专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US4946949A Polymerizable aromatic-azo-aliphatic compounds and polymers made therefrom 失效
标题翻译：可聚合的芳族 - 偶氮 - 脂族化合物和由其制备的聚合物
公开(公告)号：US4946949A
公开(公告)日：1990-08-07
申请号：US211194
申请日：1988-06-24
申请人： Richard A. Wolf , Alan E. Platt
发明人： Richard A. Wolf , Alan E. Platt
IPC分类号： C07C245/06 , C08F8/00 , C08F12/26
CPC分类号： C08F12/26 , C07C245/06 , C08F8/00
摘要： Compounds which comprise an azo group linking an aliphatic group to an olefin-bearing aromatic group, for example t-butylazostyrene, can be polymerized at temperatures of 130.degree. C. or more without causing substantial thermal decomposition of the azo group. The compounds and their polymers may be stored indefinitely at ambient temperatures. The azo group in the polymer will decompose at temperatures in excess of 240.degree. C. to become a free radical initiator or cross-linking agent.
摘要翻译：包含连接脂族基团和含烯烃芳族基团的偶氮基团的化合物，例如叔丁基苯基苯乙烯，可以在130℃或更高的温度下聚合，而不引起偶氮基团的实质的热分解。化合物及其聚合物可以无限期地存储在环境温度下。聚合物中的偶氮基将在超过240℃的温度下分解，成为自由基引发剂或交联剂。

2. 发明授权

US06348597B2 Intermediates useful for the preparation of antihistaminic piperidine derivatives 失效
标题翻译：用于制备抗组胺型哌啶衍生物的中间体
公开(公告)号：US06348597B2
公开(公告)日：2002-02-19
申请号：US09824788
申请日：2001-04-04
申请人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
发明人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
IPC分类号： C07D21114
CPC分类号： C07D295/185 , C07C33/46 , C07C45/46 , C07C45/63 , C07C45/65 , C07C45/673 , C07C49/792 , C07C49/798 , C07C49/80 , C07C49/813 , C07C49/82 , C07C49/825 , C07C49/83 , C07C49/835 , C07C49/86 , C07C59/86 , C07C59/88 , C07C69/007 , C07C69/738 , C07C235/78 , C07C255/16 , C07C259/06 , C07C2601/02 , C07D211/22 , C07D401/06 , C07D401/10
摘要： The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents —C(═O)— or —CH(OH)—; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, m is an integer 0.
摘要翻译：本发明涉及一种新的中间体和方法，其可用于制备W代表-C（= O） - 或-CH（OH） - 的某些抗组胺型哌啶衍生物; R 1表示氢或羟基; R 2表示氢 R 1和R 2一起形成在具有R 1和R 2的碳原子之间的第二个键; n是1至5的整数; m是整数0或1; R 3是-COOH或-COO烷基，其中烷基部分具有 1至6个碳原子，并且是直链或支链的，每个A是氢或羟基; 和其药学上可接受的盐和单独的光学异构体，条件是其中R 1和R 2一起形成在具有R 1和R 2的碳原子之间或其中R 1表示羟基的第二个键，m是整数0。

3. 发明授权

US06777555B2 Intermediates useful for the preparation of antihistaminic piperidine derivatives 失效
标题翻译：用于制备抗组胺型哌啶衍生物的中间体
公开(公告)号：US06777555B2
公开(公告)日：2004-08-17
申请号：US10364641
申请日：2003-02-12
申请人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
发明人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
IPC分类号： C07D21114
CPC分类号： C07D295/185 , C07C33/46 , C07C45/46 , C07C45/63 , C07C45/65 , C07C45/673 , C07C49/792 , C07C49/798 , C07C49/80 , C07C49/813 , C07C49/82 , C07C49/825 , C07C49/83 , C07C49/835 , C07C49/86 , C07C59/86 , C07C59/88 , C07C69/007 , C07C69/738 , C07C235/78 , C07C255/16 , C07C259/06 , C07C2601/02 , C07D211/22 , C07D401/06 , C07D401/10
摘要： The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents —C(═O)— or —CH(OH)—; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, n is an integer 0.
摘要翻译：本发明涉及一种新的中间体和方法，其可用于制备W代表-C（= O） - 或-CH（OH） - 的某些抗组胺型哌啶衍生物; R 1表示氢或羟基; R 2表示氢 R 1和R 2一起形成在具有R 1和R 2的碳原子之间的第二个键; n是1至5的整数; m是整数0或1; R 3是-COOH或-COO烷基，其中烷基部分具有 1至6个碳原子，并且是直链或支链的，每个A是氢或羟基; 其药学上可接受的盐和单独的光学异构体，条件是其中R 1和R 2一起形成在具有R 1和R 2的碳原子之间或其中R 1表示羟基的第二个键，n是整数0。

