14 , F16K24/04 , F16K25/00 , F16L55/00 , B65D5/72
CPC分类号： B65D47/2081 , F16K15/145 , Y10T137/7842 , Y10T137/7882 , Y10T137/7895
摘要： A system is provided for contamination free delivery and control of a flowable medium contained in an enclosed flow path or a container. The system is highly scalable in size and works even with viscous fluids which are difficult to flow. The device enables a flowable material to be formulated without anti-oxidants, preservatives or anti microbial agents. This provides the advantage of an enhanced therapeutic effect for many medications, especially those which are considered labile. The device also preserves the integrity and sterility of a flowable material contained in an enclosed flow path such as blood plasma, and is effective against microbial as well as viral challenges. The device can be used to maintain the carbonation of a carbonated flowable medium. The system provides a seat and reversibly deformable seal disposed in the flow path; wherein the seal and seat are moveable between a closed and open state upon the deformation of the seal. In the closed state, the sealing surface between the seal and seat entraps one or more layers of the flowable material which forms a bonding action between the seal and seat to prevent entry of external matter into the flow path while at the same time forming a barrier against the back flow migration of contaminating matter.
摘要翻译：提供了一种用于无污染输送和控制包含在封闭流动路径或容器中的可流动介质的系统。该系统尺寸高度可扩展，即使是难以流动的粘性流体也可以工作。该装置使得可流动的材料配制而不含抗氧化剂，防腐剂或抗微生物剂。这提供了许多药物的增强的治疗效果的优点，特别是被认为是不稳定的药物。该装置还保持包含在诸如血浆的封闭流动路径中的可流动材料的完整性和无菌性，并且有效抵抗微生物以及病毒挑战。该装置可用于维持碳酸化可流动介质的碳酸化。该系统提供设置在流路中的座椅和可逆变形的密封件; 其中所述密封件和所述座可在所述密封件变形时在闭合和打开状态之间移动。在关闭状态下，密封件和阀座之间的密封表面捕获一层或多层可流动材料，其形成密封件和阀座之间的结合作用，以防止外部物质进入流动路径，同时形成阻挡层防止污染物质的回流迁移。

8. 发明授权

US06286725B1 Contamination-safe multi-dose dispensing and delivery system for flowable materials 失效
标题翻译：可流动材料的污染安全多剂量分配和输送系统
公开(公告)号：US06286725B1
公开(公告)日：2001-09-11
申请号：US08934040
申请日：1997-09-19
申请人： Bernard R. Gerber
发明人： Bernard R. Gerber
IPC分类号： B65D3700
CPC分类号： B65D47/2075 , B65D47/2031
摘要： A valve for dispensing the fluid contents of a container such that external contaminants such as dust, air or microbes cannot enter the container even after repeated dispensing cycles. The valve comprises a plug-type valve and an elastomeric sheath type valve such as a flapper valve, slit valve, or duck bill valve. All are one-way devices. The plug is provided with a mechanism for resetting it to the closed position at the end of each delivery cycle such that the plug is a one-way device also. The mechanism can be an elastomeric tether, gravity, or the deformation of a valve part. The plug can be provided with channels or other cut or shaped features, e.g. grooves, to facilitate fluid flow. The container used with this invention must be volumetrically reducible and thereby maintain its own internal pressure at the end of a delivery cycle. Alternatively, the valve of the present invention can be made without the outlet valve i.e., the flapper, slit, or duck bill valve. In this case, the plug is the only one-way valve mechanism.
摘要翻译：用于分配容器的流体内容物的阀，使得即使在重复分配循环之后，诸如灰尘，空气或微生物的外部污染物也不能进入容器。该阀包括插塞式阀和弹性护套型阀，例如挡板阀，狭缝阀或鸭嘴阀。都是单向设备。插头设置有用于在每个传送周期结束时将其复位到关闭位置的机构，使得插头也是单向设备。该机构可以是弹性系链，重力或阀部件的变形。塞子可以设置有通道或其它切割或成形的特征，例如。槽，以便于流体流动。与本发明一起使用的容器必须是体积可还原的，从而在输送循环结束时保持其自身的内部压力。或者，本发明的阀也可以没有出口阀，即挡板，狭缝或鸭嘴阀。在这种情况下，插头是唯一的单向阀机构。

