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    • 4. 发明申请
    • METHOD FOR ENHANCING THE RESOLVING POWER OF ION MOBILITY SEPARATIONS OVER A LIMITED MOBILITY RANGE
    • 提高移动能力分离功能的方法,有限的移动范围
    • US20130299690A1
    • 2013-11-14
    • US13861511
    • 2013-04-12
    • Alexandre A. ShvartsburgKeqi TangRichard D. Smith
    • Alexandre A. ShvartsburgKeqi TangRichard D. Smith
    • H01J49/00
    • H01J49/0031G01N27/622
    • A method for raising the resolving power, specificity, and peak capacity of conventional ion mobility spectrometry is disclosed. Ions are separated in a dynamic electric field comprising an oscillatory field wave and opposing static field, or at least two counter propagating waves with different parameters (amplitude, profile, frequency, or speed). As the functional dependencies of mean drift velocity on the ion mobility in a wave and static field or in unequal waves differ, only single species is equilibrated while others drift in either direction and are mobility-separated. An ion mobility spectrum over a limited range is then acquired by measuring ion drift times through a fixed distance inside the gas-filled enclosure. The resolving power in the vicinity of equilibrium mobility substantially exceeds that for known traveling-wave or drift-tube IMS separations, with spectra over wider ranges obtainable by stitching multiple segments. The approach also enables low-cutoff, high-cutoff, and bandpass ion mobility filters.
    • 公开了提高常规离子迁移光谱法的分辨能力,特异性和峰值能力的方法。 离子在包括振荡场波和相对静电场的动态电场中分离,或至少两个具有不同参数(幅度,分布,频率或速度)的反向传播波。 由于平均漂移速度对波和静电场或不相等波的离子迁移率的功能依赖性不同,只有单个物质平衡,而其他物质在任一方向上漂移并且是迁移率分离的。 然后通过在充满气体的外壳内的固定距离测量离子漂移时间来获得在有限范围内的离子迁移谱。 在平衡迁移附近的分辨能力基本上超过已知的行波或漂移管IMS分离的分辨能力,其中可以通过缝合多个段获得更宽范围的光谱。 该方法还可实现低截止,高截止和带通离子迁移率滤波器。
    • 5. 发明授权
    • Mesh chair with open-end hoop
    • 网椅带开口箍
    • US08454093B2
    • 2013-06-04
    • US12748823
    • 2010-03-29
    • Richard D. Smith
    • Richard D. Smith
    • A47C7/00
    • A47C3/04A47C4/28A47C4/48A47C7/282
    • A folding or stacking chair has a seat and a backrest carried between opposite frame sides each with a backrest support, a front leg and a rear leg. One or both of the seat and the backrest has a continuous sheet of flexible and elastic knitted mesh or patterned open texture plastic held across and substantially covering an opening in an open-end hoop coupled between the frame sides. An open-end of the hoop faces in a front or a back orientation for the seat, or a top or a bottom orientation for the backrest, with sides of the hoop attached to the frame sides. The sheet of mesh or textured plastic has a finished edge spanning the open-end of the hoop.
    • 折叠或折叠椅子具有座椅和靠背,其在相对的框架侧面之间承载,每个座椅具有靠背支撑件,前腿部和后腿部。 座椅和靠背中的一个或两个具有柔性和弹性的针织网或图案化的开放纹理塑料的连续片,该织物保持横跨并且基本上覆盖耦合在框架侧之间的开口箍中的开口。 箍的开口端面朝向座椅的前方或后方,或用于靠背的顶部或底部方向,箍的侧面连接到框架侧。 网状或纹理化的塑料片具有跨越箍的开口端的成品边缘。
    • 6. 发明授权
    • Folding mesh chair with nesting hoops
    • 折叠网椅与嵌套箍
    • US08038221B2
    • 2011-10-18
    • US12422821
    • 2009-04-13
    • Richard D. SmithOrrin C. Farnsworth
    • Richard D. SmithOrrin C. Farnsworth
    • A47C7/00
    • A47C4/44A47C3/04A47C4/28A47C4/38A47C5/06A47C7/002A47C7/282
    • A folding mesh chair includes a seat and a backrest carried between opposite frame sides. The chair has an unfolded seating position in which the seat pivots to extend from the frame sides and bottoms of front and rear legs move apart, and a folded position in which the seat pivots toward the frame sides and the front and rear legs move together. One or both of the seat and the backrest have a continuous sheet of flexible and elastic mesh or patterned open texture plastic held across and substantially covering an opening in an all-plastic hoop fixed between the frame sides. The hoop includes inner and outer plastic mating hoops with the mesh extending over an outer perimeter of the inner hoop and into an interface between the inner and outer hoops.
    • 折叠网椅包括座位和靠在相对的框架侧之间的靠背。 椅子具有展开的就座位置,其中座椅从框架侧面枢转并从前腿和后腿的底部移开,折叠位置,座位朝向框架侧摆动,前后腿一起移动。 座椅和靠背中的一个或两个具有连续的柔性和弹性网格片或图案化的开放纹理塑料,其保持横跨并且基本上覆盖固定在框架侧之间的全塑性环箍中的开口。 箍包括内部和外部塑料配合箍,其中网状物在内箍的外周延伸并且进入内圈和外箍之间的界面。
    • 10. 发明申请
    • METHOD AND APPARATUS FOR SELECTIVE FILTERING OF IONS
    • 选择性过滤离子的方法和装置
    • US20090108194A1
    • 2009-04-30
    • US11251529
    • 2005-09-30
    • Jason S. PageKeqi TangRichard D. Smith
    • Jason S. PageKeqi TangRichard D. Smith
    • B01D59/44
    • H01J49/066G01N27/622
    • An adjustable, low mass-to-charge (m/z) filter is disclosed employing electrospray ionization to block ions associated with unwanted low m/z species from entering the mass spectrometer and contributing their space charge to down-stream ion accumulation steps. The low-mass filter is made by using an adjustable potential energy barrier from the conductance limiting terminal electrode of an electrodynamic ion funnel, which prohibits species with higher ion mobilities from being transmitted. The filter provides a linear voltage adjustment of low-mass filtering from m/z values from about 50 to about 500. Mass filtering above m/z 500 can also be performed; however, higher m/z species are attenuated. The mass filter was evaluated with a liquid chromatography-mass spectrometry analysis of an albumin tryptic digest and resulted in the ability to block low-mass, “background” ions which account for 40-70% of the total ion current from the ESI source during peak elution.
    • 公开了一种可调节的低质量 - 电荷(m / z)滤波器,其使用电喷雾电离来阻挡与不想要的低m / z物质相关的离子进入质谱仪并且为下游离子累积步骤贡献其空间电荷。 低质量过滤器通过使用来自电动离子漏斗的电导限制端子电极的可调势势垒来制造,其阻止具有较高离子迁移率的物质被传输。 滤波器提供从大约50到大约500的m / z值的低质量滤波的线性电压调节。也可以执行m / z 500以上的质量过滤; 然而,更高的m / z物种减弱。 通过对白蛋白胰蛋白酶消化物的液相色谱 - 质谱分析来评估质量过滤器,并且导致阻断低质量“背景”离子的能力,其占离子源的总离子电流的40-70% 峰洗脱。