4. 发明授权

US6147216A Intermediates useful for the preparation of antihistaminic piperidine derivatives 失效
标题翻译：用于制备抗组胺型哌啶衍生物的中间体
公开(公告)号：US6147216A
公开(公告)日：2000-11-14
申请号：US458747
申请日：1995-06-02
申请人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
发明人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
IPC分类号： C07C45/46 , C07C45/63 , C07C45/65 , C07C45/67 , C07C49/792 , C07C49/798 , C07C49/80 , C07C49/813 , C07C49/82 , C07C49/825 , C07C49/83 , C07C49/835 , C07C49/86 , C07C59/86 , C07C59/88 , C07C69/007 , C07C69/738 , C07C235/78 , C07C255/16 , C07C259/06 , C07D211/22 , C07D295/185 , C07D401/06 , C07D401/10 , C07D211/14
CPC分类号： C07D295/185 , C07C235/78 , C07C255/16 , C07C259/06 , C07C45/46 , C07C45/63 , C07C45/65 , C07C45/673 , C07C49/792 , C07C49/798 , C07C49/80 , C07C49/813 , C07C49/82 , C07C49/825 , C07C49/83 , C07C49/835 , C07C49/86 , C07C59/86 , C07C59/88 , C07C69/007 , C07C69/738 , C07D211/22 , C07D401/06 , C07D401/10 , C07C2101/02
摘要： The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula ##STR1## wherein W represents --C(.dbd.O)-- or --CH(OH)--;R.sub.1 represents hydrogen or hydroxy;R.sub.2 represents hydrogen;R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ;n is an integer of from 1 to 5;m is an integer 0 or 1;R.sub.3 is --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; andpharmaceutically acceptable salts and individual optical isomers thereof,with the proviso that where R.sub.1 and R.sub.2 are ta to form a second bond between the carbon R.sub.1 and R.sub.2 or where R.sub.1 represented hydroxy integer 0.
摘要翻译：本发明涉及可用于制备下式其中W代表-C（= O） - 或-CH（OH） - 的某些抗组氨酸哌啶衍生物的新中间体和方法; R1代表氢或羟基; R2表示氢; R1和R2一起形成带有R1和R2的碳原子之间的第二个键; n为1〜5的整数， m为整数0或1; R3是-COOH或-COO烷基，其中烷基部分具有1至6个碳原子，并且是直链或支链的，每个A是氢或羟基; 以及其药学上可接受的盐和单独的光学异构体，条件是其中R 1和R 2为ta以在碳R 1和R 2之间形成第二个键，或其中R 1表示羟基整数0。

5. 发明授权

US5080171A Method of treating subterranean formation with a composition of improved viscosity control 失效
标题翻译：用改进的粘度控制组合物处理地层的方法
公开(公告)号：US5080171A
公开(公告)日：1992-01-14
申请号：US610646
申请日：1990-11-08
申请人： Richard A. Wolf , Thomas L. Staples
发明人： Richard A. Wolf , Thomas L. Staples
IPC分类号： C09K8/62
CPC分类号： C09K8/62 , Y10S507/921
摘要： Nitrogen containing free radical sources such as diazenes are useful as breakers in fracturing fluids used in the recovery of oil and gas from subterranean formations.
摘要翻译：含氮自由基源如二氮烯可用作在地层中回收油和气的压裂液中的破碎剂。