9. 发明授权

US06202901B1 Modular microbarrier™ cap delivery system for attachment to the neck of a container 失效
标题翻译：用于连接到容器颈部的模块化微阻挡（TM）帽输送系统
公开(公告)号：US06202901B1
公开(公告)日：2001-03-20
申请号：US09511694
申请日：2000-02-23
申请人： Bernard R. Gerber , Jyotirmay Deb
发明人： Bernard R. Gerber , Jyotirmay Deb
IPC分类号： B65D572
CPC分类号： B65D47/2081 , F16K15/145 , Y10T137/7842 , Y10T137/7882 , Y10T137/7895
摘要： A modular cap delivery system comprising an elastomeric seal and conformably engaging seat can be affixed to or integrated in the neck of a container such as a bottle, flexible bag, tube, or any container having a neck and holding a quantity of a flowable medium. The configuration of the seal and seat eliminate the influx of air, airborne pathogens, or any contaminant into the container of flowable medium to which the delivery device is attached, thereby maintaining the integrity and sterility of a flowable material, even when challenged by direct contact through immersion in suspensions of bacteria or viruses. The delivery device is highly scalable in size, can work for viscous fluids that are difficult to flow, and enables a flowable material to be reformulated without preservatives or antioxidants. This provides the advantage of an enhanced therapeutic effect for many medications, particularly eye care solutions. The sterility of a product such as Ultra High Temperature (UHT) milk and other dairy products can be maintained without the need for refrigeration. When used as a cap for fitment over a bottle of wine, it can substantially prevent oxidation and degradation of wine after the container is opened. The delivery system also can be used to maintain the carbonation of soft drinks, beer, or the like, even over repeated usage thereby prolonging the useful life of a carbonated beverage substantially to that of the beverage's shelf life.
摘要翻译：包括弹性体密封件和顺应性接合的座椅的模块化盖子输送系统可以固定到或集成在诸如瓶子，柔性袋子，管子或具有颈部并且保持一定量的可流动介质的容器的容器的颈部中。密封和座位的结构可以消除空气，空气传播的病原体或任何污染物流入与输送装置相连的流动介质的容器中，从而保持可流动材料的完整性和不可靠性，即使在直接接触的情况下通过浸入细菌或病毒的悬浮液中。输送装置尺寸高度可扩展，可用于难以流动的粘性流体，并且使可流动的材料在不含防腐剂或抗氧化剂的情况下重新配制。这提供了许多药物，特别是眼部护理溶液的增强的治疗效果的优点。可以维持超高温（UHT）牛奶和其他乳制品等产品的无菌性，无需制冷。当用作一瓶用于装在一瓶葡萄酒上的盖子时，它可以在容器打开之后基本上防止葡萄酒的氧化和降解。输送系统也可以用于维持软饮料，啤酒等的碳酸化，甚至重复使用，从而延长了碳酸饮料的使用寿命，大大提高了饮料的保质期。

10. 发明授权

US5836484A Contamination-safe multiple-dose dispensing cartridge for flowable materials 失效
标题翻译：用于可流动材料的污染安全多剂量分配盒
公开(公告)号：US5836484A
公开(公告)日：1998-11-17
申请号：US724975
申请日：1996-10-03
申请人： Bernard R. Gerber
发明人： Bernard R. Gerber
IPC分类号： B65D35/50 , B65D47/20 , B65D5/72
CPC分类号： B65D47/205
摘要： A dispensing cartridge is designed to dispense multiple doses of a flowable material from a collapsible container, i.e., from a container of the type which does not produce an internal vacuum as the flowable material is dispensed. The cartridge has a housing for protecting a delivery block enveloped by an elastic sheath. The delivery block receives the flowable material from the collapsible container through an input port and delivers it through an internal channel with branches to at least one output port. Sleeve valves are created at the output port or ports by the sheath. In a preferred embodiment an end of the sheath forms an outlet valve downstream of the sleeve valves. The cartridge prevents external contaminants such as air and its constituents, oxygen, nitrogen, water vapor and other atmospheric gases as well as other air-borne contaminants including smoke, dust, pollen and microorganisms from entering the container and can be mounted on tubes, bags, infusion containers, syringes, pouches, collapsible reservoirs, bellows-type containers and the like. In a particularly advantageous embodiment the dispensing cartridge is permanently bonded to the container to produce an integrated dispensing system.
摘要翻译：分配盒被设计成从可折叠容器中分配多个剂量的可流动材料，即从分配可流动材料时不产生内部真空的容器。盒具有用于保护由弹性护套包围的输送块的壳体。输送块通过输入端口从可收缩容器接收可流动材料，并将其通过具有分支的内部通道输送到至少一个输出端口。套管由输出口或端口由护套产生。在优选实施例中，护套的端部在套筒阀的下游形成出口阀。墨盒防止外部污染物如空气及其成分，氧气，氮气，水蒸气和其他大气气体以及其他空气污染物，包括烟雾，粉尘，花粉和微生物进入容器，并可以安装在管，袋输液容器，注射器，袋，可折叠储存器，波纹管式容器等。在特别有利的实施例中，分配盒永久地结合到容器以产生一体化分配系统。

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