6. 发明授权

US5037925A Polymers containing aromatic-azo-aliphatic moieties capable of generating photoinitiated free radicals 失效
标题翻译：含有能产生光引发自由基的芳族 - 偶氮 - 脂族部分的聚合物
公开(公告)号：US5037925A
公开(公告)日：1991-08-06
申请号：US492701
申请日：1990-03-13
申请人： Richard A. Wolf , Paul V. Grosso
发明人： Richard A. Wolf , Paul V. Grosso
IPC分类号： C07C245/06 , C08F12/26
CPC分类号： C07C245/06 , C08F12/26
摘要： Compounds of the formula: ##STR1## where Q is a polymerizable olefin substituent;Ar is an aromatic moiety;C.sup..alpha. is the .alpha. carbon;R.sup.1 and R.sup.2 are independently hydrogen or aliphatic groups; andZ is a halogen, oxygen-containing, nitrogen-containing or sulfur-containing substituent complying with one of the formulae: --X, --OR, --SR or --NR.sub.2, wherein X is a halogen and each R is independently a hydrogen atom or an aliphatic moiety;contain azo groups which are stable with respect to thermal decompositon at high temperatures (180.degree. C. to 240.degree. C. and beyond) in the absence of moderate light, so that such compounds may be polymerized and processed at ordinary polystyrene process temperatures. However, the azo group in those compounds or in polymers made from them decomposes to initiate free radical polymerization at temperatures of 100.degree. C. to 120.degree. C. or less in the presence of moderate light.
摘要翻译：下式的化合物：其中Q是可聚合烯烃取代基; Ar是芳族部分; C alpha是α碳; R1和R2独立地是氢或脂族基团; 并且Z是符合以下通式之一的卤素，含氧，含氮或含硫取代基：-X，-OR，-SR或-NR2，其中X是卤素，并且每个R独立地是氢原子或脂族部分; 包含在不存在中等光照的情况下在高温（180℃至240℃以上）相对于热分解稳定的偶氮基团，使得这些化合物可以在普通聚苯乙烯工艺温度下聚合和加工。然而，这些化合物中的偶氮基团或由它们制备的聚合物中的偶氮基团在温和的光照下在100℃至120℃或更低的温度下分解引发自由基聚合。

7. 发明授权

US08789665B2 Carbon fiber reinforced carbon matrix composite for brake pad back plate 有权
标题翻译：用于刹车片背板的碳纤维增强碳基复合材料
公开(公告)号：US08789665B2
公开(公告)日：2014-07-29
申请号：US12560714
申请日：2009-09-16
申请人： Lawrence Frank Gilboy , Richard A. Wolf , Aaron M. Morey
发明人： Lawrence Frank Gilboy , Richard A. Wolf , Aaron M. Morey
IPC分类号： F16D69/00
CPC分类号： F16D65/092 , F16D69/04 , F16D2069/0433 , F16D2069/0441 , F16D2069/045 , F16D2069/0466 , F16D2069/0483 , F16D2069/0491 , F16D2200/0052 , F16D2200/0069 , F16D2250/0069 , Y10T29/49826
摘要： A brake pad assembly is provided, including a friction lining providing a wear surface for contacting a brake rotor and a back plate coupled to the friction lining. The back plate is made of a carbon fiber reinforced carbon matrix composite. In one example, a majority of the carbon fibers of the back plate are oriented in a x-y in-plane direction resulting in a structure where the thermal conductivity is at least 2 times greater in the x-y in-plane direction versus a z through-plane direction. In another example, the back plate is provided as at least one sheet of a carbon fiber reinforced carbon matrix composite. A method of manufacturing the brake pad assembly is also provided.
摘要翻译：提供了一种制动衬块组件，其包括摩擦衬片，其提供用于接触制动转子和联接到摩擦衬里的后板的磨损表面。背板由碳纤维增强碳基复合材料制成。在一个实例中，背板的大部分碳纤维在xy平面方向上取向，从而得到其中xy平面方向上的热传导率至少比通过平面方向至少大2倍的结构。在另一个实例中，背板设置为至少一片碳纤维增强碳基复合材料。还提供了一种制造该刹车片组件的方法。

8. 发明授权

US06559312B2 Intermediates useful for the preparation of antihistaminic piperidine derivatives 失效
标题翻译：用于制备抗组胺型哌啶衍生物的中间体
公开(公告)号：US06559312B2
公开(公告)日：2003-05-06
申请号：US09731654
申请日：2000-12-08
申请人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
发明人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
IPC分类号： C07D21122
CPC分类号： C07D295/185 , C07C33/46 , C07C45/46 , C07C45/63 , C07C45/65 , C07C45/673 , C07C49/792 , C07C49/798 , C07C49/80 , C07C49/813 , C07C49/82 , C07C49/825 , C07C49/83 , C07C49/835 , C07C49/86 , C07C59/86 , C07C59/88 , C07C69/007 , C07C69/738 , C07C235/78 , C07C255/16 , C07C259/06 , C07C2601/02 , C07D211/22 , C07D401/06 , C07D401/10
摘要： The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents —C(═O)— or —CH(OH)—; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer of 0 or 1; R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, m is an integer 0.
摘要翻译：本发明涉及一种新的中间体和方法，其可用于制备W代表-C（= O） - 或-CH（OH） - 的某些抗组胺型哌啶衍生物; R 1表示氢或羟基; R 2表示氢 R 1和R 2一起形成在具有R 1和R 2的碳原子之间的第二个键; n是1至5的整数; m是0或1的整数; R 3是-COOH或-COO烷基，其中烷基部分具有 1至6个碳原子，并且是直链或支链的，每个A是氢或羟基; 其药学上可接受的盐和单独的光学异构体，条件是其中R 1和R 2一起形成在具有R 1和R 2的碳原子之间或其中R 1表示羟基的第二个键，m是整数0。

9. 发明授权

US06552200B2 Intermediates useful for the preparation of antihistaminic piperidine derivatives 失效
标题翻译：用于制备抗组胺型哌啶衍生物的中间体
公开(公告)号：US06552200B2
公开(公告)日：2003-04-22
申请号：US09725259
申请日：2000-11-29
申请人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
发明人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
IPC分类号： C07D21122
CPC分类号： C07D295/185 , C07C33/46 , C07C45/46 , C07C45/63 , C07C45/65 , C07C45/673 , C07C49/792 , C07C49/798 , C07C49/80 , C07C49/813 , C07C49/82 , C07C49/825 , C07C49/83 , C07C49/835 , C07C49/86 , C07C59/86 , C07C59/88 , C07C69/007 , C07C69/738 , C07C235/78 , C07C255/16 , C07C259/06 , C07C2601/02 , C07D211/22 , C07D401/06 , C07D401/10
摘要： The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents —C(═O)— or —CH(OH)—; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1represented hydroxy, n is an integer 0.
摘要翻译：本发明涉及一种新的中间体和方法，其可用于制备W代表-C（= O） - 或-CH（OH） - 的某些抗组胺型哌啶衍生物; R 1表示氢或羟基; R 2表示氢 R 1和R 2一起形成在具有R 1和R 2的碳原子之间的第二个键; n是1至5的整数; m是整数0或1; R 3是-COOH或-COO烷基，其中烷基部分具有 1至6个碳原子，并且是直链或支链的，每个A是氢或羟基; 其药学上可接受的盐和单独的光学异构体，条件是其中R 1和R 2一起形成在具有R 1和R 2的碳原子之间或其中R 1表示羟基，n为整数0的第二个键。

10. 发明授权

US06479663B2 Intermediates useful for the preparation of antihistaminic piperidine derivatives 失效
标题翻译：用于制备抗组胺型哌啶衍生物的中间体
公开(公告)号：US06479663B2
公开(公告)日：2002-11-12
申请号：US09726625
申请日：2000-12-01
申请人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
发明人： Richard C. Krauss , Robert M. Strom , Carey L. Scortichini , William J. Kruper , Richard A. Wolf , Weishi W. Wu , Albert A. Carr , David A. Hay , Duane E. Rudisill , Gianbattista Panzone
IPC分类号： C07D21114
CPC分类号： C07D295/185 , C07C33/46 , C07C45/46 , C07C45/63 , C07C45/65 , C07C45/673 , C07C49/792 , C07C49/798 , C07C49/80 , C07C49/813 , C07C49/82 , C07C49/825 , C07C49/83 , C07C49/835 , C07C49/86 , C07C59/86 , C07C59/88 , C07C69/007 , C07C69/738 , C07C235/78 , C07C255/16 , C07C259/06 , C07C2601/02 , C07D211/22 , C07D401/06 , C07D401/10
摘要： The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents —C(═O)— or —CH(OH)—; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy m is an integer 0.
摘要翻译：本发明涉及一种新的中间体和方法，其可用于制备W代表-C（= O） - 或-CH（OH） - 的某些抗组胺型哌啶衍生物; R 1表示氢或羟基; R 2表示氢 R 1和R 2一起形成在具有R 1和R 2的碳原子之间的第二个键; n是1至5的整数; m是整数0或1; R 3是-COOH或-COO烷基，其中烷基部分具有 1至6个碳原子，并且是直链或支链的，每个A是氢或羟基; 其药学上可接受的盐和单独的光学异构体，条件是其中R 1和R 2一起形成在具有R 1和R 2的碳原子之间或其中R 1表示羟基的整数为0的第二个键。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式